Searching for up to 100 curated homologs for WP_011975418.1 NCBI__GCF_000017145.1:WP_011975418.1 (1163 a.a.)
Found high-coverage hits (≥70%) to 36 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CarB / b0033 carbamoyl phosphate synthetase subunit β (EC 6.3.5.5) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
carB / P00968 carbamoyl-phosphate synthetase large subunit (EC 6.3.5.5) from Escherichia coli (strain K12) (see 7 papers)
CARB_ECOLI / P00968 Carbamoyl phosphate synthase large chain; Carbamoyl phosphate synthetase ammonia chain; EC 6.3.4.16; EC 6.3.5.5 from Escherichia coli (strain K12) (see 5 papers)
P00968 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Escherichia coli (see paper)
1bxrA / P00968 Structure of carbamoyl phosphate synthetase complexed with the atp analog amppnp (see paper)
carB carbamoyl phosphate synthase, large subunit; EC 6.3.5.5 from Escherichia coli (see 2 papers)
59% identity, 99% coverage of query (1306 bits)
1t36A Crystal structure of e. Coli carbamoyl phosphate synthetase small subunit mutant c248d complexed with uridine 5'-monophosphate
58% identity, 99% coverage of query (1280 bits)
1c3oA Crystal structure of the carbamoyl phosphate synthetase: small subunit mutant c269s with bound glutamine
58% identity, 99% coverage of query (1280 bits)
1ce8A Carbamoyl phosphate synthetase from escherichis coli with complexed with the allosteric ligand imp
58% identity, 99% coverage of query (1277 bits)
1a9xA Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis
58% identity, 99% coverage of query (1274 bits)
Q8RSS3 carbamoyl-phosphate synthase (glutamine-hydrolysing) (subunit 1/2) (EC 6.3.5.5) from Halomonas eurihalina (see paper)
58% identity, 100% coverage of query (1262 bits)
CARB_ARATH / Q42601 Carbamoyl phosphate synthase arginine-specific large chain, chloroplastic; CPS; CPSase; Ammonium-dependent carbamoyl phosphate synthetase; Arginine-specific carbamoyl phosphate synthetase, ammonia chain; Glutamine-dependent carbamoyl phosphate synthetase; Protein VENOSA 3; EC 6.3.4.16; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
54% identity, 100% coverage of query (1202 bits)
O50302 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Geobacillus stearothermophilus (see paper)
47% identity, 99% coverage of query (978 bits)
pyrAB / P25994 pyrimidine-specific carbamoyl-phosphate synthetase (large subunit) (EC 6.3.5.5) from Bacillus subtilis (strain 168) (see 4 papers)
CARB_BACSU / P25994 Carbamoyl phosphate synthase pyrimidine-specific large chain; Carbamoyl phosphate synthetase ammonia chain; EC 6.3.4.16; EC 6.3.5.5 from Bacillus subtilis (strain 168) (see paper)
45% identity, 99% coverage of query (972 bits)
B2G3Q3 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Streptococcus thermophilus (see paper)
46% identity, 98% coverage of query (946 bits)
pyrAb1 / CAJ75872.1 PyrAb1 protein from Lactobacillus plantarum subsp. plantarum (see paper)
44% identity, 100% coverage of query (913 bits)
carB / CAB56843.1 carbamoyl-phosphate synthase large subunit from Lactobacillus plantarum subsp. plantarum (see 3 papers)
42% identity, 88% coverage of query (735 bits)
P20054 Multifunctional protein pyr1-3; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Dictyostelium discoideum (Social amoeba)
37% identity, 98% coverage of query (733 bits)
pyrABCN protein pyrABCN [Includes glutamine-dependent carbamoyl-phosphate; Aspartate carbamoyltransferase]; EC 2.1.3.2; EC 6.3.5.5 from Emericella nidulans (see paper)
38% identity, 99% coverage of query (728 bits)
URA2 / P07259 carbamoyl phosphate synthase/aspartate carbamoyltransferase (EC 2.1.3.2; EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PYR1_YEAST / P07259 Multifunctional protein URA2; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 15 papers)
37% identity, 98% coverage of query (719 bits)
CAD / P27708 CAD protein (EC 3.5.2.3; EC 6.3.5.5; EC 2.1.3.2) from Homo sapiens (see 6 papers)
PYR1_HUMAN / P27708 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human) (see 11 papers)
P27708 aspartate carbamoyltransferase (EC 2.1.3.2); dihydroorotase (EC 3.5.2.3); carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Homo sapiens (see 7 papers)
38% identity, 94% coverage of query (715 bits)
PYR1_NEUCR / Q7S8A6 Multifunctional protein pyr-3; PyrABCN; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 6 papers)
36% identity, 99% coverage of query (714 bits)
PYR1_SCHPO / Q09794 Multifunctional protein ura1; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
ura1 / RF|NP_593055.1 carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5.5 from Schizosaccharomyces pombe (see 3 papers)
37% identity, 100% coverage of query (714 bits)
PYR1_MESAU / P08955 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster) (see 2 papers)
P08955 dihydroorotase (EC 3.5.2.3) from Mesocricetus auratus (see 2 papers)
38% identity, 95% coverage of query (714 bits)
BT3866 ammonium-dependent carbamoyl phosphate synthetase CarB2 (EC 6.3.4.16) from Bacteroides thetaiotaomicron VPI-5482
36% identity, 99% coverage of query (713 bits)
CPSM_RAT / P07756 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Rattus norvegicus (Rat) (see 2 papers)
36% identity, 99% coverage of query (707 bits)
CPSM_MOUSE / Q8C196 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Mus musculus (Mouse) (see 4 papers)
Q8C196 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Mus musculus (see 2 papers)
36% identity, 99% coverage of query (705 bits)
CPS1 / P31327 ammonia-dependent carbamoyl-phosphate synthase (EC 6.3.4.16) from Homo sapiens (see 4 papers)
CPSM_HUMAN / P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Homo sapiens (Human) (see 19 papers)
P31327 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Homo sapiens (see 10 papers)
36% identity, 99% coverage of query (696 bits)
CPA2 / P03965 carbamoyl phosphate synthetase (EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
CARB_YEAST / P03965 Carbamoyl phosphate synthase arginine-specific large chain; CPS; CPSase; CPSase-arg; Ammonium-dependent carbamoyl phosphate synthetase; Arginine-specific carbamoyl phosphate synthetase, ammonia chain; Carbamoyl phosphate synthase A; CPS-A; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.4.16; EC 6.3.5.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 10 papers)
39% identity, 92% coverage of query (692 bits)
PYR1_CAEEL / Q18990 Multifunctional protein pyr-1; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Caenorhabditis elegans (see 2 papers)
37% identity, 94% coverage of query (687 bits)
PYR1_SQUAC / Q91437 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Squalus acanthias (Spiny dogfish) (see paper)
36% identity, 95% coverage of query (687 bits)
O15830 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Trypanosoma cruzi (see paper)
38% identity, 96% coverage of query (686 bits)
O15829 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Leishmania mexicana (see paper)
38% identity, 97% coverage of query (685 bits)
CARB_NEUCR / Q7SH52 Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial; CPS; CPS-arg; CPSase; Ammonium-dependent carbamoyl phosphate synthetase; Arginine-specific carbamoyl phosphate synthetase, ammonia chain; Carbamoyl phosphate synthase A; CPS-A; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.4.16; EC 6.3.5.5 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 6 papers)
38% identity, 91% coverage of query (682 bits)
PYR1_DROME / P05990 Multifunctional protein r; Protein rudimentary; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Drosophila melanogaster (Fruit fly) (see paper)
36% identity, 94% coverage of query (681 bits)
5douD / P31327 Crystal structure of human carbamoyl phosphate synthetase i (cps1), ligand-bound form (see paper)
35% identity, 98% coverage of query (673 bits)
G4MS82 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Pyricularia oryzae (see paper)
36% identity, 95% coverage of query (663 bits)
CARB_SCHPO / O94313 Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial; CPS; CPSase; Ammonium-dependent carbamoyl phosphate synthetase; Arginine-specific carbamoyl phosphate synthetase, ammonia chain; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.4.16; EC 6.3.5.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
38% identity, 88% coverage of query (661 bits)
6w2jA Cps1 bound to allosteric inhibitor h3b-374
35% identity, 98% coverage of query (660 bits)
6w2jB / P31327 Cps1 bound to allosteric inhibitor h3b-374 (see paper)
36% identity, 76% coverage of query (548 bits)
6uelA / P31327 Cps1 bound to allosteric inhibitor h3b-193 (see paper)
35% identity, 76% coverage of query (515 bits)
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Lawrence Berkeley National Laboratory