Searching for up to 100 curated homologs for WP_011937432.1 NCBI__GCF_000016745.1:WP_011937432.1 (312 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6yakDDD 6yakDDD (see paper)
59% identity, 99% coverage of query (375 bits)
SQWH_CLOS9 / J1H0Z7 6-deoxy-6-sulfo-D-fructose transketolase subunit SqwH; EC 2.2.1.15 from Clostridium sp. (strain MSTE9)
46% identity, 98% coverage of query (263 bits)
APTB_PHOV8 / A6KXB3 Apulose-4-phosphate transketolase subunit B; Apulose-4-phosphate transketolase C-terminal subunit; EC 2.2.1.13 from Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) (Bacteroides vulgatus) (see paper)
A6KXB3 apulose-4-phosphate transketolase (subunit 2/2) (EC 2.2.1.13) from Phocaeicola vulgatus (see paper)
40% identity, 99% coverage of query (232 bits)
A0A0F6B483 transketolase (subunit 1/2) (EC 2.2.1.1) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
40% identity, 91% coverage of query (232 bits)
P40142 transketolase (EC 2.2.1.1) from Mus musculus (see paper)
43% identity, 98% coverage of query (218 bits)
TKT_HUMAN / P29401 Transketolase; TK; EC 2.2.1.1 from Homo sapiens (Human) (see 2 papers)
P29401 transketolase (EC 2.2.1.1) from Homo sapiens (see 5 papers)
41% identity, 98% coverage of query (214 bits)
6rjbB / P29401 Human transketolase variant t382e (see paper)
41% identity, 98% coverage of query (214 bits)
4kxxA Human transketolase in covalent complex with donor ketose d- sedoheptulose-7-phosphate
41% identity, 98% coverage of query (214 bits)
6ha3A Human transketolase variant e160q in covalent complex with donor ketose d-fructose-6-phosphate
41% identity, 98% coverage of query (213 bits)
8waaA Human transketolase soaked with donor ketose d-xylulose
41% identity, 98% coverage of query (213 bits)
8wa9A Human transketolase soaked with donor ketose d-fructose
41% identity, 98% coverage of query (213 bits)
4kxyA Human transketolase in complex with thdp analogue (r)-2-(1,2- dihydroxyethyl)-3-deaza-thdp
41% identity, 98% coverage of query (213 bits)
4kxvA Human transketolase in covalent complex with donor ketose d-xylulose- 5-phosphate, crystal 1
41% identity, 98% coverage of query (213 bits)
4kxuA Human transketolase in covalent complex with donor ketose d-fructose- 6-phosphate
41% identity, 98% coverage of query (213 bits)
TKTL1_HUMAN / P51854 Transketolase-like protein 1; Transketolase 2; TK 2; Transketolase-related protein; EC 2.2.1.1 from Homo sapiens (Human) (see 3 papers)
P51854 transketolase (EC 2.2.1.1) from Homo sapiens (see 4 papers)
39% identity, 98% coverage of query (197 bits)
TKTL2_HUMAN / Q9H0I9 Transketolase-like protein 2; EC 2.2.1.1 from Homo sapiens (Human) (see paper)
Q9H0I9 transketolase (EC 2.2.1.1) from Homo sapiens (see paper)
36% identity, 94% coverage of query (175 bits)
aptB / A6VKQ3 apulose-4-phosphate transketolase subunit B (EC 2.2.1.13) from Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) (see paper)
APTB_ACTSZ / A6VKQ3 Apulose-4-phosphate transketolase subunit B; Apulose-4-phosphate transketolase C-terminal subunit; EC 2.2.1.13 from Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) (see paper)
A6VKQ3 apulose-4-phosphate transketolase (subunit 2/2) (EC 2.2.1.13) from Actinobacillus succinogenes (see paper)
34% identity, 90% coverage of query (174 bits)
TKTL1_MOUSE / Q99MX0 Transketolase-like protein 1; Transketolase 2; TK 2; EC 2.2.1.1 from Mus musculus (Mouse) (see paper)
35% identity, 98% coverage of query (171 bits)
P73067 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Synechocystis sp. (see paper)
34% identity, 92% coverage of query (149 bits)
dxs / P54523 1-deoxyxylulose-5-phosphate synthase (EC 2.2.1.7) from Bacillus subtilis (strain 168) (see 4 papers)
34% identity, 96% coverage of query (146 bits)
Q8L692 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Medicago truncatula (see paper)
31% identity, 98% coverage of query (139 bits)
8a4dA 1-deoxy-d-xylulose 5-phosphate synthase from pseudomonas aeruginosa with a thiamine analog inhibitor
31% identity, 96% coverage of query (139 bits)
2o1sB / P77488 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from escherichia coli (see paper)
31% identity, 95% coverage of query (138 bits)
8a5kA Structural analysis of 1-deoxy-d-xylulose 5-phosphate synthase from pseudomonas aeruginosa and klebsiella pneumoniae reveals conformational changes upon cofactor binding
31% identity, 92% coverage of query (138 bits)
8a45F / B7V7R4 Structural analysis of 1-deoxy-d-xylulose 5-phosphate synthase from pseudomonas aeruginosa with 2-acetyl thiamine diphosphate (see paper)
31% identity, 92% coverage of query (137 bits)
2o1sA / P77488 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from escherichia coli (see paper)
32% identity, 92% coverage of query (137 bits)
YajP / b0420 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dxs / P77488 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (strain K12) (see 26 papers)
DXS_ECOLI / P77488 1-deoxy-D-xylulose-5-phosphate synthase; 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; EC 2.2.1.7 from Escherichia coli (strain K12) (see 3 papers)
32% identity, 92% coverage of query (137 bits)
Q8L693 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Medicago truncatula (see paper)
30% identity, 96% coverage of query (130 bits)
8bzxB / A6T5F3 1-deoxy-d-xylulose 5-phosphate synthase from klebsiella pneumoniae (kpdxps),co-crystal with thiamine monophosphate analog (see paper)
31% identity, 94% coverage of query (129 bits)
A7LA01 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267); 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Picea abies (see 2 papers)
31% identity, 95% coverage of query (129 bits)
8a9cB / A6T5F3 Structure of truncated 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from klebsiella pneumoniae in complex with cofactor tpp
32% identity, 92% coverage of query (129 bits)
Q5J7B4 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Ginkgo biloba (see paper)
33% identity, 85% coverage of query (129 bits)
8bzxA / A6T5F3 1-deoxy-d-xylulose 5-phosphate synthase from klebsiella pneumoniae (kpdxps),co-crystal with thiamine monophosphate analog (see paper)
32% identity, 92% coverage of query (128 bits)
A7LA00 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267); 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Picea abies (see 2 papers)
34% identity, 81% coverage of query (127 bits)
A7LA02 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267); 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Picea abies (see 2 papers)
32% identity, 84% coverage of query (127 bits)
B9U4U0 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Pinus densiflora (see paper)
31% identity, 96% coverage of query (126 bits)
6xxgBBB / Q9RUB5 6xxgBBB (see paper)
30% identity, 90% coverage of query (125 bits)
6ouvA / Q9RUB5 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus radiodurans with methylacetylphosphonate (map) bound (see paper)
30% identity, 90% coverage of query (125 bits)
6xxgAAA / Q9RUB5 6xxgAAA (see paper)
30% identity, 90% coverage of query (125 bits)
DXS_DEIRA / Q9RUB5 1-deoxy-D-xylulose-5-phosphate synthase; 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; EC 2.2.1.7 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
Q9RUB5 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Deinococcus radiodurans (see 2 papers)
30% identity, 90% coverage of query (125 bits)
8v9iA 1-deoxy-D-xylulose-5-phosphate synthase
30% identity, 90% coverage of query (125 bits)
6ouwA 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus radiodurans with enamine intermediate bound
30% identity, 90% coverage of query (125 bits)
I1YA59 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Withania somnifera (see paper)
31% identity, 93% coverage of query (124 bits)
dxs2 / BAB83664.1 1-deoxy-D-xylulose 5-phosphate synthase from Kitasatospora griseola (see paper)
30% identity, 97% coverage of query (124 bits)
D2CS41 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Nicotiana tabacum (see paper)
31% identity, 93% coverage of query (124 bits)
2o1xA 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from deinococcus radiodurans
30% identity, 90% coverage of query (124 bits)
B9U4U6 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Pinus densiflora (see paper)
32% identity, 81% coverage of query (122 bits)
C6G1Y5 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Wurfbainia villosa (see paper)
31% identity, 89% coverage of query (122 bits)
dxs / BAB20589.1 1-deoxy-D-xylulose 5-phosphate synthase from Kitasatospora griseola (see paper)
32% identity, 92% coverage of query (121 bits)
dxs / A7BKB8 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Croton stellatopilosus (see paper)
A7BKB8 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Croton stellatopilosus (see 2 papers)
30% identity, 97% coverage of query (120 bits)
E7CCH1 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Solanum tuberosum (see paper)
30% identity, 93% coverage of query (120 bits)
C7U110 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Solanum lycopersicum (see paper)
30% identity, 93% coverage of query (120 bits)
Build an alignment for WP_011937432.1 and 52 homologs with ≥ 30% identity
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H5ZXI0 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Botryococcus braunii (see paper)
29% identity, 99% coverage of query (118 bits)
Q5J5B3 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Ginkgo biloba (see paper)
33% identity, 81% coverage of query (117 bits)
CLA1 / Q38854 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) from Arabidopsis thaliana (see paper)
DXS_ARATH / Q38854 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic; 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; Protein CLOROPLASTOS ALTERADOS 1; EC 2.2.1.7 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
31% identity, 92% coverage of query (117 bits)
G8EX76 transketolase (EC 2.2.1.1) from Cucumis sativus (see paper)
33% identity, 97% coverage of query (107 bits)
Cpl-tkt3 / CAA86607.1 transketolase, partial from Craterostigma plantagineum (see paper)
31% identity, 97% coverage of query (106 bits)
TKTC2_ARATH / F4IW47 Transketolase-2, chloroplastic; TK; EC 2.2.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
32% identity, 97% coverage of query (105 bits)
F4JBY2 transketolase (EC 2.2.1.1) from Arabidopsis thaliana (see paper)
32% identity, 97% coverage of query (105 bits)
TKTC1_ARATH / Q8RWV0 Transketolase-1, chloroplastic; TK; EC 2.2.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
32% identity, 97% coverage of query (105 bits)
7a9gAAA / P9WNS3 7a9gAAA (see paper)
28% identity, 96% coverage of query (102 bits)
7a9gBBB 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase
28% identity, 96% coverage of query (102 bits)
7a9hAAA 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase
28% identity, 96% coverage of query (102 bits)
8oghA Truncated 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from mycobacterium tuberculosis with butylacetylphosphonate (bap) bound
28% identity, 96% coverage of query (102 bits)
bfmBAB / P37941 2-keto-isovalerate dehydrogenase component β subunit (EC 1.2.4.4) from Bacillus subtilis (strain 168) (see 2 papers)
30% identity, 87% coverage of query (100 bits)
TKT_NOSS1 / Q8YRU9 Transketolase; TK; EC 2.2.1.1 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
31% identity, 98% coverage of query (99.0 bits)
Q5QKF8 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Agrobacterium tumefaciens (see paper)
33% identity, 81% coverage of query (97.8 bits)
TKT1_YEAST / P23254 Transketolase 1; TK 1; EC 2.2.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P23254 transketolase (EC 2.2.1.1) from Saccharomyces cerevisiae (see 6 papers)
32% identity, 84% coverage of query (97.4 bits)
1ay0A / P23254 Identification of catalytically important residues in yeast transketolase (see paper)
32% identity, 84% coverage of query (97.4 bits)
Q0GGQ3 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Agrobacterium tumefaciens (see paper)
32% identity, 81% coverage of query (97.4 bits)
1tkcA Specificity of coenzyme binding in thiamin diphosphate dependent enzymes: crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate
32% identity, 84% coverage of query (97.4 bits)
1tkbA Specificity of coenzyme binding in thiamin diphosphate dependent enzymes: crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate
32% identity, 84% coverage of query (97.4 bits)
1tkaA Specificity of coenzyme binding in thiamin diphosphate dependent enzymes: crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate
32% identity, 84% coverage of query (97.4 bits)
1ngsA Complex of transketolase with thiamin diphosphate, ca2+ and acceptor substrate erythrose-4-phosphate
32% identity, 84% coverage of query (97.4 bits)
1gpuA Transketolase complex with reaction intermediate
32% identity, 84% coverage of query (97.4 bits)
5nd5A / A8IAN1 Crystal structure of transketolase from chlamydomonas reinhardtii in complex with tpp and mg2+ (see paper)
31% identity, 98% coverage of query (95.1 bits)
8ci0CCC Transketolase, chloroplastic
30% identity, 97% coverage of query (93.6 bits)
8ci0AAA / Q7SIC9 8ci0AAA (see paper)
30% identity, 97% coverage of query (93.6 bits)
TKTC_MAIZE / Q7SIC9 Transketolase, chloroplastic; TK; EC 2.2.1.1 from Zea mays (Maize) (see paper)
30% identity, 97% coverage of query (93.6 bits)
3m49A / A0A6L7H165 Crystal structure of transketolase complexed with thiamine diphosphate from bacillus anthracis
29% identity, 97% coverage of query (92.8 bits)
3uptA / Q2SZA7 Crystal structure of a transketolase from burkholderia pseudomallei bound to tpp, calcium and ribose-5-phosphate (see paper)
30% identity, 98% coverage of query (90.9 bits)
8wa7A E.Coli transketolase soaked with donor ketose d-fructose
31% identity, 84% coverage of query (90.1 bits)
TktA / b2935 transketolase 1 (EC 2.2.1.1) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
tktA / P27302 transketolase 1 (EC 2.2.1.1) from Escherichia coli (strain K12) (see 64 papers)
TKT1_ECOLI / P27302 Transketolase 1; TK 1; EC 2.2.1.1 from Escherichia coli (strain K12) (see 2 papers)
P27302 transketolase (EC 2.2.1.1) from Escherichia coli (see 5 papers)
31% identity, 84% coverage of query (90.1 bits)
2r8pA Transketolase from e. Coli in complex with substrate d-fructose-6- phosphate
31% identity, 84% coverage of query (90.1 bits)
2r8oA Transketolase from e. Coli in complex with substrate d-xylulose-5- phosphate
31% identity, 84% coverage of query (90.1 bits)
6tj9A Escherichia coli transketolase in complex with cofactor analog 2'- methoxythiamine and substrate xylulose 5-phosphate
31% identity, 84% coverage of query (90.1 bits)
6tj8A Escherichia coli transketolase in complex with cofactor analog 2'- methoxythiamine diphosphate
31% identity, 84% coverage of query (90.1 bits)
1qgdA Transketolase from escherichia coli
31% identity, 84% coverage of query (89.7 bits)
2r5nA Crystal structure of transketolase from escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate
31% identity, 84% coverage of query (89.7 bits)
8r3oB / P43757 Transketolase from haemophilus influenzae in complex with thiamin pyrophosphate
29% identity, 96% coverage of query (89.7 bits)
3m7iA Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate(pyranose form) and magnesium ion
30% identity, 96% coverage of query (89.4 bits)
3m6lA Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate and calcium ion
30% identity, 96% coverage of query (89.4 bits)
3m34A / Q0P7Y3 Crystal structure of transketolase in complex with thiamin diphosphate and calcium ion
30% identity, 96% coverage of query (89.4 bits)
TktB / b2465 transketolase 2 (EC 2.2.1.1) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
tktB / P33570 transketolase 2 (EC 2.2.1.1) from Escherichia coli (strain K12) (see 18 papers)
TKT2_ECOLI / P33570 Transketolase 2; TK 2; EC 2.2.1.1 from Escherichia coli (strain K12) (see paper)
P33570 transketolase (EC 2.2.1.1) from Escherichia coli (see paper)
29% identity, 99% coverage of query (86.7 bits)
5vrbA / B4RKU9 Crystal structure of a transketolase from neisseria gonorrhoeae
30% identity, 98% coverage of query (86.7 bits)
8qmfA / Q7MDD4 Transketolase from vibrio vulnificus in complex with thiamin pyrophosphate (see paper)
28% identity, 99% coverage of query (86.3 bits)
8cipA / A0A0I9QGZ2 Crystal structure of transketolase from geobacillus stearothermophilus
28% identity, 98% coverage of query (85.9 bits)
7wrtA X-ray structure ofthermus thermophilus hb8 transketorase demonstrate in complex with tpp and d-erythrose-4-phosphate
30% identity, 96% coverage of query (85.5 bits)
7wrrA / Q5SM35 X-ray structure of thermus thermophilus hb8 transketorase in complex with tpp and mes (see paper)
30% identity, 96% coverage of query (85.5 bits)
5hhtB / P27302 Crystal structure of e. Coli transketolase triple variant ser385tyr/asp469thr/arg520gln (see paper)
31% identity, 84% coverage of query (84.7 bits)
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Lawrence Berkeley National Laboratory