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Searching for up to 100 curated homologs for WP_011384085.1 NCBI__GCF_000009985.1:WP_011384085.1 (190 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

padE / Q8L3B3 phenylglyoxylate dehydrogenase (acylating) subunit PadE (EC 1.2.1.58) from Aromatoleum evansii (see 2 papers)
PADE_AROEV / Q8L3B3 NADH-dependent phenylglyoxylate dehydrogenase subunit gamma; Phenylglyoxylate:NAD oxidoreductase; Phenylglyoxylate:acceptor oxidoreductase; EC 1.2.1.58 from Aromatoleum evansii (Azoarcus evansii) (see paper)
    57% identity, 100% coverage of query (239 bits)

Q51799 pyruvate synthase (subunit 1/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    48% identity, 97% coverage of query (162 bits)

W8CQB1 pyruvate synthase (subunit 2/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 2/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    48% identity, 97% coverage of query (159 bits)

porC / O27772 pyruvate synthase subunit γ (EC 1.2.7.1) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 7 papers)
    47% identity, 96% coverage of query (154 bits)

PORC_METTM / P80902 Pyruvate synthase subunit PorC; Pyruvate oxidoreductase gamma chain; POR; Pyruvic-ferredoxin oxidoreductase subunit gamma; EC 1.2.7.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    46% identity, 95% coverage of query (147 bits)

P80523 pyruvate synthase (subunit 2/4) (EC 1.2.7.1) from Methanosarcina barkeri (see paper)
    42% identity, 93% coverage of query (141 bits)

Q9P9E7 pyruvate synthase (subunit 2/5) (EC 1.2.7.1) from Methanococcus maripaludis (see paper)
    44% identity, 96% coverage of query (139 bits)

porC / O05650 pyruvate:ferredoxin oxidoreductase γ subunit (EC 1.2.7.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 7 papers)
O05650 pyruvate synthase (subunit 2/4) (EC 1.2.7.1) from Thermotoga maritima (see 2 papers)
    39% identity, 94% coverage of query (117 bits)

D3DIA3 2-oxoglutarate synthase (subunit 3/5) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 2 papers)
    31% identity, 82% coverage of query (80.9 bits)

Build an alignment

Build an alignment for WP_011384085.1 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

porG / Q9LBF7 pyruvate:ferredoxin oxidoreductase γ subunit (EC 1.2.7.1) from Hydrogenobacter thermophilus (see 2 papers)
D3DJJ8 pyruvate synthase (subunit 1/2) (EC 1.2.7.1) from Hydrogenobacter thermophilus (see paper)
porG / BAA95607.1 pyruvate:ferredoxin oxidoreductase gamma subunit from Hydrogenobacter thermophilus (see paper)
    29% identity, 83% coverage of query (60.5 bits)

KORC_METTM / P80906 2-oxoglutarate synthase subunit KorC; 2-ketoglutarate oxidoreductase gamma chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit gamma; EC 1.2.7.3 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    30% identity, 83% coverage of query (54.7 bits)

korG / Q6LXN4 2-oxoglutarate ferredoxin oxidoreductase γ subunit (EC 1.2.7.3) from Methanococcus maripaludis (strain S2 / LL) (see 2 papers)
    28% identity, 92% coverage of query (52.8 bits)

Q6LZB5 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Methanococcus maripaludis (see paper)
    27% identity, 88% coverage of query (51.6 bits)

A0A097APA2 pyruvate synthase (EC 1.2.7.1) from Thermoanaerobacter kivui (see paper)
    27% identity, 76% coverage of query (51.6 bits)

I3VRD9 pyruvate synthase (EC 1.2.7.1) from Thermoanaerobacterium saccharolyticum (see paper)
    26% identity, 90% coverage of query (50.1 bits)

5exdH / Q2RI40 Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-di-oxido-methyl-tpp (coom-tpp) intermediate (see paper)
    27% identity, 86% coverage of query (47.4 bits)

VORA_METTM / P80907 Ketoisovalerate oxidoreductase subunit VorA; VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha; EC 1.-.-.- from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    30% identity, 84% coverage of query (47.4 bits)

IORB_METTM / P80911 Indolepyruvate oxidoreductase subunit IorB; IOR; Indolepyruvate ferredoxin oxidoreductase subunit beta; EC 1.2.7.8 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    28% identity, 76% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory