Searching for up to 100 curated homologs for WP_011779260.1 NCBI__GCF_000015305.1:WP_011779260.1 (255 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxyacyl-CoA dehydrogenase type II; Hydroxysteroid dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.62; EC 1.1.1.-; EC 1.1.1.53 from Drosophila melanogaster (Fruit fly) (see 7 papers)
48% identity, 99% coverage of query (233 bits)
8cbkC Structure of human mitochondrial rnase p in complex with mitochondrial pre-tRNA-his(5,ser) (see paper)
47% identity, 99% coverage of query (228 bits)
HSD17B10 / Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35; EC 1.1.1.178; EC 1.1.1.239) from Homo sapiens (see 3 papers)
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Homo sapiens (Human) (see 22 papers)
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Homo sapiens (see 2 papers)
47% identity, 99% coverage of query (228 bits)
1e3wD / O70351 Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate (see paper)
47% identity, 99% coverage of query (228 bits)
1u7tA Crystal structure of abad/hsd10 with a bound inhibitor
47% identity, 99% coverage of query (228 bits)
O70351 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Rattus norvegicus (Rat)
47% identity, 99% coverage of query (228 bits)
HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Mus musculus (Mouse) (see paper)
47% identity, 99% coverage of query (220 bits)
1e6wC Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol
46% identity, 99% coverage of query (217 bits)
4xgnA / Q2T0K5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase in complex with NAD from burkholderia thailandensis
48% identity, 100% coverage of query (208 bits)
fadB2x / Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
48% identity, 100% coverage of query (206 bits)
1uayA / Q7SIA1 Crystal structure of type ii 3-hydroxyacyl-coa dehydrogenase from thermus thermophilus hb8
49% identity, 98% coverage of query (205 bits)
6ujkA / P9WGQ7 Crystal structure of a probable short-chain type dehydrogenase/reductase (rv1144) from mycobacterium tuberculosis with bound NAD
46% identity, 100% coverage of query (203 bits)
4o5oB / A0A0H3G6B0 X-ray crystal structure of a 3-hydroxyacyl-coa dehydrogenase from brucella suis
44% identity, 100% coverage of query (194 bits)
7n09A / F1L0H2 Structural basis for branched substrate selectivity in a ketoreductase from ascaris suum
45% identity, 98% coverage of query (192 bits)
3ppiA / A0A0H3A4S5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from mycobacterium avium (see paper)
42% identity, 100% coverage of query (185 bits)
IDOLDH / G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see paper)
IDLDH_IPSPI / G5DGA8 Ipsdienol dehydrogenase; EC 1.1.1.386 from Ips pini (Pine engraver beetle) (see paper)
G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see 2 papers)
33% identity, 98% coverage of query (122 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
30% identity, 97% coverage of query (112 bits)
2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
35% identity, 96% coverage of query (110 bits)
Q5SLC4 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermus thermophilus (see paper)
36% identity, 96% coverage of query (108 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
31% identity, 98% coverage of query (107 bits)
gutD / CAA05517.1 glucitol-6-phosphate dehydrogenase from Clostridium beijerinckii (see paper)
32% identity, 91% coverage of query (102 bits)
6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
34% identity, 90% coverage of query (101 bits)
SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
35% identity, 99% coverage of query (101 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
31% identity, 98% coverage of query (101 bits)
LINC_SPHIU / D4YYG1 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
33% identity, 97% coverage of query (100 bits)
Build an alignment for WP_011779260.1 and 25 homologs with ≥ 30% identity
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uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
29% identity, 98% coverage of query (97.4 bits)
1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
29% identity, 98% coverage of query (97.4 bits)
5jydB / B4EEE3 Crystal structure of a putative short chain dehydrogenase from burkholderia cenocepacia
33% identity, 96% coverage of query (97.1 bits)
7xqmB / Q72LQ6 Indel-mutant short chain dehydrogenase bound to sah (see paper)
34% identity, 96% coverage of query (96.3 bits)
4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
32% identity, 87% coverage of query (95.9 bits)
budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
27% identity, 98% coverage of query (95.9 bits)
BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
34% identity, 82% coverage of query (95.1 bits)
W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
31% identity, 97% coverage of query (94.7 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
30% identity, 98% coverage of query (94.7 bits)
RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_MEDG7 / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Mediterraneibacter gnavus (strain ATCC 29149 / DSM 114966 / JCM 6515 / VPI C7-9) (Ruminococcus gnavus) (see paper)
29% identity, 98% coverage of query (94.0 bits)
HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
31% identity, 87% coverage of query (93.6 bits)
W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
31% identity, 97% coverage of query (93.2 bits)
6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
27% identity, 96% coverage of query (93.2 bits)
6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
27% identity, 96% coverage of query (93.2 bits)
6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
27% identity, 96% coverage of query (93.2 bits)
7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
33% identity, 83% coverage of query (92.4 bits)
W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
31% identity, 97% coverage of query (92.0 bits)
6zyzA Structure of the borneol dehydrogenases of salvia rosmarinus with NAD+ (see paper)
31% identity, 97% coverage of query (91.7 bits)
G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
30% identity, 89% coverage of query (91.7 bits)
4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
32% identity, 87% coverage of query (91.7 bits)
3ijrF / A0A6L8PL20 2.05 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD+
27% identity, 97% coverage of query (90.9 bits)
3i3oA 2.06 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD-acetone
27% identity, 97% coverage of query (90.9 bits)
2ekpA / Q53W82 Structure of tt0495 protein from thermus thermophilus (see paper)
30% identity, 96% coverage of query (90.5 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
32% identity, 98% coverage of query (90.5 bits)
FADH_BACSU / O34717 Probable 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]; EC 1.3.1.34 from Bacillus subtilis (strain 168) (see paper)
31% identity, 99% coverage of query (90.5 bits)
8y83A Crystal structure of a ketoreductase from sphingobacterium siyangense sy1 with co-enzyme
32% identity, 96% coverage of query (90.1 bits)
GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
33% identity, 97% coverage of query (90.1 bits)
ptmO8 / D8L2W5 ent-kauranol 7β-dehydrogenase from Streptomyces platensis (see paper)
32% identity, 97% coverage of query (89.7 bits)
4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
33% identity, 97% coverage of query (89.4 bits)
Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
29% identity, 96% coverage of query (88.2 bits)
Q7XZH5 xanthoxin dehydrogenase (EC 1.1.1.288) from Oryza sativa (see paper)
31% identity, 77% coverage of query (87.8 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
25% identity, 98% coverage of query (87.8 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
26% identity, 97% coverage of query (87.4 bits)
BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
30% identity, 98% coverage of query (87.4 bits)
CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
28% identity, 96% coverage of query (87.4 bits)
4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
28% identity, 96% coverage of query (87.4 bits)
3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
28% identity, 99% coverage of query (87.0 bits)
Q93Y47 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51) from Digitalis lanata (see 2 papers)
3bhsd / CAC93667.1 3-beta-hydroxysteroiddehydrogenase from Digitalis lanata (see paper)
30% identity, 97% coverage of query (87.0 bits)
KDUD_BACSU / P50842 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Bacillus subtilis (strain 168) (see paper)
30% identity, 98% coverage of query (87.0 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
28% identity, 96% coverage of query (87.0 bits)
Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa (see paper)
31% identity, 97% coverage of query (86.3 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
31% identity, 98% coverage of query (86.3 bits)
fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
27% identity, 96% coverage of query (86.3 bits)
G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
28% identity, 98% coverage of query (85.5 bits)
BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
29% identity, 99% coverage of query (85.5 bits)
1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
31% identity, 92% coverage of query (85.1 bits)
1nfqA Rv2002 gene product from mycobacterium tuberculosis
31% identity, 92% coverage of query (85.1 bits)
4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
29% identity, 89% coverage of query (85.1 bits)
baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
29% identity, 89% coverage of query (84.7 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
30% identity, 91% coverage of query (84.7 bits)
NEPS1_NEPRA / A0A3Q8GL18 (+)-cis,trans-nepetalactol synthase NEPS1; Nepetalactol-related short-chain dehydrogenase; Nepetalactol dehydrogenase; Nepetalactol-related short-chain reductase 1; Nepetalactol-related SDR1; NmNEPS1; EC 5.5.1.34; EC 1.1.1.419 from Nepeta racemosa (Catmint) (Raceme catnip) (see 2 papers)
A0A3Q8GL18 nepetalactol dehydrogenase (EC 1.1.1.419); (+)-cis,trans-nepetalactol synthase (EC 5.5.1.34) from Nepeta racemosa (see 2 papers)
29% identity, 99% coverage of query (84.3 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
30% identity, 98% coverage of query (84.3 bits)
HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
31% identity, 91% coverage of query (84.3 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
31% identity, 96% coverage of query (84.0 bits)
1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
28% identity, 96% coverage of query (84.0 bits)
1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
28% identity, 96% coverage of query (84.0 bits)
7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
29% identity, 98% coverage of query (84.0 bits)
1ahhA 7 alpha-hydroxysteroid dehydrogenase complexed with NAD+
31% identity, 98% coverage of query (84.0 bits)
HdhA / b1619 7-α-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
hdhA / P0AET8 7-α-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Escherichia coli (strain K12) (see 9 papers)
HDHA_ECOLI / P0AET8 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NAD-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.159 from Escherichia coli (strain K12) (see 3 papers)
1ahiA / P0AET8 7 alpha-hydroxysteroid dehydrogenase complexed with nadh and 7-oxo glycochenodeoxycholic acid (see paper)
hdhA 7-alpha-hydroxysteroid dehydrogenase; EC 1.1.1.159 from Escherichia coli K12 (see 6 papers)
31% identity, 98% coverage of query (83.6 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
30% identity, 98% coverage of query (83.6 bits)
5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
31% identity, 82% coverage of query (83.6 bits)
3tzcA Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg)(y155f) from vibrio cholerae (see paper)
30% identity, 98% coverage of query (82.8 bits)
PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
29% identity, 98% coverage of query (82.4 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
30% identity, 96% coverage of query (82.4 bits)
4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
30% identity, 96% coverage of query (82.4 bits)
6zt2A 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 3-chloro-2,6-difluorophenol
28% identity, 82% coverage of query (82.0 bits)
6zdiA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 2-fluoro-5-nitrophenol
28% identity, 82% coverage of query (82.0 bits)
6zdeA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with pentafluorophenol
28% identity, 82% coverage of query (82.0 bits)
6gtuA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fragment j6
28% identity, 82% coverage of query (81.6 bits)
6emmA / Q9BPX1 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with salicylic acid
28% identity, 82% coverage of query (81.6 bits)
6gtbA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb211
28% identity, 82% coverage of query (81.3 bits)
5o7cA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
28% identity, 82% coverage of query (81.3 bits)
5o6zA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
28% identity, 82% coverage of query (81.3 bits)
6qckA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb262
28% identity, 82% coverage of query (81.3 bits)
5o6oA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor
28% identity, 82% coverage of query (81.3 bits)
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Lawrence Berkeley National Laboratory