Searching for up to 100 curated homologs for WP_011885194.1 NCBI__GCF_000016205.1:WP_011885194.1 (417 a.a.)
Found high-coverage hits (≥70%) to 46 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
O69077 aspartate kinase (EC 2.7.2.4) from Pseudomonas aeruginosa (see paper)
65% identity, 100% coverage of query (539 bits)
AK_PSEFS / C3JXY0 Aspartate kinase; Aspartokinase; EC 2.7.2.4 from Pseudomonas fluorescens (strain SBW25) (see 2 papers)
65% identity, 100% coverage of query (537 bits)
AK_PSEPK / Q88EI9 Aspartate kinase; Aspartokinase; EC 2.7.2.4 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
64% identity, 100% coverage of query (535 bits)
AKLYS_STUS1 / A4VJB4 Aspartate kinase Ask_LysC; Aspartokinase; EC 2.7.2.4 from Stutzerimonas stutzeri (strain A1501) (Pseudomonas stutzeri) (see paper)
64% identity, 100% coverage of query (532 bits)
5yeiC / O69077 Mechanistic insight into the regulation of pseudomonas aeruginosa aspartate kinase (see paper)
64% identity, 99% coverage of query (525 bits)
lysCα / P08495 aspartate kinase II α subunit (EC 2.7.2.4) from Bacillus subtilis (strain 168) (see 4 papers)
lysCβ / P08495 aspartate kinase II β subunit (EC 2.7.2.4) from Bacillus subtilis (strain 168) (see 4 papers)
AK2_BACSU / P08495 Aspartokinase 2; Aspartate kinase 2; Aspartokinase II; EC 2.7.2.4 from Bacillus subtilis (strain 168) (see 2 papers)
P08495 aspartate kinase (EC 2.7.2.4) from Bacillus subtilis (see paper)
lysC / GB|CAA99580.1 aspartate kinase 2; EC 2.7.2.4 from Bacillus subtilis (see paper)
49% identity, 100% coverage of query (348 bits)
AK_CORFL / P41398 Aspartokinase; Aspartate kinase; EC 2.7.2.4 from Corynebacterium flavescens (see paper)
lysC / GB|AAA23293.1 aspartate kinase; EC 2.7.2.4 from Corynebacterium flavescens (see paper)
48% identity, 99% coverage of query (342 bits)
lysCα / P26512 aspartokinase α subunit (EC 2.7.2.4) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
lysCβ / P26512 aspartokinase β subunit (EC 2.7.2.4) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
AK_CORGL / P26512 Aspartokinase; Aspartate kinase; EC 2.7.2.4 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see 2 papers)
P26512 aspartate kinase (EC 2.7.2.4) from Corynebacterium glutamicum (see 2 papers)
lysC aspartate kinase 2; EC 2.7.2.4 from Corynebacterium glutamicum (see 3 papers)
48% identity, 99% coverage of query (342 bits)
AK_THETH / P61489 Aspartokinase; Aspartate kinase; AK; ASK; Threonine-sensitive AK; ThrA; EC 2.7.2.4 from Thermus thermophilus (see 4 papers)
P61489 aspartate kinase (EC 2.7.2.4) from Thermus thermophilus (see 3 papers)
46% identity, 100% coverage of query (336 bits)
AK_THET2 / P61488 Aspartokinase; Aspartate kinase; ASK; EC 2.7.2.4 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
46% identity, 100% coverage of query (335 bits)
AK_MYCTU / P9WPX3 Aspartokinase; Aspartate kinase; ASK; EC 2.7.2.4 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WPX3 aspartate kinase (EC 2.7.2.4) from Mycobacterium tuberculosis (see paper)
45% identity, 99% coverage of query (333 bits)
3aawC / P26512 Crystal structure of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine (see paper)
47% identity, 99% coverage of query (328 bits)
P74569 aspartate kinase (EC 2.7.2.4) from Synechocystis sp. (see paper)
45% identity, 100% coverage of query (317 bits)
3l76A / P74569 Crystal structure of aspartate kinase from synechocystis (see paper)
44% identity, 100% coverage of query (301 bits)
3ab4A / P26512 Crystal structure of feedback inhibition resistant mutant of aspartate kinase from corynebacterium glutamicum in complex with lysine and threonine (see paper)
44% identity, 99% coverage of query (301 bits)
Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
41% identity, 100% coverage of query (299 bits)
2hmfA Structure of a threonine sensitive aspartokinase from methanococcus jannaschii complexed with mg-adp and aspartate
36% identity, 84% coverage of query (193 bits)
3c1mC / Q57991 Cyrstal structure of threonine-sensitive aspartokinase from methanococcus jannaschii with mgamp-pnp and l-aspartate (see paper)
36% identity, 84% coverage of query (191 bits)
Q57991 aspartate kinase (EC 2.7.2.4) from Methanocaldococcus jannaschii (see 2 papers)
36% identity, 84% coverage of query (190 bits)
3c1nA Crystal structure of allosteric inhibition threonine-sensitive aspartokinase from methanococcus jannaschii with l-threonine
36% identity, 84% coverage of query (189 bits)
dapG / Q04795 aspartokinase I (alpha and beta subunits) (EC 2.7.2.4) from Bacillus subtilis (strain 168) (see 6 papers)
35% identity, 100% coverage of query (180 bits)
dapG aspartate kinase 1; EC 2.7.2.4 from Bacillus subtilis (see paper)
35% identity, 100% coverage of query (180 bits)
Q9RUL9 aspartate kinase (EC 2.7.2.4) from Deinococcus radiodurans (see paper)
31% identity, 99% coverage of query (165 bits)
CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Pedobacter sp. GW460-11-11-14-LB5
30% identity, 98% coverage of query (144 bits)
Build an alignment for WP_011885194.1 and 24 homologs with ≥ 30% identity
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Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Echinicola vietnamensis KMM 6221, DSM 17526
28% identity, 87% coverage of query (134 bits)
AK2_ARATH / O23653 Aspartokinase 2, chloroplastic; Aspartate kinase 2; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O23653 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
29% identity, 98% coverage of query (132 bits)
2cdqA / Q9LYU8 Crystal structure of arabidopsis thaliana aspartate kinase complexed with lysine and s- adenosylmethionine (see paper)
28% identity, 98% coverage of query (132 bits)
AK1_ARATH / Q9LYU8 Aspartokinase 1, chloroplastic; Aspartate kinase 1; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LYU8 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
28% identity, 98% coverage of query (132 bits)
thrA1A2 / CAA43212.1 aspartate kinase from Serratia marcescens (see paper)
32% identity, 70% coverage of query (131 bits)
AK3 / Q9S702 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see paper)
AK3_ARATH / Q9S702 Aspartokinase 3, chloroplastic; Aspartate kinase 3; EC 2.7.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9S702 aspartate kinase (EC 2.7.2.4) from Arabidopsis thaliana (see 2 papers)
28% identity, 98% coverage of query (130 bits)
ThrD / b0002 fused aspartate kinase/homoserine dehydrogenase 1 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli K-12 substr. MG1655 (see paper)
thrA / P00561 fused aspartate kinase/homoserine dehydrogenase 1 (EC 2.7.2.4; EC 1.1.1.3) from Escherichia coli (strain K12) (see 33 papers)
P00561 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Escherichia coli (see paper)
30% identity, 82% coverage of query (129 bits)
Q5JK18 aspartate kinase (EC 2.7.2.4) from Oryza sativa Japonica Group (see paper)
26% identity, 98% coverage of query (124 bits)
AKH2_ARATH / O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
30% identity, 84% coverage of query (122 bits)
AKH1_ARATH / Q9SA18 Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic; AK-HD 1; AK-HSDH 1; Beta-aspartyl phosphate homoserine 1; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
26% identity, 99% coverage of query (122 bits)
O63067 homoserine dehydrogenase (EC 1.1.1.3) from Glycine max (see paper)
29% identity, 84% coverage of query (119 bits)
AK_YEAST / P10869 Aspartokinase; Aspartate kinase; EC 2.7.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P10869 aspartate kinase (EC 2.7.2.4) from Saccharomyces cerevisiae (see paper)
27% identity, 87% coverage of query (117 bits)
BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) from Bacteroides thetaiotaomicron VPI-5482
29% identity, 85% coverage of query (111 bits)
Q97MC0 aspartate kinase (EC 2.7.2.4) from Clostridium acetobutylicum (see paper)
25% identity, 71% coverage of query (111 bits)
3tviE / Q97MC0 Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production (see paper)
25% identity, 71% coverage of query (111 bits)
O60163 Probable aspartokinase; Aspartate kinase; EC 2.7.2.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
26% identity, 85% coverage of query (108 bits)
2j0wA / P08660 Crystal structure of e. Coli aspartokinase iii in complex with aspartate and adp (r-state) (see paper)
30% identity, 88% coverage of query (105 bits)
Apk / b4024 aspartate kinase III (EC 2.7.2.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lysC / P08660 aspartate kinase III (EC 2.7.2.4) from Escherichia coli (strain K12) (see 27 papers)
AK3_ECOLI / P08660 Lysine-sensitive aspartokinase 3; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase III; EC 2.7.2.4 from Escherichia coli (strain K12) (see 2 papers)
P08660 aspartate kinase (EC 2.7.2.4) from Escherichia coli (see paper)
30% identity, 88% coverage of query (105 bits)
2j0xA Crystal structure of e. Coli aspartokinase iii in complex with lysine and aspartate (t-state)
30% identity, 88% coverage of query (105 bits)
3tviA Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production
24% identity, 83% coverage of query (103 bits)
ABZR86_RS19560 aspartate kinase / diaminopimelate decarboxylase (EC 4.1.1.20; EC 2.7.2.4) from Dyella japonica UNC79MFTsu3.2
25% identity, 98% coverage of query (94.7 bits)
FUB3_GIBF5 / S0DVT6 Aspartate kinase FUB3; Fusaric acid biosynthesis protein 3; EC 2.7.2.4 from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 9 papers)
27% identity, 82% coverage of query (90.5 bits)
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Lawrence Berkeley National Laboratory