Searching for up to 100 curated homologs for WP_011812941.1 NCBI__GCF_000015585.1:WP_011812941.1 (379 a.a.)
Found high-coverage hits (≥70%) to 56 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
51% identity, 97% coverage of query (365 bits)
P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
54% identity, 91% coverage of query (360 bits)
1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
54% identity, 91% coverage of query (360 bits)
1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
54% identity, 91% coverage of query (360 bits)
A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
56% identity, 92% coverage of query (360 bits)
3aeyA Apo form of threonine synthase from thermus thermophilus hb8
54% identity, 91% coverage of query (360 bits)
2zsjA / O66740 Crystal structure of threonine synthase from aquifex aeolicus vf5
50% identity, 98% coverage of query (358 bits)
O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus (see paper)
50% identity, 98% coverage of query (358 bits)
THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis (see 2 papers)
56% identity, 92% coverage of query (358 bits)
2d1fA / P9WG59 Structure of mycobacterium tuberculosis threonine synthase (see paper)
56% identity, 92% coverage of query (358 bits)
6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
52% identity, 92% coverage of query (356 bits)
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
52% identity, 92% coverage of query (356 bits)
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
51% identity, 91% coverage of query (339 bits)
THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
46% identity, 97% coverage of query (302 bits)
THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
36% identity, 91% coverage of query (195 bits)
THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
34% identity, 99% coverage of query (192 bits)
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
34% identity, 99% coverage of query (192 bits)
2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
33% identity, 99% coverage of query (174 bits)
DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
31% identity, 90% coverage of query (128 bits)
Build an alignment for WP_011812941.1 and 19 homologs with ≥ 30% identity
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T1KF23 L-3-cyanoalanine synthase (EC 4.4.1.9) from Tetranychus urticae (see paper)
27% identity, 84% coverage of query (74.3 bits)
7mfjBBB / T1KF23 7mfjBBB (see paper)
27% identity, 84% coverage of query (72.0 bits)
6xo2A / T1KF23 Structural characterization of beta cyanoalanine synthase from tetranychus urticae (two-spotted spider mite) (see paper)
26% identity, 84% coverage of query (69.3 bits)
4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
26% identity, 78% coverage of query (67.4 bits)
1jbqA Structure of human cystathionine beta-synthase: a unique pyridoxal 5'- phosphate dependent hemeprotein
26% identity, 78% coverage of query (65.5 bits)
cysK / P56067 cystathionine β-synthase (O-acetyl-L-serine) monomer (EC 4.2.1.22; EC 2.5.1.134; EC 2.5.1.47) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
6ahiB / P56067 Crystal structure of o-acetylserine dependent cystathionine beta- synthase from helicobacter pylori. (see paper)
27% identity, 85% coverage of query (64.7 bits)
8s5hA / P35520 Full-length human cystathionine beta-synthase with c-terminal 6xhis- tag, basal state, helical reconstruction (see paper)
26% identity, 78% coverage of query (64.7 bits)
7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
26% identity, 78% coverage of query (64.7 bits)
Cbs / P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus (see 2 papers)
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat) (see 3 papers)
27% identity, 78% coverage of query (64.3 bits)
CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
26% identity, 78% coverage of query (64.3 bits)
A0A220K819 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus (see paper)
24% identity, 87% coverage of query (63.2 bits)
5ohxA / Q2V0C9 Structure of active cystathionine b-synthase from apis mellifera (see paper)
25% identity, 74% coverage of query (62.8 bits)
A0A220K8J3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi (see paper)
25% identity, 85% coverage of query (62.8 bits)
Q54HH2 D-Serine ammonia-lyase (EC 4.3.1.18) from Dictyostelium discoideum (see paper)
25% identity, 77% coverage of query (62.4 bits)
A0A220K8D2 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi (see paper)
27% identity, 85% coverage of query (62.4 bits)
A0A0U3S5Y4 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae (see paper)
24% identity, 84% coverage of query (61.2 bits)
CBS2_CAEEL / Q9N4K2 Putative cystathionine beta-synthase cbs-2; EC 4.2.1.22 from Caenorhabditis elegans (see 2 papers)
26% identity, 82% coverage of query (60.8 bits)
2bhtA / P16703 Crystal structure of o-acetylserine sulfhydrylase b (see paper)
27% identity, 78% coverage of query (60.5 bits)
A0A220K8A8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Zygaena filipendulae (see paper)
24% identity, 84% coverage of query (59.3 bits)
CysM / b2421 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
cysM / P16703 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1) from Escherichia coli (strain K12) (see 15 papers)
CYSM_ECOLI / P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
27% identity, 78% coverage of query (59.3 bits)
P29848 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) (EC 2.5.1.144); cysteine synthase (EC 2.5.1.47) from Salmonella enterica subsp. enterica serovar Typhimurium (see 9 papers)
27% identity, 79% coverage of query (58.9 bits)
A0A220K8H3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Gonepteryx rhamni (see paper)
23% identity, 84% coverage of query (58.9 bits)
mecA cystathionine beta-synthase; EC 4.2.1.22 from Emericella nidulans (see 2 papers)
23% identity, 82% coverage of query (58.2 bits)
A0A220K835 L-3-cyanoalanine synthase (EC 4.4.1.9) from Spodoptera littoralis (see paper)
24% identity, 84% coverage of query (57.0 bits)
cdl / Q8L0X3 L-cysteine desulfhydrase (EC 4.4.1.1) from Fusobacterium nucleatum (see paper)
Q8L0X3 L-cysteine desulfidase (EC 4.4.1.28) from Fusobacterium nucleatum (see paper)
24% identity, 77% coverage of query (57.0 bits)
ThrC / b0004 threonine synthase (EC 4.2.3.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
thrC / P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (strain K12) (see 3 papers)
THRC_ECOLI / P00934 Threonine synthase; TS; EC 4.2.3.1 from Escherichia coli (strain K12) (see paper)
P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (see paper)
1vb3A / P00934 Crystal structure of threonine synthase from escherichia coli
thrC / GB|BAB96581.1 threonine synthase; EC 4.2.3.1 from Escherichia coli (see paper)
26% identity, 70% coverage of query (55.1 bits)
CBS / A0A563XPB1 cystathionine β-synthase (EC 4.2.1.22) from Gallus gallus (see 7 papers)
25% identity, 79% coverage of query (55.1 bits)
Q04513 threonine ammonia-lyase (EC 4.3.1.19) from Corynebacterium glutamicum (see paper)
26% identity, 82% coverage of query (54.7 bits)
8y1jA / Q9I6G0 Structure of the pyridoxal 5'-phosphate-dependent (plp) threonine deaminase ilva1 from pseudomonas aeruginosa pao1 (see paper)
27% identity, 82% coverage of query (54.7 bits)
uptG / AAK53485.1 cystathionine beta-lyase from Xanthomonas campestris pv. campestris (see 4 papers)
24% identity, 83% coverage of query (53.9 bits)
A0A220K8E3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus (see paper)
25% identity, 84% coverage of query (53.5 bits)
CBS1_CAEEL / G5EFH8 Cystathionine beta-synthase cbs-1; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Caenorhabditis elegans (see 2 papers)
25% identity, 82% coverage of query (52.8 bits)
5xemA / Q8RE94 Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-lanthionine-plp schiff base
22% identity, 84% coverage of query (50.1 bits)
5xenA Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-serine-plp schiff base
22% identity, 84% coverage of query (50.1 bits)
1A1D_PSEUD / Q00740 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Pseudomonas sp. (strain ACP) (see paper)
1rqxC / Q00740 Crystal structure of acc deaminase complexed with inhibitor (see paper)
25% identity, 83% coverage of query (49.3 bits)
1p5jA / P20132 Crystal structure analysis of human serine dehydratase (see paper)
24% identity, 73% coverage of query (45.1 bits)
SDS / P20132 L-serine dehydratase (EC 4.3.1.19; EC 4.3.1.17) from Homo sapiens (see 2 papers)
SDHL_HUMAN / P20132 L-serine dehydratase/L-threonine deaminase; SDH; L-serine deaminase; L-threonine dehydratase; TDH; EC 4.3.1.17; EC 4.3.1.19 from Homo sapiens (Human) (see 2 papers)
P20132 L-serine ammonia-lyase (EC 4.3.1.17) from Homo sapiens (see 3 papers)
24% identity, 73% coverage of query (43.5 bits)
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Lawrence Berkeley National Laboratory