Searching for up to 100 curated homologs for WP_011869215.1 NCBI__GCF_000016125.1:WP_011869215.1 (427 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5i92F / P48247 Crystal structure of glutamate-1-semialdehyde 2,1- aminomutase (gsa) from pseudomonas aeruginosa
49% identity, 98% coverage of query (427 bits)
P30949 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Bacillus subtilis (see paper)
hemL / AAA22515.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus subtilis (see 2 papers)
49% identity, 97% coverage of query (426 bits)
3bs8A / P30949 Crystal structure of glutamate 1-semialdehyde aminotransferase complexed with pyridoxamine-5'-phosphate from bacillus subtilis (see paper)
49% identity, 97% coverage of query (425 bits)
hemL / CAD48149.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus megaterium (see paper)
49% identity, 98% coverage of query (422 bits)
3k28A / Q81LD0 Crystal structure of a glutamate-1-semialdehyde aminotransferase from bacillus anthracis with bound pyridoxal 5'phosphate
49% identity, 99% coverage of query (417 bits)
P24630 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Synechococcus sp. (see 2 papers)
48% identity, 99% coverage of query (413 bits)
GSA2_ARATH / Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
49% identity, 99% coverage of query (412 bits)
3fqaA Gabaculien complex of gabaculine resistant gsam version
48% identity, 99% coverage of query (410 bits)
2gsaB Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
47% identity, 99% coverage of query (409 bits)
2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
47% identity, 99% coverage of query (409 bits)
3fq7A / P24630 Gabaculine complex of gsam (see paper)
47% identity, 99% coverage of query (408 bits)
GSA1 / P42799 glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
GSA1_ARATH / P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P42799 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
47% identity, 99% coverage of query (408 bits)
3usfA Crystal structure of dava-4
47% identity, 99% coverage of query (408 bits)
2hp2A Inter-subunit signaling in gsam
47% identity, 99% coverage of query (408 bits)
2hp1A Inter-subunit signaling in gsam
47% identity, 99% coverage of query (408 bits)
2hozA Inter-subunit signaling in gsam
47% identity, 99% coverage of query (408 bits)
5hdmA / P42799 Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase (see paper)
47% identity, 99% coverage of query (407 bits)
5hdmB Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase
47% identity, 99% coverage of query (407 bits)
GSA_SACS2 / Q980U5 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q980U5 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Saccharolobus solfataricus (see paper)
48% identity, 96% coverage of query (400 bits)
6w80A / B2FT35 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from stenotrophomonas maltophilia k279a in complex with plp
46% identity, 97% coverage of query (399 bits)
Gsa / b0154 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
hemL / P23893 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli (strain K12) (see 19 papers)
GSA_ECOLI / P23893 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Escherichia coli (strain K12) (see 3 papers)
46% identity, 99% coverage of query (397 bits)
hemL / P0CL07 glutamate-1-semialdehyde 2,1-aminomutase subunit (EC 5.4.3.8) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
46% identity, 99% coverage of query (395 bits)
2e7uA / Q5SJS4 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from thermus thermophilus hb8
45% identity, 98% coverage of query (394 bits)
2zsmA / Q9Y9I9 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from aeropyrum pernix, hexagonal form
42% identity, 98% coverage of query (369 bits)
3usfB / Q31QJ2 Crystal structure of dava-4
44% identity, 99% coverage of query (366 bits)
2hp1B Inter-subunit signaling in gsam
43% identity, 99% coverage of query (361 bits)
Q8NT73 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Corynebacterium glutamicum (see paper)
42% identity, 96% coverage of query (339 bits)
hemL / BAA21914.1 glutamate 1-semialdehyde 2,1-aminomutase from Propionibacterium freudenreichii (see 2 papers)
39% identity, 98% coverage of query (320 bits)
2cfbA / Q8DLK8 Glutamate-1-semialdehyde 2,1-aminomutase from thermosynechococcus elongatus (see paper)
39% identity, 92% coverage of query (304 bits)
D1C218 beta-alanine-pyruvate transaminase (EC 2.6.1.18) from Sphaerobacter thermophilus (see paper)
34% identity, 93% coverage of query (268 bits)
6k8hB / D1C218 Crystal structure of an omega-transaminase from sphaerobacter thermophilus (see paper)
34% identity, 93% coverage of query (268 bits)
4zm4B / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
33% identity, 96% coverage of query (258 bits)
4zm4D / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
38% identity, 73% coverage of query (243 bits)
6ssdA Transaminase with plp bound (see paper)
31% identity, 93% coverage of query (225 bits)
6ssgA Transaminase with dcs bound
31% identity, 93% coverage of query (225 bits)
6ssfA Transaminase with lcs bound
31% identity, 93% coverage of query (225 bits)
6sseA Transaminase with pmp bound
31% identity, 93% coverage of query (225 bits)
KAT_CLOAI / B0VH76 3-aminobutyryl-CoA aminotransferase; HemL-like protein; EC 2.6.1.111 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VH76 3-aminobutanoyl-CoA transaminase (EC 2.6.1.111) from Candidatus Cloacimonas acidaminovorans (see paper)
33% identity, 98% coverage of query (222 bits)
2ykuA / A3EYF7 Structural determinants of the beta-selectivity of a bacterial aminotransferase (see paper)
30% identity, 89% coverage of query (208 bits)
4ao4A Structural determinants of the beta-selectivity of a bacterial aminotransferase
30% identity, 89% coverage of query (208 bits)
2ykyA Structural determinants of the beta-selectivity of a bacterial aminotransferase
30% identity, 89% coverage of query (208 bits)
2ykxA Structural determinants of the beta-selectivity of a bacterial aminotransferase
30% identity, 89% coverage of query (208 bits)
2ykvA Structural determinants of the beta-selectivity of a bacterial aminotransferase
30% identity, 89% coverage of query (208 bits)
bmyA / CAE11250.1 BmyA protein from Bacillus amyloliquefaciens (see paper)
32% identity, 92% coverage of query (207 bits)
4ao9A / H8WR05 Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus (see paper)
32% identity, 96% coverage of query (206 bits)
BFAT_VARPD / H8WR05 Beta-phenylalanine transaminase; Aromatic beta-amino acid aminotransferase; Beta-phenylalanine aminotransferase; VpAT; EC 2.6.1.- from Variovorax paradoxus (see paper)
H8WR05 tyrosine transaminase (EC 2.6.1.5) from Variovorax paradoxus (see paper)
32% identity, 96% coverage of query (206 bits)
4aoaA Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from variovorax paradoxus
32% identity, 96% coverage of query (206 bits)
6kfuA / Q9R9J1 A acp-amt fusion protein of hybrid polyketide/non-ribosomal peptide synthetase
32% identity, 92% coverage of query (199 bits)
MYCA_BACIU / Q9R9J1 Mycosubtilin synthase subunit A; EC 2.3.1.- from Bacillus subtilis (see paper)
32% identity, 92% coverage of query (199 bits)
6kfrA Amino-transferase (amt) domain - arg complex of hybrid polyketide/non- ribosomal peptide synthetase
32% identity, 92% coverage of query (199 bits)
gdnH / K4JEW9 guadinomine polyketide synthase module 4 from Streptomyces sp. K01-0509 (see paper)
30% identity, 93% coverage of query (194 bits)
YC7B_SCHPO / O94492 Uncharacterized aminotransferase C417.11c; EC 2.6.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 91% coverage of query (175 bits)
Build an alignment for WP_011869215.1 and 52 homologs with ≥ 30% identity
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mxcL / Q9F631 myxocheline aldehyde aminotransferase from Stigmatella aurantiaca (see 2 papers)
27% identity, 97% coverage of query (172 bits)
6hbvA / D2D3B2 Structure of plp internal aldimine form of sphingopyxis sp. Mta144 fumi protein
27% identity, 98% coverage of query (159 bits)
fumI / D2D3B2 aminopentol aminotransferase from Sphingopyxis macrogoltabida (see paper)
FUMI_SPHMC / D2D3B2 Aminopentol aminotransferase; EC 2.6.1.- from Sphingopyxis macrogoltabida (Sphingomonas macrogoltabidus) (see 2 papers)
27% identity, 98% coverage of query (159 bits)
A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
35% identity, 73% coverage of query (154 bits)
ORNAT_THEKO / Q5JEW1 Ornithine aminotransferase; Orn-AT; Lysine aminotransferase; Lys-AT; EC 2.6.1.13; EC 2.6.1.36 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
31% identity, 80% coverage of query (150 bits)
GabT / b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
gabT / P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12) (see 28 papers)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12) (see 6 papers)
29% identity, 86% coverage of query (147 bits)
8ht4B / Q59282 Crystal structure of acetylornithine aminotransferase complex with plp from corynebacterium glutamicum (see paper)
33% identity, 72% coverage of query (147 bits)
davT / Q9I6M4 5-aminovalerate aminotransferase (EC 2.6.1.48) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
DAVT_PSEAE / Q9I6M4 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6M4 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas aeruginosa (see paper)
32% identity, 77% coverage of query (147 bits)
1sf2A / P22256 Structure of e. Coli gamma-aminobutyrate aminotransferase (see paper)
29% identity, 86% coverage of query (145 bits)
1szkA The structure of gamma-aminobutyrate aminotransferase mutant: e211s
29% identity, 86% coverage of query (145 bits)
1sffA Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
29% identity, 86% coverage of query (145 bits)
7vnoA / O50131 Structure of aminotransferase (see paper)
29% identity, 83% coverage of query (143 bits)
ORNAT_PYRHO / O50131 Ornithine aminotransferase; Orn-AT; Ornithine delta-aminotransferase; EC 2.6.1.13 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
29% identity, 83% coverage of query (143 bits)
7vo1A Structure of aminotransferase-substrate complex
29% identity, 83% coverage of query (143 bits)
7vntA Structure of aminotransferase-substrate complex
29% identity, 83% coverage of query (143 bits)
gabT / Q4KKA1 4-aminobutyrate transaminase subunit (EC 2.6.1.19) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
31% identity, 77% coverage of query (139 bits)
slr1022 / P73133 bifunctional acetylornithine transaminase/4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19; EC 2.6.1.11) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 4 papers)
ARGD_SYNY3 / P73133 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
P73133 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 6803 (see paper)
30% identity, 74% coverage of query (134 bits)
GoaG / b1302 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
puuE / P50457 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli (strain K12) (see 11 papers)
PUUE_ECOLI / P50457 4-aminobutyrate aminotransferase PuuE; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; EC 2.6.1.19 from Escherichia coli (strain K12) (see 2 papers)
puuE / BAD88710.1 gamma-aminobutyrate aminotransferase from Escherichia coli K-12 (see paper)
29% identity, 77% coverage of query (134 bits)
4ysnC / M1GRN3 Structure of aminoacid racemase in complex with plp (see paper)
30% identity, 74% coverage of query (130 bits)
5yktA / Q9HWU0 Crystal structure of a glutamate-1-semialdehyde-aminomutase (k286a) from pseudomonas aeruginosa pao1 in complex with pmp (see paper)
25% identity, 91% coverage of query (130 bits)
Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
29% identity, 80% coverage of query (127 bits)
2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
29% identity, 80% coverage of query (127 bits)
5wyaA Structure of amino acid racemase, 2.65 a
29% identity, 73% coverage of query (127 bits)
5wyfA Structure of amino acid racemase, 2.12 a
29% identity, 73% coverage of query (126 bits)
ASRAC_PYRHO / O58478 Alanine/serine racemase; ASR; Ala/Ser racemase; EC 5.1.1.-; EC 5.1.1.1 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
28% identity, 79% coverage of query (126 bits)
4ppmA / A0A0J9X1Q5 Crystal structure of pige: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (map) from serratia sp. Fs14 (see paper)
28% identity, 76% coverage of query (124 bits)
4addA Structural and functional study of succinyl-ornithine transaminase from e. Coli
27% identity, 80% coverage of query (124 bits)
pigE / A0A0J9X1Q5 (S)-3-acetyloctanal aminotransferase monomer from Serratia sp. (strain FS14) (see 4 papers)
PIGE_SERSF / A0A0J9X1Q5 Aminotransferase PigE; EC 2.6.1.- from Serratia sp. (strain FS14) (see paper)
28% identity, 76% coverage of query (124 bits)
4adbB / P77581 Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
27% identity, 80% coverage of query (124 bits)
7lonA Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 76% coverage of query (115 bits)
7lomC Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 76% coverage of query (115 bits)
7lomA Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
27% identity, 76% coverage of query (115 bits)
OAT / P04181 Ornithine aminotransferase (EC 2.6.1.13) from Homo sapiens (see 3 papers)
OAT_HUMAN / P04181 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Homo sapiens (Human) (see 8 papers)
27% identity, 76% coverage of query (114 bits)
7ta0A Human ornithine aminotransferase (hoat) soaked with 5-aminovaleric acid
27% identity, 76% coverage of query (114 bits)
8ez1B Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
27% identity, 76% coverage of query (114 bits)
8ez1A Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
27% identity, 76% coverage of query (114 bits)
7tfpC Human ornithine aminotransferase cocrystallized with its inhibitor, (1s,3s)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.
27% identity, 76% coverage of query (114 bits)
7lk0A Ornithine aminotransferase (oat) cocrystallized with its potent inhibitor - (s)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148)
27% identity, 76% coverage of query (114 bits)
7jx9A The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1s,3s)-3-amino-4- (hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid.
27% identity, 76% coverage of query (114 bits)
6v8dA Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
27% identity, 76% coverage of query (114 bits)
2canA Human ornithine aminotransferase complexed with l-canaline
27% identity, 76% coverage of query (114 bits)
1gbnB Human ornithine aminotransferase complexed with the neurotoxin gabaculine
27% identity, 76% coverage of query (114 bits)
1gbnA Human ornithine aminotransferase complexed with the neurotoxin gabaculine
27% identity, 76% coverage of query (114 bits)
8v9mA Human ornithine aminotransferase cocrystallized with its inhibitor, (r)-3-amino-5,5-difluorocyclohex-1-ene-1-carboxylic acid.
27% identity, 76% coverage of query (114 bits)
7tedA Human ornithine aminotransferase cocrystallized with its inhibitor, (s,e)-3-amino-4-(fluoromethylene)cyclopent-1-ene-1-carboxylate
27% identity, 76% coverage of query (114 bits)
7ta1A Human ornithine aminotransferase (hoat) soaked with gamma-aminobutyric acid
27% identity, 76% coverage of query (114 bits)
7lnmB Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid
27% identity, 76% coverage of query (114 bits)
7lk1A Ornithine aminotransferase (oat) with its potent inhibitor - (s)-3- amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148) - 1 hour soaking
27% identity, 76% coverage of query (114 bits)
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