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Searching for up to 100 curated homologs for WP_011842332.1 NCBI__GCF_000015985.1:WP_011842332.1 (508 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

KGSD2_AZOBR / Q08IC0 Alpha-ketoglutaric semialdehyde dehydrogenase 2; alphaKGSA dehydrogenase 2; 2,5-dioxovalerate dehydrogenase 2; KGSADH-II; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IC0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
    55% identity, 98% coverage of query (485 bits)

Ga0059261_1896 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sphingomonas koreensis DSMZ 15582
    55% identity, 89% coverage of query (464 bits)

lhpG / Q88NF5 α-ketoglutaric semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    53% identity, 94% coverage of query (459 bits)

KGSD3_AZOBR / Q08IB7 Alpha-ketoglutaric semialdehyde dehydrogenase 3; alphaKGSA dehydrogenase 3; 2,5-dioxovalerate dehydrogenase 3; KGSADH-III; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IB7 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
    53% identity, 97% coverage of query (446 bits)

kgsD / Q9I1Q0 2-ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    52% identity, 98% coverage of query (437 bits)

ACIAD0131 / Q6FFQ0 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KGSDH_ACIAD / Q6FFQ0 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Acinetobacter baylyi (see paper)
    49% identity, 97% coverage of query (434 bits)

PS417_11015 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
    50% identity, 98% coverage of query (431 bits)

1eyyA / Q56694 Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
    49% identity, 93% coverage of query (424 bits)

aldH / AAA89078.1 fatty aldehyde dehydrogenase from Vibrio harveyi (see paper)
    49% identity, 93% coverage of query (424 bits)

HSERO_RS00735 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Herbaspirillum seropedicae SmR1
    51% identity, 89% coverage of query (421 bits)

Pf6N2E2_612 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N2E2
    49% identity, 98% coverage of query (413 bits)

Q88GW5 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Pseudomonas putida (see paper)
    52% identity, 87% coverage of query (411 bits)

SO0619 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Shewanella oneidensis MR-1
    30% identity, 82% coverage of query (108 bits)

Build an alignment

Build an alignment for WP_011842332.1 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Pf1N1B4_1109 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N1B4
    29% identity, 88% coverage of query (107 bits)

PS417_04200 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
    29% identity, 87% coverage of query (105 bits)

Ac3H11_612 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Acidovorax sp. GW101-3H11
    27% identity, 79% coverage of query (105 bits)

geoB / H1ZV37 geranial dehydrogenase (EC 1.2.1.3; EC 1.2.1.86) from Castellaniella defragrans (see 3 papers)
GEOB_CASD6 / H1ZV37 Geranial dehydrogenase; GaDH; Geraniol oxidation pathway protein B; Perillyl aldehyde dehydrogenase; EC 1.2.1.86 from Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen) (Alcaligenes defragrans) (see 2 papers)
    27% identity, 88% coverage of query (99.0 bits)

SM_b20891 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sinorhizobium meliloti 1021
    27% identity, 88% coverage of query (97.4 bits)

5u0mA Fatty aldehyde dehydrogenase from marinobacter aquaeolei vt8 and cofactor complex
    29% identity, 80% coverage of query (96.7 bits)

5u0lA / A1U5W8 X-ray crystal structure of fatty aldehyde dehydrogenase enzymes from marinobacter aquaeolei vt8 complexed with a substrate (see paper)
    29% identity, 80% coverage of query (96.7 bits)

Sama_3009 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Shewanella amazonensis SB2B
    29% identity, 82% coverage of query (96.3 bits)

tsaD / P94682 TsaD (EC 1.2.1.62) from Comamonas testosteroni (see paper)
TSAD1_COMTE / P94682 4-(hydroxymethyl)benzenesulfonate dehydrogenase TsaD1; Toluenesulfonate aldehyde dehydrogenase TsaD; EC 1.1.1.257 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
    29% identity, 94% coverage of query (95.5 bits)

2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
    28% identity, 90% coverage of query (93.6 bits)

SLAD_PSEPU / P0DOV9 3-sulfolactaldehyde dehydrogenase; SLA dehydrogenase; EC 1.2.1.97 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    30% identity, 81% coverage of query (93.2 bits)

KGSDH_BACSU / P42236 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Bacillus subtilis (strain 168) (see 2 papers)
    27% identity, 90% coverage of query (93.2 bits)

YdjU / b1746 aldehyde dehydrogenase (EC 1.2.1.71) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
astD / P76217 aldehyde dehydrogenase (EC 1.2.1.71) from Escherichia coli (strain K12) (see 6 papers)
ASTD_ECOLI / P76217 N-succinylglutamate 5-semialdehyde dehydrogenase; Succinylglutamic semialdehyde dehydrogenase; SGSD; EC 1.2.1.71 from Escherichia coli (strain K12) (see 3 papers)
P76217 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Escherichia coli (see paper)
astD / RF|NP_416260.1 N-succinylglutamate 5-semialdehyde dehydrogenase; EC 1.2.1.71 from Escherichia coli K12 (see 6 papers)
    29% identity, 79% coverage of query (93.2 bits)

SSDH_RAT / P51650 Succinate-semialdehyde dehydrogenase, mitochondrial; SSADH; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase; EC 1.2.1.24 from Rattus norvegicus (Rat) (see paper)
P51650 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Rattus norvegicus (see paper)
    27% identity, 89% coverage of query (93.2 bits)

4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
    26% identity, 87% coverage of query (92.4 bits)

Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
    26% identity, 87% coverage of query (92.4 bits)

ASTD_PSEAE / O50174 N-succinylglutamate 5-semialdehyde dehydrogenase; Succinylglutamic semialdehyde dehydrogenase; SGSD; EC 1.2.1.71 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
astD succinylglutamate-semialdehyde dehydrogenase; EC 1.2.1.71 from Pseudomonas aeruginosa (see paper)
    30% identity, 77% coverage of query (91.3 bits)

3ju8A / O50174 Crystal structure of succinylglutamic semialdehyde dehydrogenase from pseudomonas aeruginosa.
    30% identity, 77% coverage of query (91.3 bits)

AHGD_STRCO / Q9RKF1 3,6-anhydro-alpha-L-galactose dehydrogenase; AHG dehydrogenase; EC 1.2.1.92 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
Q9RKF1 3,6-anhydro-alpha-L-galactose dehydrogenase (EC 1.2.1.92) from Streptomyces coelicolor (see paper)
    27% identity, 89% coverage of query (90.1 bits)

gabD / Q4KKA2 NAD(P)-dependent succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    26% identity, 81% coverage of query (89.7 bits)

A0A0F4THK8 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Pseudomonas fluorescens (see paper)
    27% identity, 84% coverage of query (89.0 bits)

xacF / D4GP41 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see paper)
KGSDH_HALVD / D4GP41 Alpha-ketoglutarate semialdehyde dehydrogenase; KGSADH; EC 1.2.1.26 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    29% identity, 89% coverage of query (89.0 bits)

A0A0A7PB40 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Sphingopyxis fribergensis (see paper)
    27% identity, 88% coverage of query (89.0 bits)

xylA / A0A0H3C801 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 6 papers)
    29% identity, 94% coverage of query (87.8 bits)

AO353_11505 succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens FW300-N2E3
    27% identity, 84% coverage of query (87.8 bits)

4u3wA / B4EFS9 X-ray crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase from burkholderia cenocepacia
    32% identity, 76% coverage of query (87.4 bits)

N0DT23 4-trimethylammoniobutyraldehyde dehydrogenase (EC 1.2.1.47) from Pseudomonas sp. (see paper)
    27% identity, 87% coverage of query (87.4 bits)

padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
    28% identity, 83% coverage of query (85.9 bits)

AldH / b1300 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
puuC / P23883 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli (strain K12) (see 6 papers)
PUUC_ECOLI / P23883 NADP/NAD-dependent aldehyde dehydrogenase PuuC; ALDH; 3-hydroxypropionaldehyde dehydrogenase; Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase; EC 1.2.1.5 from Escherichia coli (strain K12) (see 2 papers)
P23883 4-(gamma-glutamylamino)butanal dehydrogenase (EC 1.2.1.99) from Escherichia coli (see 3 papers)
puuC / BAD88708.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase from Escherichia coli K-12 (see paper)
    28% identity, 87% coverage of query (84.3 bits)

Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
    25% identity, 88% coverage of query (84.3 bits)

YdbG / b1385 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
feaB / P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (strain K12) (see 10 papers)
P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (see 3 papers)
    28% identity, 83% coverage of query (84.0 bits)

A6T8Z5 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Klebsiella pneumoniae (see paper)
    28% identity, 81% coverage of query (84.0 bits)

4yweA / B4E8B7 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
    27% identity, 94% coverage of query (83.6 bits)

Q88RC0 glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas putida (see 2 papers)
    27% identity, 81% coverage of query (83.6 bits)

cnbD / Q38M39 2-aminomuconate semialdehyde dehydrogenase (EC 1.2.1.32) from Comamonas testosteroni CNB-1 (see paper)
    29% identity, 81% coverage of query (83.6 bits)

TGNE_ACIAD / Q6F9G0 Succinate semialdehyde dehydrogenase; SSA dehydrogenase; EC 1.2.1.24 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    26% identity, 85% coverage of query (82.4 bits)

PfGW456L13_1974 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Pseudomonas fluorescens GW456-L13
    28% identity, 88% coverage of query (82.0 bits)

7w5nA / Q47943 The crystal structure of the reduced form of gluconobacter oxydans wsh-004 sndh (see paper)
    27% identity, 87% coverage of query (80.9 bits)

ADH1A_MAIZE / C0P9J6 Aminoaldehyde dehydrogenase 1a; ZmAMADH1a; 4-trimethylammoniobutyraldehyde dehydrogenase AMADH1a; Aminobutyraldehyde dehydrogenase AMADH1a; Betaine aldehyde dehydrogenase AMADH1a; Gamma-guanidinobutyraldehyde dehydrogenase AMADH1a; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8; EC 1.2.1.54 from Zea mays (Maize) (see 2 papers)
C0P9J6 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Zea mays (see paper)
    26% identity, 76% coverage of query (80.9 bits)

4i8pA / C0P9J6 Crystal structure of aminoaldehyde dehydrogenase 1a from zea mays (zmamadh1a) (see paper)
    26% identity, 76% coverage of query (80.9 bits)

BADH2_ORYSI / B3VMC0 Betaine aldehyde dehydrogenase 2; BADH 2; EC 1.2.1.8 from Oryza sativa subsp. indica (Rice) (see paper)
BADH2_ORYSJ / Q84LK3 Betaine aldehyde dehydrogenase 2; OsBADH2; EC 1.2.1.8 from Oryza sativa subsp. japonica (Rice) (see 6 papers)
B3VMC0 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Oryza sativa (see paper)
Q84LK3 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Oryza sativa (see 2 papers)
    25% identity, 76% coverage of query (79.7 bits)

BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
    24% identity, 87% coverage of query (77.8 bits)

7w5kA The c296a mutant of l-sorbosone dehydrogenase (sndh) from gluconobacter oxydans wsh-004
    27% identity, 87% coverage of query (77.8 bits)

8rwkA / P46367 Cryoem structure of the central ald4 filament determined by filamentid (see paper)
    28% identity, 84% coverage of query (77.8 bits)

8hapB Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii
    24% identity, 83% coverage of query (77.4 bits)

8hapA / Q976X5 Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii (see paper)
    24% identity, 83% coverage of query (77.4 bits)

8of1A / A0A2K1ICJ7 Structure of aldh5f1 from moss physcomitrium patens in complex with NAD+ in the contracted conformation
    26% identity, 83% coverage of query (77.4 bits)

4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
    27% identity, 81% coverage of query (77.4 bits)

3u4jA / Q930S8 Crystal structure of NAD-dependent aldehyde dehydrogenase from sinorhizobium meliloti
    28% identity, 77% coverage of query (75.9 bits)

4v37A / P17202 Crystal structure of betaine aldehyde dehydrogenase from spinach showing a thiohemiacetal with 3-aminopropionaldehyde
    24% identity, 87% coverage of query (75.1 bits)

4f3xA / Q92ND9 Crystal structure of putative aldehyde dehydrogenase from sinorhizobium meliloti 1021 complexed with NAD
    27% identity, 83% coverage of query (73.6 bits)

4itbA / B1XMM6 Structure of bacterial enzyme in complex with cofactor and substrate (see paper)
    27% identity, 84% coverage of query (71.6 bits)

6fkuA / Q72KD3 Structure and function of aldehyde dehydrogenase from thermus thermophilus: an enzyme with an evolutionarily-distinct c-terminal arm (recombinant protein with shortened c-terminal, in complex with NADP) (see paper)
    26% identity, 77% coverage of query (70.5 bits)

VDH_CORGL / Q8NMB0 Vanillin dehydrogenase; Aromatic aldehyde dehydrogenase; EC 1.2.1.67; EC 1.2.1.64; EC 1.2.1.96 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
Q8NMB0 vanillin dehydrogenase (EC 1.2.1.67) from Corynebacterium glutamicum (see paper)
    25% identity, 83% coverage of query (68.9 bits)

3efvA / Q8ZPI3 Crystal structure of a putative succinate-semialdehyde dehydrogenase from salmonella typhimurium lt2 with bound NAD (see paper)
    27% identity, 85% coverage of query (68.6 bits)

gapN / Q59931 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase subunit (EC 1.2.1.9) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see 3 papers)
GAPN_STRMU / Q59931 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)]; Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase; Triosephosphate dehydrogenase; EC 1.2.1.9 from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see 3 papers)
gapN / GB|AAN58410.1 glyceraldehyde-3-phosphate dehydrogenase (NADP+); EC 1.2.1.9 from Streptococcus mutans (see paper)
    24% identity, 83% coverage of query (67.8 bits)

4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
    26% identity, 72% coverage of query (67.4 bits)

3vz3A Structural insights into substrate and cofactor selection by sp2771
    27% identity, 84% coverage of query (67.4 bits)

3rhhD / Q9KAQ0 Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from bacillus halodurans c-125 complexed with NADP
    26% identity, 82% coverage of query (67.4 bits)

ALDH8A1 / Q9H2A2 aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
AL8A1_HUMAN / Q9H2A2 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; Aldehyde dehydrogenase family 8 member A1; EC 1.2.1.32 from Homo sapiens (Human) (see 2 papers)
Q9H2A2 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
    24% identity, 75% coverage of query (66.6 bits)

mmsA / P42412 (methyl)malonate-semialdehyde dehydrogenase monomer (EC 1.2.1.27; EC 1.2.1.18) from Bacillus subtilis (strain 168) (see 4 papers)
IOLA_BACSU / P42412 Malonate-semialdehyde dehydrogenase; MSA dehydrogenase; Methylmalonate-semialdehyde dehydrogenase; MMSA dehydrogenase; MMSDH; MSDH; EC 1.2.1.27 from Bacillus subtilis (strain 168) (see 5 papers)
P42412 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Bacillus subtilis (see paper)
    24% identity, 80% coverage of query (66.2 bits)

1t90A / P42412 Crystal structure of methylmalonate semialdehyde dehydrogenase from bacillus subtilis
    24% identity, 80% coverage of query (66.2 bits)

5ur2B / Q6MNK1 Crystal structure of proline utilization a (puta) from bdellovibrio bacteriovorus inactivated by n-propargylglycine (see paper)
    26% identity, 86% coverage of query (65.9 bits)

1qi1B Ternary complex of an NADP dependent aldehyde dehydrogenase
    24% identity, 83% coverage of query (65.9 bits)

6s6wA Crystal structure of human aldh1a3 in complex with 2,6- diphenylimidazo[1,2-a]pyridine (compound ga11) and NAD+
    26% identity, 87% coverage of query (65.1 bits)

2esdA / Q59931 Crystal structure of thioacylenzyme intermediate of an NADP dependent aldehyde dehydrogenase (see paper)
    24% identity, 83% coverage of query (65.1 bits)

6popA Crystal structure of daua in complex with NADP+ (see paper)
    23% identity, 82% coverage of query (63.5 bits)

2opxA Crystal structure of lactaldehyde dehydrogenase from escherichia coli
    26% identity, 76% coverage of query (63.2 bits)

4pxlA / Q8S532 Structure of zm aldh2-3 (rf2c) in complex with NAD (see paper)
    26% identity, 83% coverage of query (62.4 bits)

6tryA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with mf13 inhibitor compound
    26% identity, 81% coverage of query (62.0 bits)

6te5B Crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
    26% identity, 81% coverage of query (62.0 bits)

3b4wA / P96405 Crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+
    25% identity, 72% coverage of query (60.1 bits)

7qk9A Crystal structure of the aldh1a3-atp complex
    25% identity, 87% coverage of query (59.3 bits)

ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
    25% identity, 87% coverage of query (59.3 bits)

7a6qB Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound
    25% identity, 87% coverage of query (59.3 bits)

7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
    25% identity, 87% coverage of query (59.3 bits)

5fhzA Human aldehyde dehydrogenase 1a3 complexed with NAD(+) and retinoic acid
    25% identity, 87% coverage of query (59.3 bits)

6tgwA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor
    26% identity, 81% coverage of query (58.9 bits)

ALD6 / P54115 magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.4) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ALDH6_YEAST / P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic; Mg(2+)-activated acetaldehyde dehydrogenase; Mg(2+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P54115 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Saccharomyces cerevisiae (see 2 papers)
    24% identity, 85% coverage of query (57.4 bits)

4pxnA / C0PHD8 Structure of zm aldh7 in complex with NAD (see paper)
    24% identity, 75% coverage of query (56.2 bits)

3iwkH / Q8VWZ1 Crystal structure of aminoaldehyde dehydrogenase 1 from pisum sativum (psamadh1) (see paper)
    25% identity, 76% coverage of query (55.1 bits)

AADH1_PEA / Q8VWZ1 Aminoaldehyde dehydrogenase 1, peroxisomal; PsAMADH1; Aminobutyraldehyde dehydrogenase AMADH1; Gamma-guanidinobutyraldehyde dehydrogenase AMADH1; EC 1.2.1.-; EC 1.2.1.19; EC 1.2.1.54 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
Q8VWZ1 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Pisum sativum (see 3 papers)
    25% identity, 76% coverage of query (54.7 bits)

2eiwA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-proline
    25% identity, 83% coverage of query (53.5 bits)

1ad3A / P11883 Class 3 aldehyde dehydrogenase complex with nicotinamide-adenine- dinucleotide (see paper)
    23% identity, 72% coverage of query (51.2 bits)

3iwjA / Q93YB2 Crystal structure of aminoaldehyde dehydrogenase 2 from pisum sativum (psamadh2) (see paper)
    23% identity, 76% coverage of query (51.2 bits)

AADH2_PEA / Q93YB2 Aminoaldehyde dehydrogenase 2, peroxisomal; PsAMADH2; Aminobutyraldehyde dehydrogenase AMADH2; Gamma-guanidinobutyraldehyde dehydrogenase AMADH2; EC 1.2.1.-; EC 1.2.1.19; EC 1.2.1.54 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see 2 papers)
Q93YB2 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Pisum sativum (see 2 papers)
    23% identity, 76% coverage of query (51.2 bits)

O14293 Putative aldehyde dehydrogenase-like protein C9E9.09c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    24% identity, 81% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory