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Searching for up to 100 curated homologs for WP_011607465.1 NCBI__GCF_000058485.1:WP_011607465.1 (476 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

sbnH / Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase (EC 4.1.1.117) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
SBNH_STAA8 / Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase; Staphyloferrin B biosynthesis protein SbnH; EC 4.1.1.117 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 2 papers)
Q2G1M6 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase (EC 4.1.1.117) from Staphylococcus aureus (see paper)
    31% identity, 90% coverage of query (217 bits)

6knhC / A0A0H3JPF2 Crystal structure of sbnh in complex with citrate, a plp-dependent decarboxylase in staphyloferrin b biothesynthesis (see paper)
    36% identity, 71% coverage of query (214 bits)

6knkA Crystal structure of sbnh in complex with citryl-diaminoethane
    35% identity, 71% coverage of query (209 bits)

6kniA Crystal structure of sbnh in complex with the cofactor plp, a plp- dependent decarboxylase in staphyloferrin b biothesynthesis
    35% identity, 71% coverage of query (206 bits)

Build an alignment

Build an alignment for WP_011607465.1 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

DCDA_HELPX / B4XMC6 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Helicobacter pylori (Campylobacter pylori) (see paper)
    29% identity, 71% coverage of query (123 bits)

P56129 diaminopimelate decarboxylase (EC 4.1.1.20) from Helicobacter pylori (see paper)
    29% identity, 71% coverage of query (118 bits)

Q9KVL7 diaminopimelate decarboxylase (EC 4.1.1.20) from Vibrio cholerae serotype O1 (see paper)
    29% identity, 70% coverage of query (107 bits)

1tufA / Q58497 Crystal structure of diaminopimelate decarboxylase from m. Jannaschi (see paper)
    26% identity, 70% coverage of query (105 bits)

DCDA_METJA / Q58497 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    26% identity, 70% coverage of query (105 bits)

1twiA Crystal structure of diaminopimelate decarboxylase from m. Jannaschii in co-complex with l-lysine
    26% identity, 70% coverage of query (105 bits)

BT1374 diaminopimelate decarboxylase (EC 4.1.1.20) from Bacteroides thetaiotaomicron VPI-5482
    26% identity, 71% coverage of query (99.4 bits)

4xg1B / A1SR00 Psychromonas ingrahamii diaminopimelate decarboxylase with llp
    26% identity, 70% coverage of query (94.0 bits)

Ga0059261_2051 diaminopimelate decarboxylase (EC 4.1.1.20) from Sphingomonas koreensis DSMZ 15582
    29% identity, 88% coverage of query (93.2 bits)

DCDA_THEMA / Q9X1K5 Diaminopimelate decarboxylase; DAP decarboxylase; DAPDC; EC 4.1.1.20 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
    27% identity, 71% coverage of query (91.3 bits)

2yxxA / Q9X1K5 Crystal structure analysis of diaminopimelate decarboxylate (lysa)
    27% identity, 71% coverage of query (91.3 bits)

4xg1A / A1SR00 Psychromonas ingrahamii diaminopimelate decarboxylase with llp
    25% identity, 70% coverage of query (89.7 bits)

AT3G14390 / Q949X7 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
DCDA1_ARATH / Q949X7 Diaminopimelate decarboxylase 1, chloroplastic; DAP decarboxylase 1; DAPDC 1; EC 4.1.1.20 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q949X7 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
    24% identity, 90% coverage of query (74.3 bits)

lysA / BAC66455.1 Diaminopimelate decarboxylase from Burkholderia multivorans (see paper)
    30% identity, 71% coverage of query (74.3 bits)

6n2aA / Q949X7 Meso-diaminopimelate decarboxylase from arabidopsis thaliana (isoform 1)
    24% identity, 90% coverage of query (74.3 bits)

AT5G11880 / Q94A94 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
DCDA2_ARATH / Q94A94 Diaminopimelate decarboxylase 2, chloroplastic; DAP decarboxylase 2; DAPDC 2; EC 4.1.1.20 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q94A94 diaminopimelate decarboxylase (EC 4.1.1.20) from Arabidopsis thaliana (see paper)
    24% identity, 90% coverage of query (73.6 bits)

ldc / O50657 L-lysine decarboxylase monomer (EC 4.1.1.18) from Selenomonas ruminantium (see paper)
ldc / BAC57940.1 lysine decarboxylase from Selenomonas ruminantium (see paper)
    25% identity, 73% coverage of query (46.6 bits)

O50657 Lysine/ornithine decarboxylase; LDC; EC 4.1.1.17; EC 4.1.1.18 from Selenomonas ruminantium
    25% identity, 73% coverage of query (46.6 bits)

5gjoA / O50657 Crystal structure of srldc mutant (a225c/t302c) in complex with plp (see paper)
    25% identity, 73% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory