Searching for up to 100 curated homologs for WP_011813795.1 NCBI__GCF_000015585.1:WP_011813795.1 (358 a.a.)
Found high-coverage hits (≥70%) to 37 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AroF / b2601 3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive (EC 2.5.1.54) from Escherichia coli K-12 substr. MG1655 (see 14 papers)
aroF / P00888 3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive (EC 2.5.1.54) from Escherichia coli (strain K12) (see 11 papers)
P00888 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Escherichia coli (see 2 papers)
55% identity, 99% coverage of query (418 bits)
6agmA / P00888 Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy- d-arabino-heptulosonate-7-phosphate synthase from escherichia coli (see paper)
54% identity, 98% coverage of query (397 bits)
aroF putative 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; EC 4.1.2.15 from Emericella nidulans (see paper)
52% identity, 95% coverage of query (352 bits)
5cksB Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase in complex with dahp oxime.
50% identity, 96% coverage of query (351 bits)
8e0sD Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase complexed with dahp oxime in unbound:(bound)2:unbound conformations
50% identity, 96% coverage of query (351 bits)
7rudB Dahp synthase complex with trifluoropyruvate oxime
50% identity, 96% coverage of query (351 bits)
AroG / b0754 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive (EC 2.5.1.54) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
aroG / P0AB91 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive (EC 2.5.1.54) from Escherichia coli (strain K12) (see 17 papers)
C3TIE2 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Escherichia coli (see 3 papers)
1kflA / P0AB91 Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase (dahp synthase) from e.Coli complexed with mn2+, pep, and phe (see paper)
50% identity, 96% coverage of query (350 bits)
AROG_SCHPO / Q9UT09 Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
48% identity, 97% coverage of query (350 bits)
P0AB91 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Escherichia coli (strain K12)
50% identity, 96% coverage of query (350 bits)
1gg1A Crystal structure analysis of dahp synthase in complex with mn2+ and 2-phosphoglycolate
50% identity, 96% coverage of query (350 bits)
1qr7A Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from escherichia coli complexed with pb2+ and pep
52% identity, 94% coverage of query (350 bits)
7rueA Dahp synthase complexed with trifluoropyruvate semicarbazone
50% identity, 96% coverage of query (346 bits)
5cksA Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase in complex with dahp oxime.
50% identity, 96% coverage of query (343 bits)
8e0sA Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase complexed with dahp oxime in unbound:(bound)2:unbound conformations
50% identity, 95% coverage of query (341 bits)
3tqkA / Q5NG89 Structure of phospho-2-dehydro-3-deoxyheptonate aldolase from francisella tularensis schu s4 (see paper)
49% identity, 91% coverage of query (340 bits)
7reuB / A0A2H0ZNV2 Crystal structure of aro4p, 3-deoxy-d-arabino-heptulosonate-7- phosphate (dahp) synthase from candida auris, l-tyr complex
46% identity, 95% coverage of query (337 bits)
1ofoA Crystal structure of the tyrosine regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with 2-phosphoglycolate
50% identity, 95% coverage of query (337 bits)
AMT16_ALTAL / C9K7C8 Phospho-2-dehydro-3-deoxyheptonate aldolase AMT16; AM-toxin biosynthesis protein 16; EC 2.5.1.54 from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
50% identity, 92% coverage of query (336 bits)
AROG_YEAST / P32449 Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
50% identity, 95% coverage of query (336 bits)
aroG phe-inhibited DAHP synthase; EC 4.1.2.15 from Emericella nidulans (see paper)
49% identity, 96% coverage of query (334 bits)
1of8A Double complex of the tyrosine sensitive dahp synthase from s. Cerevisiae with co2+, pep and the e4p analogoue g3p
51% identity, 93% coverage of query (333 bits)
1hfbA Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with phosphoenolpyruvate
50% identity, 93% coverage of query (330 bits)
4hsoA Crystal structure of s213g variant dah7ps from neisseria meningitidis
48% identity, 95% coverage of query (330 bits)
ARO4 / GB|AAB48240.1 phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; EC 2.5.1.54 from Candida albicans (see paper)
46% identity, 98% coverage of query (329 bits)
1of6A / P32449 Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with tyrosine and manganese
50% identity, 95% coverage of query (328 bits)
2-dehydro-3-deoxyphosphoheptonate aldolase / b1704 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive (EC 2.5.1.54) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
aroH / P00887 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive (EC 2.5.1.54) from Escherichia coli (strain K12) (see 9 papers)
46% identity, 95% coverage of query (328 bits)
Q9K169 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Neisseria meningitidis (see 3 papers)
48% identity, 95% coverage of query (328 bits)
5dcbC / Q9K169 Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated and complexed with pep
48% identity, 95% coverage of query (328 bits)
5dcdA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tyrosine)
48% identity, 95% coverage of query (328 bits)
5dceA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tryptophan)
48% identity, 95% coverage of query (327 bits)
4umbA Structural analysis of substrate-mimicking inhibitors in complex with neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
49% identity, 92% coverage of query (327 bits)
1ofrC Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with phenylalanine and manganese
50% identity, 95% coverage of query (327 bits)
4umcA Structural analysis of substrate-mimicking inhibitors in complex with neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
49% identity, 92% coverage of query (327 bits)
4umaA Structural analysis of substrate-mimicking inhibitors in complex with neisseria meningitidis 3 deoxy d arabino heptulosonate 7 phosphate synthase the importance of accommodating the active site water
49% identity, 92% coverage of query (327 bits)
AROF_YEAST / P14843 Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
48% identity, 93% coverage of query (324 bits)
P35170 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Corynebacterium glutamicum (see paper)
46% identity, 92% coverage of query (316 bits)
ARO3 3-Deoxy-D-arabinoheptulosonate-7-phosphate synthase from Candida albicans (see 2 papers)
51% identity, 72% coverage of query (259 bits)
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Lawrence Berkeley National Laboratory