Searching for up to 100 curated homologs for WP_011840384.1 NCBI__GCF_000015985.1:WP_011840384.1 (461 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8YFS0 threonine synthase (EC 4.2.3.1) from Brucella melitensis (see paper)
    60% identity, 100% coverage of query (558 bits)

4f4fA / Q8YFS0 X-ray crystal structure of plp bound threonine synthase from brucella melitensis
    60% identity, 100% coverage of query (558 bits)

thrC / AAF21130.1 threonine synthase from Methylobacillus flagellatus (see paper)
    44% identity, 99% coverage of query (351 bits)

THRC_YEAST / P16120 Threonine synthase; TS; EC 4.2.3.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P16120 threonine synthase (EC 4.2.3.1) from Saccharomyces cerevisiae (see paper)
    44% identity, 91% coverage of query (350 bits)

1kl7A / P16120 Crystal structure of threonine synthase from yeast (see paper)
    44% identity, 91% coverage of query (350 bits)

AgTHR4 / CAA62506.1 AgTHR4 from Eremothecium gossypii (see paper)
    43% identity, 99% coverage of query (349 bits)

Q2SWH9 threonine synthase (EC 4.2.3.1) from Burkholderia thailandensis (see paper)
    44% identity, 100% coverage of query (345 bits)

Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    43% identity, 91% coverage of query (338 bits)

THRC_CORGL / P23669 Threonine synthase; TS; EC 4.2.3.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    42% identity, 99% coverage of query (336 bits)

thrC / CAA82670.1 THREONINE SYNTHASE from Corynebacterium glutamicum (see paper)
    42% identity, 99% coverage of query (330 bits)

THNS2_HUMAN / Q86YJ6 Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT; EC 4.2.3.- from Homo sapiens (Human) (see paper)
    38% identity, 96% coverage of query (289 bits)

PerR / VIMSS78912 PerR regulator of Iron homeostasis; Manganese homeostasis; Oxidative stress response, effector Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide (repressor) from Lactococcus lactis subsp. lactis Il1403
    37% identity, 90% coverage of query (280 bits)

THNS2_MOUSE / Q80W22 Threonine synthase-like 2; TSH2; mTSH2; EC 4.2.3.- from Mus musculus (Mouse) (see paper)
    38% identity, 96% coverage of query (279 bits)

8g1yA / A0A0H2US33 Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
    38% identity, 91% coverage of query (263 bits)

thrC / CAA43214.1 threonine synthase from Serratia marcescens (see paper)
    35% identity, 94% coverage of query (246 bits)

ThrC / b0004 threonine synthase (EC 4.2.3.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
thrC / P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (strain K12) (see 3 papers)
THRC_ECOLI / P00934 Threonine synthase; TS; EC 4.2.3.1 from Escherichia coli (strain K12) (see paper)
P00934 threonine synthase (EC 4.2.3.1) from Escherichia coli (see paper)
1vb3A / P00934 Crystal structure of threonine synthase from escherichia coli
thrC / GB|BAB96581.1 threonine synthase; EC 4.2.3.1 from Escherichia coli (see paper)
    34% identity, 99% coverage of query (235 bits)

ABZR86_RS15975 threonine synthase (EC 4.2.3.1) from Dyella japonica UNC79MFTsu3.2
    33% identity, 99% coverage of query (208 bits)

Build an alignment

Build an alignment for WP_011840384.1 and 17 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    24% identity, 71% coverage of query (55.1 bits)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    24% identity, 81% coverage of query (54.7 bits)

2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
    23% identity, 71% coverage of query (47.8 bits)

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