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Searching for up to 100 curated homologs for WP_011384963.1 AMB_RS12995 C4-dicarboxylate ABC transporter substrate-binding protein (187 a.a.)

Found high-coverage hits (≥70%) to 3 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.56.3.4 / D5ATK0 Tripartite ATP-independent periplasmic transporter, DctQ-2 component, component of The 2-ketomonocarboxylate transporter (presented in order of affinity - 2-oxovalerate [highest affinity, KD=0.1 μM], 2-oxoisovalerate, 2-oxobutyrate, 2-oxoisocaproate, 2-oxo-3-methylvalerate, pyruvate [lowest affinity, KD=3 μM]) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
    56% identity, 95% coverage of query (197 bits)

TC 2.A.56.3.3 / Q8YSQ8 Alr3026 protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
    42% identity, 94% coverage of query (148 bits)

TC 2.A.56.3.1 / P74225 GtrA aka SLL1102, component of Tripartite glutamate:Na+ symporter (see paper)
    43% identity, 89% coverage of query (143 bits)

Build an alignment

Build an alignment for WP_011384963.1 and 3 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory