Searching for up to 100 curated homologs for WP_011650166.1 NCBI__GCF_000009265.1:WP_011650166.1 (553 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7nedA / A0A0Q9KFZ4 Thiourocanate hydratase from paenibacillus sp. Soil724d2 in complex with cofactor NAD+ and urocanate (see paper)
    67% identity, 97% coverage of query (750 bits)

HUTU_GEOKA / Q5L084 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Geobacillus kaustophilus (strain HTA426)
    52% identity, 97% coverage of query (561 bits)

Ga0059261_3961 Urocanate hydratase (EC 4.2.1.49) from Sphingomonas koreensis DSMZ 15582
    53% identity, 97% coverage of query (548 bits)

PS417_01720 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas simiae WCS417
    50% identity, 97% coverage of query (540 bits)

7jfzA / Q5ZVR1 Structure of urocanate hydratase from legionella pneumophila bound to NAD
    50% identity, 97% coverage of query (537 bits)

1uwkA / P25080 The high resolution structure of urocanate hydratase from pseudomonas putida in complex with urocanate (see paper)
    50% identity, 97% coverage of query (536 bits)

hutU / P25080 urocanase subunit (EC 4.2.1.49) from Pseudomonas putida (see 4 papers)
HUTU_PSEPU / P25080 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
    49% identity, 97% coverage of query (534 bits)

AO353_12250 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2E3
    50% identity, 95% coverage of query (534 bits)

AO356_09630 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2C3
    50% identity, 95% coverage of query (532 bits)

Pf6N2E2_3805 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2E2
    50% identity, 95% coverage of query (531 bits)

hutU / P25503 HutU (EC 4.2.1.49) from Bacillus subtilis (strain 168) (see 2 papers)
HUTU_BACSU / P25503 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Bacillus subtilis (strain 168) (see paper)
    50% identity, 96% coverage of query (529 bits)

Pf1N1B4_1587 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N1B4
    50% identity, 95% coverage of query (529 bits)

2fknB / P25503 Crystal structure of urocanase from bacillus subtilis
    50% identity, 96% coverage of query (529 bits)

PfGW456L13_326 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens GW456-L13
    49% identity, 95% coverage of query (528 bits)

SM_b21163 Urocanate hydratase (EC 4.2.1.49) from Sinorhizobium meliloti 1021
    50% identity, 98% coverage of query (526 bits)

BWI76_RS08735 Urocanate hydratase (EC 4.2.1.49) from Klebsiella michiganensis M5al
    49% identity, 98% coverage of query (523 bits)

Ac3H11_2557 Urocanate hydratase (EC 4.2.1.49) from Acidovorax sp. GW101-3H11
    48% identity, 98% coverage of query (521 bits)

PGA1_c36320 Urocanate hydratase (EC 4.2.1.49) from Phaeobacter inhibens BS107
    49% identity, 97% coverage of query (505 bits)

8q9vA / A0A6P2DXK2 S-methylthiourocanate hydratase from variovorax sp. Ra8 in complex with NAD+ and imidazolone propionate (see paper)
    50% identity, 95% coverage of query (489 bits)

1x87A / Q5L084 2.4a x-ray structure of urocanase protein complexed with NAD
    47% identity, 97% coverage of query (467 bits)

Sama_1632 Urocanate hydratase (EC 4.2.1.49) from Shewanella amazonensis SB2B
    31% identity, 94% coverage of query (250 bits)

6uekA / Q4D9S6 Structure of urocanate hydratase from trypanosoma cruzi in complex with NAD+ (see paper)
    33% identity, 89% coverage of query (245 bits)

Build an alignment

Build an alignment for WP_011650166.1 and 22 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

HUTU_HUMAN / Q96N76 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Homo sapiens (Human) (see paper)
    29% identity, 93% coverage of query (228 bits)

6uekD / Q4D9S6 Structure of urocanate hydratase from trypanosoma cruzi in complex with NAD+ (see paper)
    32% identity, 91% coverage of query (213 bits)

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