Searching for up to 100 curated homologs for WP_011613632.1 NCBI__GCF_000014265.1:WP_011613632.1 (428 a.a.)
Found high-coverage hits (≥70%) to 97 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
O74024 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus profundus (see 2 papers)
8xd5A / O74024 Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADP and glu in the steady stage of reaction (see paper)
53% identity, 97% coverage of query (426 bits)
8xcsA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADPH, akg and nh4 in the initial stage of reaction
53% identity, 97% coverage of query (426 bits)
8xcoA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus incorporating NADPH in the initial stage of reaction
53% identity, 97% coverage of query (426 bits)
gdhA / GB|AAA64795.1 glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Pyrococcus endeavori (see paper)
52% identity, 97% coverage of query (422 bits)
8zneA Cryo-em structure of w89f mutated glutamate dehydrogenase from thermococcus profundus in complex with NADP and glu in the steady stage of reaction
53% identity, 97% coverage of query (421 bits)
P80319 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Pyrococcus furiosus (see 6 papers)
52% identity, 96% coverage of query (416 bits)
DHE3_THELN / Q56304 Glutamate dehydrogenase; GDH; EC 1.4.1.3 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 2 papers)
Q56304 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3); glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus litoralis (see 5 papers)
50% identity, 97% coverage of query (414 bits)
DHE2_BACSU / P39633 Catabolic NAD-specific glutamate dehydrogenase RocG; NAD-GDH; Glutamate dehydrogenase; GlutDH; Trigger enzyme RocG; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 7 papers)
49% identity, 97% coverage of query (414 bits)
P96110 trimer complex (EC 1.4.1.2) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
P96110 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermotoga maritima (see paper)
gdhA glutamate dehydrogenase; EC 1.4.1.3 from Thermotoga maritima (see 2 papers)
50% identity, 97% coverage of query (404 bits)
DHE3_THEKO / O59650 Glutamate dehydrogenase; GDH; EC 1.4.1.3 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
O59650 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus kodakarensis (see 2 papers)
gdhA glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Thermococcus kodakarensis (see paper)
51% identity, 97% coverage of query (402 bits)
Q977X9 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus waiotapuensis (see paper)
52% identity, 97% coverage of query (400 bits)
GUDB_BACSU / P50735 Cryptic catabolic NAD-specific glutamate dehydrogenase GudB; NAD-GDH; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 3 papers)
48% identity, 95% coverage of query (397 bits)
Q0E5I0 glutamate dehydrogenase (EC 1.4.1.2) from Halobacillus halophilus (see paper)
47% identity, 95% coverage of query (394 bits)
gdhB / P29051 GdhA (EC 1.4.1.4) from Halobacterium salinarum (see 3 papers)
DHE2_HALSI / P29051 NAD-specific glutamate dehydrogenase A; NAD-GDH A; EC 1.4.1.2 from Halobacterium salinarum (Halobacterium halobium) (see 2 papers)
P29051 glutamate dehydrogenase (EC 1.4.1.2) from Halobacterium salinarum (see 2 papers)
gdhA / GB|AAW19068.1 glutamate dehydrogenase; EC 1.4.1.2 from Halobacterium salinarum (see paper)
47% identity, 98% coverage of query (391 bits)
Q977U6 glutamate dehydrogenase (EC 1.4.1.2) from Haloferax mediterranei (see paper)
46% identity, 98% coverage of query (360 bits)
O04937 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Nicotiana plumbaginifolia (see paper)
43% identity, 97% coverage of query (356 bits)
4xgiA / Q2SZ78 Crystal structure of glutamate dehydrogenase from burkholderia thailandensis
44% identity, 97% coverage of query (355 bits)
Q9S7A0 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see paper)
45% identity, 96% coverage of query (354 bits)
DHE4_HALSI / Q5MBG2 NADP-specific glutamate dehydrogenase A1; EC 1.4.1.4 from Halobacterium salinarum (Halobacterium halobium) (see paper)
42% identity, 97% coverage of query (350 bits)
P27346 glutamate dehydrogenase (EC 1.4.1.2) from Clostridioides difficile (see paper)
gluD / GB|AAA62756.1 NAD-specific glutamate dehydrogenase; EC 1.4.1.2 from Clostridium difficile (see paper)
46% identity, 97% coverage of query (348 bits)
3aoeB / Q72IC1 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
45% identity, 97% coverage of query (348 bits)
Q9LEC8 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Nicotiana plumbaginifolia (see 2 papers)
44% identity, 97% coverage of query (348 bits)
3aogA Crystal structure of glutamate dehydrogenase (gdhb) from thermus thermophilus (glu bound form)
45% identity, 97% coverage of query (348 bits)
DHE3_ORYSJ / Q6H3Y7 Glutamate dehydrogenase 3, mitochondrial; OsGDH3; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
42% identity, 97% coverage of query (347 bits)
Q5QDM6 glutamate dehydrogenase (EC 1.4.1.2) from Lupinus luteus (see paper)
43% identity, 97% coverage of query (346 bits)
8owmC / Q38946 Crystal structure of glutamate dehydrogenase 2 from arabidopsis thaliana binding ca, NAD and 2,2-dihydroxyglutarate (see paper)
43% identity, 97% coverage of query (346 bits)
GDH2 / Q38946 glutamate dehydrogenase β subunit (EC 1.4.1.2) from Arabidopsis thaliana (see 4 papers)
DHE2_ARATH / Q38946 Glutamate dehydrogenase 2; GDH 2; EC 1.4.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q38946 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see paper)
43% identity, 97% coverage of query (346 bits)
Q43314 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see 2 papers)
43% identity, 96% coverage of query (343 bits)
6yehA / Q43314 Arabidopsis thaliana glutamate dehydrogenase isoform 1 in apo form (see paper)
43% identity, 96% coverage of query (342 bits)
6yeiF Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
43% identity, 96% coverage of query (342 bits)
6yeiA Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
43% identity, 96% coverage of query (342 bits)
DHE2_ORYSJ / Q33E23 Glutamate dehydrogenase 2, mitochondrial; OsGDH2; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 7 papers)
42% identity, 97% coverage of query (339 bits)
DHE1_ORYSJ / Q852M0 Glutamate dehydrogenase 1, mitochondrial; OsGDH1; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q852M0 glutamate dehydrogenase (EC 1.4.1.2) from Oryza sativa (see paper)
42% identity, 97% coverage of query (336 bits)
DHE2_PYRCJ / A3MUY9 NAD(+)-dependent glutamate dehydrogenase; NAD-GDH; NAD-specific glutamate dehydrogenase; EC 1.4.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUY9 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum calidifontis (see paper)
43% identity, 95% coverage of query (335 bits)
GDH1 / P93541 glutamate dehydrogenase (EC 1.4.1.3) from Solanum lycopersicum (see paper)
P93541 glutamate dehydrogenase (EC 1.4.1.2) from Solanum lycopersicum (see paper)
44% identity, 97% coverage of query (333 bits)
gdhA / P28997 NAD-glutamate dehydrogenase subunit (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see paper)
DHE2_PEPAS / P28997 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Peptoniphilus asaccharolyticus (Peptostreptococcus asaccharolyticus) (see 2 papers)
P28997 glutamate dehydrogenase (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see 2 papers)
41% identity, 98% coverage of query (331 bits)
Q9YC65 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aeropyrum pernix (see paper)
43% identity, 97% coverage of query (329 bits)
P80053 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Saccharolobus solfataricus (see paper)
41% identity, 98% coverage of query (319 bits)
P80053 Glutamate dehydrogenase 2; GDH-2; EC 1.4.1.3 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
41% identity, 98% coverage of query (319 bits)
DHE4_PYRCJ / A3MWK6 NADP(+)-dependent glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MWK6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Pyrobaculum calidifontis (see paper)
42% identity, 95% coverage of query (316 bits)
1v9lA / Q9Y8I4 L-glutamate dehydrogenase from pyrobaculum islandicum complexed with NAD (see paper)
43% identity, 95% coverage of query (313 bits)
Q9Y8I4 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum islandicum (see paper)
43% identity, 95% coverage of query (313 bits)
8karA / A0A0E3K1C8 Glutamate dehydrogenase-akg
41% identity, 98% coverage of query (312 bits)
8kaoC Glutamate dehydrogenase-69o
42% identity, 96% coverage of query (311 bits)
Q93IM2 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermus thermophilus (see paper)
37% identity, 98% coverage of query (282 bits)
3aoeF / Q72IC0 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
36% identity, 98% coverage of query (281 bits)
DHE3_DICDI / Q54KB7 Glutamate dehydrogenase, mitochondrial; GDH; EC 1.4.1.3 from Dictyostelium discoideum (Social amoeba) (see 2 papers)
39% identity, 96% coverage of query (279 bits)
6dhdA / P00366 Bovine glutamate dehydrogenase complexed with nadh, gtp, glutamate (see paper)
41% identity, 85% coverage of query (271 bits)
6dhlA Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ecg)
41% identity, 85% coverage of query (271 bits)
8ar7A Bovine glutamate dehydrogenase in ternary complex with the allosteric activators adp and leucine
41% identity, 85% coverage of query (271 bits)
3etgA Glutamate dehydrogenase complexed with gw5074
41% identity, 85% coverage of query (271 bits)
3etdA Structure of glutamate dehydrogenase complexed with bithionol
41% identity, 85% coverage of query (271 bits)
3eteA Crystal structure of bovine glutamate dehydrogenase complexed with hexachlorophene
41% identity, 85% coverage of query (271 bits)
6dhmA Bovine glutamate dehydrogenase complexed with zinc
41% identity, 85% coverage of query (271 bits)
GLUD2 / P49448 Glutamate dehydrogenase 2, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE4_HUMAN / P49448 Glutamate dehydrogenase 2, mitochondrial; GDH 2; EC 1.4.1.3 from Homo sapiens (Human) (see paper)
P49448 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 6 papers)
44% identity, 76% coverage of query (269 bits)
DHE3_MOUSE / P26443 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Mus musculus (Mouse) (see 3 papers)
P26443 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Mus musculus (see 2 papers)
44% identity, 76% coverage of query (266 bits)
DHE3_BOVIN / P00366 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Bos taurus (Bovine) (see 4 papers)
P00366 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Bos taurus (see 3 papers)
40% identity, 85% coverage of query (266 bits)
DHE3_PIG / P42174 Glutamate dehydrogenase 1, mitochondrial; GDH 1; Membrane protein 50; MP50; EC 1.4.1.3 from Sus scrofa (Pig) (see paper)
44% identity, 76% coverage of query (266 bits)
DHE3_RAT / P10860 Glutamate dehydrogenase 1, mitochondrial; GDH 1; Memory-related gene 2 protein; MRG-2; EC 1.4.1.3 from Rattus norvegicus (Rat) (see paper)
P10860 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Rattus norvegicus (see 3 papers)
44% identity, 76% coverage of query (266 bits)
GLUD1 / P00367 Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE3_HUMAN / P00367 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Homo sapiens (Human) (see 10 papers)
P00367 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 8 papers)
44% identity, 76% coverage of query (266 bits)
1nqtA Crystal structure of bovine glutamate dehydrogenase-adp complex
43% identity, 76% coverage of query (265 bits)
DHE3_DROME / P54385 Glutamate dehydrogenase, mitochondrial; GDH; EC 1.4.1.3 from Drosophila melanogaster (Fruit fly) (see paper)
40% identity, 84% coverage of query (262 bits)
1hwyA Bovine glutamate dehydrogenase complexed with NAD and 2-oxoglutarate
43% identity, 76% coverage of query (261 bits)
Q0E5H9 glutamate dehydrogenase (EC 1.4.1.2) from Halobacillus halophilus (see paper)
37% identity, 88% coverage of query (250 bits)
A0A1V1FMC4 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Streptococcus equinus (see paper)
33% identity, 93% coverage of query (201 bits)
DHE4_XYLRU / P95544 NAD(P)-specific glutamate dehydrogenase; NAD(P)-GDH; NAD(P)H-dependent glutamate dehydrogenase; EC 1.4.1.3 from Xylanibacter ruminicola (Prevotella ruminicola) (see paper)
32% identity, 93% coverage of query (195 bits)
P28724 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Giardia intestinalis (see paper)
32% identity, 86% coverage of query (193 bits)
1bgvA / P24295 Glutamate dehydrogenase (see paper)
33% identity, 92% coverage of query (192 bits)
DHE2_CLOSY / P24295 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Clostridium symbiosum (Bacteroides symbiosus) (see 4 papers)
P24295 glutamate dehydrogenase (EC 1.4.1.2) from [Clostridium] symbiosum (see 4 papers)
gdh / CAA77805.1 Glutamate Dehydrogenase from [Clostridium] symbiosum (see paper)
33% identity, 92% coverage of query (192 bits)
A0A1D8PMH8 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Candida albicans (see 2 papers)
33% identity, 94% coverage of query (185 bits)
A0A0U4QBJ6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
32% identity, 92% coverage of query (185 bits)
7f79C / A0A1D8PMH8 Crystal structure of glutamate dehydrogenase 3 from candida albicans in complex with alpha-ketoglutarate and NADPH (see paper)
34% identity, 94% coverage of query (185 bits)
5gudE Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex) (see paper)
31% identity, 92% coverage of query (185 bits)
P31026 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
32% identity, 92% coverage of query (185 bits)
5gudA Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex)
31% identity, 92% coverage of query (185 bits)
5ijzA Crystal structure of glutamate dehydrogenase(gdh) from corynebacterium glutamicum
32% identity, 92% coverage of query (185 bits)
Q8ILF7 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Plasmodium falciparum (see paper)
30% identity, 86% coverage of query (179 bits)
DHE4_PSYT1 / Q9S1F9 NADP-specific glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Psychrobacter sp. (strain TAD1) (see paper)
32% identity, 92% coverage of query (176 bits)
A0R3E3 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Mycolicibacterium smegmatis (see paper)
31% identity, 83% coverage of query (169 bits)
5xvvB / B6V7E4 Crystal structure of forward inhibited aspergillus niger glutamate dehydrogenase with both apo- and alpha ketoglutarate bound subunits (see paper)
31% identity, 97% coverage of query (167 bits)
B6V7E4 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aspergillus niger (see paper)
31% identity, 97% coverage of query (167 bits)
5xwcA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-iminoglutarate, 2-amino-2-hydroxyglutarate and NADP
31% identity, 97% coverage of query (167 bits)
5xw0A Crystal structure of aspergillus niger glutamate dehydrogenase complexed with isophthalate and NADPH
31% identity, 97% coverage of query (167 bits)
5xvxA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-ketoglutarate and NADPH
31% identity, 97% coverage of query (167 bits)
GdhA / b1761 glutamate dehydrogenase (EC 1.4.1.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
gdhA / P00370 glutamate dehydrogenase (EC 1.4.1.4) from Escherichia coli (strain K12) (see 38 papers)
DHE4_ECOLI / P00370 NADP-specific glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Escherichia coli (strain K12) (see 2 papers)
P00370 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Escherichia coli (see 3 papers)
30% identity, 87% coverage of query (163 bits)
7ecsA Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with malonate and NADPH
30% identity, 97% coverage of query (163 bits)
7ecrA / T2D1F5 Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with succinate and adp-ribose (see paper)
30% identity, 97% coverage of query (163 bits)
P78804 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
31% identity, 84% coverage of query (159 bits)
P00369 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
31% identity, 89% coverage of query (155 bits)
Build an alignment for WP_011613632.1 and 89 homologs with ≥ 30% identity
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DHPH_BACBA / Q59224 Phenylalanine dehydrogenase; PheDH; EC 1.4.1.20 from Bacillus badius (see paper)
Q59224 phenylalanine dehydrogenase (EC 1.4.1.20) from Bacillus badius (see paper)
26% identity, 77% coverage of query (89.7 bits)
1c1dA L-phenylalanine dehydrogenase structure in ternary complex with nadh and l-phenylalanine
25% identity, 82% coverage of query (74.3 bits)
1c1xA L-phenylalanine dehydrogenase structure in ternary complex with NAD+ and l-3-phenyllactate
25% identity, 82% coverage of query (74.3 bits)
1bw9A / Q59771 Phenylalanine dehydrogenase structure in ternary complex with NAD+ and phenylpyruvate (see paper)
25% identity, 82% coverage of query (74.3 bits)
1bxgA Phenylalanine dehydrogenase structure in ternary complex with NAD+ and beta-phenylpropionate
25% identity, 82% coverage of query (72.4 bits)
DHPH_RHOSO / Q59771 Phenylalanine dehydrogenase; PheDH; EC 1.4.1.20 from Rhodococcus sp. (see 2 papers)
pdh / AAA21461.1 L-phenylalanine dehydrogenase precursor from Rhodococcus sp (see paper)
25% identity, 82% coverage of query (72.4 bits)
TRPDH_NOSPU / W8CV45 L-tryptophan dehydrogenase; L-Trp dehydrogenase; TrpDH; NpTrpDH; EC 1.4.1.19 from Nostoc punctiforme (see 2 papers)
W8CV45 tryptophan dehydrogenase (EC 1.4.1.19) from Nostoc punctiforme (see 2 papers)
24% identity, 84% coverage of query (72.0 bits)
TRPDH_NOSP7 / B2IXH4 L-tryptophan dehydrogenase; L-Trp dehydrogenase; TrpDH; EC 1.4.1.19 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see 2 papers)
25% identity, 84% coverage of query (69.7 bits)
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