Searching for up to 100 curated homologs for WP_011650388.1 NCBI__GCF_000009265.1:WP_011650388.1 (354 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

C3KM96 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Sinorhizobium fredii (see paper)
    61% identity, 91% coverage of query (345 bits)

Hibch / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Rattus norvegicus (see 5 papers)
HIBCH_RAT / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Rattus norvegicus (Rat) (see 2 papers)
    43% identity, 95% coverage of query (264 bits)

PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas simiae WCS417
    43% identity, 96% coverage of query (263 bits)

Pf1N1B4_4790 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N1B4
    41% identity, 98% coverage of query (259 bits)

PfGW456L13_2986 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens GW456-L13
    41% identity, 96% coverage of query (253 bits)

HIBCH_HUMAN / Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Homo sapiens (Human) (see 2 papers)
    40% identity, 96% coverage of query (252 bits)

3bptA / Q6NVY1 Crystal structure of human beta-hydroxyisobutyryl-coa hydrolase in complex with quercetin
    40% identity, 96% coverage of query (249 bits)

AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N2E3
    40% identity, 95% coverage of query (243 bits)

bch / Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (see paper)
    38% identity, 93% coverage of query (243 bits)

Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas stutzeri RCH2
    41% identity, 95% coverage of query (238 bits)

echA9 / O53419 steroid enoyl-CoA hydratase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    40% identity, 98% coverage of query (231 bits)

RR42_RS28545 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Cupriavidus basilensis FW507-4G11
    40% identity, 98% coverage of query (231 bits)

4hdtA / G7CC99 Crystal structure of a carnitinyl-coa dehydratase from mycobacterium thermoresistibile (see paper)
    40% identity, 98% coverage of query (229 bits)

HIBC1_ARATH / Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase 1; CoA-thioester hydrolase CHY1; EC 3.1.2.-; EC 3.1.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Arabidopsis thaliana (see paper)
    38% identity, 97% coverage of query (226 bits)

HIBCH_NEUCR / Q1K7A4 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
    38% identity, 99% coverage of query (224 bits)

PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Phaeobacter inhibens BS107
    39% identity, 96% coverage of query (202 bits)

EHD3 / Q5AI24 3-hydroxypropanonyl-CoA hydrolase (EC 3.1.2.4) from Candida albicans (strain SC5314 / ATCC MYA-2876) (see paper)
    32% identity, 95% coverage of query (199 bits)

Q9SE41 enoyl-CoA hydratase (EC 4.2.1.17) from Avicennia marina (see paper)
    35% identity, 85% coverage of query (193 bits)

HIBCH_YEAST / P28817 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
    32% identity, 96% coverage of query (169 bits)

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Build an alignment for WP_011650388.1 and 19 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ECH19_MYCTU / O53561 Enoyl-CoA hydratase EchA19; EC 4.2.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 5 papers)
    27% identity, 72% coverage of query (58.2 bits)

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