Searching for up to 100 curated homologs for WP_011813345.1 NCBI__GCF_000015585.1:WP_011813345.1 (416 a.a.)
Found high-coverage hits (≥70%) to 75 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6ndnA Crystal structure of selenocysteine lyase from escherichia coli
53% identity, 97% coverage of query (446 bits)
CsdB / b1680 L-cysteine desulfurase (EC 2.8.1.7; EC 4.4.1.16) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
sufS / P77444 L-cysteine desulfurase (EC 2.8.1.7; EC 4.4.1.16) from Escherichia coli (strain K12) (see 40 papers)
SUFS_ECOLI / P77444 Cysteine desulfurase; Cysteine sulfinate desulfinase; CSD; Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase; EC 2.8.1.7; EC 3.13.1.-; EC 4.4.1.16 from Escherichia coli (strain K12) (see 8 papers)
53% identity, 97% coverage of query (446 bits)
1kmkA E. Coli nifs/csdb protein at 2.20a with the cysteine perselenide intermediate (residue csz).
53% identity, 97% coverage of query (446 bits)
1i29A Crystal structure of csdb complexed with l-propargylglycine
53% identity, 97% coverage of query (446 bits)
5db5A Crystal structure of plp-bound e. Coli sufs (cysteine persulfide intermediate) in space group p21
53% identity, 97% coverage of query (445 bits)
6o13A E. Coli cysteine desulfurase sufs h123a with a cys-ketimine intermediate
53% identity, 97% coverage of query (442 bits)
6o11A E. Coli cysteine desulfurase sufs c364a with a cys-aldimine intermediate
53% identity, 97% coverage of query (442 bits)
SUFS_DICD3 / Q9EXP2 Cysteine desulfurase; Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase; EC 2.8.1.7; EC 4.4.1.16 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
sufS cysteine desulfurase; EC 2.8.1.7; EC 4.4.1.16 from Erwinia chrysanthemi str. 3937 (see 2 papers)
54% identity, 97% coverage of query (439 bits)
CYD_SYNE7 / Q8KUU5 Cysteine desulfurase; CyD; EC 2.8.1.7 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
50% identity, 96% coverage of query (424 bits)
CYD_MYCPA / Q9KII6 Probable cysteine desulfurase; EC 2.8.1.7 from Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10) (Mycobacterium paratuberculosis) (see paper)
51% identity, 97% coverage of query (420 bits)
7cepA / O32164 Crystal structure of l-cycloserine-bound form of cysteine desulfurase sufs from bacillus subtilis (see paper)
47% identity, 97% coverage of query (411 bits)
7xepA Sufs with l-propargylglycine
47% identity, 97% coverage of query (411 bits)
5zsoA Sufs from bacillus subtilis, soaked with l-cysteine for 90 sec
47% identity, 97% coverage of query (411 bits)
SUFS_BACSU / O32164 Cysteine desulfurase SufS; EC 2.8.1.7 from Bacillus subtilis (strain 168) (see 8 papers)
O32164 cysteine desulfurase (EC 2.8.1.7) from Bacillus subtilis (see 2 papers)
47% identity, 97% coverage of query (410 bits)
7xetA Sufs with beta-cyano-l-alanine
47% identity, 97% coverage of query (410 bits)
5xt6A A sulfur-transferring catalytic intermediate of sufs-sufu complex from bacillus subtilis
47% identity, 97% coverage of query (410 bits)
7ceoA Crystal structure of pmp-bound form of cysteine desulfurase sufs from bacillus subtilis
47% identity, 97% coverage of query (410 bits)
5j8qA Crystal structure of the cysteine desulfurase sufs of bacillus subtilis
47% identity, 97% coverage of query (410 bits)
7xekA Sufs with d-cysteine for 6 h
47% identity, 97% coverage of query (410 bits)
7xejA Sufs with d-cysteine for 5 min
47% identity, 97% coverage of query (410 bits)
7cerA Crystal structure of d-cycloserine-bound form of cysteine desulfurase sufs h121a from bacillus subtilis
47% identity, 97% coverage of query (407 bits)
Q8YU59 cysteine desulfurase (EC 2.8.1.7) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
47% identity, 96% coverage of query (399 bits)
SUFS_HALVD / D4GYV5 Cysteine desulfurase; Selenocysteine lyase; EC 2.8.1.7; EC 4.4.1.16 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
D4GYV5 cysteine desulfurase (EC 2.8.1.7); selenocysteine lyase (EC 4.4.1.16) from Haloferax volcanii (see paper)
45% identity, 97% coverage of query (389 bits)
7xenA Sufs with l-penicillamine
45% identity, 97% coverage of query (385 bits)
CNIF1_ARATH / Q93WX6 Cysteine desulfurase 1, chloroplastic; NIFS-like protein 1; CpNifS1; Plastid sufS-like protein; Protein AtCpNifS; Selenocysteine lyase; EC 2.8.1.7; EC 4.4.1.16 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q93WX6 cysteine desulfurase (EC 2.8.1.7) from Arabidopsis thaliana (see 2 papers)
47% identity, 96% coverage of query (381 bits)
8odqD / P9WQ69 Sufs-sufu complex from mycobacterium tuberculosis (see paper)
46% identity, 97% coverage of query (365 bits)
1t3iA / Q55793 Structure of slr0077/sufs, the essential cysteine desulfurase from synechocystis pcc 6803 (see paper)
45% identity, 96% coverage of query (364 bits)
YgdJ / b2810 cysteine sulfinate desulfinase from Escherichia coli K-12 substr. MG1655 (see 4 papers)
csdA / Q46925 cysteine sulfinate desulfinase from Escherichia coli (strain K12) (see 8 papers)
CSDA_ECOLI / Q46925 Cysteine desulfurase CsdA; Cysteine sulfinate desulfinase; CSD; Selenocysteine lyase; EC 2.8.1.7; EC 3.13.1.-; EC 4.4.1.16 from Escherichia coli (strain K12) (see 6 papers)
Q46925 cysteine desulfurase (EC 2.8.1.7) from Escherichia coli (see paper)
5ft8A / Q46925 Crystal structure of the complex between the cysteine desulfurase csda and the sulfur-acceptor csde in the persulfurated state at 2.50 angstroem resolution
csdA / GB|AAC75852.1 cysteine sulfinate desulfinase; EC 4.4.1.- from Escherichia coli K12 (see 5 papers)
42% identity, 96% coverage of query (323 bits)
7tlmA / C8W9P2 Structure of atopobium parvulum sufs (see paper)
40% identity, 96% coverage of query (315 bits)
6a6eA Crystal structure of thermostable cysteine desulfurase (fisufs) from thermophilic fervidobacterium islandicum aw-1 (see paper)
39% identity, 97% coverage of query (308 bits)
5b87A Crystal structure of a cysteine desulfurase from thermococcus onnurineus na1 in complex with alanine at 2.3 angstrom resolution
43% identity, 91% coverage of query (298 bits)
B6YT87 cysteine desulfurase (EC 2.8.1.7) from Thermococcus onnurineus (see paper)
43% identity, 91% coverage of query (297 bits)
5b7uA / B6YT87 Apo structure of cysteine desulfurase from thermococcus onnurineus na1 at 1.89a (see paper)
43% identity, 91% coverage of query (297 bits)
7tlpB Structure of atopobium parvulum sufs k235r
38% identity, 95% coverage of query (289 bits)
7tlpA / C8W9P2 Structure of atopobium parvulum sufs k235r (see paper)
38% identity, 95% coverage of query (288 bits)
Build an alignment for WP_011813345.1 and 35 homologs with ≥ 30% identity
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SUFS_PLABA / A0A509AF62 Putative cysteine desulfurase PbSufS; PbSufS; EC 2.8.1.7 from Plasmodium berghei (strain Anka) (see 2 papers)
28% identity, 94% coverage of query (208 bits)
SUFS_PLAVI / A0A2K8FTN3 Cysteine desulfurase SufS; PvSufS; EC 2.8.1.7 from Plasmodium vivax (see paper)
29% identity, 98% coverage of query (191 bits)
Q18BE4 cysteine desulfurase (EC 2.8.1.7) from Clostridioides difficile (see paper)
26% identity, 91% coverage of query (143 bits)
SUFS_PLAF7 / Q8IBT4 Cysteine desulfurase SufS; PfSufS; EC 2.8.1.7 from Plasmodium falciparum (isolate 3D7) (see 3 papers)
26% identity, 75% coverage of query (140 bits)
FGM3_GIBZE / A0A1C3YKE0 Aminotransferase-like protein FGM3; C64 cluster protein NRPS5; Fg3_54 cluster protein FGM3; Fusaoctaxin A biosynthesis cluster protein FGM3; EC 2.-.-.- from Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) (see 4 papers)
28% identity, 95% coverage of query (133 bits)
NFS1 / P25374 L-cysteine desulfurase (EC 2.8.1.7) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
NFS1_YEAST / P25374 Cysteine desulfurase, mitochondrial; tRNA-splicing protein SPL1; EC 2.8.1.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
29% identity, 90% coverage of query (132 bits)
MNIF1_ARATH / O49543 Cysteine desulfurase, mitochondrial; NIFS homolog 1; AtNFS1; AtNIFS1; Protein AtMtNifS; EC 2.8.1.7 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O49543 biotin synthase (EC 2.8.1.6); cysteine desulfurase (EC 2.8.1.7) from Arabidopsis thaliana (see 2 papers)
29% identity, 93% coverage of query (129 bits)
ISCS_RUMFL / O54055 Cysteine desulfurase IscS; EC 2.8.1.7 from Ruminococcus flavefaciens (see paper)
iscS / GI|2764753 cysteine desulfurase; EC 2.8.1.7 from Ruminococcus flavefaciens (see paper)
CAA05909.1 cysteine desulphurase from Ruminococcus flavefaciens (see paper)
27% identity, 84% coverage of query (127 bits)
NFS1 / Q9Y697 mitochondrial cysteine desulfurase NFS1 (EC 2.8.1.7) from Homo sapiens (see 5 papers)
NFS1_HUMAN / Q9Y697 Cysteine desulfurase; EC 2.8.1.7 from Homo sapiens (Human) (see 15 papers)
Q9Y697 cysteine desulfurase (EC 2.8.1.7) from Homo sapiens (see 2 papers)
28% identity, 92% coverage of query (127 bits)
6nzuA / Q9Y697 Structure of the human frataxin-bound iron-sulfur cluster assembly complex (see paper)
28% identity, 92% coverage of query (127 bits)
5zssA / A0A1I5NEH3 L-cysteine-plp reaction intermediate of nifs from hydrogenimonas thermophila
27% identity, 91% coverage of query (125 bits)
NFS1_MOUSE / Q9Z1J3 Cysteine desulfurase; m-Nfs1; EC 2.8.1.7 from Mus musculus (Mouse) (see 3 papers)
Q9Z1J3 cysteine desulfurase (EC 2.8.1.7) from Mus musculus (see paper)
29% identity, 84% coverage of query (124 bits)
USTD_ASPFN / B8NM72 Cysteine desulfurase-like protein ustD; Ustiloxin B biosynthesis protein D; EC 2.-.-.- from Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) (see 3 papers)
25% identity, 98% coverage of query (124 bits)
Q99P39 cysteine desulfurase (EC 2.8.1.7) from Rattus norvegicus (see paper)
28% identity, 90% coverage of query (123 bits)
NFS1_TRAHO / B0YLW6 Cysteine desulfurase, mitosomal; EC 2.8.1.7 from Trachipleistophora hominis (Microsporidian parasite) (see paper)
28% identity, 83% coverage of query (122 bits)
NFS1_CANAL / P87185 Cysteine desulfurase, mitochondrial; tRNA-splicing protein SPL1; EC 2.8.1.7 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
28% identity, 84% coverage of query (120 bits)
ISCS_AZOVI / O31269 Cysteine desulfurase IscS; EC 2.8.1.7 from Azotobacter vinelandii (see 2 papers)
26% identity, 88% coverage of query (115 bits)
O25008 cysteine desulfurase (EC 2.8.1.7) from Helicobacter pylori (see paper)
26% identity, 89% coverage of query (114 bits)
ISCSL_MYCTU / P9WQ71 IscS-like cysteine desulfurase; EC 2.8.1.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
31% identity, 89% coverage of query (114 bits)
NIFS_AZOVI / P05341 Cysteine desulfurase NifS; Nitrogenase metalloclusters biosynthesis protein NifS; EC 2.8.1.7 from Azotobacter vinelandii (see 2 papers)
26% identity, 89% coverage of query (113 bits)
5wt6A / O25008 Cysteine persulfide intermediate of nifs from helicobacter pylori
26% identity, 89% coverage of query (113 bits)
NuvC / b2530 cysteine desulfurase IscS (EC 2.8.1.7) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
iscS / P0A6B7 cysteine desulfurase IscS (EC 2.8.1.7) from Escherichia coli (strain K12) (see 2 papers)
ISCS_ECOLI / P0A6B7 Cysteine desulfurase IscS; NifS protein homolog; ThiI transpersulfidase; TusA transpersulfidase; EC 2.8.1.7 from Escherichia coli (strain K12) (see 11 papers)
ISCS_ECO57 / P0A6B9 Cysteine desulfurase IscS; EC 2.8.1.7 from Escherichia coli O157:H7 (see paper)
iscS cysteine desulfurase; EC 2.8.1.7 from Escherichia coli K12 (see 14 papers)
27% identity, 92% coverage of query (113 bits)
3lvmB / P0A6B9 Crystal structure of e.Coli iscs (see paper)
27% identity, 92% coverage of query (110 bits)
7xesA Nifs with l-penicillamine
26% identity, 87% coverage of query (110 bits)
7xeqA Nifs with d-cysteine
26% identity, 87% coverage of query (108 bits)
5wt2A Nifs from helicobacter pylori
26% identity, 87% coverage of query (108 bits)
ISCS2_ARCFU / O29689 Cysteine desulfurase IscS 2; EC 2.8.1.7 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 2 papers)
O29689 cysteine desulfurase (EC 2.8.1.7) from Archaeoglobus fulgidus (see paper)
26% identity, 89% coverage of query (108 bits)
1ecxB / Q9X218 Nifs-like protein (see paper)
24% identity, 91% coverage of query (108 bits)
5wt4A L-cysteine-plp intermediate of nifs from helicobacter pylori
26% identity, 87% coverage of query (107 bits)
7cetA Crystal structure of d-cycloserine-bound form of cysteine desulfurase nifs from helicobacter pylori
26% identity, 87% coverage of query (107 bits)
4eb5A / O29689 A. Fulgidus iscs-iscu complex structure (see paper)
26% identity, 89% coverage of query (107 bits)
4hvkA Crystal structure and functional studies of an unusual l-cysteine desulfurase from archaeoglobus fulgidus.
25% identity, 89% coverage of query (103 bits)
3a9yA / Q68FT9 Crystal structure of rat selenocysteine lyase in complex with l- cysteine (see paper)
27% identity, 90% coverage of query (100 bits)
SCLY_RAT / Q68FT9 Selenocysteine lyase; EC 4.4.1.16 from Rattus norvegicus (Rat) (see paper)
Q68FT9 selenocysteine lyase (EC 4.4.1.16) from Rattus norvegicus (see paper)
26% identity, 90% coverage of query (99.0 bits)
3a9zA Crystal structure of ras selenocysteine lyase in complex with selenopropionate
27% identity, 90% coverage of query (97.8 bits)
3a9xB Crystal structure of rat selenocysteine lyase
27% identity, 90% coverage of query (97.8 bits)
3gzcA / Q96I15 Structure of human selenocysteine lyase (see paper)
27% identity, 90% coverage of query (94.4 bits)
SCLY_HUMAN / Q96I15 Selenocysteine lyase; hSCL; EC 4.4.1.16 from Homo sapiens (Human) (see paper)
Q96I15 selenocysteine lyase (EC 4.4.1.16) from Homo sapiens (see 2 papers)
26% identity, 90% coverage of query (89.0 bits)
8irkA / A0R5M7 Carbon sulfoxide lyase
25% identity, 92% coverage of query (66.6 bits)
8is0A Carbon sulfoxide lyase - y106f
25% identity, 92% coverage of query (65.5 bits)
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Lawrence Berkeley National Laboratory