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Searching for up to 100 curated homologs for WP_011384688.1 NCBI__GCF_000009985.1:WP_011384688.1 (279 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
    34% identity, 79% coverage of query (115 bits)

3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
    30% identity, 76% coverage of query (111 bits)

5kkwA / Q4FLR5 Crystal structure of sar11_1068 bound to a sulfobetaine (3-(1- methylpiperidinium-1-yl)propane-1-sulfonate)
    30% identity, 81% coverage of query (100 bits)

PHEC_PSEAE / Q01269 Cyclohexadienyl dehydratase; EC 4.2.1.51; EC 4.2.1.91 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q01269 arogenate dehydratase (EC 4.2.1.91) from Pseudomonas aeruginosa (see 3 papers)
    31% identity, 80% coverage of query (94.7 bits)

Build an alignment

Build an alignment for WP_011384688.1 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AO356_00480 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    29% identity, 90% coverage of query (91.7 bits)

4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
    28% identity, 76% coverage of query (81.6 bits)

4zv2A An ancestral arginine-binding protein bound to glutamine
    26% identity, 76% coverage of query (79.3 bits)

4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
    25% identity, 78% coverage of query (77.4 bits)

Ac3H11_2555 ABC transporter for L-Histidine, periplasmic substrate-binding component 1 from Acidovorax sp. GW101-3H11
    28% identity, 72% coverage of query (75.9 bits)

6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
    27% identity, 79% coverage of query (72.8 bits)

TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
    25% identity, 86% coverage of query (71.2 bits)

3vvdA / Q72JG5 Crystal structure of ttc0807 complexed with ornithine (see paper)
    25% identity, 79% coverage of query (70.9 bits)

3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec)
    25% identity, 79% coverage of query (70.9 bits)

3vvfA Crystal structure of ttc0807 complexed with arginine
    25% identity, 79% coverage of query (70.9 bits)

3vveA Crystal structure of ttc0807 complexed with lysine
    25% identity, 79% coverage of query (70.9 bits)

TC 3.A.1.3.6 / P35120 NocT aka ATU6027 aka AGR_PTI_67, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
    21% identity, 74% coverage of query (62.0 bits)

GLNH_BACSU / O34563 ABC transporter glutamine-binding protein GlnH from Bacillus subtilis (strain 168) (see paper)
    23% identity, 90% coverage of query (61.2 bits)

GlnH / b0811 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
GlnH / P0AEQ3 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 13 papers)
GLNH_ECOLI / P0AEQ3 Glutamine-binding periplasmic protein; GlnBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P0AEQ3 Glutamine-binding periplasmic protein GlnH aka B0811 aka GlnBP, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 7 papers)
glnH / GB|AAN79369.1 glutamine ABC transporter, periplasmic glutamine-binding protein GlnH from Escherichia coli (see 7 papers)
    22% identity, 77% coverage of query (59.7 bits)

4i62A / A0A0H2ZN67 1.05 angstrom crystal structure of an amino acid abc transporter substrate-binding protein abpa from streptococcus pneumoniae canada mdr_19a bound to l-arginine
    22% identity, 78% coverage of query (59.3 bits)

TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
    21% identity, 80% coverage of query (57.0 bits)

HISJ_CAMJE / Q46125 Probable histidine-binding protein; HBP; p29 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
    22% identity, 89% coverage of query (55.8 bits)

TCYA_BACSU / P42199 L-cystine-binding protein TcyA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.3.14 / P42199 TcyA (YckK), component of Uptake system for L-cystine from Bacillus subtilis (see 5 papers)
    24% identity, 85% coverage of query (55.1 bits)

2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
    23% identity, 81% coverage of query (52.8 bits)

8b5dA Exploring the ligand binding and conformational dynamics of receptor domain 1 of the abc transporter glnpq
    24% identity, 72% coverage of query (43.5 bits)

2v25A / Q0P9X8 Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
    23% identity, 81% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory