Searching for up to 100 curated homologs for WP_011651695.1 NCBI__GCF_000023185.1:WP_011651695.1 (145 a.a.)
Found high-coverage hits (≥70%) to 79 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
D4LCT8 3-dehydroquinate dehydratase (EC 4.2.1.10) from Ruminococcus champanellensis (see paper)
59% identity, 94% coverage of query (162 bits)
G8M0G7 3-dehydroquinate dehydratase (EC 4.2.1.10) from Acetivibrio clariflavus (see paper)
53% identity, 94% coverage of query (158 bits)
W6JLW3 3-dehydroquinate dehydratase (EC 4.2.1.10) from Gluconobacter oxydans (see paper)
55% identity, 96% coverage of query (157 bits)
GOX0437 / Q5FTS6 periplasmic dehydroquinate dehydratase (EC 4.2.1.10) from Gluconobacter oxydans (strain 621H) (see 2 papers)
54% identity, 96% coverage of query (157 bits)
E4RLB7 3-dehydroquinate dehydratase (EC 4.2.1.10) from Halanaerobium hydrogeniformans (see paper)
52% identity, 97% coverage of query (153 bits)
AROQ_BACSU / P54517 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 from Bacillus subtilis (strain 168)
P54517 3-dehydroquinate dehydratase (EC 4.2.1.10) from Bacillus subtilis (see paper)
51% identity, 94% coverage of query (152 bits)
AROQ_ACTPL / P43877 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 from Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae) (see paper)
52% identity, 93% coverage of query (151 bits)
D1A7X0 3-dehydroquinate dehydratase (EC 4.2.1.10) from Thermomonospora curvata (see paper)
49% identity, 97% coverage of query (151 bits)
M1E6S9 3-dehydroquinate dehydratase (EC 4.2.1.10) from Thermodesulfobium narugense (see paper)
54% identity, 95% coverage of query (150 bits)
A0A124C1Y7 3-dehydroquinate dehydratase (EC 4.2.1.10) from Streptomyces acidiscabies (see paper)
54% identity, 92% coverage of query (150 bits)
AROQ_STRCO / P15474 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 3 papers)
P15474 3-dehydroquinate dehydratase (EC 4.2.1.10) from Streptomyces coelicolor (see 5 papers)
aroQ / CAA04787.1 dehydroquinate dehydratase from Streptomyces coelicolor (see 2 papers)
53% identity, 92% coverage of query (148 bits)
1v1jA / P15474 Crystal structure of type ii dehydroquintae dehydratase from streptomyces coelicolor in complex with 3-fluoro (see paper)
53% identity, 92% coverage of query (148 bits)
2cjfA Type ii dehydroquinase inhibitor complex
53% identity, 92% coverage of query (148 bits)
2bt4A Type ii dehydroquinase inhibitor complex
53% identity, 92% coverage of query (148 bits)
1gu1A Crystal structure of type ii dehydroquinase from streptomyces coelicolor complexed with 2,3-anhydro-quinic acid
53% identity, 92% coverage of query (148 bits)
O52377 3-dehydroquinate dehydratase (EC 4.2.1.10) from Corynebacterium glutamicum (see paper)
53% identity, 99% coverage of query (145 bits)
qsuC / A4QB64 3-dehydroquinate dehydratase (EC 4.2.1.10) from Corynebacterium glutamicum (strain R) (see paper)
53% identity, 99% coverage of query (145 bits)
N1V364 3-dehydroquinate dehydratase (EC 4.2.1.10) from Arthrobacter crystallopoietes (see paper)
52% identity, 97% coverage of query (145 bits)
I0L192 3-dehydroquinate dehydratase (EC 4.2.1.10) from Micromonospora lupini (see paper)
49% identity, 94% coverage of query (145 bits)
1gtzA Structure of streptomyces coelicolor type ii dehydroquinase r23a mutant in complex with dehydroshikimate
52% identity, 92% coverage of query (145 bits)
3DHQ_EMENI / P05147 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; EC 4.2.1.10 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
qutE / GI|2404 catabolic 3-dehydroquinase from Emericella nidulans (see 3 papers)
50% identity, 94% coverage of query (144 bits)
8idrC / O52377 Crystal structure of apo-form of dehydroquinate dehydratase from corynebacterium glutamicum (see paper)
54% identity, 96% coverage of query (144 bits)
AROQ_MYCTU / P9WPX7 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WPX7 3-dehydroquinate dehydratase (EC 4.2.1.10) from Mycobacterium tuberculosis (see 10 papers)
51% identity, 97% coverage of query (142 bits)
3n8kM / P9WPX7 Type ii dehydroquinase from mycobacterium tuberculosis complexed with citrazinic acid (see paper)
51% identity, 97% coverage of query (142 bits)
8iduA Crystal structure of substrate bound-form dehydroquinate dehydratase from corynebacterium glutamicum
53% identity, 96% coverage of query (142 bits)
4cl0A Structure of the mycobacterium tuberculosis type ii dehydroquinase inhibited by a 3-dehydroquinic acid derivative
51% identity, 94% coverage of query (141 bits)
4b6pA Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2s)-2-perfluorobenzyl-3-dehydroquinic acid
51% identity, 94% coverage of query (141 bits)
3n76A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with compound 5
51% identity, 94% coverage of query (141 bits)
4b6oA Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2s)-2-(4-methoxy)benzyl-3-dehydroquinic acid
51% identity, 94% coverage of query (141 bits)
3n59C Type ii dehydroquinase from mycobacterium tuberculosis complexed with 3-dehydroshikimate
51% identity, 94% coverage of query (141 bits)
4kiwA Design and structural analysis of aromatic inhibitors of type ii dehydroquinate dehydratase from mycobacterium tuberculosis - compound 49e [5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid]
51% identity, 94% coverage of query (141 bits)
4kiuA Design and structural analysis of aromatic inhibitors of type ii dehydroquinate dehydratase from mycobacterium tuberculosis - compound 49d [5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid]
51% identity, 94% coverage of query (141 bits)
4ciwA Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-(2-hydroxy) ethylcyclohex-2-ene-1-carboxylic acid
51% identity, 94% coverage of query (141 bits)
3n87A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 3
51% identity, 94% coverage of query (141 bits)
3n86A Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 4
51% identity, 94% coverage of query (141 bits)
2xb8A Structure of mycobacterium tuberculosis type ii dehydroquinase in complex with inhibitor compound (2r)-2-(4-methoxybenzyl)-3- dehydroquinic acid
51% identity, 94% coverage of query (141 bits)
4kijA Design and structural analysis of aromatic inhibitors of type ii dehydroquinase dehydratase from mycobacterium tuberculosis - compound 35c [3,4-dihydroxy-5-(3-nitrophenoxy)benzoic acid]
51% identity, 94% coverage of query (139 bits)
Q88IJ6 3-dehydroquinate dehydratase (EC 4.2.1.10) from Pseudomonas putida (see paper)
49% identity, 96% coverage of query (138 bits)
A1SZA3 3-dehydroquinate dehydratase (EC 4.2.1.10) from Psychromonas ingrahamii (see paper)
50% identity, 99% coverage of query (138 bits)
A0A0H3FM50 3-dehydroquinate dehydratase (EC 4.2.1.10) from Klebsiella aerogenes (see paper)
49% identity, 97% coverage of query (137 bits)
A3M692 3-dehydroquinate dehydratase (EC 4.2.1.10) from Acinetobacter baumannii (see paper)
49% identity, 94% coverage of query (137 bits)
A8AQF2 3-dehydroquinate dehydratase (EC 4.2.1.10) from Citrobacter koseri (see paper)
49% identity, 97% coverage of query (135 bits)
O30557 3-dehydroquinate dehydratase (EC 4.2.1.10) from Pseudomonas aeruginosa (see paper)
51% identity, 94% coverage of query (135 bits)
3DHQ_NEUCR / P05195 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; Quinic acid degradation cluster protein 2f; EC 4.2.1.10 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 9 papers)
43% identity, 94% coverage of query (134 bits)
5b6pB / A3M692 Structure of the dodecameric type-ii dehydrogenate dehydratase from acinetobacter baumannii at 2.00 a resolution (see paper)
50% identity, 92% coverage of query (134 bits)
5ydbA Crystal structure of the complex of type ii dehydroquinate dehydratase from acinetobacter baumannii with dehydroquinic acid at 1.76 angstrom resolution
50% identity, 92% coverage of query (134 bits)
Q0VMZ2 3-dehydroquinate dehydratase (EC 4.2.1.10) from Alcanivorax borkumensis (see paper)
50% identity, 94% coverage of query (131 bits)
3DHQ_CANAL / Q59Z17 Catabolic 3-dehydroquinase; cDHQase; 3-dehydroquinate dehydratase; EC 4.2.1.10 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
47% identity, 94% coverage of query (130 bits)
2y71A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-1,4,5-trihydroxy-3-((5-methylbenzo(b) thiophen-2-yl)methoxy)cyclohex-2-enecarboxylate
50% identity, 94% coverage of query (130 bits)
3n8nA Crystal structure of 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with inhibitor 6
50% identity, 94% coverage of query (130 bits)
2c4wA / Q48255 Type ii dehydroquinase from h. Pylori in complex with ah9095 (see paper)
46% identity, 97% coverage of query (129 bits)
AROQ_HELPY / Q48255 3-dehydroquinate dehydratase; 3-dehydroquinase; Type II DHQase; EC 4.2.1.10 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 2 papers)
Q48255 3-dehydroquinate dehydratase (EC 4.2.1.10) from Helicobacter pylori (see 8 papers)
46% identity, 97% coverage of query (128 bits)
2xd9A Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (4r,6r,7s)-4,6,7-trihydroxy-2-((e)-prop-1- enyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
46% identity, 97% coverage of query (128 bits)
2wksA Structure of helicobacter pylori type ii dehydroquinase with a new carbasugar-thiophene inhibitor.
46% identity, 97% coverage of query (128 bits)
4b6rA Structure of helicobacter pylori type ii dehydroquinase inhibited by (2s)-2-(4-methoxy)benzyl-3-dehydroquinic acid
46% identity, 97% coverage of query (128 bits)
4b6sA Structure of helicobacter pylori type ii dehydroquinase inhibited by (2s)-2-perfluorobenzyl-3-dehydroquinic acid
46% identity, 97% coverage of query (128 bits)
2xb9A Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (2r)-2-(4-methoxybenzyl)-3-dehydroquinic acid
46% identity, 97% coverage of query (128 bits)
1j2yA Crystal structure of the type ii 3-dehydroquinase
46% identity, 97% coverage of query (128 bits)
2xdaA Structure of helicobacter pylori type ii dehydroquinase in complex with inhibitor compound (4r,6r,7s)-2-(2-cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
46% identity, 97% coverage of query (128 bits)
1h0rA Type ii dehydroquinase from mycobacterium tuberculosis complexed with 2,3-anhydro-quinic acid
49% identity, 94% coverage of query (128 bits)
4ciyA Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-((1r)-1-hydroxy-2- phenyl)ethylcyclohex-2-en-1-carboxylic acid
49% identity, 94% coverage of query (126 bits)
4civA Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with (1r,4r,5r)-1,4,5-trihydroxy-3-hydroxymethylcyclohex- 2-ene-1-carboxylic acid
49% identity, 94% coverage of query (126 bits)
1h0sA 3-dehydroquinate dehydratase from mycobacterium tuberculosis in complex with 3-hydroxyimino-quinic acid
49% identity, 94% coverage of query (124 bits)
2y76A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-3-(benzo(b)thiophen-5-ylmethoxy)-2- (benzo(b) thiophen-5-ylmethyl)-1,4,5-trihydroxycyclohex-2- enecarboxylate
49% identity, 94% coverage of query (123 bits)
A5WDH9 3-dehydroquinate dehydratase (EC 4.2.1.10) from Psychrobacter sp. PRwf-1 (see paper)
46% identity, 94% coverage of query (122 bits)
4ki7A Design and structural analysis of aromatic inhibitors of type ii dehydroquinase from mycobacterium tuberculosis - compound 41c [3- hydroxy-5-(3-nitrophenoxy)benzoic acid]
49% identity, 94% coverage of query (122 bits)
4v0sA Crystal structure of mycobacterium tuberculosis type ii dehydroquinase d88n mutant inhibited by a 3-dehydroquinic acid derivative
47% identity, 94% coverage of query (122 bits)
B2A551 3-dehydroquinate dehydratase (EC 4.2.1.10) from Natranaerobius thermophilus (see paper)
49% identity, 94% coverage of query (121 bits)
4cixA Crystal structure of mycobacterium tuberculosis type 2 dehydroquinase in complex with(1r,4r,5r)-1,4,5-trihydroxy-3-((1s)-1-hydroxy-2- phenyl) ethylcyclohex-2-en-1-carboxylic acid
48% identity, 94% coverage of query (121 bits)
4b6qA Structure of mycobacterium tuberculosis type ii dehydroquinase inhibited by (2r)-2-(benzothiophen-5-yl)methyl-3-dehydroquinic acid
48% identity, 94% coverage of query (121 bits)
4ckyA Structure of the mycobacterium tuberculosis type ii dehydroquinase inhibited by a 3-dehydroquinic acid derivative
48% identity, 94% coverage of query (121 bits)
2y77A Structure of mycobacterium tuberculosis type ii dehydroquinase complexed with (1r,4s,5r)-3-(benzo(b)thiophen-2-ylmethoxy)-1,4,5- trihydroxy-2-(thiophen-2-ylmethyl)cyclohex-2-enecarboxylate
48% identity, 94% coverage of query (121 bits)
Q9PH97 3-dehydroquinate dehydratase (EC 4.2.1.10) from Xylella fastidiosa (see paper)
47% identity, 92% coverage of query (120 bits)
rifJ / Q7BUF8 5-deoxy-5-amino-3-dehydroquinate dehydratase from Amycolatopsis mediterranei (see paper)
43% identity, 97% coverage of query (116 bits)
D4S0D1 3-dehydroquinate dehydratase (EC 4.2.1.10) from Butyrivibrio crossotus (see paper)
44% identity, 94% coverage of query (115 bits)
6hs9A / D4S0D1 The crystal structure of type ii dehydroquinase from butyrivibrio crossotus dsm 2876
44% identity, 94% coverage of query (115 bits)
B9CK59 3-dehydroquinate dehydratase (EC 4.2.1.10) from Lancefieldella rimae (see paper)
44% identity, 89% coverage of query (115 bits)
6hsaA The crystal structure of type ii dehydroquinase from butyrivibrio crossotus dsm 2876
44% identity, 94% coverage of query (115 bits)
2c57A H.Pylori type ii dehydroquinase in complex with fa1
44% identity, 97% coverage of query (114 bits)
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Lawrence Berkeley National Laboratory