Searching for up to 100 curated homologs for WP_011841694.1 NCBI__GCF_000015985.1:WP_011841694.1 (381 a.a.)
Found high-coverage hits (≥70%) to 30 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
para-aminobenzoate synthase component I / b1812 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
pabB / P05041 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 17 papers)
PABB_ECOLI / P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 8 papers)
pabB / RF|NP_416326.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Escherichia coli K12 (see 8 papers)
45% identity, 70% coverage of query (207 bits)
trpE / P20580 anthranilate synthase α subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TRPE_PSEAE / P20580 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P20580 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
43% identity, 72% coverage of query (197 bits)
pabAB / P32483 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces griseus (see 5 papers)
ADCS_STRGR / P32483 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoic acid synthase; PABA synthase; EC 2.6.1.85 from Streptomyces griseus (see paper)
44% identity, 71% coverage of query (191 bits)
1k0eA / P05041 The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
41% identity, 70% coverage of query (188 bits)
trpE / BAC65122.2 anthranilate synthase component I from Burkholderia multivorans (see paper)
40% identity, 72% coverage of query (184 bits)
ADCS / Q6TAS3 aminodeoxychorismate synthase (EC 2.6.1.85) from Solanum lycopersicum (see 2 papers)
ADCS_SOLLC / Q6TAS3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
39% identity, 74% coverage of query (177 bits)
trpE / Q06128 anthranilate synthase α subunit (EC 4.1.3.27) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
TRPE_SACS2 / Q06128 Anthranilate synthase component 1; AS; ASI; EC 4.1.3.27 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q06128 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Saccharolobus solfataricus (see paper)
37% identity, 72% coverage of query (161 bits)
trpE / AAA25223.1 anthranilate synthase alpha subunit from Lactococcus lactis (see paper)
32% identity, 83% coverage of query (157 bits)
1k0gA The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals
39% identity, 70% coverage of query (157 bits)
1k0gB / P05041 The crystal structure of aminodeoxychorismate synthase from phosphate grown crystals (see paper)
39% identity, 70% coverage of query (154 bits)
trpE / AAD09116.1 anthranilate synthase component I from Rhodobacter sphaeroides (see paper)
40% identity, 73% coverage of query (145 bits)
Q9AW95 anthranilate synthase (EC 4.1.3.27) from Catharanthus roseus (see paper)
32% identity, 71% coverage of query (124 bits)
Build an alignment for WP_011841694.1 and 12 homologs with ≥ 30% identity
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trpE anthranilate synthase component I; EC 4.1.3.27 from Leptospira biflexa serovar Patoc (see paper)
27% identity, 91% coverage of query (116 bits)
phnA / P09785 PhnA anthranilate synthase subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
PHNA_PSEAE / P09785 Anthranilate synthase component 1, pyocyanine specific; AS; ASI; Anthranilate synthase alpha subunit, pyocyanine specific; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P09785 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
33% identity, 70% coverage of query (113 bits)
3rv8C Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with cyclopropyl r-group
31% identity, 78% coverage of query (84.0 bits)
MBTI_MYCTU / P9WFX1 Salicylate synthase; Chorismate mutase; CM; Isochorismate synthase/isochorismate lyase; Mycobactin synthase protein; EC 5.4.99.5; EC 4.2.99.21; EC 5.4.4.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 8 papers)
P9WFX1 isochorismate lyase (EC 4.2.99.21); isochorismate synthase (EC 5.4.4.2) from Mycobacterium tuberculosis (see 2 papers)
31% identity, 78% coverage of query (83.2 bits)
8qc4A Salicylate synthase
31% identity, 78% coverage of query (83.2 bits)
3vehB / P9WFX1 Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor methylamt (see paper)
31% identity, 78% coverage of query (83.2 bits)
3logB Crystal structure of mbti from mycobacterium tuberculosis
31% identity, 78% coverage of query (83.2 bits)
6za5B M. Tuberculosis salicylate synthase mbti in complex with salicylate and mg2+
31% identity, 78% coverage of query (83.2 bits)
3st6A Structure of a m. Tuberculosis synthase, mbti, in complex with an isochorismate analogue inhibitor
31% identity, 78% coverage of query (83.2 bits)
2g5fA The structure of mbti from mycobacterium tuberculosis, the first enzyme in the synthesis of mycobactin, reveals it to be a salicylate synthase
31% identity, 78% coverage of query (83.2 bits)
6za4A M. Tuberculosis salicylate synthase mbti in complex with 5-(3- cyanophenyl)furan-2-carboxylate
30% identity, 78% coverage of query (78.2 bits)
3rv9A Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with ethyl r-group
31% identity, 78% coverage of query (75.5 bits)
3rv7A Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with isopropyl r-group
31% identity, 78% coverage of query (73.6 bits)
3rv6A Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with phenyl r-group
29% identity, 78% coverage of query (71.6 bits)
3rv8A Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with cyclopropyl r-group
30% identity, 78% coverage of query (71.2 bits)
3rv6B Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with phenyl r-group
29% identity, 78% coverage of query (66.2 bits)
3rv9C Structure of a m. Tuberculosis salicylate synthase, mbti, in complex with an inhibitor with ethyl r-group
30% identity, 78% coverage of query (65.9 bits)
6za4B / P9WFX1 M. Tuberculosis salicylate synthase mbti in complex with 5-(3- cyanophenyl)furan-2-carboxylate (see paper)
28% identity, 78% coverage of query (62.0 bits)
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Lawrence Berkeley National Laboratory