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Searching for up to 100 curated homologs for WP_011763870.1 NCBI__GCF_000061505.1:WP_011763870.1 (306 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ilvE / O86428 branched-chain-amino-acid aminotransferase subunit (EC 2.6.1.6; EC 2.6.1.42) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
O86428 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Pseudomonas aeruginosa (see paper)
    57% identity, 99% coverage of query (386 bits)

Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Pseudomonas stutzeri RCH2
    59% identity, 99% coverage of query (382 bits)

4whxA X-ray crystal structure of an amino acid aminotransferase from burkholderia pseudomallei bound to the co-factor pyridoxal phosphate
    58% identity, 99% coverage of query (374 bits)

BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Burkholderia phytofirmans PsJN
    56% identity, 100% coverage of query (366 bits)

2ej0B / Q5SM19 Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase with pyridoxamine 5'-phosphate
    50% identity, 97% coverage of query (298 bits)

ilvE / O27481 branched-chain-amino-acid aminotransferase subunit (EC 2.6.1.42) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 3 papers)
    48% identity, 97% coverage of query (281 bits)

IlvE / b3770 branched-chain-amino-acid aminotransferase (EC 2.6.1.1; EC 2.6.1.57; EC 2.6.1.27; EC 2.6.1.42; EC 2.6.1.6) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ilvE / P0AB80 branched-chain-amino-acid aminotransferase (EC 2.6.1.1; EC 2.6.1.42; EC 2.6.1.6) from Escherichia coli (strain K12) (see paper)
ilvE / RF|YP_026247 branched-chain-amino-acid aminotransferase; EC 2.6.1.42 from Escherichia coli K12 (see 11 papers)
    48% identity, 96% coverage of query (279 bits)

1i1lA / P0AB80 Crystal structure of eschelichia coli branched-chain amino acid aminotransferase. (see paper)
    48% identity, 96% coverage of query (279 bits)

1iyeA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
    48% identity, 96% coverage of query (279 bits)

1iydA Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
    48% identity, 96% coverage of query (279 bits)

1i1mA Crystal structure of escherichia coli branched-chain amino acid aminotransferase.
    48% identity, 96% coverage of query (279 bits)

2ej3A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with gabapentin
    48% identity, 97% coverage of query (278 bits)

2eiyA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with 4-methylvaleric acid
    48% identity, 97% coverage of query (278 bits)

1wrvA Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase
    48% identity, 97% coverage of query (278 bits)

2ej2A Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
    48% identity, 97% coverage of query (278 bits)

ABZR86_RS11580 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Dyella japonica UNC79MFTsu3.2
    44% identity, 97% coverage of query (250 bits)

F2L0W0 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermoproteus uzoniensis (see 3 papers)
    43% identity, 97% coverage of query (245 bits)

6thqB / F2L0W0 Crystal structure of branched-chain aminotransferase from thermophilic archaea thermoproteus uzoniensis with norvaline
    43% identity, 97% coverage of query (244 bits)

F0QW25 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Vulcanisaeta moutnovskia (see 2 papers)
    41% identity, 97% coverage of query (241 bits)

5e25A / A0A0A7GJ30 Crystal structure of branched-chain aminotransferase from thermophilic archaea geoglobus acetivorans complexed with alpha-ketoglutarate (see paper)
    41% identity, 92% coverage of query (215 bits)

5mr0D / O29329 Thermophilic archaeal branched-chain amino acid transaminases from geoglobus acetivorans and archaeoglobus fulgidus: biochemical and structural characterisation (see paper)
    40% identity, 94% coverage of query (214 bits)

E6TUA8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Evansella cellulosilytica (see paper)
    38% identity, 93% coverage of query (198 bits)

GB|AAU18968.1 branched-chain amino acid aminotransferase 2; EC 2.6.1.42 from Bacillus cereus E33L (see paper)
    39% identity, 93% coverage of query (197 bits)

A0A1B1L2T7 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Bacillus thuringiensis (see paper)
    39% identity, 93% coverage of query (197 bits)

ilvE / A6UWA0 branched-chain amino acid aminotransferase subunit (EC 2.6.1.6; EC 2.6.1.42) from Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3) (see 3 papers)
A6UWA0 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Methanococcus aeolicus (see paper)
    40% identity, 91% coverage of query (195 bits)

B9L0B7 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermomicrobium roseum (see paper)
    39% identity, 97% coverage of query (187 bits)

D0LR31 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Haliangium ochraceum (see paper)
    35% identity, 96% coverage of query (167 bits)

6h65C / D0LR31 Crystal structure of the branched-chain-amino-acid aminotransferase from haliangium ochraceum
    35% identity, 96% coverage of query (167 bits)

P54691 branched-chain-amino-acid transaminase (EC 2.6.1.42); glutamate-prephenate aminotransferase (EC 2.6.1.79) from Synechocystis sp. (see paper)
    34% identity, 96% coverage of query (166 bits)

D1CCW1 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermobaculum terrenum (see paper)
    35% identity, 100% coverage of query (166 bits)

6q8eA Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum in pmp-form
    36% identity, 97% coverage of query (162 bits)

7neaA / D1CCW1 Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum (m3 mutant). (see paper)
    35% identity, 97% coverage of query (155 bits)

A6UP94 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Methanococcus vannielii (see paper)
    33% identity, 97% coverage of query (149 bits)

A0A0A0LJI6 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    34% identity, 91% coverage of query (145 bits)

7p3tB / B8KQT8 Transaminase of gamma-proteobacterium (see paper)
    33% identity, 92% coverage of query (134 bits)

5fr9A Structure of transaminase ata-117 arrmut11 from arthrobacter sp. Knk168 inhibited with 1-(4-bromophenyl)-2-fluoroethylamine
    32% identity, 92% coverage of query (125 bits)

7z79B / T1XIY1 Crystal structure of aminotransferase-like protein from variovorax paradoxus
    32% identity, 95% coverage of query (117 bits)

8ivpB / A1TDP1 Crystal structure of mv in complex with llp and fru from mycobacterium vanbaalenii
    32% identity, 95% coverage of query (112 bits)

7dbeB Structure of a novel transaminase
    31% identity, 92% coverage of query (107 bits)

3wwhA / F7J696 Crystal structure of the first r-stereoselective -transaminase identified from arthrobacter sp. Knk168 (ferm-bp-5228) (see paper)
    31% identity, 92% coverage of query (105 bits)

Build an alignment

Build an alignment for WP_011763870.1 and 40 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4cmdA / C7YVL8 The (r)-selective transaminase from nectria haematococca (see paper)
    27% identity, 92% coverage of query (104 bits)

DAAA_BACYM / P19938 D-alanine aminotransferase; D-amino acid aminotransferase; D-amino acid transaminase; DAAT; D-aspartate aminotransferase; EC 2.6.1.21 from Bacillus sp. (strain YM-1) (see 3 papers)
dat D-alanine aminotransferase; EC 2.6.1.21 from Bacillus sp. YM-1 (see 6 papers)
    28% identity, 92% coverage of query (104 bits)

4cmfA The (r)-selective transaminase from nectria haematococca with inhibitor bound
    27% identity, 92% coverage of query (104 bits)

3lqsA Complex structure of d-amino acid aminotransferase and 4-amino-4,5- dihydro-thiophenecarboxylic acid (adta)
    27% identity, 92% coverage of query (104 bits)

3daaA Crystallographic structure of d-amino acid aminotransferase inactivated by pyridoxyl-d-alanine
    28% identity, 92% coverage of query (104 bits)

2daaA Crystallographic structure of d-amino acid aminotransferase inactivated by d-cycloserine
    28% identity, 92% coverage of query (104 bits)

1daaA Crystallographic structure of d-amino acid aminotransferase complexed with pyridoxal-5'-phosphate
    28% identity, 92% coverage of query (104 bits)

Q9LPM9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see 2 papers)
    30% identity, 86% coverage of query (103 bits)

ilvE / O31461 branched-chain amino acid aminotransferase (EC 2.6.1.6; EC 2.6.1.42) from Bacillus subtilis (strain 168) (see 4 papers)
ILVE1_BACSU / O31461 Branched-chain-amino-acid transaminase 1; BCAT 1; EC 2.6.1.42 from Bacillus subtilis (strain 168) (see paper)
    30% identity, 98% coverage of query (103 bits)

6xwbA Crystal structure of an r-selective transaminase from thermomyces stellatus. (see paper)
    27% identity, 91% coverage of query (102 bits)

1a0gB / P19938 L201a mutant of d-amino acid aminotransferase complexed with pyridoxamine-5'-phosphate (see paper)
    27% identity, 92% coverage of query (102 bits)

Q9FYA6 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    28% identity, 97% coverage of query (101 bits)

3ht5A / P9WQ75 Crystal structure of ilve a branched chain amino acid transaminase from mycobacterium tuberculosis (see paper)
    31% identity, 99% coverage of query (100 bits)

ILVE_MYCTU / P9WQ75 Branched-chain-amino-acid aminotransferase; BCAT; EC 2.6.1.42 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WQ75 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Mycobacterium tuberculosis (see 4 papers)
    31% identity, 99% coverage of query (100 bits)

6fteB / A0A0D2C5V9 Crystal structure of an (r)-selective amine transaminase from exophiala xenobiotica
    25% identity, 92% coverage of query (99.8 bits)

BCAT3 / Q9M401 branched-chain aminotransferase from Arabidopsis thaliana (see paper)
BCAT3_ARATH / Q9M401 Branched-chain-amino-acid aminotransferase 3, chloroplastic; Atbcat-3; EC 2.6.1.42; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9M401 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    29% identity, 90% coverage of query (97.8 bits)

Q0E9S8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Helicobacter pylori (see paper)
    30% identity, 96% coverage of query (97.8 bits)

O26004 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Helicobacter pylori (see paper)
    30% identity, 96% coverage of query (97.4 bits)

dat / P54693 D-alanine aminotransferase monomer (EC 2.6.1.21) from Lysinibacillus sphaericus (see 7 papers)
    27% identity, 85% coverage of query (96.7 bits)

pabC / P28821 4-amino-4-deoxychorismate pyruvate-lyase (EC 4.1.3.38) from Bacillus subtilis (strain 168) (see paper)
PABC_BACSU / P28821 Aminodeoxychorismate lyase; 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL; EC 4.1.3.38 from Bacillus subtilis (strain 168) (see paper)
    30% identity, 90% coverage of query (96.7 bits)

5u3fA Structure of mycobacterium tuberculosis ilve, a branched-chain amino acid transaminase, in complex with d-cycloserine derivative
    30% identity, 99% coverage of query (96.3 bits)

8ahuA / F4KWH0 Crystal structure of d-amino acid aminotrensferase from haliscomenobacter hydrossis complexed with d-cycloserine (see paper)
    28% identity, 92% coverage of query (95.9 bits)

Q70KX9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Hordeum vulgare (see paper)
    30% identity, 83% coverage of query (95.9 bits)

7p7xA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis (holo form).
    28% identity, 92% coverage of query (95.9 bits)

6snlD / A0A0D1XFW6 (R)-selective amine transaminase from exophiala sideris (see paper)
    25% identity, 93% coverage of query (94.4 bits)

4ce5A / Q0C8G1 First crystal structure of an (r)-selective omega-transaminase from aspergillus terreus (see paper)
    25% identity, 92% coverage of query (93.6 bits)

Q5FTR3 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Gluconobacter oxydans (see paper)
    30% identity, 90% coverage of query (93.6 bits)

4ce5B First crystal structure of an (r)-selective omega-transaminase from aspergillus terreus
    25% identity, 92% coverage of query (93.6 bits)

BCAT4 / Q9LE06 methionine transaminase (EC 2.6.1.88) from Arabidopsis thaliana (see paper)
BCAT4_ARATH / Q9LE06 Methionine aminotransferase BCAT4; Branched-chain-amino-acid aminotransferase 4; Atbcat-4; Methionine-oxo-acid transaminase BCAT4; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LE06 branched-chain-amino-acid transaminase (EC 2.6.1.42); methionine transaminase (EC 2.6.1.88) from Arabidopsis thaliana (see 2 papers)
    28% identity, 88% coverage of query (93.2 bits)

RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) from Cupriavidus basilensis FW507-4G11
    30% identity, 96% coverage of query (92.4 bits)

6xu3C (R)-selective amine transaminase from shinella sp. (see paper)
    25% identity, 96% coverage of query (92.4 bits)

8raiA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis point mutant r90i complexed with phenylhydrazine
    28% identity, 92% coverage of query (92.4 bits)

6xu3A (R)-selective amine transaminase from shinella sp.
    25% identity, 96% coverage of query (92.4 bits)

B6RFK8 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Nicotiana benthamiana (see paper)
    29% identity, 98% coverage of query (92.0 bits)

6xu3B (R)-selective amine transaminase from shinella sp.
    25% identity, 96% coverage of query (92.0 bits)

BCAT2_ARATH / Q9M439 Branched-chain-amino-acid aminotransferase 2, chloroplastic; Atbcat-2; EC 2.6.1.42 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M439 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    29% identity, 85% coverage of query (91.7 bits)

8aykA Crystal structure of d-amino acid aminotrensferase from aminobacterium colombiense complexed with d-glutamate
    26% identity, 92% coverage of query (91.7 bits)

8ayjA Crystal structure of d-amino acid aminotransferase from aminobacterium colombiens complexed with 3-aminooxypropionic acid
    26% identity, 92% coverage of query (91.7 bits)

8aieA Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense complexed with d-cycloserine
    26% identity, 92% coverage of query (91.7 bits)

8aieB Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense complexed with d-cycloserine
    26% identity, 92% coverage of query (91.7 bits)

A0A2Z4MEX9 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Brevibacillus brevis (see paper)
    28% identity, 88% coverage of query (91.3 bits)

ILVE_MYCS2 / A0R066 Branched-chain-amino-acid aminotransferase; BCAT; EC 2.6.1.42 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
A0R066 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Mycolicibacterium smegmatis (see paper)
    31% identity, 96% coverage of query (90.9 bits)

3dtfA / A0R066 Structural analysis of mycobacterial branched chain aminotransferase- implications for inhibitor design (see paper)
    31% identity, 96% coverage of query (90.9 bits)

3dtgA Structural analysis of mycobacterial branched chain aminotransferase- implications for inhibitor design
    31% identity, 96% coverage of query (90.9 bits)

8yrvA Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid
    28% identity, 92% coverage of query (90.5 bits)

A0A0A0LN48 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    28% identity, 84% coverage of query (89.0 bits)

8onjA / D5EHC5 Crystal structure of d-amino acid aminotransferase from aminobacterium colombiense point mutant r88l (see paper)
    26% identity, 92% coverage of query (89.0 bits)

BCAT2_HUMLU / K7QHS5 Branched-chain amino acid aminotransferase 2, chloroplastic; HlBCAT2; EC 2.6.1.42 from Humulus lupulus (European hop) (see paper)
    27% identity, 92% coverage of query (89.0 bits)

A0A0A0KG15 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Cucumis sativus var. sativus (see paper)
    29% identity, 92% coverage of query (88.6 bits)

4chiA / Q4WH08 (R)-selective amine transaminase from aspergillus fumigatus at 1.27 a resolution (see paper)
    27% identity, 76% coverage of query (87.0 bits)

pabC-2 / B8Y8J0 4-amino-4-deoxychorismate lyase (EC 4.1.3.38) from Streptomyces sp. FR-008 (see 2 papers)
B8Y8J0 aminodeoxychorismate lyase (EC 4.1.3.38) from Streptomyces sp. (see paper)
    33% identity, 91% coverage of query (87.0 bits)

4uugA The (r)-selective amine transaminase from aspergillus fumigatus with inhibitor bound
    27% identity, 76% coverage of query (87.0 bits)

ADCL / Q8L493 aminodeoxychorismate lyase (EC 4.1.3.38) from Arabidopsis thaliana (see 3 papers)
DAAA_ARATH / Q8L493 D-amino-acid transaminase, chloroplastic; Aminodeoxychorismate lyase; AtADCL; Branched-chain-amino-acid aminotransferase-like protein 3; EC 2.6.1.21; EC 4.1.3.38 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8L493 D-amino-acid transaminase (EC 2.6.1.21) from Arabidopsis thaliana (see paper)
    25% identity, 88% coverage of query (85.1 bits)

ilvK / P39576 branched-chain amino acid aminotransferase (EC 2.6.1.42; EC 2.6.1.6) from Bacillus subtilis (strain 168) (see 2 papers)
ILVE2_BACSU / P39576 Branched-chain-amino-acid aminotransferase 2; BCAT 2; Vegetative protein 85; VEG85; EC 2.6.1.42 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 93% coverage of query (84.0 bits)

BCAT1_HUMLU / K7QKH1 Branched-chain amino acid aminotransferase 1, mitochondrial; HlBCAT1; EC 2.6.1.42 from Humulus lupulus (European hop) (see paper)
    29% identity, 86% coverage of query (83.6 bits)

Q5DQ95 aminodeoxychorismate lyase (EC 4.1.3.38) from Solanum lycopersicum (see 2 papers)
    28% identity, 84% coverage of query (79.3 bits)

Q93Y32 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Arabidopsis thaliana (see paper)
    26% identity, 97% coverage of query (77.0 bits)

A0A5Q8BPF5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Lacticaseibacillus paracasei (see paper)
    28% identity, 96% coverage of query (76.6 bits)

3uyyB / Q9RTX5 Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis (see paper)
    28% identity, 96% coverage of query (75.9 bits)

Q9RTX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Deinococcus radiodurans (see paper)
    28% identity, 96% coverage of query (75.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory