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Searching for up to 100 curated homologs for WP_011606228.1 NCBI__GCF_000058485.1:WP_011606228.1 (369 a.a.)

Found high-coverage hits (≥70%) to 44 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4n5vA Alternative substrates of mycobacterium tuberculosis anthranilate phosphoribosyl transferase
    52% identity, 96% coverage of query (257 bits)

4n93A Alternative substrates of mycobacterium tuberculosis anthranilate phosphoribosyl transferase
    52% identity, 96% coverage of query (257 bits)

TRPD_MYCTU / P9WFX5 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
A5U4M0 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Mycobacterium tuberculosis (see paper)
P9WFX5 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Mycobacterium tuberculosis (see 3 papers)
    52% identity, 96% coverage of query (253 bits)

5c2lA / P9WFX5 Magnesium soaked into the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4zokA Methylsulfonyl-containing inhibitor bound in the substrate capture site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4zofA Lobenzarit-like inhibitor bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4owoA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 6-fluoroanthranilate, prpp and magnesium
    52% identity, 96% coverage of query (253 bits)

4giuA Bianthranilate-like analogue bound in inner site of anthranilate phosphoribosyltransferase (anprt; trpd).
    52% identity, 96% coverage of query (253 bits)

4owmA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 3-fluoroanthranilate, prpp and magnesium
    52% identity, 96% coverage of query (253 bits)

4gkmA Bianthranilate-like analogue bound in the outer site of anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

3r6cA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs179)
    52% identity, 96% coverage of query (253 bits)

3qsaA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor tamu-a7)
    52% identity, 96% coverage of query (253 bits)

3qs8A Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs174)
    52% identity, 96% coverage of query (253 bits)

3qqsA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs172)
    52% identity, 96% coverage of query (253 bits)

1zvwA The crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesium
    52% identity, 96% coverage of query (253 bits)

3r88B Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs145)
    52% identity, 96% coverage of query (253 bits)

5c7sA Prpp complexed with two mn2+ in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4zojA Methylsulfanyl-containing inhibitor bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4owuA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 5-methylanthranilate, prpp and magnesium
    52% identity, 96% coverage of query (253 bits)

4owqA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 3-methylanthranilate, prpp and magnesium
    52% identity, 96% coverage of query (253 bits)

5c1rA Stereoisomer of prpp bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyl (anprt; trpd)
    52% identity, 96% coverage of query (253 bits)

4ownA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 5-fluoroanthranilate, prpp and magnesium
    52% identity, 96% coverage of query (244 bits)

4m0rA Trianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (anprt; trpd).
    52% identity, 96% coverage of query (244 bits)

3uu1A Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs142)
    51% identity, 96% coverage of query (244 bits)

4owsA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 4-methylanthranilate, prpp and magnesium
    51% identity, 96% coverage of query (238 bits)

4owvA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with anthranilate
    51% identity, 96% coverage of query (234 bits)

5bneA Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    51% identity, 96% coverage of query (230 bits)

5bo3B Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    49% identity, 96% coverage of query (229 bits)

5bo2A Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    50% identity, 96% coverage of query (228 bits)

trpD / AAB39009.1 anthranilate phosphoribosyltransferase from Bradyrhizobium japonicum (see paper)
    41% identity, 97% coverage of query (225 bits)

5bo3A Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
    50% identity, 96% coverage of query (223 bits)

trpD / AAD09118.1 anthranilate phosphoribosyltransferase from Rhodobacter sphaeroides (see paper)
    43% identity, 81% coverage of query (196 bits)

TRPD_XANCP / Q8PD71 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
    39% identity, 92% coverage of query (173 bits)

trpD / BAC65124.1 anthranilate phosphoribosyltransferase from Burkholderia multivorans (see paper)
    36% identity, 91% coverage of query (171 bits)

TRPD2_NOSS1 / Q8YXQ9 Anthranilate phosphoribosyltransferase 2; EC 2.4.2.18 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
    36% identity, 81% coverage of query (165 bits)

TRPD_THETH / P83827 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Thermus thermophilus
TRPD_THET8 / Q5SH88 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
    44% identity, 75% coverage of query (163 bits)

CA265_RS05010 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Pedobacter sp. GW460-11-11-14-LB5
    30% identity, 86% coverage of query (151 bits)

Q9YGB4 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Thermococcus kodakarensis (see paper)
5nofA / Q9YGB4 Anthranilate phosphoribosyltransferase from thermococcus kodakaraensis (see paper)
    34% identity, 83% coverage of query (135 bits)

Build an alignment

Build an alignment for WP_011606228.1 and 38 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

1kgzB / Q8VP84 Crystal structure analysis of the anthranilate phosphoribosyltransferase from erwinia carotovora (current name, pectobacterium carotovorum) (see paper)
    28% identity, 91% coverage of query (133 bits)

BT0530 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Bacteroides thetaiotaomicron VPI-5482
    27% identity, 96% coverage of query (125 bits)

TRPD_YEAST / P07285 Anthranilate phosphoribosyltransferase; PRtransferase; EC 2.4.2.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    28% identity, 87% coverage of query (117 bits)

7dsjA / P07285 Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with prpp and mg (see paper)
    27% identity, 87% coverage of query (114 bits)

AN3634 anthranilate phosphoribosyltransferase, hypothetical (Eurofung) from Emericella nidulans (see paper)
    30% identity, 78% coverage of query (109 bits)

7dsoA Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with 4-fluoroanthranilate
    26% identity, 87% coverage of query (100 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory