Searching for up to 100 curated homologs for WP_011970089.1 NCBI__GCF_000017145.1:WP_011970089.1 (334 a.a.)
Found high-coverage hits (≥70%) to 85 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
OTCC_PSEAE / P08308 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 8 papers)
69% identity, 100% coverage of query (513 bits)
4jfrB / Q8DCF5 Crystal structure of anabolic ornithine carbamoyltransferase from vibrio vulnificus in complex with carbamoyl phosphate
59% identity, 100% coverage of query (440 bits)
4jhxA Crystal structure of anabolic ornithine carbamoyltransferase from vibrio vulnificus in complex with carbamoylphosphate and arginine
59% identity, 100% coverage of query (440 bits)
4jqoA Crystal structure of anabolic ornithine carbamoyltransferase from vibrio vulnificus in complex with citrulline and inorganic phosphate
59% identity, 100% coverage of query (439 bits)
Q8DCF5 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Vibrio vulnificus (strain CMCP6)
59% identity, 100% coverage of query (439 bits)
4h31A Crystal structure of anabolic ornithine carbamoyltransferase from vibrio vulnificus in complex with carbamoyl phosphate and l-norvaline
59% identity, 100% coverage of query (439 bits)
ArgF / b0273 CP4-6 prophage; ornithine carbamoyltransferase ArgF (EC 2.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
argF / P06960 CP4-6 prophage; ornithine carbamoyltransferase ArgF (EC 2.1.3.3) from Escherichia coli (strain K12) (see 10 papers)
OTC2_ECOLI / P06960 Ornithine carbamoyltransferase subunit F; OTCase-2; EC 2.1.3.3 from Escherichia coli (strain K12) (see 2 papers)
57% identity, 99% coverage of query (407 bits)
ArgI / b4254 ornithine carbamoyltransferase ArgI (EC 2.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
argI / P04391 ornithine carbamoyltransferase ArgI (EC 2.1.3.3) from Escherichia coli (strain K12) (see 10 papers)
OTC1_ECOLI / P04391 Ornithine carbamoyltransferase subunit I; OTCase-1; EC 2.1.3.3 from Escherichia coli (strain K12) (see 11 papers)
argI / GB|AAA23483.1 ornithine carbamoyltransferase, subunit I; EC 2.1.3.3 from Escherichia coli K12 (see 2 papers)
57% identity, 98% coverage of query (405 bits)
1duvG / P04391 Crystal structure of e. Coli ornithine transcarbamoylase complexed with ndelta-l-ornithine-diaminophosphinyl-n-sulphonic acid (psorn) (see paper)
57% identity, 98% coverage of query (405 bits)
2otcA Ornithine transcarbamoylase complexed with n-(phosphonacetyl)-l- ornithine
57% identity, 98% coverage of query (403 bits)
arcB / E3PX87 ornithine carbamoyltransferase (EC 2.1.3.3) from Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / CCUG 9281 / NCIMB 10654 / HF) (see paper)
52% identity, 100% coverage of query (362 bits)
OTCC_LENHI / Q8G998 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Lentilactobacillus hilgardii (Lactobacillus hilgardii) (see paper)
arcB / CAD13392.1 ornithine transcarbamylase from Lactobacillus hilgardii (see paper)
50% identity, 99% coverage of query (343 bits)
arcB / CAC41342.1 ornithine transcarbamylase from Enterococcus faecalis (see 2 papers)
50% identity, 100% coverage of query (342 bits)
arcB / CAA04683.1 ornithine transcarbamoylase from Lactobacillus sakei (see 2 papers)
48% identity, 99% coverage of query (329 bits)
OTCC_MALP2 / Q8EVF5 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Malacoplasma penetrans (strain HF-2) (Mycoplasma penetrans) (see paper)
47% identity, 100% coverage of query (317 bits)
arcB / P75473 ornithine carbamoyltransferase, catabolic (EC 2.1.3.3) from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (see paper)
43% identity, 100% coverage of query (288 bits)
OTC2A_PSESH / P68747 Ornithine carbamoyltransferase 2, anabolic; OTCase 2; Ornithine carbamoyltransferase 2, phaseolotoxin-insensitive; Phaseolotoxin-resistant ornithine carbamoyltransferase; Toxin-resistant enzyme; ROCT; EC 2.1.3.3 from Pseudomonas savastanoi pv. phaseolicola (Pseudomonas syringae pv. phaseolicola) (see 5 papers)
P68747 ornithine carbamoyltransferase (EC 2.1.3.3) from Pseudomonas savastanoi pv. phaseolicola (see paper)
argK / BAF32851.1 OTCase from Pseudomonas syringae pv. actinidiae (see 4 papers)
argK / BAF32902.1 OTCase from Pseudomonas savastanoi pv. phaseolicola (see 4 papers)
42% identity, 99% coverage of query (263 bits)
O93656 ornithine carbamoyltransferase (EC 2.1.3.3) from Pyrococcus abyssi (see paper)
41% identity, 100% coverage of query (232 bits)
OTCA_PYRFU / Q51742 Ornithine carbamoyltransferase, anabolic; OTCase; EC 2.1.3.3 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 2 papers)
Q51742 ornithine carbamoyltransferase (EC 2.1.3.3) from Pyrococcus furiosus (see 2 papers)
40% identity, 100% coverage of query (226 bits)
argF / P18186 ArgF (EC 2.1.3.3) from Bacillus subtilis (strain 168) (see 2 papers)
39% identity, 99% coverage of query (218 bits)
OTC_MYCS2 / A0QYS8 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
36% identity, 97% coverage of query (213 bits)
Q81M99 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Bacillus anthracis
39% identity, 98% coverage of query (213 bits)
4nf2A / Q81M99 Crystal structure of anabolic ornithine carbamoyltransferase from bacillus anthracis in complex with carbamoyl phosphate and l- norvaline
39% identity, 98% coverage of query (209 bits)
PTC_ENTFA / Q837U7 Putrescine carbamoyltransferase; PTC; PTCase; Agmatine catabolism protein B; Putrescine transcarbamoylase; Putrescine transcarbamylase; EC 2.1.3.6 from Enterococcus faecalis (strain ATCC 700802 / V583) (see 4 papers)
Q837U7 ornithine carbamoyltransferase (EC 2.1.3.3); putrescine carbamoyltransferase (EC 2.1.3.6) from Enterococcus faecalis (see 2 papers)
37% identity, 98% coverage of query (206 bits)
4a8hA Crystal structure of putrescine transcarbamylase from enterococcus faecalis with n-(phosphonoacetyl)-putrescine
37% identity, 98% coverage of query (206 bits)
4am8D / Q837U7 Crystal structure of the r54g mutant of putrescine transcarbamylase from enterococcus faecalis bound to a curing guanidinium ion
37% identity, 98% coverage of query (203 bits)
4am8A Crystal structure of the r54g mutant of putrescine transcarbamylase from enterococcus faecalis bound to a curing guanidinium ion
37% identity, 98% coverage of query (203 bits)
OTC_CHICK / Q9YHY9 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Gallus gallus (Chicken) (see 4 papers)
35% identity, 100% coverage of query (199 bits)
OTC / P00480 Ornithine carbamoyltransferase, mitochondrial (EC 2.1.3.3) from Homo sapiens (see 8 papers)
OTC_HUMAN / P00480 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Homo sapiens (Human) (see 35 papers)
P00480 ornithine carbamoyltransferase (EC 2.1.3.3) from Homo sapiens (see 3 papers)
35% identity, 99% coverage of query (199 bits)
1c9yA / P00480 Human ornithine transcarbamylase: crystallographic insights into substrate recognition and catalytic mechanism (see paper)
35% identity, 99% coverage of query (198 bits)
1othA Crystal structure of human ornithine transcarbamoylase complexed with n-phosphonacetyl-l-ornithine
35% identity, 99% coverage of query (198 bits)
OTC_MOUSE / P11725 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Mus musculus (Mouse) (see paper)
35% identity, 99% coverage of query (196 bits)
OTC_SHEEP / P84010 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Ovis aries (Sheep) (see paper)
35% identity, 99% coverage of query (196 bits)
OTC_RAT / P00481 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Rattus norvegicus (Rat) (see paper)
35% identity, 99% coverage of query (195 bits)
OTCA_PSEAE / P11724 Ornithine carbamoyltransferase, anabolic; OTCase; EC 2.1.3.3 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
36% identity, 96% coverage of query (195 bits)
PTC_STRMU / Q8DW19 Putrescine carbamoyltransferase; PTC; PTCase; Putrescine transcarbamoylase; Putrescine transcarbamylase; EC 2.1.3.6 from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see paper)
34% identity, 99% coverage of query (195 bits)
OTC_SCHPO / P31317 Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; OTCase; EC 2.1.3.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
arg3 / GI|1204211 ornithine carbamoyltransferase Arg3; EC 2.1.3.3 from Schizosaccharomyces pombe (see 2 papers)
34% identity, 99% coverage of query (194 bits)
Q9PNU6 ornithine carbamoyltransferase (EC 2.1.3.3) from Campylobacter jejuni (see paper)
35% identity, 96% coverage of query (189 bits)
Q5SJ15 ornithine carbamoyltransferase (EC 2.1.3.3) from Thermus thermophilus (see paper)
37% identity, 97% coverage of query (189 bits)
OTC_THET2 / P96134 Ornithine carbamoyltransferase; OTC; OTCase; EC 2.1.3.3 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
37% identity, 97% coverage of query (188 bits)
7nnvA / P9WIT9 Crystal structure of mycobacterium tuberculosis argf in complex with carbamoyl phosphate.
34% identity, 97% coverage of query (187 bits)
7nouA Crystal structure of mycobacterium tuberculosis argf in complex with (3,5-dichlorophenyl)boronic acid.
34% identity, 97% coverage of query (187 bits)
7nosA Crystal structure of mycobacterium tuberculosis argf in complex with 4-bromo-6-(trifluoromethyl)-1h-benzo[d]imidazole.
34% identity, 97% coverage of query (187 bits)
7norA Crystal structure of mycobacterium tuberculosis argf in complex with 2-fluoro-4-hydroxybenzonitrile.
34% identity, 97% coverage of query (187 bits)
7nnyA Crystal structure of mycobacterium tuberculosis argf in complex with naphthalen-1-ol.
34% identity, 97% coverage of query (187 bits)
7nnwA Crystal structure of mycobacterium tuberculosis argf in complex with methyl 4-hydroxy-3-iodobenzoate.
34% identity, 97% coverage of query (187 bits)
2i6uA Crystal structure of ornithine carbamoyltransferase complexed with carbamoyl phosphate and l-norvaline from mycobacterium tuberculosis (rv1656) at 2.2 a
34% identity, 97% coverage of query (187 bits)
OTC_MYCBO / P0A5M9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
OTC_MYCTU / P9WIT9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P0A5M9 ornithine carbamoyltransferase (EC 2.1.3.3) from Mycobacterium tuberculosis variant bovis (see paper)
P9WIT9 ornithine carbamoyltransferase (EC 2.1.3.3) from Mycobacterium tuberculosis (see 2 papers)
34% identity, 97% coverage of query (186 bits)
ArgF / CAA45530.1 ornithine carbamoyltransferase from Mycobacterium tuberculosis variant bovis (see paper)
33% identity, 97% coverage of query (185 bits)
8qeuA / O50039 Crystal structure of ornithine transcarbamylase from arabidopsis thaliana (atotc) in complex with ornithine (see paper)
36% identity, 98% coverage of query (184 bits)
OTC / O50039 ornithine carbamoyltransferase (EC 2.1.3.3) from Arabidopsis thaliana (see 2 papers)
36% identity, 98% coverage of query (184 bits)
argF / CAB95016.1 ornithine carbamoyltransferase from Moritella profunda (see paper)
35% identity, 97% coverage of query (184 bits)
Q98BB6 ornithine carbamoyltransferase (EC 2.1.3.3) from Mesorhizobium loti (see paper)
37% identity, 94% coverage of query (184 bits)
OTC1A_PSESH / Q02047 Ornithine carbamoyltransferase 1, anabolic; OTCase 1; Ornithine carbamoyltransferase 1, phaseolotoxin-sensitive; SOCT; EC 2.1.3.3 from Pseudomonas savastanoi pv. phaseolicola (Pseudomonas syringae pv. phaseolicola) (see 2 papers)
35% identity, 96% coverage of query (181 bits)
OTC_MORAB / Q9K4Y9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Moritella abyssi (see paper)
argF / CAB95022.1 ornithine carbamoyltransferase from Moritella abyssi (see paper)
35% identity, 97% coverage of query (181 bits)
7np0A Crystal structure of mycobacterium tuberculosis argf in complex with (4-nitrophenyl)boronic acid.
34% identity, 97% coverage of query (180 bits)
7nnzB Crystal structure of mycobacterium tuberculosis argf in complex with 5-methyl-4-phenylthiazol-2-amine.
33% identity, 97% coverage of query (177 bits)
7novA Crystal structure of mycobacterium tuberculosis argf in complex with (4-methyl-3-nitrophenyl)boronic acid.
33% identity, 97% coverage of query (175 bits)
8qevA Crystal structure of ornithine transcarbamylase from arabidopsis thaliana (atotc) in complex with carbamoyl phosphate
35% identity, 98% coverage of query (175 bits)
arcB / Q48296 ArcB (EC 2.1.3.3) from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (see paper)
OTCC_HALSA / Q48296 Ornithine carbamoyltransferase, catabolic; cOTCase; EC 2.1.3.3 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
Q48296 ornithine carbamoyltransferase (EC 2.1.3.3) from Halobacterium salinarum (see paper)
arcB / CAA56906.1 ornithine transcarbamoylase from Halobacterium salinarum (see paper)
34% identity, 96% coverage of query (168 bits)
HSERO_RS07185 Ornithine carbamoyltransferase (EC 2.1.3.3) from Herbaspirillum seropedicae SmR1
34% identity, 96% coverage of query (162 bits)
ARG3 / P05150 ornithine carbamoyltransferase (EC 2.1.3.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
OTC_YEAST / P05150 Ornithine carbamoyltransferase; Ornithine transcarbamylase; OTCase; EC 2.1.3.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
32% identity, 94% coverage of query (159 bits)
argB / GI|168017 ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Emericella nidulans (see 5 papers)
34% identity, 94% coverage of query (157 bits)
Build an alignment for WP_011970089.1 and 63 homologs with ≥ 30% identity
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zmaT / C0JRF9 (S)-2,3-diaminopropanoate carbamoyltransferase from Bacillus cereus (see 2 papers)
29% identity, 96% coverage of query (119 bits)
argF' / Q8P8J2 acetylornithine transcarbamylase subunit (EC 2.1.3.9) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
AOTC_XANCP / Q8P8J2 N-acetylornithine carbamoyltransferase; N-acetyl-L-ornithine transcarbamylase; AOTCase; Acetylornithine transcarbamylase; EC 2.1.3.9 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 4 papers)
Q8P8J2 N-acetylornithine carbamoyltransferase (EC 2.1.3.9) from Xanthomonas campestris (see 2 papers)
27% identity, 98% coverage of query (109 bits)
3kzkA / Q8P8J2 Crystal structure of acetylornithine transcarbamylase complexed with acetylcitrulline (see paper)
27% identity, 98% coverage of query (109 bits)
3m4jA Crystal structure of n-acetyl-l-ornithine transcarbamylase complexed with palao
27% identity, 97% coverage of query (107 bits)
3kzoA Crystal structure of n-acetyl-l-ornithine transcarbamylase complexed with carbamyl phosphate and n-acetyl-l-norvaline
27% identity, 97% coverage of query (107 bits)
3kznA Crystal structure of n-acetyl-l-ornithine transcarbamylase complexed with n-acetyl-l-ornirthine
27% identity, 97% coverage of query (107 bits)
3kzmA Crystal structure of n-acetyl-l-ornithine transcarbamylase complexed with carbamyl phosphate
27% identity, 97% coverage of query (107 bits)
3l02A Crystal structure of n-acetyl-l-ornithine transcarbamylase e92a mutant complexed with carbamyl phosphate and n-succinyl-l-norvaline
27% identity, 97% coverage of query (106 bits)
1ml4A / P77918 The pala-liganded aspartate transcarbamoylase catalytic subunit from pyrococcus abyssi (see paper)
24% identity, 98% coverage of query (79.7 bits)
7zstB Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum in complex with fla-01
24% identity, 97% coverage of query (79.7 bits)
7zgsA Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with bound inhibitor 2-phenylethan-1-amine
23% identity, 80% coverage of query (78.2 bits)
7zidB Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum in complex with bda-14
24% identity, 97% coverage of query (78.2 bits)
7zeaB / A0A5K1K910 Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with bound inhibitor o-benzylhydroxylamine (see paper)
24% identity, 97% coverage of query (78.2 bits)
6fbaA Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with bound inhibitor 2,3-naphthalenediol
23% identity, 97% coverage of query (77.4 bits)
P20054 Multifunctional protein pyr1-3; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Dictyostelium discoideum (Social amoeba)
25% identity, 99% coverage of query (77.0 bits)
7zp2A Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum in complex with bda-04
24% identity, 97% coverage of query (76.3 bits)
7zhiA Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with bound inhibitor indole
24% identity, 97% coverage of query (76.3 bits)
7zczA Crystal structure of truncated aspartate transcarbamoylase from plasmodium falciparum with bound inhibitor 1-(4-chlorophenyl) methanamine
24% identity, 97% coverage of query (76.3 bits)
5g1pA Aspartate transcarbamoylase domain of human cad bound to carbamoyl phosphate
25% identity, 97% coverage of query (75.1 bits)
PYR1_MESAU / P08955 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster) (see 2 papers)
P08955 dihydroorotase (EC 3.5.2.3) from Mesocricetus auratus (see 2 papers)
24% identity, 99% coverage of query (72.0 bits)
5g1nE / P27708 Aspartate transcarbamoylase domain of human cad bound to pala (see paper)
24% identity, 99% coverage of query (72.0 bits)
CAD / P27708 CAD protein (EC 3.5.2.3; EC 6.3.5.5; EC 2.1.3.2) from Homo sapiens (see 6 papers)
PYR1_HUMAN / P27708 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human) (see 11 papers)
P27708 aspartate carbamoyltransferase (EC 2.1.3.2); dihydroorotase (EC 3.5.2.3); carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Homo sapiens (see 7 papers)
24% identity, 99% coverage of query (71.6 bits)
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Lawrence Berkeley National Laboratory