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Searching for up to 100 curated homologs for WP_011610785.1 NCBI__GCF_000014265.1:WP_011610785.1 (377 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0A150JSL8 glycerol dehydrogenase (EC 1.1.1.6) from Weizmannia coagulans (see paper)
    32% identity, 93% coverage of query (201 bits)

4mcaA Crystal structure of glycerol dehydrogenase from serratia to 1.9a
    33% identity, 94% coverage of query (188 bits)

GLDA_THEMA / Q9WYQ4 Glycerol dehydrogenase; GDH; GLDH; EC 1.1.1.6 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYQ4 glycerol dehydrogenase (EC 1.1.1.6) from Thermotoga maritima (see 2 papers)
    33% identity, 90% coverage of query (184 bits)

1kq3A / Q9WYQ4 Crystal structure of a glycerol dehydrogenase (tm0423) from thermotoga maritima at 1.5 a resolution (see paper)
    33% identity, 90% coverage of query (184 bits)

GldA / b3945 L-1,2-propanediol dehydrogenase / glycerol dehydrogenase (EC 1.1.1.75; EC 1.1.1.6) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gldA / P0A9S5 L-1,2-propanediol dehydrogenase / glycerol dehydrogenase (EC 1.1.1.75; EC 1.1.1.6) from Escherichia coli (strain K12) (see 25 papers)
GLDA_ECOLI / P0A9S5 Glycerol dehydrogenase; GDH; GLDH; (R)-aminopropanol dehydrogenase; 1,2-propanediol dehydrogenase; D-1-amino-2-propanol oxidoreductase; EC 1.1.1.6; EC 1.1.1.75 from Escherichia coli (strain K12) (see 8 papers)
P0A9S5 glycerol dehydrogenase (EC 1.1.1.6) from Escherichia coli (see paper)
8goaA / P0A9S5 Crystal structure of glycerol dehydrogenase in the absence of NAD+ (see paper)
gldA / RF|NP_418380 glycerol dehydrogenase; EC 1.1.1.6 from Escherichia coli K12 (see 8 papers)
    34% identity, 92% coverage of query (179 bits)

A0MLR7 glycerol dehydrogenase (EC 1.1.1.6) from Klebsiella pneumoniae (see paper)
    34% identity, 92% coverage of query (179 bits)

Q8ZKM9 glycerol dehydrogenase (EC 1.1.1.6) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    33% identity, 92% coverage of query (179 bits)

8gobA Crystal structure of glycerol dehydrogenase in the presence of NAD+
    34% identity, 92% coverage of query (179 bits)

5zxlA Structure of glda from e.Coli
    34% identity, 92% coverage of query (179 bits)

A6TGD6 glycerol dehydrogenase (EC 1.1.1.6) from Klebsiella pneumoniae subsp. pneumoniae (see paper)
8k1gA / A6TGD6 Crystal structure of ethylene glycol-bound glycerol dehydrogenase from klebsiella pneumoniae
    34% identity, 92% coverage of query (177 bits)

B2ZPN8 glycerol dehydrogenase (EC 1.1.1.6) from Klebsiella pneumoniae (see 3 papers)
    34% identity, 92% coverage of query (177 bits)

8k1hA Crystal structure of ethylene glycol-bound glycerol dehydrogenase from klebsiella pneumoniae
    34% identity, 92% coverage of query (177 bits)

GLDA_CITFR / P45511 Glycerol dehydrogenase; GDH; GLDH; EC 1.1.1.6 from Citrobacter freundii (see paper)
dhaD / GB|AAB48844.1 glycerol dehydrogenase; EC 1.1.1.6 from Citrobacter freundii (see paper)
dhaD / AAB48844.1 glycerol dehydrogenase from Citrobacter freundii (see 4 papers)
    31% identity, 94% coverage of query (174 bits)

bedD / GB|AAC44426.1 glycerol dehydrogenase; EC 1.1.1.6 from Pseudomonas putida (see paper)
gldA / AAC44426.1 GldA from Pseudomonas putida (see 3 papers)
    33% identity, 92% coverage of query (172 bits)

A0A1D3TV18 glycerol dehydrogenase (EC 1.1.1.6) from Anaerobium acetethylicum (see paper)
    31% identity, 89% coverage of query (167 bits)

HcxA / b0599 hydroxycarboxylate dehydrogenase A from Escherichia coli K-12 substr. MG1655 (see 4 papers)
HCXA_ECOLI / P45579 Hydroxycarboxylate dehydrogenase A; 2-oxobutanoate reductase; 2-oxoglutarate reductase; EC 1.1.1.- from Escherichia coli (strain K12) (see paper)
    38% identity, 76% coverage of query (162 bits)

Build an alignment

Build an alignment for WP_011610785.1 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

A0A0H3J8E1 glycerol dehydrogenase (EC 1.1.1.6) from Clostridium pasteurianum (see paper)
    28% identity, 93% coverage of query (161 bits)

Q9HHR2 glycolaldehyde reductase (EC 1.1.1.77) from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (see paper)
GLYAR_HALSA / Q9HHR2 Glycolaldehyde reductase; GaR; EC 1.1.1.- from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
    29% identity, 94% coverage of query (158 bits)

GLDA_GEOSE / P32816 Glycerol dehydrogenase; GDH; GLDH; GlyDH; EC 1.1.1.6 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P32816 glycerol dehydrogenase (EC 1.1.1.6) from Geobacillus stearothermophilus (see paper)
gldA / GI|142978 glycerol dehydrogenase; EC 1.1.1.6 from Geobacillus stearothermophilus (see 4 papers)
    31% identity, 93% coverage of query (157 bits)

1jq5A / P32816 Bacillus stearothermophilus glycerol dehydrogenase complex with NAD+ (see paper)
    31% identity, 93% coverage of query (157 bits)

1ta9B / O13702 Crystal structure of glycerol dehydrogenase from schizosaccharomyces pombe
    32% identity, 92% coverage of query (154 bits)

5xn8A Structure of glycerol dehydrogenase crystallised as a contaminant
    30% identity, 94% coverage of query (154 bits)

3uhjA / Q92MR2 Crystal structure of a probable glycerol dehydrogenase from sinorhizobium meliloti 1021
    32% identity, 77% coverage of query (154 bits)

GLD1_SCHPO / O13702 Glycerol dehydrogenase 1; GDH; GLDH; EC 1.1.1.6 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
O13702 glycerol dehydrogenase (EC 1.1.1.6) from Schizosaccharomyces pombe (see paper)
gld1 / RF|NP_593651.1 mitochondrial glycerol dehydrogenase Gld1 from Schizosaccharomyces pombe (see 2 papers)
    32% identity, 92% coverage of query (154 bits)

1jqaA Bacillus stearothermophilus glycerol dehydrogenase complex with glycerol
    31% identity, 93% coverage of query (147 bits)

bdhB / Q04945 BdhB from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see 5 papers)
    23% identity, 83% coverage of query (55.8 bits)

6jkoA / A0A0A7I0A5 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense (see paper)
    22% identity, 77% coverage of query (55.5 bits)

6jkpA Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+
    22% identity, 77% coverage of query (55.5 bits)

bdhA / Q04944 BdhA from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see 2 papers)
bdhA / GI|15026377 NADH-dependent butanol dehydrogenase A from Clostridium acetobutylicum ATCC 824 (see paper)
bdhA NADH-dependent butanol dehydrogenase A; EC 1.1.1.- from Clostridium acetobutylicum (see paper)
    22% identity, 84% coverage of query (50.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory