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Searching for up to 100 curated homologs for WP_011606633.1 NCBI__GCF_000058485.1:WP_011606633.1 (484 a.a.)

Found high-coverage hits (≥70%) to 42 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

No hits had 30% identity

Change minimum %identity:

Additional hits (identity < 30%)

YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
    28% identity, 90% coverage of query (150 bits)

DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
    31% identity, 92% coverage of query (135 bits)

NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    22% identity, 89% coverage of query (134 bits)

YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
    27% identity, 91% coverage of query (134 bits)

AADAT / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (EC 2.6.1.7; EC 2.6.1.39) from Homo sapiens (see 5 papers)
AADAT_HUMAN / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Homo sapiens (Human) (see 4 papers)
Q8N5Z0 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Homo sapiens (see 16 papers)
    27% identity, 79% coverage of query (131 bits)

5tf5A Crystal structure of human kat-2 in complex with a reversible inhibitor
    27% identity, 79% coverage of query (131 bits)

2r2nA The crystal structure of human kynurenine aminotransferase ii in complex with kynurenine
    27% identity, 79% coverage of query (131 bits)

6t8qA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
    27% identity, 79% coverage of query (131 bits)

4gdyB / Q8N5Z0 Kynurenine aminotransferase ii inhibitors
    27% identity, 79% coverage of query (130 bits)

4gebA Kynurenine aminotransferase ii inhibitors
    27% identity, 79% coverage of query (130 bits)

4ge9A Kynurenine aminotransferase ii inhibitors
    27% identity, 79% coverage of query (130 bits)

4ge7A Kynurenine aminotransferase ii inhibitors
    27% identity, 79% coverage of query (130 bits)

YdcR / b1439 fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydcR / MB|P77730 uncharacterized HTH-type transcriptional regulator ydcR from Escherichia coli K12 (see 3 papers)
    27% identity, 91% coverage of query (129 bits)

8tn3A / Q643B9 Structure of s. Hygroscopicus aminotransferase mppq complexed with pyridoxamine 5'-phosphate (pmp) (see paper)
    35% identity, 73% coverage of query (128 bits)

4ge4A Kynurenine aminotransferase ii inhibitors
    27% identity, 79% coverage of query (127 bits)

LYSN_THET2 / Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
Q72LL6 2-aminoadipate transaminase (EC 2.6.1.39) from Thermus thermophilus (see paper)
2zyjA / Q72LL6 Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
    32% identity, 74% coverage of query (126 bits)

3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27
    32% identity, 74% coverage of query (126 bits)

2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
    32% identity, 74% coverage of query (126 bits)

2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
    32% identity, 74% coverage of query (126 bits)

lysN / Q5SL82 L-2-aminoadipate aminotransferase monomer (EC 2.6.1.39) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    32% identity, 74% coverage of query (125 bits)

Ac3H11_1015 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Acidovorax sp. GW101-3H11
    30% identity, 73% coverage of query (125 bits)

Desal_3745 / VIMSS8508801 Desal_3745 regulator of Metabolite transport from Desulfovibrio salexigens DSM 2638
    31% identity, 85% coverage of query (125 bits)

YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
    27% identity, 84% coverage of query (124 bits)

2zc0A / Q9C4M4 Crystal structure of an archaeal alanine:glyoxylate aminotransferase (see paper)
    27% identity, 72% coverage of query (121 bits)

DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
    23% identity, 90% coverage of query (117 bits)

DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
    27% identity, 90% coverage of query (117 bits)

DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
    26% identity, 86% coverage of query (109 bits)

YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
    25% identity, 90% coverage of query (103 bits)

DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
    27% identity, 87% coverage of query (103 bits)

DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
    26% identity, 87% coverage of query (100 bits)

PTSJ_SALTY / P40193 Vitamin B6 salvage pathway transcriptional repressor PtsJ; HTH-type transcriptional regulatory protein PtsJ from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    29% identity, 91% coverage of query (100 bits)

1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
    24% identity, 71% coverage of query (98.6 bits)

7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
    24% identity, 92% coverage of query (85.5 bits)

PdxR / VIMSS5804477 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus equi subsp. zooepidemicus MGCS10565
    23% identity, 78% coverage of query (85.1 bits)

PdxR / VIMSS101492 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus pyogenes M1 GAS
    21% identity, 82% coverage of query (83.6 bits)

PdxR / VIMSS10395811 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gallolyticus UCN34
    20% identity, 74% coverage of query (81.6 bits)

6uxzB (S)-4-amino-5-phenoxypentanoate as a selective agonist of the transcription factor gabr
    21% identity, 71% coverage of query (65.9 bits)

1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate
    30% identity, 74% coverage of query (63.9 bits)

1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
    30% identity, 74% coverage of query (63.9 bits)

5t4kA Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation
    21% identity, 71% coverage of query (62.4 bits)

5t4jB Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation
    21% identity, 71% coverage of query (62.4 bits)

2o1bA / Q2FV61 Structure of aminotransferase from staphylococcus aureus
    22% identity, 70% coverage of query (57.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory