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Searching for up to 100 curated homologs for WP_011386296.1 NCBI__GCF_000009985.1:WP_011386296.1 (223 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FZLA_CAUVN / A0A0H3CDY2 FtsZ-localized protein A; FtsZ-binding protein FzlA from Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus) (see 3 papers)
    47% identity, 100% coverage of query (191 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    33% identity, 86% coverage of query (91.7 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    32% identity, 89% coverage of query (86.7 bits)

Build an alignment

Build an alignment for WP_011386296.1 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    28% identity, 90% coverage of query (84.0 bits)

GTT2 / Q12390 glutathione transferase 2 monomer (EC 2.5.1.18) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 13 papers)
GST2_YEAST / Q12390 Glutathione S-transferase 2; GST-II; EC 2.5.1.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 91% coverage of query (71.6 bits)

3ergA / Q12390 Crystal structure of gtt2 from saccharomyces cerevisiae in complex with glutathione sulfnate (see paper)
    30% identity, 91% coverage of query (71.2 bits)

4gltA / Q1GZF4 Crystal structure of glutathione s-transferase mfla_2116 (target efi- 507160) from methylobacillus flagellatus kt with gsh bound
    29% identity, 91% coverage of query (71.2 bits)

3ibhA Crystal structure of saccharomyces cerevisiae gtt2 in complex with glutathione
    30% identity, 91% coverage of query (71.2 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    33% identity, 91% coverage of query (68.9 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    28% identity, 89% coverage of query (68.9 bits)

A4LAG9 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    29% identity, 90% coverage of query (67.0 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 78% coverage of query (67.0 bits)

gst3a / CAB38118.1 Glutathione transferase III(a) from Zea mays (see paper)
    32% identity, 91% coverage of query (66.6 bits)

GSTd1-5 / CAB03592.1 GSTD1-5 protein from Anopheles gambiae (see 2 papers)
    29% identity, 72% coverage of query (66.2 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    33% identity, 91% coverage of query (66.2 bits)

A0AEF0 glutathione transferase (EC 2.5.1.18) from Phytophthora infestans (see paper)
    31% identity, 88% coverage of query (65.9 bits)

GST1C_ANOGA / Q93112 Glutathione S-transferase 1, isoform C; AgGst1-alpha; Aggst1-5; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see paper)
    29% identity, 71% coverage of query (65.1 bits)

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    32% identity, 77% coverage of query (64.7 bits)

GST1 / AAA29287.1 glutathione transferase from Lucilia cuprina (see paper)
    27% identity, 86% coverage of query (64.7 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    29% identity, 72% coverage of query (64.3 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    25% identity, 94% coverage of query (64.3 bits)

GSTD2_DROME / Q9VG98 Glutathione S-transferase D2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
Q9VG98 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
    28% identity, 87% coverage of query (63.9 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    28% identity, 72% coverage of query (63.5 bits)

GSTE_PSEP1 / P82998 Glutathione S-transferase; EC 2.5.1.18 from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see paper)
    25% identity, 96% coverage of query (63.2 bits)

SSPA_COXBU / Q83AY0 Stringent starvation protein A homolog from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    29% identity, 93% coverage of query (62.8 bits)

Q60GK5 glutathione transferase (EC 2.5.1.18) from Bombyx mori (see paper)
    28% identity, 73% coverage of query (62.0 bits)

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    31% identity, 77% coverage of query (61.2 bits)

3qawA / B9VX79 Crystal structure of a glutathione-s-transferase from antarctic clam laternula elliptica in a complex with glutathione (see paper)
    26% identity, 93% coverage of query (60.8 bits)

3qagA / Q9H4Y5 Human glutathione transferase o2 with glutathione -new crystal form (see paper)
    25% identity, 91% coverage of query (60.5 bits)

Ac3H11_2306 Maleylacetoacetate isomerase (EC 5.2.1.2) from Acidovorax sp. GW101-3H11
    32% identity, 75% coverage of query (60.1 bits)

GSTD4_DROME / Q9VG96 Glutathione S-transferase D4; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    25% identity, 87% coverage of query (60.1 bits)

GSTD5_DROME / Q9VG95 Glutathione S-transferase D5; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 87% coverage of query (60.1 bits)

4nhzH / A5EI34 Crystal structure of glutathione transferase bbta-3750 from bradyrhizobium sp., Target efi-507290, with one glutathione bound
    28% identity, 89% coverage of query (59.7 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    27% identity, 92% coverage of query (59.7 bits)

3gh6A / Q9VGA1 Crystal structure of glutathione transferase dmgstd10 from drosophila melanogaster, in complex with glutathione (see paper)
    27% identity, 71% coverage of query (58.9 bits)

GSTD3_DROME / Q9VG97 Inactive glutathione S-transferase D3 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 77% coverage of query (58.9 bits)

5zwpA / P28338 Crystal structure of the delta-class glutathione transferase from musca domestica (see paper)
    27% identity, 72% coverage of query (58.2 bits)

GST1D_ANOGA / Q93113 Glutathione S-transferase 1, isoform D; AgGst1-alpha; Aggst1-1; Aggst1-6; Aggst2-1; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see 3 papers)
1pn9A / Q93113 Crystal structure of an insect delta-class glutathione s-transferase from a ddt-resistant strain of the malaria vector anopheles gambiae (see paper)
GSTd1-6 / CAB03593.1 GSTD1-6 protein, partial from Anopheles gambiae (see 2 papers)
    26% identity, 87% coverage of query (58.2 bits)

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    31% identity, 71% coverage of query (58.2 bits)

A0A023JBX8 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    25% identity, 91% coverage of query (57.8 bits)

GSTO2_HUMAN / Q9H4Y5 Glutathione S-transferase omega-2; GSTO-2; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 3 papers)
Q9H4Y5 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 3 papers)
    25% identity, 91% coverage of query (57.4 bits)

G7N132 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
    25% identity, 91% coverage of query (57.0 bits)

3f63A / Q9GN60 Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, in complex with s-hexyl glutathione (see paper)
    32% identity, 72% coverage of query (57.0 bits)

Q9GN60 glutathione transferase (EC 2.5.1.18) from Anopheles dirus (see 2 papers)
    32% identity, 72% coverage of query (57.0 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    24% identity, 71% coverage of query (57.0 bits)

6wegD Structure of ft (mgla-sspa)-ppgpp-pigr peptide complex
    25% identity, 91% coverage of query (57.0 bits)

GSTF8 / Q96266 glutathione S-transferase F8 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTF8_ARATH / Q96266 Glutathione S-transferase F8, chloroplastic; AtGSTF8; AtGSTF5; GST class-phi member 8; Glutathione S-transferase 6; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    28% identity, 87% coverage of query (56.6 bits)

YibF / b3592 glutathione transferase-like protein YibF from Escherichia coli K-12 substr. MG1655 (see 4 papers)
3r2qA / P0ACA1 Crystal structure analysis of yibf from e. Coli
yibF / RF|NP_418049 uncharacterized GST-like protein yibF from Escherichia coli K12 (see 2 papers)
    31% identity, 75% coverage of query (56.6 bits)

P0ACA1 Uncharacterized GST-like protein YibF from Escherichia coli (strain K12)
    31% identity, 75% coverage of query (56.6 bits)

3wywB / Q8N0B3 Structural characterization of catalytic site of a nilaparvata lugens delta-class glutathione transferase (see paper)
    29% identity, 71% coverage of query (56.2 bits)

5f06A / U5GTL0 Crystal structure of glutathione transferase f7 from populus trichocarpa (see paper)
    29% identity, 89% coverage of query (56.2 bits)

Q8N0B3 glutathione transferase (EC 2.5.1.18) from Nilaparvata lugens (see paper)
    29% identity, 71% coverage of query (56.2 bits)

TCHQD_ARATH / O80662 Glutathione S-transferase TCHQD; Protein tetrachlorohydroquinone dehalogenase-homolog; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    26% identity, 93% coverage of query (56.2 bits)

L7QHV5 glutathione transferase (EC 2.5.1.18) from Oncorhynchus kisutch (see paper)
    24% identity, 72% coverage of query (56.2 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    24% identity, 92% coverage of query (56.2 bits)

GSTD1_DROME / P20432 Glutathione S-transferase D1; DDT-dehydrochlorinase; EC 2.5.1.18; EC 4.5.1.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    29% identity, 71% coverage of query (56.2 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    24% identity, 92% coverage of query (56.2 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    24% identity, 92% coverage of query (56.2 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    24% identity, 92% coverage of query (56.2 bits)

5v3qA Human gsto1-1 complexed with ml175
    24% identity, 92% coverage of query (56.2 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    24% identity, 92% coverage of query (56.2 bits)

6mhbA Glutathione s-transferase omega 1 bound to covalent inhibitor 18
    24% identity, 92% coverage of query (56.2 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    24% identity, 92% coverage of query (56.2 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    24% identity, 92% coverage of query (56.2 bits)

1eemA Glutathione transferase from homo sapiens
    24% identity, 92% coverage of query (56.2 bits)

3makA / P20432 Crystal structure of glutathione transferase dmgstd1 from drosophila melanogaster, in complex with glutathione (see paper)
    29% identity, 71% coverage of query (55.8 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    24% identity, 92% coverage of query (55.8 bits)

4nhwD Crystal structure of glutathione transferase smc00097 from sinorhizobium meliloti, target efi-507275, with one glutathione bound per one protein subunit
    29% identity, 78% coverage of query (55.8 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    23% identity, 88% coverage of query (55.8 bits)

Q2YFE6 glutathione transferase (EC 2.5.1.18) from Sarcoptes scabiei (see paper)
    26% identity, 87% coverage of query (55.8 bits)

3ublA / Q8F2Y8 Crystal structure of glutathione transferase (target efi-501770) from leptospira interrogans with gsh bound
    24% identity, 89% coverage of query (55.8 bits)

4xt0A / G2IN92 Crystal structure of beta-etherase ligf from sphingobium sp. Strain syk-6 (see paper)
    26% identity, 84% coverage of query (55.8 bits)

A1YW90 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    26% identity, 88% coverage of query (55.8 bits)

6wmtS F. Tularensis rnaps70-(mgla-sspa)-ppgpp-pigr-igla DNA complex (see paper)
    25% identity, 90% coverage of query (55.8 bits)

4yquA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-31
    24% identity, 92% coverage of query (55.8 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    24% identity, 92% coverage of query (55.8 bits)

P43387 dichloromethane dehalogenase (EC 4.5.1.3) from Methylophilus sp. (see 9 papers)
dcmA / AAA25443.1 Dichloromethane Dehalogenase / Glutathione S-Transferase from Methylophilus sp (see paper)
    24% identity, 90% coverage of query (55.5 bits)

ligF / P30347 LigF β-etherase monomer from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see 3 papers)
ligF / BAA02031.1 beta-etherase from Sphingomonas paucimobilis (see 2 papers)
    26% identity, 84% coverage of query (55.5 bits)

AO353_15560 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E3
    31% identity, 72% coverage of query (55.1 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    27% identity, 70% coverage of query (54.7 bits)

4i97A / R4S8C5 The crystal structure of glutathione s-transferase sniggstd1a from scaptomyza nigrita in complex with glutathione
    26% identity, 71% coverage of query (54.7 bits)

3zmkB / G0XSZ1 Anopheles funestus glutathione-s-transferase epsilon 2 (gste2) protein structure from different alelles: a single amino acid change confers high level of ddt resistance and cross resistance to permethrin in a major malaria vector in africa (see paper)
    25% identity, 73% coverage of query (54.3 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    32% identity, 76% coverage of query (54.3 bits)

4kdxA / B1FZ96 Crystal structure of a glutathione transferase family member from burkholderia graminis, target efi-507264, bound gsh, ordered domains, space group p21, form(1)
    29% identity, 77% coverage of query (54.3 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    27% identity, 79% coverage of query (53.5 bits)

6hjsA / R7S6N2 Crystal structure of glutathione transferase omega 1c from trametes versicolor (see paper)
    26% identity, 80% coverage of query (53.1 bits)

4yavA Crystal structure of ligg in complex with b-glutathionyl- acetoveratrone (gs-av) from sphingobium sp. Strain syk-6
    29% identity, 84% coverage of query (53.1 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    31% identity, 76% coverage of query (53.1 bits)

4g10A / Q9WXJ9 Ligg from sphingobium sp. Syk-6 is related to the glutathione transferase omega class (see paper)
    29% identity, 84% coverage of query (52.8 bits)

3g7iB Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, with glutathione complexed in one subunit
    30% identity, 72% coverage of query (52.8 bits)

6srbB / A0A1M2V359 Crystal structure of glutathione transferase omega 3c from trametes versicolor (see paper)
    29% identity, 74% coverage of query (52.0 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    23% identity, 92% coverage of query (52.0 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    23% identity, 92% coverage of query (51.6 bits)

4jedA / B1M0X3 Crystal structure of glutathione s-transferase mrad2831_1084 (target efi-507060) from methylobacterium radiotolerans jcm 2831, complex with glutathione sulfonate
    30% identity, 90% coverage of query (51.6 bits)

4pnfB / Q7JZM3 Glutathione s-transferase from drosophila melanogaster - isozyme e6 (see paper)
    24% identity, 89% coverage of query (51.2 bits)

4kh7B / Q8Z859 Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
    27% identity, 73% coverage of query (50.8 bits)

4ijiA Crystal structure of a glutathione transferase family member from psuedomonas fluorescens pf-5, target efi-900011, with bound s- (propanoic acid)-glutathione
    25% identity, 89% coverage of query (50.8 bits)

4id0B Crystal structure of a glutathione transferase family member from pseudomonas fluorescens pf-5, target efi-900011, with bound glutathione sulfinic acid (gso2h) and acetate
    25% identity, 89% coverage of query (50.8 bits)

4ibpA / Q4K4R5 Crystal structure of a glutathione transferase family member from pseudomonas fluorescens pf-5, target efi-900011, with bound glutathione
    25% identity, 89% coverage of query (50.8 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    28% identity, 76% coverage of query (50.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory