Searching for up to 100 curated homologs for WP_011840249.1 NCBI__GCF_000015985.1:WP_011840249.1 (464 a.a.)
Found high-coverage hits (≥70%) to 65 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Psest_4288 Glutamate--putrescine ligase (EC 6.3.1.11) from Pseudomonas stutzeri RCH2
42% identity, 99% coverage of query (364 bits)
PfGW456L13_925 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens GW456-L13
41% identity, 99% coverage of query (361 bits)
AO353_08595 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2E3
41% identity, 99% coverage of query (360 bits)
AO356_13135 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2C3
41% identity, 99% coverage of query (359 bits)
PS417_27140 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas simiae WCS417
41% identity, 99% coverage of query (357 bits)
Pf1N1B4_2254 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N1B4
41% identity, 92% coverage of query (336 bits)
Pf6N2E2_4509 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2E2
41% identity, 92% coverage of query (333 bits)
BWI76_RS10710 Glutamate--putrescine ligase (EC 6.3.1.11) from Klebsiella michiganensis M5al
39% identity, 97% coverage of query (305 bits)
YcjK / b1297 glutamate-putrescine ligase (EC 6.3.1.11) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
puuA / P78061 glutamate-putrescine ligase (EC 6.3.1.11) from Escherichia coli (strain K12) (see 3 papers)
PUUA_ECOLI / P78061 Gamma-glutamylputrescine synthetase PuuA; Gamma-Glu-Put synthetase; Glutamate--putrescine ligase; EC 6.3.1.11 from Escherichia coli (strain K12) (see 3 papers)
puuA / BAD88705.1 gamma-glutamylputrescine synthetase from Escherichia coli K-12 (see paper)
38% identity, 97% coverage of query (300 bits)
BPHYT_RS23160 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Burkholderia phytofirmans PsJN
34% identity, 92% coverage of query (211 bits)
SO1268 Glutamate--putrescine ligase (EC 6.3.1.11) from Shewanella oneidensis MR-1
32% identity, 95% coverage of query (209 bits)
Build an alignment for WP_011840249.1 and 11 homologs with ≥ 30% identity
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ipuC / Q936T0 γ-glutamylisopropylamide synthetase from Pseudomonas sp. (see paper)
IPUC_PSESP / Q936T0 Glutamate--isopropylamine ligase; Gamma-glutamylisopropylamide synthetase; GIPA synthetase; EC 6.3.2.- from Pseudomonas sp. (see paper)
29% identity, 96% coverage of query (156 bits)
GLNA_THET8 / Q5SIP0 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
33% identity, 78% coverage of query (155 bits)
GLNA4_STRCO / O88070 Gamma-glutamylethanolamide synthetase GlnA4; EC 6.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 4 papers)
33% identity, 76% coverage of query (150 bits)
GLNA1_METMA / Q8PY99 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
Q8PY99 glutamine synthetase (EC 6.3.1.2) from Methanosarcina mazei (see paper)
30% identity, 81% coverage of query (148 bits)
8ufjB / Q8PY99 8ufjB (see paper)
30% identity, 81% coverage of query (148 bits)
8tfkA Glutamine synthetase
30% identity, 81% coverage of query (148 bits)
Q0E5H7 glutamine synthetase (EC 6.3.1.2) from Halobacillus halophilus (see paper)
29% identity, 76% coverage of query (147 bits)
P36205 glutamine synthetase (EC 6.3.1.2) from Thermotoga maritima (see paper)
28% identity, 82% coverage of query (147 bits)
P36687 glutamine synthetase (EC 6.3.1.2) from Pyrococcus woesei (see paper)
31% identity, 78% coverage of query (143 bits)
O33342 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis (see paper)
30% identity, 89% coverage of query (142 bits)
GLNA_THEKO / O08467 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
O08467 glutamine synthetase (EC 6.3.1.2) from Pyrococcus sp. (see paper)
30% identity, 78% coverage of query (135 bits)
8oooA Glutamine synthetase from methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and mgatp at 2.15 a resolution (see paper)
26% identity, 84% coverage of query (135 bits)
8ooqB Glutamine synthetase from Methanothermococcus thermolithotrophicus
26% identity, 84% coverage of query (135 bits)
GLNA2_STRCO / Q9RDS6 Gamma-glutamylpolyamine synthetase GlnA2; EC 6.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 3 papers)
31% identity, 78% coverage of query (134 bits)
gmas / B8EQ68 glutamate--methylamine ligase (EC 6.3.4.12) from Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) (see 2 papers)
30% identity, 80% coverage of query (134 bits)
A0R083 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
30% identity, 74% coverage of query (134 bits)
GLNA3_HALMT / I3R176 Glutamine synthetase 3; GS3; Glutamate--ammonia ligase; EC 6.3.1.2 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
B8ZJH0 glutamine synthetase (EC 6.3.1.2) from Haloferax mediterranei (see paper)
29% identity, 82% coverage of query (133 bits)
8ooxB / A0A832VZP6 8ooxB (see paper)
28% identity, 83% coverage of query (132 bits)
GLN1A_BACSU / P12425 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Bacillus subtilis (strain 168) (see 9 papers)
P12425 glutamine synthetase (EC 6.3.1.2) from Bacillus subtilis (see 2 papers)
29% identity, 78% coverage of query (131 bits)
4s0rD / P12425 Structure of gs-tnra complex (see paper)
29% identity, 78% coverage of query (131 bits)
P64246 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis variant bovis (see paper)
31% identity, 74% coverage of query (131 bits)
gmas / A9ZPH9 glutamate--methylamine ligase monomer (EC 6.3.4.12; EC 6.3.1.6) from Methylovorus mays (see 2 papers)
GMAS_METMY / A9ZPH9 Glutamate--methylamine ligase; Gamma-glutamylmethylamide synthetase; GMAS; Glutamate--ethylamine ligase; N(5)-ethyl-L-glutamine synthetase; Theanine synthetase; EC 6.3.4.12; EC 6.3.1.6 from Methylovorus mays (see 2 papers)
A9ZPH9 glutamate-methylamine ligase (EC 6.3.4.12) from Methylovorus mays (see paper)
27% identity, 76% coverage of query (131 bits)
4lnkA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of gs-glutamate-amppcp complex
29% identity, 78% coverage of query (131 bits)
4lniA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
29% identity, 78% coverage of query (131 bits)
P9WN37 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
31% identity, 74% coverage of query (131 bits)
F2RM17 glutamine synthetase (EC 6.3.1.2) from Haloferax mediterranei (see paper)
28% identity, 92% coverage of query (130 bits)
8oozA Glutamine synthetase
28% identity, 76% coverage of query (130 bits)
GLNA2_HALMT / I3R584 Gamma-glutamylputrescine synthetase; Gamma-Glu-Put synthetase; Glutamate--putrescine ligase; EC 6.3.1.11 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see 2 papers)
29% identity, 77% coverage of query (129 bits)
7tf9S / A0A5D5GA79 L. Monocytogenes gs(14)-q-glnr peptide (see paper)
28% identity, 74% coverage of query (128 bits)
7tdvC / E3VXC2 7tdvC (see paper)
27% identity, 76% coverage of query (128 bits)
7tf6A Glutamine synthetase
27% identity, 77% coverage of query (128 bits)
7tenA Glutamine synthetase
28% identity, 74% coverage of query (128 bits)
7tfaB / A0A0F0G8G2 7tfaB (see paper)
29% identity, 81% coverage of query (125 bits)
C7CGX7 glutamate-methylamine ligase (EC 6.3.4.12) from Methylorubrum extorquens (see paper)
31% identity, 81% coverage of query (124 bits)
7tdpA Structure of paenibacillus polymyxa gs bound to met-sox-p-adp (transition state complex) to 1.98 angstom
29% identity, 76% coverage of query (120 bits)
tdnQ / BAC82524.1 aniline dioxygenase from Frateuria sp. ANA-18 (see 3 papers)
28% identity, 91% coverage of query (119 bits)
GLNA_METJA / Q60182 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q60182 glutamine synthetase (EC 6.3.1.2) from Methanocaldococcus jannaschii (see paper)
27% identity, 76% coverage of query (119 bits)
5dm3C / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
31% identity, 72% coverage of query (117 bits)
7cqwA / A0A369R1N0 Gmas/adp complex-conformation 1 (see paper)
30% identity, 79% coverage of query (117 bits)
7cquA Gmas/adp/metsox-p complex
30% identity, 79% coverage of query (117 bits)
7cqqA Gmas in complex with amppnp and metsox
30% identity, 79% coverage of query (117 bits)
7cqnA Gmas in complex with amppcp
30% identity, 79% coverage of query (117 bits)
8wwuB / A0A7Y1Q2L1 8wwuB
27% identity, 91% coverage of query (115 bits)
8wwvA Glutamine synthetase
26% identity, 91% coverage of query (115 bits)
P0A9C5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Escherichia coli (strain K12)
29% identity, 73% coverage of query (104 bits)
1fpyA Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor phosphinothricin
29% identity, 73% coverage of query (103 bits)
1f1hA / P0A1P6 Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions (see paper)
29% identity, 73% coverage of query (103 bits)
GLN1B_SALTY / P0A1P6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
P0A1P6 glutamine synthetase (EC 6.3.1.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
glnA glutamate--ammonia ligase; EC 6.3.1.2 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
29% identity, 73% coverage of query (103 bits)
5dm3A / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
30% identity, 75% coverage of query (102 bits)
4s17A / A1A1Z1 The crystal structure of glutamine synthetase from bifidobacterium adolescentis atcc 15703
29% identity, 76% coverage of query (99.8 bits)
4xycA Nanomolar inhibitors of mycobacterium tuberculosis glutamine synthetase 1: synthesis, biological evaluation and x-ray crystallographic studies
27% identity, 75% coverage of query (96.7 bits)
4hppA / Q9HT65 Crystal structure of novel glutamine synthase homolog (see paper)
27% identity, 85% coverage of query (94.4 bits)
2lgsA Feedback inhibition of fully unadenylylated glutamine synthetase from salmonella typhimurium by glycine, alanine, and serine
28% identity, 73% coverage of query (93.2 bits)
1lgrA / P0A1P6 Interactions of nucleotides with fully unadenylylated glutamine synthetase from salmonella typhimurium (see paper)
28% identity, 73% coverage of query (93.2 bits)
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Lawrence Berkeley National Laboratory