Searching for up to 100 curated homologs for WP_011386686.1 NCBI__GCF_000009985.1:WP_011386686.1 (232 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CBIO_RHOCB / O68106 Cobalt import ATP-binding protein CbiO; Energy-coupling factor transporter ATP-binding protein CbiO; ECF transporter A component CbiO; EC 7.2.2.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see 2 papers)
TC 3.A.1.23.8 / O68106 Cobalt import ATP-binding protein CbiO, component of Ni2+/Co2+ uptake porter, CbiMNOQ (CbiM, 222 aas, 5 TMSs; CbiN, 103 aas, 2 TMSs; CbiO, 280 aas, 0 TMSs; CbiQ, 244 aas, 5 TMSs) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
48% identity, 90% coverage of query (167 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
48% identity, 90% coverage of query (166 bits)
NIKO_RHOCB / D5AQY6 Nickel import ATP-binding protein NikO; Energy-coupling factor transporter ATP-binding protein NikO; ECF transporter A component NikO; EC 3.6.3.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
TC 3.A.1.23.7 / D5AQY6 Nickel import ATP-binding protein NikO, component of Ni2+, Co2+ uptake transporter, NikMNOQ (subunit sizes: NikMN, 347 aas, 9 TMSs; NikQ, 284 aas, 4 TMSs; NikO, 254 aas, 0 TMS from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
40% identity, 93% coverage of query (147 bits)
BIOM_RHIEC / Q2KBP5 Biotin transport ATP-binding protein BioM; Biotin ECF transporter A component BioM; EC 7.6.2.- from Rhizobium etli (strain CFN 42 / ATCC 51251) (see paper)
44% identity, 73% coverage of query (134 bits)
ECFA2_LACLM / A2RI02 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
35% identity, 92% coverage of query (130 bits)
ECFA1_LACP3 / Q035B2 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) (Lactobacillus paracasei) (see paper)
36% identity, 89% coverage of query (130 bits)
TC 3.A.1.23.1 / Q79CI9 Nickel transport ATP-binding protein UreO, component of Nickel (Ni2+) porter from Streptococcus salivarius (see paper)
34% identity, 80% coverage of query (126 bits)
cbiO2 / Q18CI9 energy-coupling factor transporter ATP-bindind protein 2 from Clostridioides difficile (strain 630) (see 10 papers)
33% identity, 92% coverage of query (126 bits)
TC 3.A.1.26.10 / TC 3.A.1.26.7 / Q839D5 Cobalt import ATP-binding protein CbiO 1, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2 from Enterococcus faecalis (see paper)
37% identity, 81% coverage of query (125 bits)
cbiO1 / Q18CJ0 energy-coupling factor transporter ATP-bindind protein 1 from Clostridioides difficile (strain 630) (see 10 papers)
33% identity, 91% coverage of query (125 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
36% identity, 91% coverage of query (123 bits)
TC 3.A.1.26.10 / TC 3.A.1.26.7 / Q839D4 Cobalt import ATP-binding protein CbiO 2, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2 from Enterococcus faecalis (see paper)
34% identity, 99% coverage of query (121 bits)
LARO_LACPL / Q890D1 Nickel import ATP-binding protein LarO; Energy-coupling factor transporter ATP-binding protein LarO; ECF transporter A component LarO; Nickel transport ATP-binding protein; EC 7.2.2.- from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
35% identity, 88% coverage of query (120 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
35% identity, 91% coverage of query (118 bits)
ECFA1_LEUMM / Q03ZL6 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) (see 2 papers)
33% identity, 90% coverage of query (118 bits)
ECFA2_LEUMM / Q03ZL5 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) (see 2 papers)
32% identity, 90% coverage of query (118 bits)
5d3mB Folate ecf transporter: amppnp bound state
35% identity, 91% coverage of query (118 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
34% identity, 84% coverage of query (117 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
35% identity, 84% coverage of query (117 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
34% identity, 91% coverage of query (117 bits)
TC 3.A.1.26.9 / TC 3.A.1.28.2 / Q03PY5 Energy-coupling factor transporter ATP-binding protein EcfA1, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ) from Lactobacillus brevis (strain ATCC 367 / JCM 1170)
35% identity, 99% coverage of query (116 bits)
ECFA2_LACP3 / Q035B3 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) (Lactobacillus paracasei) (see paper)
35% identity, 80% coverage of query (116 bits)
TC 3.A.1.25.1 / Q6GUB2 ATP-binding protein BioM, component of The biotin uptake porter (binding receptor lacking) (see also the VUT or ECF family; BioY; 2.A.88.1.1) (Rodionov et al., 2006; Hebbeln et al., 2007). BioN (the EcfT component of the biotin transporter) appears to be required for intramolecular signaling and subunit assembly (Neubauer et al., 2009). The Ala-Arg-Ser and Ala-Arg-Gly signatures in BioN are coupling sites to the BioM ATPases from Rhizobium etli (see paper)
41% identity, 73% coverage of query (115 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 92% coverage of query (114 bits)
ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168) (see paper)
33% identity, 91% coverage of query (114 bits)
TC 3.A.1.26.9 / TC 3.A.1.28.2 / Q03PY6 Energy-coupling factor transporter ATP-binding protein EcfA2, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ) from Lactobacillus brevis (strain ATCC 367 / JCM 1170)
34% identity, 91% coverage of query (114 bits)
8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
34% identity, 84% coverage of query (114 bits)
TC 3.A.1.26.5 / A7NRG0 ABC transporter related, component of ThiW/CbiQ/CbiO homologues (ThiW: 174 aas; 5 putative TMSs) from Roseiflexus castenholzii (strain DSM 13941 / HLO8)
39% identity, 84% coverage of query (112 bits)
GlnQ / b0809 L-glutamine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GlnQ / P10346 L-glutamine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see paper)
GLNQ_ECOLI / P10346 Glutamine transport ATP-binding protein GlnQ from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P10346 GlnQ aka B0809, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 5 papers)
glnQ / GB|ABB65374.1 glutamine ABC transporter, ATP-binding protein GlnQ from Escherichia coli K12 (see 5 papers)
35% identity, 91% coverage of query (112 bits)
ECFA2_THEMA / Q9WY65 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 7.-.-.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
TC 3.A.1.25.5 / Q9WY65 Putative ABC transporter ATP-binding protein TM_0222, component of Biotin/Riboflavin ECF transport system, EcfAA'T/RibU/BioY (Karpowich and Wang 2013). RibU binds riboflavin with high affinity, and the protein-substrate complex is exceptionally stable in solution. The crystal structure of riboflavin-bound RibU reveals an electronegative binding pocket at the extracellular surface in which the substrate is completely buried from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
34% identity, 90% coverage of query (110 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
34% identity, 90% coverage of query (110 bits)
BIOM_RHOCB / D5ARH0 Biotin transport ATP-binding protein BioM; ECF transporter A component BioM; EC 7.6.2.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
TC 3.A.1.25.7 / D5ARH0 Biotin transport ATP-binding protein BioM, component of The riboflavin uptake system, BioMNY from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
40% identity, 78% coverage of query (109 bits)
TC 3.A.1.10.2 / P74127 FutC aka SLL1878, component of Ferric iron (Fe3+) porter (see paper)
38% identity, 77% coverage of query (109 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
36% identity, 86% coverage of query (108 bits)
2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
36% identity, 86% coverage of query (107 bits)
TcyN / b1917 cystine ABC transporter ATP binding subunit (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
tcyN / P37774 cystine ABC transporter ATP binding subunit (EC 7.4.2.12) from Escherichia coli (strain K12) (see 7 papers)
TCYN_ECOLI / P37774 L-cystine transport system ATP-binding protein TcyN; EC 7.4.2.12 from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.3.10 / P37774 YECC aka CysZ aka B1917, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 5 papers)
35% identity, 92% coverage of query (107 bits)
TauB / b0366 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TauB / Q47538 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli (strain K12) (see 3 papers)
TAUB_ECOLI / Q47538 Taurine import ATP-binding protein TauB; EC 7.6.2.7 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.17.1 / Q47538 TauB aka SSIB aka B0366, component of Taurine (2-aminoethane sulfonate) porter from Escherichia coli (see 4 papers)
35% identity, 88% coverage of query (107 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
34% identity, 90% coverage of query (107 bits)
TC 3.A.1.120.5 / Q2PGB8 The acetate resistance ABC acetate exporter from Acetobacter aceti (see paper)
39% identity, 90% coverage of query (106 bits)
ECFA1_LACLM / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.25.4 / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of The biotin uptake system, BioMNY. The 3-d structure of the EcfS subunit, BioY, at 2.1Å resolution is known (Berntsson et al., 2012). BioY and ThiT from L. lactis from Lactococcus lactis subsp. cremoris (strain MG1363)
34% identity, 77% coverage of query (106 bits)
BCEA_BACSU / O34697 Bacitracin export ATP-binding protein BceA from Bacillus subtilis (strain 168) (see 3 papers)
38% identity, 76% coverage of query (106 bits)
8g4cB / O34697 Bceabs atpgs high res tm (see paper)
38% identity, 76% coverage of query (106 bits)
GLUA_CORGL / P48243 Glutamate transport ATP-binding protein GluA; Glutamate uptake system protein GluA; EC 7.4.2.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48243 GluA aka CGL1950, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
33% identity, 91% coverage of query (106 bits)
7tchB Bceab e169q variant atp-bound conformation
37% identity, 77% coverage of query (105 bits)
PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
35% identity, 91% coverage of query (103 bits)
8w6iD / P0A9R7 Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
35% identity, 92% coverage of query (103 bits)
FtsE / b3463 cell division protein FtsE from Escherichia coli K-12 substr. MG1655 (see 9 papers)
FTSE_ECOLI / P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see 4 papers)
ftsE cell division ATP-binding protein ftsE from Escherichia coli K12 (see 3 papers)
35% identity, 92% coverage of query (103 bits)
8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
34% identity, 92% coverage of query (102 bits)
TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
31% identity, 99% coverage of query (101 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
32% identity, 91% coverage of query (100 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
34% identity, 91% coverage of query (97.8 bits)
FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
31% identity, 91% coverage of query (97.8 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
34% identity, 91% coverage of query (97.8 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
32% identity, 91% coverage of query (97.4 bits)
8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
31% identity, 91% coverage of query (97.4 bits)
8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
31% identity, 91% coverage of query (97.4 bits)
4hluC / Q9X1Z1 Structure of the ecfa-a' heterodimer bound to adp (see paper)
32% identity, 85% coverage of query (96.3 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
31% identity, 91% coverage of query (96.3 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
31% identity, 91% coverage of query (96.3 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
31% identity, 91% coverage of query (96.3 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
31% identity, 91% coverage of query (95.1 bits)
8wm7C / Q8YZ76 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
35% identity, 91% coverage of query (94.7 bits)
8w9mC Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
34% identity, 91% coverage of query (92.8 bits)
4zirB Crystal structure of ecfaa' heterodimer bound to amppnp
32% identity, 85% coverage of query (92.8 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
33% identity, 88% coverage of query (91.3 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
32% identity, 84% coverage of query (91.3 bits)
ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
33% identity, 88% coverage of query (90.9 bits)
P0A9U3 Probable ATP-binding protein YbiT from Escherichia coli (strain K12)
30% identity, 93% coverage of query (90.9 bits)
YbiT / b0820 putative ATP-binding protein YbiT from Escherichia coli K-12 substr. MG1655 (see 7 papers)
YBIT_ECOL6 / P0A9U4 Probable ATP-binding protein YbiT from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
ybiT / MB|P0A9U3 uncharacterized ABC transporter ATP-binding protein ybiT from Escherichia coli K12 (see 2 papers)
30% identity, 93% coverage of query (90.9 bits)
8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
30% identity, 94% coverage of query (90.5 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
32% identity, 92% coverage of query (90.1 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
32% identity, 92% coverage of query (90.1 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
32% identity, 92% coverage of query (90.1 bits)
7lkzA Structure of atp-bound human abca4
32% identity, 88% coverage of query (89.7 bits)
7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
32% identity, 88% coverage of query (89.7 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
31% identity, 84% coverage of query (89.7 bits)
8buu9 / W1SM44 8buu9 (see paper)
33% identity, 84% coverage of query (89.7 bits)
LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
35% identity, 84% coverage of query (89.7 bits)
7arlD Lolcde in complex with lipoprotein and adp
35% identity, 84% coverage of query (89.7 bits)
7mdyC Lolcde nucleotide-bound
35% identity, 84% coverage of query (89.7 bits)
7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
34% identity, 84% coverage of query (88.6 bits)
7lkpA Structure of atp-free human abca4
32% identity, 87% coverage of query (88.6 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
32% identity, 87% coverage of query (88.2 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
30% identity, 84% coverage of query (88.2 bits)
8wm7D / Q8YZ75 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
33% identity, 84% coverage of query (87.8 bits)
7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
34% identity, 81% coverage of query (87.4 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
33% identity, 85% coverage of query (87.0 bits)
8w9mD Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
31% identity, 91% coverage of query (86.7 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
30% identity, 92% coverage of query (85.5 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
30% identity, 92% coverage of query (85.5 bits)
2olkA Abc protein artp in complex with adp-beta-s
30% identity, 92% coverage of query (85.5 bits)
2oljA Abc protein artp in complex with adp/mg2+
30% identity, 92% coverage of query (85.5 bits)
1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
31% identity, 91% coverage of query (85.1 bits)
Build an alignment for WP_011386686.1 and 93 homologs with ≥ 30% identity
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5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
29% identity, 90% coverage of query (85.1 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
32% identity, 84% coverage of query (84.0 bits)
6hrcB Outward-facing pglk with atpgammas bound
26% identity, 82% coverage of query (84.0 bits)
6hrcA / O86150 Outward-facing pglk with atpgammas bound (see paper)
26% identity, 82% coverage of query (84.0 bits)
5nbdA Pglk flippase in complex with inhibitory nanobody
26% identity, 82% coverage of query (84.0 bits)
ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
31% identity, 88% coverage of query (84.0 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
32% identity, 91% coverage of query (84.0 bits)
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Lawrence Berkeley National Laboratory