Searching for up to 100 curated homologs for WP_011813057.1 NCBI__GCF_000015585.1:WP_011813057.1 (311 a.a.)
Found high-coverage hits (≥70%) to 90 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
nodI / GB|AAB16898.1 nodulation ATP-binding protein I from Rhizobium sp. N33 (see paper)
52% identity, 96% coverage of query (304 bits)
TC 3.A.1.102.1 / P50332 NodI, component of Lipooligosaccharide exporter (nodulation proteins, NodIJ) from Rhizobium galegae (see paper)
49% identity, 93% coverage of query (271 bits)
LNRL_BACSU / P94440 Linearmycin resistance ATP-binding protein LnrL; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 2 papers)
35% identity, 96% coverage of query (197 bits)
DRRA_STRPE / P32010 Daunorubicin/doxorubicin resistance ATP-binding protein DrrA; EC 7.6.2.- from Streptomyces peucetius (see 2 papers)
P32010 ABC-type xenobiotic transporter (EC 7.6.2.2) from Streptomyces peucetius (see paper)
TC 3.A.1.105.1 / P32010 DrrA, component of Daunorubicin, doxorubicin etc. (multidrug resistance) exporter, DrrAB from Streptomyces peucetius (see 2 papers)
40% identity, 95% coverage of query (196 bits)
sagG / GI|23305059 ABC transporter, ATP-binding protein SagG from Streptococcus iniae (see paper)
38% identity, 95% coverage of query (195 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
38% identity, 95% coverage of query (190 bits)
TC 3.A.1.105.8 / Q7UE58 ABC-type multidrug transport system, ATPase component, component of ABC-2 transporter from Rhodopirellula baltica (strain SH1)
37% identity, 97% coverage of query (179 bits)
TC 3.A.1.105.2 / Q53716 OleC4, component of Oleandomycin (drug resistance) exporter from Streptomyces antibioticus (see paper)
36% identity, 94% coverage of query (176 bits)
YadG / b0127 putative ABC transporter ATP-binding protein YadG from Escherichia coli K-12 substr. MG1655 (see 7 papers)
YADG_ECOLI / P36879 Uncharacterized ABC transporter ATP-binding protein YadG from Escherichia coli (strain K12) (see paper)
yadG / MB|P36879 uncharacterized ABC transporter ATP-binding protein yadG from Escherichia coli K12 (see paper)
40% identity, 72% coverage of query (169 bits)
TC 3.A.1.105.4 / Q4VWC9 PltI, component of The pyoluteorin (a chlorinated polyketide) efflux pump, PltHIJKN (see 2 papers)
41% identity, 74% coverage of query (164 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
38% identity, 77% coverage of query (158 bits)
8ee6A / Q8IZY2 Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
39% identity, 76% coverage of query (157 bits)
ABCA7_HUMAN / Q8IZY2 Phospholipid-transporting ATPase ABCA7; ABCA-SSN; ATP-binding cassette sub-family A member 7; Autoantigen SS-N; Macrophage ABC transporter; EC 7.6.2.1 from Homo sapiens (Human) (see 12 papers)
TC 3.A.1.211.10 / Q8IZY2 ABCA7. Regulates cellular efflux of phospholipids but not cholesterol, to apo A-1 from Homo sapiens (see 10 papers)
39% identity, 76% coverage of query (157 bits)
FLQE1_MYCTU / P9WQL7 Fluoroquinolones export ATP-binding protein Rv2688c; EC 7.6.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
36% identity, 98% coverage of query (156 bits)
TC 3.A.1.105.3 / Q70J75 CmrA, component of The 4A-4E-O-dideacetyl-chromomycin A3 (biosynthetic precursor of chromomycin) exporter (may also export chromomycin and mithramycin from Streptomyces griseus subsp. griseus
38% identity, 93% coverage of query (156 bits)
TC 3.A.1.211.3 / Q9BZC7 Multidrug resistance pump, ABCA2 (ABC2) from Homo sapiens (Human) (see 6 papers)
ABCA2 / GI|55962682 ATP-binding cassette sub-family A member 2 from Homo sapiens
38% identity, 78% coverage of query (155 bits)
ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
38% identity, 78% coverage of query (155 bits)
8eopA / Q8IZY2 Cryo-em structure of nanodisc reconstituted human abca7 eq mutant in atp bound closed state (see paper)
39% identity, 71% coverage of query (154 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
35% identity, 77% coverage of query (154 bits)
ABCA2_MOUSE / P41234 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Mus musculus (Mouse) (see 5 papers)
38% identity, 78% coverage of query (153 bits)
ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
39% identity, 74% coverage of query (152 bits)
YhiG / b3486 ribosome-associated ATPase from Escherichia coli K-12 substr. MG1655 (see 13 papers)
RBBA_ECOLI / P37624 Ribosome-associated ATPase; Ribosomal bound ATPase from Escherichia coli (strain K12) (see 5 papers)
yhiH / RF|YP_026225 uncharacterized ABC transporter ATP-binding protein yhiH from Escherichia coli K12 (see paper)
37% identity, 71% coverage of query (152 bits)
ABCAA_HUMAN / Q8WWZ4 ATP-binding cassette sub-family A member 10; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.17 / Q8WWZ4 ATP-binding cassette sub-family A member 10, ABCA10 of 1543 aas. May play a role in macrophage lipid homeostasis. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract. Down-regulated by cholesterol loading of macrophages from Homo sapiens
36% identity, 70% coverage of query (152 bits)
ABCA2_RAT / Q9ESR9 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Rattus norvegicus (Rat) (see 6 papers)
38% identity, 78% coverage of query (152 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
37% identity, 74% coverage of query (151 bits)
ABCAD_HUMAN / Q86UQ4 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
37% identity, 72% coverage of query (150 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
35% identity, 76% coverage of query (150 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
37% identity, 74% coverage of query (150 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
37% identity, 71% coverage of query (149 bits)
ABCA7_MOUSE / Q91V24 ATP-binding cassette sub-family A member 7 from Mus musculus (Mouse) (see 10 papers)
38% identity, 76% coverage of query (149 bits)
7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
35% identity, 86% coverage of query (149 bits)
7tbyA / O95477 The structure of human abca1 in nanodisc (see paper)
36% identity, 75% coverage of query (149 bits)
7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
37% identity, 71% coverage of query (148 bits)
7lkzA Structure of atp-bound human abca4
37% identity, 71% coverage of query (148 bits)
ABCA7_RAT / Q7TNJ2 ATP-binding cassette sub-family A member 7 from Rattus norvegicus (Rat) (see paper)
37% identity, 76% coverage of query (147 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
36% identity, 73% coverage of query (147 bits)
7tbwA / O95477 The structure of atp-bound abca1 (see paper)
37% identity, 70% coverage of query (137 bits)
CED7_CAEEL / P34358 ABC transporter ced-7; Cell death protein 7 from Caenorhabditis elegans (see paper)
TC 3.A.1.211.4 / P34358 The aced cell death 7 (ced-7) protein (translocates molecules that mediate adhesion between dying and engulfing embryonic cells during programmed death) from Caenorhabditis elegans (see 4 papers)
ced-7 / RF|NP_001021226.1 ABC transporter ced-7 from Caenorhabditis elegans
34% identity, 72% coverage of query (131 bits)
8dncA Cryoem structure of the a. Aeolicus wzmwzt transporter bound to the native o antigen and adp
30% identity, 77% coverage of query (125 bits)
8dkuA / O67181 Cryoem structure of the a. Aeolicus wzmwzt transporter bound to the native o antigen (see paper)
30% identity, 77% coverage of query (125 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
36% identity, 72% coverage of query (124 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
36% identity, 72% coverage of query (124 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
36% identity, 72% coverage of query (124 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
37% identity, 71% coverage of query (123 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
36% identity, 72% coverage of query (123 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
36% identity, 72% coverage of query (123 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
36% identity, 72% coverage of query (123 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
35% identity, 72% coverage of query (122 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
35% identity, 71% coverage of query (118 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
32% identity, 70% coverage of query (117 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
31% identity, 75% coverage of query (114 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
31% identity, 75% coverage of query (114 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
31% identity, 75% coverage of query (114 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
34% identity, 74% coverage of query (113 bits)
7ahhC Opua inhibited inward-facing, sbd docked
32% identity, 75% coverage of query (111 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
32% identity, 75% coverage of query (111 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
30% identity, 77% coverage of query (109 bits)
7ahdC Opua (e190q) occluded
32% identity, 71% coverage of query (109 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
31% identity, 77% coverage of query (104 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
30% identity, 77% coverage of query (103 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
30% identity, 77% coverage of query (103 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
30% identity, 77% coverage of query (103 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
30% identity, 77% coverage of query (103 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
30% identity, 77% coverage of query (103 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
30% identity, 77% coverage of query (103 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
30% identity, 77% coverage of query (103 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
32% identity, 83% coverage of query (102 bits)
Build an alignment for WP_011813057.1 and 67 homologs with ≥ 30% identity
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RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
28% identity, 72% coverage of query (101 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
33% identity, 71% coverage of query (97.4 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
31% identity, 73% coverage of query (95.5 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
30% identity, 73% coverage of query (94.7 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
30% identity, 72% coverage of query (92.0 bits)
8hprD Lpqy-sugabc in state 4
30% identity, 72% coverage of query (91.7 bits)
8hprC Lpqy-sugabc in state 4
30% identity, 72% coverage of query (91.7 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
30% identity, 70% coverage of query (90.9 bits)
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
30% identity, 74% coverage of query (90.5 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
28% identity, 74% coverage of query (89.4 bits)
2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
27% identity, 71% coverage of query (89.0 bits)
2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
27% identity, 71% coverage of query (89.0 bits)
3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
27% identity, 71% coverage of query (87.8 bits)
1xefA Crystal structure of the atp/mg2+ bound composite dimer of hlyb-nbd
27% identity, 71% coverage of query (85.1 bits)
8j5qD / P9WQJ5 Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
30% identity, 72% coverage of query (83.2 bits)
8j5tD Cryo-em structure of mycobacterium tuberculosis oppabcd in the catalytic intermediate state
29% identity, 74% coverage of query (82.0 bits)
8j5sD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- catalytic intermediate state
29% identity, 74% coverage of query (82.0 bits)
6xjhC Pmtcd abc exporter without the basket domain at c2 symmetry
23% identity, 74% coverage of query (81.6 bits)
7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
26% identity, 74% coverage of query (79.7 bits)
4s0fA Crystal structure of the peptidase-containing abc transporter pcat1 e648q mutant complexed with atpgs in an occluded conformation
26% identity, 74% coverage of query (78.6 bits)
DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
30% identity, 73% coverage of query (77.4 bits)
4fwiB / Q8RDH4 Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
30% identity, 73% coverage of query (77.4 bits)
5w81A / Q1LX78 Phosphorylated, atp-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (cftr) (see paper)
26% identity, 73% coverage of query (50.1 bits)
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