Searching for up to 100 curated homologs for WP_011912234.1 NCBI__GCF_000013785.1:WP_011912234.1 (435 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8G2R2 histidinol dehydrogenase (EC 1.1.1.23) from Brucella suis bv. 1 (see paper)
    50% identity, 98% coverage of query (407 bits)

4g09A / Q8G2R2 The crystal structure of the c366s mutant of hdh from brucella suis in complex with a substituted benzyl ketone (see paper)
    50% identity, 98% coverage of query (405 bits)

HisD / b2020 histidinal/histidinol dehydrogenase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hisD / P06988 histidinal/histidinol dehydrogenase (EC 1.1.1.23) from Escherichia coli (strain K12) (see 5 papers)
HISX_ECOLI / P06988 Histidinol dehydrogenase; HDH; EC 1.1.1.23 from Escherichia coli (strain K12) (see paper)
1kaeA / P06988 L-histidinol dehydrogenase (hisd) structure complexed with l- histidinol (substrate), zinc and NAD (cofactor) (see paper)
    39% identity, 98% coverage of query (293 bits)

1karA L-histidinol dehydrogenase (hisd) structure complexed with histamine (inhibitor), zinc and NAD (cofactor)
    39% identity, 98% coverage of query (293 bits)

1kahA L-histidinol dehydrogenase (hisd) structure complexed with l-histidine (product), zn and NAD (cofactor)
    39% identity, 98% coverage of query (293 bits)

HISX_SALTY / P10370 Histidinol dehydrogenase; HDH; EC 1.1.1.23 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    38% identity, 95% coverage of query (289 bits)

A1BPP9 histidinol dehydrogenase (EC 1.1.1.23) from Geotrichum candidum (see paper)
    38% identity, 92% coverage of query (267 bits)

HIS2_YEAST / P00815 Histidine biosynthesis trifunctional protein; EC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    37% identity, 90% coverage of query (262 bits)

5vlcA Crystal structure of medicago truncatula l-histidinol dehydrogenase in complex with l-histidinol
    37% identity, 95% coverage of query (261 bits)

HISX_MYCTU / P9WNW9 Histidinol dehydrogenase; HDH; EC 1.1.1.23 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WNW9 histidinol dehydrogenase (EC 1.1.1.23) from Mycobacterium tuberculosis (see paper)
    41% identity, 91% coverage of query (259 bits)

5vldF / G7IKX3 Crystal structure of medicago truncatula l-histidinol dehydrogenase in complex with l-histidine and NAD+ (see paper)
    37% identity, 95% coverage of query (259 bits)

G7IKX3 histidinol dehydrogenase (EC 1.1.1.23) from Medicago truncatula (see paper)
    37% identity, 95% coverage of query (259 bits)

5vlbA Crystal structure of medicago truncatula l-histidinol dehydrogenase in complex with imidazole
    37% identity, 95% coverage of query (259 bits)

6an0A / A0A077ECF2 Crystal structure of histidinol dehydrogenase from elizabethkingia anophelis
    33% identity, 91% coverage of query (251 bits)

his2 / RF|NP_595886.1 histidinol dehydrogenase His2 (predicted); EC 1.1.1.23 from Schizosaccharomyces pombe (see 2 papers)
    37% identity, 91% coverage of query (251 bits)

HIS4 multifunctional enzyme that catalyzes three steps of histidine biosynthesis from Candida albicans (see 4 papers)
    36% identity, 91% coverage of query (243 bits)

hpsN / Q46N53 sulfopropanediol 3-dehydrogenase monomer (EC 1.1.1.308) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
HPSN_CUPPJ / Q46N53 Sulfopropanediol 3-dehydrogenase; 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming); DHPS 3-dehydrogenase (sulfolactate forming); EC 1.1.1.308 from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator (strain JMP 134)) (see paper)
Q46N53 sulfopropanediol 3-dehydrogenase (EC 1.1.1.308) from Cupriavidus pinatubonensis (see paper)
    34% identity, 91% coverage of query (232 bits)

his4 / CAC03753.1 histidinol dehydrogenase, partial from Schwanniomyces occidentalis (see 2 papers)
    37% identity, 79% coverage of query (218 bits)

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