Searching for up to 100 curated homologs for WP_011976260.1 NCBI__GCF_000017145.1:WP_011976260.1 (454 a.a.)
Found high-coverage hits (≥70%) to 76 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5dm3C / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
57% identity, 99% coverage of query (508 bits)
5dm3A / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
53% identity, 99% coverage of query (457 bits)
O33342 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis (see paper)
51% identity, 99% coverage of query (433 bits)
GLNA4_STRCO / O88070 Gamma-glutamylethanolamide synthetase GlnA4; EC 6.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 4 papers)
48% identity, 99% coverage of query (402 bits)
ipuC / Q936T0 γ-glutamylisopropylamide synthetase from Pseudomonas sp. (see paper)
IPUC_PSESP / Q936T0 Glutamate--isopropylamine ligase; Gamma-glutamylisopropylamide synthetase; GIPA synthetase; EC 6.3.2.- from Pseudomonas sp. (see paper)
35% identity, 98% coverage of query (266 bits)
GLNA1_METMA / Q8PY99 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
Q8PY99 glutamine synthetase (EC 6.3.1.2) from Methanosarcina mazei (see paper)
34% identity, 82% coverage of query (201 bits)
8tfkA Glutamine synthetase
34% identity, 82% coverage of query (201 bits)
8ufjB / Q8PY99 8ufjB (see paper)
34% identity, 82% coverage of query (199 bits)
P36205 glutamine synthetase (EC 6.3.1.2) from Thermotoga maritima (see paper)
32% identity, 85% coverage of query (198 bits)
GLNA3_HALMT / I3R176 Glutamine synthetase 3; GS3; Glutamate--ammonia ligase; EC 6.3.1.2 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
B8ZJH0 glutamine synthetase (EC 6.3.1.2) from Haloferax mediterranei (see paper)
34% identity, 82% coverage of query (196 bits)
8oooA Glutamine synthetase from methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and mgatp at 2.15 a resolution (see paper)
32% identity, 81% coverage of query (190 bits)
8ooqB Glutamine synthetase from Methanothermococcus thermolithotrophicus
32% identity, 81% coverage of query (190 bits)
GLNA_METJA / Q60182 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q60182 glutamine synthetase (EC 6.3.1.2) from Methanocaldococcus jannaschii (see paper)
34% identity, 82% coverage of query (189 bits)
GLNA_THET8 / Q5SIP0 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
35% identity, 82% coverage of query (186 bits)
Q0E5H7 glutamine synthetase (EC 6.3.1.2) from Halobacillus halophilus (see paper)
34% identity, 82% coverage of query (184 bits)
8oozA Glutamine synthetase
32% identity, 82% coverage of query (183 bits)
PS417_27140 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas simiae WCS417
31% identity, 95% coverage of query (182 bits)
8ooxB / A0A832VZP6 8ooxB (see paper)
32% identity, 82% coverage of query (180 bits)
AO356_13135 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2C3
31% identity, 97% coverage of query (179 bits)
C4L2T5 glutamine synthetase (EC 6.3.1.2) from Exiguobacterium sp. (see paper)
33% identity, 81% coverage of query (178 bits)
AO353_08595 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2E3
31% identity, 97% coverage of query (178 bits)
PfGW456L13_925 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens GW456-L13
31% identity, 97% coverage of query (178 bits)
BPHYT_RS23160 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Burkholderia phytofirmans PsJN
31% identity, 81% coverage of query (177 bits)
Pf1N1B4_2254 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N1B4
31% identity, 93% coverage of query (177 bits)
7tdpA Structure of paenibacillus polymyxa gs bound to met-sox-p-adp (transition state complex) to 1.98 angstom
32% identity, 81% coverage of query (177 bits)
GLN1B_STRCO / P15106 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
P15106 glutamine synthetase (EC 6.3.1.2) from Streptomyces coelicolor (see paper)
33% identity, 73% coverage of query (176 bits)
A0R079 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
33% identity, 73% coverage of query (175 bits)
Psest_4288 Glutamate--putrescine ligase (EC 6.3.1.11) from Pseudomonas stutzeri RCH2
30% identity, 97% coverage of query (174 bits)
7tfaB / A0A0F0G8G2 7tfaB (see paper)
32% identity, 81% coverage of query (174 bits)
GLN1A_BACSU / P12425 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Bacillus subtilis (strain 168) (see 9 papers)
P12425 glutamine synthetase (EC 6.3.1.2) from Bacillus subtilis (see 2 papers)
32% identity, 81% coverage of query (173 bits)
4s0rD / P12425 Structure of gs-tnra complex (see paper)
32% identity, 81% coverage of query (173 bits)
GLNA2_STRCO / Q9RDS6 Gamma-glutamylpolyamine synthetase GlnA2; EC 6.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 3 papers)
32% identity, 82% coverage of query (173 bits)
4lnkA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of gs-glutamate-amppcp complex
32% identity, 81% coverage of query (173 bits)
4lniA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
32% identity, 81% coverage of query (173 bits)
7tdvC / E3VXC2 7tdvC (see paper)
30% identity, 81% coverage of query (172 bits)
Pf6N2E2_4509 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) from Pseudomonas fluorescens FW300-N2E2
31% identity, 86% coverage of query (171 bits)
O85177 glutamine synthetase (EC 6.3.1.2) from Amycolatopsis mediterranei (see paper)
30% identity, 94% coverage of query (170 bits)
7tf6A Glutamine synthetase
30% identity, 81% coverage of query (170 bits)
7tf9S / A0A5D5GA79 L. Monocytogenes gs(14)-q-glnr peptide (see paper)
31% identity, 81% coverage of query (169 bits)
7tenA Glutamine synthetase
31% identity, 81% coverage of query (169 bits)
GLN1B_MYCBO / P0A591 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see 2 papers)
GLN1B_MYCTU / P9WN39 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 9 papers)
P0A591 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis variant bovis (see paper)
P9WN39 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis (see 12 papers)
33% identity, 73% coverage of query (168 bits)
1htoA / P9WN39 Crystallographic structure of a relaxed glutamine synthetase from mycobacterium tuberculosis (see paper)
33% identity, 73% coverage of query (168 bits)
4xycA Nanomolar inhibitors of mycobacterium tuberculosis glutamine synthetase 1: synthesis, biological evaluation and x-ray crystallographic studies
32% identity, 77% coverage of query (168 bits)
4acfA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with imidazopyridine inhibitor ((4-(6-bromo-3- (butylamino)imidazo(1,2-a)pyridin-2-yl)phenoxy) acetic acid) and l- methionine-s-sulfoximine phosphate.
33% identity, 73% coverage of query (168 bits)
3zxvA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl)pyridin-2-amine) and l- methionine-s-sulfoximine phosphate
33% identity, 73% coverage of query (168 bits)
3zxrA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1h-imidazol-4-yl)quinoline) and l-methionine-s- sulfoximine phosphate.
33% identity, 73% coverage of query (168 bits)
2bvcA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic
33% identity, 73% coverage of query (168 bits)
2whiA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a purine analogue inhibitor and l-methionine-s- sulfoximine phosphate.
33% identity, 73% coverage of query (168 bits)
A0R083 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
31% identity, 81% coverage of query (168 bits)
GMAS_METUF / F5RH07 Glutamate--methylamine ligase; Gamma-glutamylmethylamide synthetase; GMAS; EC 6.3.4.12 from Methyloversatilis universalis (strain ATCC BAA-1314 / DSM 25237 / JCM 13912 / CCUG 52030 / FAM5) (see paper)
30% identity, 98% coverage of query (167 bits)
P64246 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis variant bovis (see paper)
30% identity, 81% coverage of query (167 bits)
2wgsA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a purine analogue inhibitor.
33% identity, 73% coverage of query (167 bits)
P9WN37 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
30% identity, 81% coverage of query (167 bits)
GLNA_SULAC / Q9HH09 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q9HH09 glutamine synthetase (EC 6.3.1.2) from Sulfolobus acidocaldarius (see paper)
31% identity, 77% coverage of query (165 bits)
Build an alignment for WP_011976260.1 and 54 homologs with ≥ 30% identity
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GLNA_ARCFU / O29313 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
O29313 glutamine synthetase (EC 6.3.1.2) from Archaeoglobus fulgidus (see paper)
29% identity, 98% coverage of query (165 bits)
atdA1 / Q44249 N-glutaminylanilide synthase (EC 6.3.1.18) from Acinetobacter sp. (see paper)
ATDA1_ACISP / Q44249 Gamma-glutamylanilide synthase; Gamma-GA; Glutamine synthetase-like protein; EC 6.3.1.18 from Acinetobacter sp. (see paper)
32% identity, 82% coverage of query (163 bits)
8wwuB / A0A7Y1Q2L1 8wwuB
33% identity, 82% coverage of query (162 bits)
8wwvA Glutamine synthetase
33% identity, 82% coverage of query (162 bits)
GLN1B_SYNY3 / P77961 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P77961 glutamine synthetase (EC 6.3.1.2) from Synechocystis sp. (see paper)
32% identity, 77% coverage of query (158 bits)
3ng0A / P77961 Crystal structure of glutamine synthetase from synechocystis sp. Pcc 6803
32% identity, 77% coverage of query (157 bits)
5zlpJ / P94845 Crystal structure of glutamine synthetase from helicobacter pylori (see paper)
30% identity, 81% coverage of query (146 bits)
5zlpL Crystal structure of glutamine synthetase from helicobacter pylori
30% identity, 81% coverage of query (146 bits)
5zlpA Crystal structure of glutamine synthetase from helicobacter pylori
30% identity, 81% coverage of query (146 bits)
4s17A / A1A1Z1 The crystal structure of glutamine synthetase from bifidobacterium adolescentis atcc 15703
32% identity, 80% coverage of query (146 bits)
1fpyA Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor phosphinothricin
31% identity, 81% coverage of query (144 bits)
1f1hA / P0A1P6 Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions (see paper)
31% identity, 81% coverage of query (144 bits)
GLN1B_SALTY / P0A1P6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
P0A1P6 glutamine synthetase (EC 6.3.1.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
glnA glutamate--ammonia ligase; EC 6.3.1.2 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
31% identity, 81% coverage of query (141 bits)
YcjK / b1297 glutamate-putrescine ligase (EC 6.3.1.11) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
puuA / P78061 glutamate-putrescine ligase (EC 6.3.1.11) from Escherichia coli (strain K12) (see 3 papers)
PUUA_ECOLI / P78061 Gamma-glutamylputrescine synthetase PuuA; Gamma-Glu-Put synthetase; Glutamate--putrescine ligase; EC 6.3.1.11 from Escherichia coli (strain K12) (see 3 papers)
puuA / BAD88705.1 gamma-glutamylputrescine synthetase from Escherichia coli K-12 (see paper)
28% identity, 95% coverage of query (139 bits)
7cquA Gmas/adp/metsox-p complex
30% identity, 81% coverage of query (138 bits)
7cqqA Gmas in complex with amppnp and metsox
30% identity, 81% coverage of query (138 bits)
7cqnA Gmas in complex with amppcp
30% identity, 81% coverage of query (138 bits)
7cqwA / A0A369R1N0 Gmas/adp complex-conformation 1 (see paper)
30% identity, 81% coverage of query (138 bits)
P0A9C5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Escherichia coli (strain K12)
30% identity, 81% coverage of query (137 bits)
2lgsA Feedback inhibition of fully unadenylylated glutamine synthetase from salmonella typhimurium by glycine, alanine, and serine
31% identity, 81% coverage of query (134 bits)
1lgrA / P0A1P6 Interactions of nucleotides with fully unadenylylated glutamine synthetase from salmonella typhimurium (see paper)
31% identity, 81% coverage of query (134 bits)
4hppA / Q9HT65 Crystal structure of novel glutamine synthase homolog (see paper)
26% identity, 79% coverage of query (99.4 bits)
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Lawrence Berkeley National Laboratory