Searching for up to 100 curated homologs for WP_011385006.1 NCBI__GCF_000009985.1:WP_011385006.1 (554 a.a.)
Found high-coverage hits (≥70%) to 35 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PS417_08865 large component of pyruvate transporter (actP-like) from Pseudomonas simiae WCS417
60% identity, 100% coverage of query (663 bits)
YjcG / b4067 acetate/glycolate:cation symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
actP / P32705 acetate/glycolate:cation symporter from Escherichia coli (strain K12) (see 5 papers)
ACTP_ECOLI / P32705 Cation/acetate symporter ActP; Acetate permease; Acetate transporter ActP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.21.7.2 / P32705 Acetate/glyoxylate permease, ActP from Escherichia coli (see 6 papers)
59% identity, 100% coverage of query (662 bits)
Pf6N2E2_5849 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N2E2
60% identity, 100% coverage of query (657 bits)
Pf1N1B4_3673 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N1B4
59% identity, 100% coverage of query (655 bits)
TC 2.A.21.7.4 / D5AU53 Acetate uptake permease, ActP1; also takes up tellurite from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
61% identity, 96% coverage of query (640 bits)
AZOBR_RS02940 large component of pyruvate transporter (actP-like) from Azospirillum brasilense Sp245
58% identity, 96% coverage of query (634 bits)
TC 2.A.21.7.1 / O50471 Phenylacetate permease, Ppa from Pseudomonas putida (see paper)
61% identity, 94% coverage of query (622 bits)
TC 2.A.21.7.5 / D5APM1 Acetate permease ActP-2/ActP2/ActP3 from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
57% identity, 98% coverage of query (615 bits)
MCTC_CORGL / Q8NS49 Monocarboxylic acid transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 2.A.21.7.3 / Q8NS49 Pyruvate/acetate/propionate: H+ symporter, MctC (DhlC; cg0953) from Corynebacterium glutamicum (see paper)
44% identity, 94% coverage of query (363 bits)
Build an alignment for WP_011385006.1 and 9 homologs with ≥ 30% identity
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Sama_1523 actP-like component of lactate uptake system from Shewanella amazonensis SB2B
26% identity, 92% coverage of query (133 bits)
Shew_2371 actP-like component of L-lactate and L-malate uptake system from Shewanella loihica PV-4
26% identity, 91% coverage of query (133 bits)
PUTP_BACSU / P94392 High-affinity proline transporter PutP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.21.2.4 / J7JIE8 The high affinity nutritional proline uptake porter, PutP from Bacillus subtilis QB928
26% identity, 79% coverage of query (110 bits)
OPUE_BACSU / O06493 Osmoregulated proline transporter OpuE; Osmoprotectant uptake; Proline uptake system from Bacillus subtilis (strain 168) (see 2 papers)
TC 2.A.21.2.5 / M1TZ79 Proline uptake porter, OpuE (YerK) from Bacillus subtilis subsp. subtilis 6051-HGW
opuE / AAB72182.1 OpuE from Bacillus subtilis (see paper)
24% identity, 89% coverage of query (107 bits)
Psest_3078 L-proline:Na+ symporter from Pseudomonas stutzeri RCH2
26% identity, 82% coverage of query (105 bits)
PutC / b1015 proline:Na+ symporter from Escherichia coli K-12 substr. MG1655 (see 7 papers)
putP / P07117 proline:Na+ symporter from Escherichia coli (strain K12) (see 12 papers)
PUTP_ECOLI / P07117 Sodium/proline symporter; Proline carrier; Proline permease; Propionate transporter from Escherichia coli (strain K12) (see 9 papers)
TC 2.A.21.2.1 / P07117 Proline:Na+ symporter, PutP from Escherichia coli (see 12 papers)
27% identity, 83% coverage of query (99.0 bits)
TC 2.A.21.2.3 / Q9I5F5 L-proline uptake porter, PutP from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
26% identity, 93% coverage of query (94.4 bits)
PUTP_SALTY / P10502 Sodium/proline symporter; Proline permease from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
27% identity, 83% coverage of query (93.2 bits)
putP / AAA79365.1 proline permease homolog from Staphylococcus aureus (see paper)
26% identity, 89% coverage of query (91.3 bits)
PUTP_STAA8 / Q2FWY7 Sodium/proline symporter; Proline permease from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
TC 2.A.21.2.2 / Q7A4Q7 Sodium/proline symporter (Proline permease) from Staphylococcus aureus (strain N315) (see paper)
27% identity, 87% coverage of query (89.0 bits)
TC 2.A.21.2.6 / O24896 High affinity proline-specific Na+:proline symporter, PutP (Rivera-Ordaz et al. 2013). Proline is a preferred source of energy for this microaerophilic bacterium. PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid from Helicobacter pylori (strain ATCC 700392 / 26695)
23% identity, 81% coverage of query (79.3 bits)
Echvi_1871 transporter for D-glucose/D-galactose/D-xylose/methyl-beta-D-galactopyranoside from Echinicola vietnamensis KMM 6221, DSM 17526
24% identity, 82% coverage of query (64.7 bits)
NANT_ALIF1 / Q5E733 N-acetylneuraminate transporter from Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri) (see paper)
21% identity, 73% coverage of query (63.9 bits)
SC5A3_MOUSE / Q9JKZ2 Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; Sodium/myo-inositol transporter 1; SMIT1; Solute carrier family 5 member 3 from Mus musculus (Mouse) (see 3 papers)
22% identity, 80% coverage of query (57.8 bits)
SGLT_VIBPH / P96169 Sodium/glucose cotransporter; Na(+)/glucose symporter from Vibrio parahaemolyticus (see paper)
TC 2.A.21.3.2 / P96169 Glucose or galactose:Na+ symporter, SglS or SglT of 543 aas and 14 TMSs (Turk et al. 2006). The 3.0 Å structure is known (Faham et al., 2008). Sodium exit causes a reorientation of transmembrane helix 1 that opens an inner gate required for substrate exit (Watanabe et al., 2010). The involvement of aromatic residue pi interactions, especially with Na+ binding, has been examined (see 3 papers)
AAF80602.1 Na+/galactose cotransporter SGLT from Vibrio parahaemolyticus (see paper)
21% identity, 80% coverage of query (55.8 bits)
SC5A3_CANLF / P31637 Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; Sodium/myo-inositol transporter 1; SMIT1; Solute carrier family 5 member 3 from Canis lupus familiaris (Dog) (Canis familiaris) (see 2 papers)
TC 2.A.21.3.5 / P31637 Myoinositol:Na+ symporter, SMIT1 from Canis familiaris (Dog) (see paper)
21% identity, 90% coverage of query (55.8 bits)
TC 2.A.21.3.14 / P53794 Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3) from Homo sapiens (see 3 papers)
21% identity, 90% coverage of query (53.1 bits)
MCTP_RHIJ3 / Q1M7A2 Monocarboxylate transport permease protein from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
23% identity, 80% coverage of query (53.1 bits)
SC5A3_HUMAN / P53794 Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; Sodium/myo-inositol transporter 1; SMIT1; Solute carrier family 5 member 3 from Homo sapiens (Human) (see 4 papers)
21% identity, 90% coverage of query (52.8 bits)
SC5A4_RAT / D3ZIS0 Solute carrier family 5 member 4 from Rattus norvegicus (Rat) (see paper)
20% identity, 82% coverage of query (50.8 bits)
PanF / b3258 pantothenate:Na+ symporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
panF / P16256 pantothenate:Na+ symporter from Escherichia coli (strain K12) (see 3 papers)
PANF_ECOLI / P16256 Sodium/pantothenate symporter; Pantothenate permease from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.21.1.1 / P16256 Pantothenate:Na+ symporter, PanF from Escherichia coli (see 5 papers)
panF / GB|AAC76290.2 sodium/pantothenate symporter from Escherichia coli K12 (see 5 papers)
20% identity, 78% coverage of query (50.8 bits)
SC5A7_CAEEL / O02228 High-affinity choline transporter 1 from Caenorhabditis elegans (see paper)
24% identity, 80% coverage of query (49.7 bits)
SC5A4_HUMAN / Q9NY91 Probable glucose sensor protein SLC5A4; Solute carrier family 5 member 4 from Homo sapiens (Human) (see 4 papers)
TC 2.A.21.3.18 / Q9NY91 Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na+/glucose cotransporter 3) (Solute carrier family 5 member 4) from Homo sapiens (see paper)
19% identity, 83% coverage of query (49.3 bits)
SC5A1_RABIT / P11170 Sodium/glucose cotransporter 1; Na(+)/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1 from Oryctolagus cuniculus (Rabbit) (see paper)
20% identity, 84% coverage of query (48.5 bits)
Echvi_1880 L-arabinose symporter from Echinicola vietnamensis KMM 6221, DSM 17526
22% identity, 93% coverage of query (48.5 bits)
BPHYT_RS22245 D-alanine transporter MctP from Burkholderia phytofirmans PsJN
23% identity, 81% coverage of query (47.4 bits)
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Lawrence Berkeley National Laboratory