Searching for up to 100 curated homologs for WP_011736419.1 NCBI__GCF_000015045.1:WP_011736419.1 (573 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
30% identity, 98% coverage of query (268 bits)
Build an alignment for WP_011736419.1 and 1 homologs with ≥ 30% identity
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ILVB2_MYCTU / O06335 Putative acetolactate synthase large subunit IlvB2; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O06335 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
29% identity, 99% coverage of query (204 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
28% identity, 99% coverage of query (199 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
27% identity, 97% coverage of query (195 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
26% identity, 98% coverage of query (189 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
27% identity, 98% coverage of query (181 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
27% identity, 98% coverage of query (178 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
29% identity, 86% coverage of query (178 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
28% identity, 87% coverage of query (177 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
26% identity, 98% coverage of query (176 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
26% identity, 98% coverage of query (175 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
28% identity, 87% coverage of query (174 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
26% identity, 98% coverage of query (174 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
26% identity, 98% coverage of query (174 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
25% identity, 98% coverage of query (173 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
26% identity, 98% coverage of query (171 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
27% identity, 98% coverage of query (171 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
26% identity, 98% coverage of query (170 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
27% identity, 98% coverage of query (169 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
25% identity, 98% coverage of query (169 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
27% identity, 98% coverage of query (168 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
27% identity, 98% coverage of query (168 bits)
Q5VB49 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
26% identity, 98% coverage of query (164 bits)
A0A1X9M8K4 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Alkalihalobacillus krulwichiae (see paper)
26% identity, 99% coverage of query (164 bits)
A0A0M3TGF7 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
27% identity, 98% coverage of query (163 bits)
K7TWQ8 acetolactate synthase (EC 2.2.1.6) from Zea mays (see paper)
26% identity, 98% coverage of query (163 bits)
A0A0M4NDK0 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
27% identity, 98% coverage of query (163 bits)
Q5VB44 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
26% identity, 98% coverage of query (162 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
26% identity, 94% coverage of query (162 bits)
Q42768 acetolactate synthase (EC 2.2.1.6) from Gossypium hirsutum (see paper)
26% identity, 98% coverage of query (162 bits)
Q5M4L0 acetolactate synthase (EC 2.2.1.6) from Streptococcus thermophilus (see paper)
27% identity, 98% coverage of query (160 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
26% identity, 97% coverage of query (160 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
26% identity, 97% coverage of query (160 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
26% identity, 97% coverage of query (160 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
26% identity, 97% coverage of query (159 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
26% identity, 97% coverage of query (159 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
26% identity, 97% coverage of query (159 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
26% identity, 97% coverage of query (159 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
26% identity, 97% coverage of query (159 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
26% identity, 97% coverage of query (159 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
26% identity, 97% coverage of query (159 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
26% identity, 97% coverage of query (159 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
26% identity, 97% coverage of query (159 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
26% identity, 97% coverage of query (159 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
26% identity, 97% coverage of query (159 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
26% identity, 97% coverage of query (159 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
26% identity, 97% coverage of query (159 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
23% identity, 99% coverage of query (159 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
23% identity, 99% coverage of query (158 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
23% identity, 99% coverage of query (158 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
23% identity, 99% coverage of query (158 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
23% identity, 99% coverage of query (158 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
23% identity, 99% coverage of query (157 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
23% identity, 99% coverage of query (157 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 99% coverage of query (157 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
23% identity, 99% coverage of query (156 bits)
xsc / Q84H44 sulfoacetaldehyde acetyltransferase monomer (EC 2.3.3.15) from Castellaniella defragrans (see paper)
XSC_CASDE / Q84H44 Sulfoacetaldehyde acetyltransferase; EC 2.3.3.15 from Castellaniella defragrans (Alcaligenes defragrans) (see paper)
Q84H44 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Castellaniella defragrans (see paper)
27% identity, 94% coverage of query (156 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
23% identity, 99% coverage of query (156 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 99% coverage of query (156 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
23% identity, 99% coverage of query (154 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
25% identity, 98% coverage of query (152 bits)
als / CAA66718.1 acetolactate synthase from Synechocystis sp (see paper)
26% identity, 98% coverage of query (152 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
23% identity, 99% coverage of query (152 bits)
F9M3T8 pyruvate oxidase (EC 1.2.3.3) from Streptococcus sanguinis (see 2 papers)
25% identity, 99% coverage of query (150 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
23% identity, 98% coverage of query (150 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
26% identity, 99% coverage of query (148 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
26% identity, 99% coverage of query (148 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
25% identity, 99% coverage of query (148 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
25% identity, 99% coverage of query (147 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
25% identity, 99% coverage of query (147 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
25% identity, 99% coverage of query (147 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
25% identity, 99% coverage of query (146 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
25% identity, 99% coverage of query (144 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
24% identity, 94% coverage of query (143 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
25% identity, 99% coverage of query (142 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
26% identity, 97% coverage of query (140 bits)
7egvA Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
24% identity, 98% coverage of query (140 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
24% identity, 99% coverage of query (135 bits)
8rphD 8rphD (see paper)
24% identity, 98% coverage of query (135 bits)
8rpjA Janthe from janthinobacterium sp. Hh01
24% identity, 98% coverage of query (135 bits)
8rpiA Janthe from janthinobacterium sp. Hh01, lactyl-thdp
24% identity, 98% coverage of query (135 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
25% identity, 99% coverage of query (133 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
26% identity, 99% coverage of query (133 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
25% identity, 99% coverage of query (131 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
24% identity, 97% coverage of query (131 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
24% identity, 97% coverage of query (131 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
25% identity, 99% coverage of query (130 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
24% identity, 97% coverage of query (130 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
25% identity, 99% coverage of query (129 bits)
1v5gA Crystal structure of the reaction intermediate between pyruvate oxidase containing fad and tpp, and substrate pyruvate
23% identity, 98% coverage of query (126 bits)
1v5fA Crystal structure of pyruvate oxidase complexed with fad and tpp, from aerococcus viridans
23% identity, 98% coverage of query (126 bits)
2djiA / A9X9K8 Crystal structure of pyruvate oxidase from aerococcus viridans containing fad (see paper)
23% identity, 98% coverage of query (126 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase (see paper)
25% identity, 97% coverage of query (123 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
24% identity, 97% coverage of query (122 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
24% identity, 97% coverage of query (122 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 87% coverage of query (122 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 87% coverage of query (122 bits)
PoxB / b0871 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli K-12 substr. MG1655 (see 70 papers)
poxB / P07003 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli (strain K12) (see 69 papers)
POXB_ECOLI / P07003 Pyruvate dehydrogenase [ubiquinone]; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductase; EC 1.2.5.1 from Escherichia coli (strain K12) (see 13 papers)
P07003 pyruvate dehydrogenase (quinone) (EC 1.2.5.1) from Escherichia coli (see paper)
23% identity, 100% coverage of query (115 bits)
3ey9A / P07003 Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from escherichia coli (see paper)
24% identity, 99% coverage of query (114 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
23% identity, 98% coverage of query (114 bits)
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