Searching for up to 100 curated homologs for WP_011384687.1 NCBI__GCF_000009985.1:WP_011384687.1 (338 a.a.)
Found high-coverage hits (≥70%) to 43 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
A9CHR2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
31% identity, 82% coverage of query (139 bits)
Build an alignment for WP_011384687.1 and 1 homologs with ≥ 30% identity
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dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
29% identity, 85% coverage of query (103 bits)
dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
29% identity, 82% coverage of query (97.1 bits)
DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see 2 papers)
29% identity, 86% coverage of query (95.9 bits)
DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti (see 2 papers)
27% identity, 86% coverage of query (95.5 bits)
4i7wA / F0L8Z6 Agrobacterium tumefaciens dhdps with lysine and pyruvate
29% identity, 86% coverage of query (93.2 bits)
4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
27% identity, 87% coverage of query (91.7 bits)
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
27% identity, 87% coverage of query (91.7 bits)
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
27% identity, 87% coverage of query (91.7 bits)
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
27% identity, 87% coverage of query (91.7 bits)
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
27% identity, 87% coverage of query (91.7 bits)
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
27% identity, 87% coverage of query (91.7 bits)
Q3M723 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Trichormus variabilis (see paper)
26% identity, 86% coverage of query (87.8 bits)
5ktlA / Q3M723 Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
26% identity, 86% coverage of query (87.4 bits)
DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
27% identity, 75% coverage of query (87.4 bits)
7lvlA / A0A0F4VK59 Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
27% identity, 83% coverage of query (86.7 bits)
7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
27% identity, 83% coverage of query (86.7 bits)
dapA / P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum (see paper)
dapA / CAA79714.1 dihydrodipicolinate synthase from Corynebacterium glutamicum (see paper)
31% identity, 84% coverage of query (84.7 bits)
Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
27% identity, 75% coverage of query (84.0 bits)
1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
28% identity, 74% coverage of query (82.8 bits)
DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
28% identity, 74% coverage of query (82.8 bits)
5ud6C / M1V4H9 Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
27% identity, 86% coverage of query (78.6 bits)
YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
26% identity, 75% coverage of query (77.8 bits)
dapA / CAA92211.1 dihydrodipicolinate synthase from Prochlorococcus marinus (see paper)
29% identity, 84% coverage of query (72.4 bits)
KDGA_SACS2 / Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus (see paper)
25% identity, 84% coverage of query (70.5 bits)
kdgA / O54288 KDG-aldolase subunit (EC 4.1.2.28; EC 4.1.2.18; EC 4.1.2.51) from Saccharolobus solfataricus (see 2 papers)
KDGA_SACSO / O54288 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (Sulfolobus solfataricus) (see 4 papers)
O54288 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14); 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus (see 8 papers)
25% identity, 84% coverage of query (70.5 bits)
6g3zA / O54288 Sulfolobus sulfataricus 2-keto-3-deoxygluconate (kdg) aldolase complex with d-kdpg (see paper)
25% identity, 84% coverage of query (70.1 bits)
1w3tA Sulfolobus solfataricus 2-keto-3-deoxygluconate (kdg) aldolase complex with d-kdgal, d-glyceraldehyde and pyruvate
25% identity, 84% coverage of query (70.1 bits)
1w3nA Sulfolobus solfataricus 2-keto-3-deoxygluconate (kdg) aldolase complex with d-kdg
25% identity, 84% coverage of query (70.1 bits)
1w3iA Sulfolobus solfataricus 2-keto-3-deoxygluconate (kdg) aldolase complex with pyruvate
25% identity, 84% coverage of query (70.1 bits)
KDGA_SULAC / Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Sulfolobus acidocaldarius (see 2 papers)
2nuyA / Q4JC35 2-keto-3-deoxygluconate aldolase from sulfolobus acidocaldarius in complex with pyruvate (see paper)
26% identity, 83% coverage of query (69.7 bits)
6h7sA Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase t157v/a198l variant in complex with l-2-keto-3deoxy-gluconate
25% identity, 84% coverage of query (67.0 bits)
6gv2B Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase y103f,y130f, a198f variant in complex with l-2-keto, 3-deoxy-galactonate
24% identity, 84% coverage of query (64.7 bits)
Q8A3Z0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacteroides thetaiotaomicron (see paper)
23% identity, 80% coverage of query (61.6 bits)
B9DIJ2 N-acetylneuraminate lyase (EC 4.1.3.3) from Staphylococcus carnosus (see paper)
21% identity, 80% coverage of query (60.8 bits)
A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
25% identity, 82% coverage of query (60.1 bits)
HOGA1_BOVIN / Q0P5I5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Bos taurus (Bovine) (see 2 papers)
Q0P5I5 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) from Bos taurus (see paper)
26% identity, 78% coverage of query (59.3 bits)
A0A2P1G7E2 N-acetylneuraminate lyase (EC 4.1.3.3) from Mycoplasma sp. (see paper)
22% identity, 79% coverage of query (55.8 bits)
HOGA1 / Q86XE5 4-hydroxy-2-ketoglutarate aldolase subunit (EC 4.1.3.16) from Homo sapiens (see 6 papers)
HOGA1_HUMAN / Q86XE5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; Protein 569272; EC 4.1.3.16 from Homo sapiens (Human) (see 2 papers)
Q86XE5 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) from Homo sapiens (see 5 papers)
25% identity, 77% coverage of query (55.5 bits)
HOGA1_EMENI / Q5BD77 Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
AN1503 dihydrodipicolinate synthase-like protein AN1503; EC 4.-.-.- from Emericella nidulans (see paper)
29% identity, 82% coverage of query (55.1 bits)
CH_124068 putative dihydrodipicolinate synthase from Magnaporthe grisea 70-15 (see paper)
25% identity, 85% coverage of query (53.5 bits)
3na8A / Q9I6R5 Crystal structure of a putative dihydrodipicolinate synthetase from pseudomonas aeruginosa
26% identity, 72% coverage of query (53.1 bits)
SSA_0078 / A3CK37 N-acetylneuraminate lyase subunit (EC 4.1.3.3) from Streptococcus sanguinis (strain SK36) (see 3 papers)
26% identity, 70% coverage of query (50.8 bits)
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