Searching for up to 100 curated homologs for WP_011880805.1 NCBI__GCF_000016205.1:WP_011880805.1 (318 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YehX / b2129 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yehX / P33360 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli (strain K12) (see 3 papers)
YEHX_ECOLI / P33360 Glycine betaine uptake system ATP-binding protein YehX; EC 7.4.2.- from Escherichia coli (strain K12) (see 2 papers)
51% identity, 92% coverage of query (285 bits)
TC 3.A.1.12.11 / Q8Q041 Glycine betaine transporter, ATP-binding protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
51% identity, 74% coverage of query (254 bits)
OPUCA_BACSU / O34992 Glycine betaine/carnitine/choline transport ATP-binding protein OpuCA from Bacillus subtilis (strain 168) (see 4 papers)
TC 3.A.1.12.4 / O34992 OPCA aka OpuCA, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
46% identity, 91% coverage of query (254 bits)
OSMV_SALTY / Q8ZPK4 Osmoprotectant import ATP-binding protein OsmV; EC 7.6.2.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK4 ABC-type proline/glycine betaine transport system, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
52% identity, 78% coverage of query (252 bits)
OPUBA_BACSU / Q45460 Choline transport ATP-binding protein OpuBA from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / Q45460 OPBA aka OpuBA aka PROV, component of Choline porter from Bacillus subtilis (see 3 papers)
45% identity, 91% coverage of query (250 bits)
OPUCA_LISM4 / G2JZ44 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCA_LISMN / Q9KHT9 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes (see paper)
44% identity, 91% coverage of query (244 bits)
Q87WH5 ABC-type quaternary amine transporter (EC 7.6.2.9) from Pseudomonas syringae (see paper)
TC 3.A.1.12.10 / Q87WH5 OpuCA aka PSPTO4575, component of The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)) from Pseudomonas syringae pv. tomato (see paper)
49% identity, 84% coverage of query (243 bits)
TC 3.A.1.12.8 / Q93A35 BilEA aka OpuBA protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see 2 papers)
47% identity, 75% coverage of query (227 bits)
PS417_27115 putrescine ABC transporter, ATPase component from Pseudomonas simiae WCS417
46% identity, 75% coverage of query (212 bits)
EGTUA_STRP2 / A0A0H2ZLL3 Probable ergothioneine transport ATP-binding protein EgtUA; EC 7.6.2.9 from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
45% identity, 75% coverage of query (208 bits)
TC 3.A.1.12.9 / Q8U4S5 OtaA, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
45% identity, 76% coverage of query (204 bits)
PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
45% identity, 75% coverage of query (204 bits)
TC 3.A.1.12.5 / Q9RQ06 BusAA, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis (see paper)
40% identity, 87% coverage of query (202 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
40% identity, 87% coverage of query (198 bits)
7ahhC Opua inhibited inward-facing, sbd docked
40% identity, 87% coverage of query (198 bits)
GBUA_LISM4 / Q9RR46 Glycine betaine/carnitine transport ATP-binding protein GbuA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
42% identity, 74% coverage of query (194 bits)
ProU / b2677 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
proV / P14175 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli (strain K12) (see 6 papers)
PROV_ECOLI / P14175 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.12.1 / P14175 ProV aka B2677, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 6 papers)
proV / GB|AAC75724.1 glycine betaine/l-proline transport atp-binding protein prov from Escherichia coli K12 (see 6 papers)
44% identity, 74% coverage of query (192 bits)
PROV_SALTY / P17328 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
44% identity, 74% coverage of query (192 bits)
7ahdC Opua (e190q) occluded
43% identity, 71% coverage of query (192 bits)
OUSV_DICD3 / E0SCY1 Glycine betaine/choline transport system ATP-binding protein OusV from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
44% identity, 74% coverage of query (191 bits)
OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168) (see 2 papers)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 4 papers)
40% identity, 85% coverage of query (188 bits)
TC 3.A.1.12.12 / Q9HTI8 Probable ATP-binding component of ABC transporter, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa (see paper)
46% identity, 76% coverage of query (188 bits)
AO353_07790 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2E3
45% identity, 76% coverage of query (187 bits)
TC 3.A.1.6.3 / P0A4W2 Sulfate/thiosulfate import ATP-binding protein CysA aka RV2397C aka MT2468 aka MTCY253.24, component of Sulfate porter from Mycobacterium tuberculosis (see 3 papers)
45% identity, 73% coverage of query (187 bits)
A0A077T7Z1 ABC-type quaternary amine transporter (subunit 1/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
40% identity, 86% coverage of query (187 bits)
AO356_09610 ABC transporter for L-Histidine, ATPase component from Pseudomonas fluorescens FW300-N2C3
45% identity, 71% coverage of query (186 bits)
TC 3.A.1.12.6 / Q9KKE1 HutV aka HISV aka R02702 aka SMC00670, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
44% identity, 71% coverage of query (184 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
42% identity, 79% coverage of query (182 bits)
AO356_13805 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2C3
44% identity, 76% coverage of query (182 bits)
Pf6N2E2_4681 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2E2
44% identity, 76% coverage of query (182 bits)
YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
41% identity, 72% coverage of query (181 bits)
TMOW_PELUB / Q4FL37 Trimethylamine N-oxide transport system ATP-binding protein TmoW; TMAO transport system ATP-binding protein TmoW; EC 7.6.2.9 from Pelagibacter ubique (strain HTCC1062) (see paper)
42% identity, 72% coverage of query (181 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
41% identity, 81% coverage of query (179 bits)
1g291 / Q9YGA6 Malk (see paper)
45% identity, 71% coverage of query (176 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
37% identity, 96% coverage of query (170 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
40% identity, 75% coverage of query (167 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
40% identity, 75% coverage of query (167 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
40% identity, 75% coverage of query (167 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
40% identity, 75% coverage of query (167 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
40% identity, 75% coverage of query (167 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
40% identity, 75% coverage of query (167 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
40% identity, 75% coverage of query (166 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
38% identity, 75% coverage of query (161 bits)
8hprC Lpqy-sugabc in state 4
40% identity, 71% coverage of query (153 bits)
8hprD Lpqy-sugabc in state 4
40% identity, 71% coverage of query (153 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
37% identity, 74% coverage of query (152 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
41% identity, 71% coverage of query (151 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
35% identity, 74% coverage of query (150 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
36% identity, 71% coverage of query (150 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
36% identity, 71% coverage of query (150 bits)
2olkA Abc protein artp in complex with adp-beta-s
36% identity, 71% coverage of query (150 bits)
2oljA Abc protein artp in complex with adp/mg2+
36% identity, 71% coverage of query (150 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
35% identity, 74% coverage of query (149 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
35% identity, 74% coverage of query (149 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
35% identity, 74% coverage of query (149 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
43% identity, 71% coverage of query (149 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
38% identity, 71% coverage of query (148 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
35% identity, 75% coverage of query (147 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
35% identity, 75% coverage of query (147 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
35% identity, 75% coverage of query (147 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
37% identity, 70% coverage of query (145 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
37% identity, 72% coverage of query (142 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
36% identity, 75% coverage of query (135 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
36% identity, 75% coverage of query (135 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
36% identity, 75% coverage of query (135 bits)
8j5qD / P9WQJ5 Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
38% identity, 74% coverage of query (134 bits)
8j5tD Cryo-em structure of mycobacterium tuberculosis oppabcd in the catalytic intermediate state
37% identity, 74% coverage of query (132 bits)
8j5sD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- catalytic intermediate state
37% identity, 74% coverage of query (132 bits)
8wm7D / Q8YZ75 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with signalling protein pii (see paper)
36% identity, 73% coverage of query (127 bits)
8w9mD Cryo-em structure of the cyanobacterial nitrate transporter nrtbcd in complex with atp
35% identity, 73% coverage of query (126 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
35% identity, 75% coverage of query (126 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
33% identity, 70% coverage of query (124 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
30% identity, 88% coverage of query (114 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
37% identity, 70% coverage of query (112 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
35% identity, 75% coverage of query (112 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
35% identity, 73% coverage of query (112 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
36% identity, 70% coverage of query (110 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
34% identity, 71% coverage of query (110 bits)
2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
31% identity, 75% coverage of query (109 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
32% identity, 71% coverage of query (107 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
31% identity, 75% coverage of query (107 bits)
7lkpA Structure of atp-free human abca4
31% identity, 71% coverage of query (106 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
30% identity, 72% coverage of query (103 bits)
7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
32% identity, 76% coverage of query (101 bits)
6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
32% identity, 76% coverage of query (101 bits)
7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
32% identity, 76% coverage of query (100 bits)
Build an alignment for WP_011880805.1 and 86 homologs with ≥ 30% identity
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7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
29% identity, 70% coverage of query (100 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
30% identity, 72% coverage of query (100 bits)
4s0fA Crystal structure of the peptidase-containing abc transporter pcat1 e648q mutant complexed with atpgs in an occluded conformation
28% identity, 70% coverage of query (98.6 bits)
8ee6A / Q8IZY2 Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
33% identity, 78% coverage of query (97.8 bits)
7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
32% identity, 75% coverage of query (97.8 bits)
6quzA Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35
31% identity, 73% coverage of query (97.4 bits)
6qv0A Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
31% identity, 73% coverage of query (97.4 bits)
4q4aA / Q9WYC3 Improved model of amp-pnp bound tm287/288 (see paper)
31% identity, 73% coverage of query (97.1 bits)
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
31% identity, 75% coverage of query (97.1 bits)
7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
31% identity, 75% coverage of query (97.1 bits)
IRTA_MYCS2 / A0R6H8 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
33% identity, 75% coverage of query (96.7 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
32% identity, 74% coverage of query (96.7 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
29% identity, 72% coverage of query (95.9 bits)
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
31% identity, 75% coverage of query (95.5 bits)
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Lawrence Berkeley National Laboratory