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Searching for up to 100 curated homologs for WP_011813685.1 NCBI__GCF_000015585.1:WP_011813685.1 (227 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

HP15_461 Histidinol-phosphatase (EC:3.1.3.15) from Marinobacter adhaerens HP15
    54% identity, 96% coverage of query (241 bits)

Psest_3864 Histidinol-phosphatase (EC:3.1.3.15) from Pseudomonas stutzeri RCH2
    54% identity, 96% coverage of query (235 bits)

HIS9_PSEAE / Q9I6F6 Histidinol-phosphatase; Hol-Pase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    55% identity, 96% coverage of query (234 bits)

BPHYT_RS03625 Histidinol-phosphatase (EC:3.1.3.15) from Burkholderia phytofirmans PsJN
    47% identity, 96% coverage of query (199 bits)

HIS9_NEIM8 / P0DV34 Histidinol-phosphatase; Hol-Pase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Neisseria meningitidis serogroup C (strain 8013) (see paper)
    43% identity, 95% coverage of query (196 bits)

SERB1_MYCTU / P9WGJ3 Phosphoserine phosphatase SerB1; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    32% identity, 96% coverage of query (87.4 bits)

Build an alignment

Build an alignment for WP_011813685.1 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

SERB2_MYCTU / O53289 Phosphoserine phosphatase SerB2; PSP; PSPase; O-phosphoserine phosphohydrolase; Protein-serine/threonine phosphatase; EC 3.1.3.3; EC 3.1.3.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
O53289 phosphoserine phosphatase (EC 3.1.3.3) from Mycobacterium tuberculosis (see 2 papers)
    25% identity, 88% coverage of query (53.9 bits)

SERB_STRCO / Q9S281 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    26% identity, 90% coverage of query (51.2 bits)

8a1zA / A0QJI1 Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea (see paper)
    27% identity, 88% coverage of query (50.4 bits)

SERB_MYCA1 / A0QJI1 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Mycobacterium avium (strain 104) (see paper)
    27% identity, 88% coverage of query (50.4 bits)

8a21A Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with phenylimidazole
    27% identity, 88% coverage of query (50.4 bits)

5jlpA Crystal structure of mycobacterium avium serb2 in complex with serine at act domain
    27% identity, 88% coverage of query (50.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory