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Searching for up to 100 curated homologs for WP_011989078.1 NCBI__GCF_000016505.1:WP_011989078.1 (329 a.a.)

Found high-coverage hits (≥70%) to 61 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DCYD1_ARATH / F4HYF3 Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial; 1-aminocyclopropane-1-carboxylic acid deaminase 1; AtACD1; AtD-CDes1; D-CDes1; D-CDES; EC 3.5.99.7; EC 4.4.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
F4HYF3 D-cysteine desulfhydrase (EC 4.4.1.15) from Arabidopsis thaliana (see paper)
    44% identity, 97% coverage of query (240 bits)

B2MWN0 D-cysteine desulfhydrase (EC 4.4.1.15) from Solanum lycopersicum (see paper)
    41% identity, 97% coverage of query (238 bits)

DCYD1_ORYSJ / Q6ZHE5 D-cysteine desulfhydrase 1, mitochondrial; OsDCD1; OsD-CDes1; D-CDes1; EC 4.4.1.15 from Oryza sativa subsp. japonica (Rice) (see paper)
    40% identity, 96% coverage of query (235 bits)

YedO / b1919 D-cysteine desulfhydrase (EC 4.4.1.15; EC 4.5.1.2) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dcyD / P76316 D-cysteine desulfhydrase (EC 4.4.1.15; EC 4.5.1.2) from Escherichia coli (strain K12) (see 4 papers)
DCYD_ECOLI / P76316 D-cysteine desulfhydrase; EC 4.4.1.15 from Escherichia coli (strain K12) (see 2 papers)
dcyD / RF|NP_416429 D-cysteine desulfhydrase; EC 4.4.1.15 from Escherichia coli K12 (see 6 papers)
    40% identity, 96% coverage of query (221 bits)

cuyA / A3SQG3 L-cysteate sulfo-lyase (EC 4.4.1.25) from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) (see paper)
CUYA_ROSNI / A3SQG3 L-cysteate sulfo-lyase; EC 4.4.1.25 from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) (see paper)
    38% identity, 99% coverage of query (218 bits)

4d8uH / Q8ZNT7 Crystal structure of d-cysteine desulfhydrase from salmonella typhimurium at 3.3 a in monoclinic space group with 8 subunits in the asymmetric unit (see paper)
    38% identity, 96% coverage of query (214 bits)

Q8ZNT7 D-cysteine desulfhydrase (EC 4.4.1.15) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    38% identity, 96% coverage of query (214 bits)

4d9fA D-cysteine desulfhydrase from salmonella typhimurium complexed with d- cycloserine (dcs)
    38% identity, 96% coverage of query (214 bits)

4d9eA D-cysteine desulfhydrase from salmonella typhimurium complexed with l- cycloserine (lcs)
    38% identity, 96% coverage of query (214 bits)

4d9bA Pyridoxamine 5' phosphate (pmp) bound form of salmonella typhimurium d-cysteine desulfhydrase obtained after co-crystallization with d- cycloserine
    38% identity, 96% coverage of query (214 bits)

4d99A Salmonella typhimurium d-cysteine desulfhydrase with l-ser bound non- covalently at the active site
    38% identity, 96% coverage of query (214 bits)

4d97A Salmonella typhimurium d-cysteine desulfhydrase with d-ser bound at active site
    38% identity, 96% coverage of query (214 bits)

4d96A D-cysteine desulfhydrase from salmonella typhimurium complexed with 1- amino-1-carboxycyclopropane (acc)
    38% identity, 96% coverage of query (214 bits)

4d8wA Salmonella typhimurium d-cysteine desulfhydrase soaked with d-cys shows pyruvate bound 4 a away from active site
    38% identity, 96% coverage of query (214 bits)

O57809 L-serine ammonia-lyase (EC 4.3.1.17); D-Serine ammonia-lyase (EC 4.3.1.18) from Pyrococcus horikoshii (see paper)
1j0aA / O57809 Crystal structure analysis of the acc deaminase homologue (see paper)
    40% identity, 98% coverage of query (207 bits)

1j0bA Crystal structure analysis of the acc deaminase homologue complexed with inhibitor
    40% identity, 98% coverage of query (207 bits)

cuyA / Q5LL69 L-cysteate sulfo-lyase subunit (EC 4.4.1.25) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (see 2 papers)
CUYA_RUEPO / Q5LL69 L-cysteate sulfo-lyase; EC 4.4.1.25 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
    37% identity, 99% coverage of query (204 bits)

Q89XR6 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Bradyrhizobium japonicum (see paper)
    37% identity, 92% coverage of query (191 bits)

B8IP05 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Methylobacterium nodulans (see paper)
    34% identity, 96% coverage of query (191 bits)

B8R7S5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia silvatlantica (see paper)
    34% identity, 96% coverage of query (189 bits)

Q93AG0 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Rhizobium leguminosarum (see paper)
    35% identity, 95% coverage of query (187 bits)

B1M5C5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Methylobacterium radiotolerans (see paper)
    34% identity, 98% coverage of query (186 bits)

1tzmA Crystal structure of acc deaminase complexed with substrate analog b- chloro-d-alanine
    33% identity, 92% coverage of query (186 bits)

1tzkA Crystal structure of 1-aminocyclopropane-1-carboxylate-deaminase complexed with alpha-keto-butyrate
    33% identity, 92% coverage of query (186 bits)

1tzjA Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase complexed with d-vinyl glycine
    33% identity, 92% coverage of query (186 bits)

1tz2A Crystal structure of 1-aminocyclopropane-1-carboyxlate deaminase complexed with acc
    33% identity, 92% coverage of query (186 bits)

B2JYI5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phymatum (see paper)
    34% identity, 96% coverage of query (185 bits)

B8R7S8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia unamae (see paper)
    33% identity, 96% coverage of query (184 bits)

1A1D_PSEUD / Q00740 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Pseudomonas sp. (strain ACP) (see paper)
1rqxC / Q00740 Crystal structure of acc deaminase complexed with inhibitor (see paper)
    33% identity, 92% coverage of query (181 bits)

B8R7S7 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia terricola (see paper)
    33% identity, 92% coverage of query (180 bits)

B2TBV3 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phytofirmans (see paper)
    33% identity, 92% coverage of query (180 bits)

C5AQP6 D-cysteine desulfhydrase (EC 4.4.1.15) from Methylorubrum extorquens (see paper)
    32% identity, 99% coverage of query (179 bits)

B8R7S2 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia graminis (see paper)
    33% identity, 92% coverage of query (179 bits)

B8R7T2 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia xenovorans (see paper)
    32% identity, 92% coverage of query (179 bits)

B8R7S1 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia cepacia (see paper)
    32% identity, 96% coverage of query (177 bits)

B8R7S9 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia vietnamiensis (see paper)
    32% identity, 96% coverage of query (176 bits)

B8R7S3 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phenoliruptrix (see paper)
    33% identity, 92% coverage of query (176 bits)

B4EJA6 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia cenocepacia (see paper)
    32% identity, 96% coverage of query (176 bits)

1A1D_PSEPU / Q5PWZ8 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
Q5PWZ8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas putida (see 2 papers)
    33% identity, 95% coverage of query (174 bits)

B8R7R9 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia caledonica (see paper)
    32% identity, 92% coverage of query (174 bits)

D3U2Q8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Trichoderma asperellum (see paper)
    34% identity, 92% coverage of query (172 bits)

C3VP48 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas entomophila (see paper)
    32% identity, 92% coverage of query (171 bits)

G5AFQ7 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Phytophthora sojae (see paper)
    32% identity, 92% coverage of query (170 bits)

A8VU64 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Sinorhizobium sp. BL3 (see paper)
    32% identity, 95% coverage of query (169 bits)

1f2dA / Q7M523 1-aminocyclopropane-1-carboxylate deaminase (see paper)
    32% identity, 95% coverage of query (151 bits)

Q7M523 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Cyberlindnera saturnus (Yeast) (Williopsis saturnus)
    32% identity, 95% coverage of query (151 bits)

1j0eA Acc deaminase mutant reacton intermediate
    31% identity, 95% coverage of query (149 bits)

1j0dA Acc deaminase mutant complexed with acc
    31% identity, 95% coverage of query (149 bits)

Build an alignment

Build an alignment for WP_011989078.1 and 48 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

DCYD2_ARATH / A1L4V7 D-cysteine desulfhydrase 2, mitochondrial; AtD-CDes1; D-CDes1; EC 4.4.1.15 from Arabidopsis thaliana (Mouse-ear cress)
    24% identity, 91% coverage of query (89.0 bits)

A4VKI8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas stutzeri (see paper)
    25% identity, 99% coverage of query (85.5 bits)

nocJ / Q5J1R2 nocardicin C-9'-epimerase (EC 5.1.1.14) from Nocardia uniformis subsp. tsuyamanensis (see paper)
NOCJ_NOCUT / Q5J1R2 Nocardicin C-9' epimerase; Nocardicin-A epimerase; EC 5.1.1.14 from Nocardia uniformis subsp. tsuyamanensis (see paper)
    24% identity, 97% coverage of query (70.9 bits)

5ey5B Lbcats
    26% identity, 81% coverage of query (53.5 bits)

5tciH / P9WFX9 Crystal structure of tryptophan synthase from m. Tuberculosis - brd4592-bound form (see paper)
    23% identity, 71% coverage of query (50.8 bits)

6uapB Crystal structure of tryptophan synthase from m. Tuberculosis - open form with brd6309 bound
    23% identity, 71% coverage of query (50.8 bits)

6u6cB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk2-bound form
    23% identity, 71% coverage of query (50.8 bits)

5ocwB Structure of mycobacterium tuberculosis tryptophan synthase in space group f222
    23% identity, 71% coverage of query (50.8 bits)

6usaB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk1-bound form
    23% identity, 71% coverage of query (50.8 bits)

6dweB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and brd0059-bound form
    23% identity, 71% coverage of query (50.8 bits)

TRPB_MYCTU / P9WFX9 Tryptophan synthase beta chain; EC 4.2.1.20 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    23% identity, 71% coverage of query (50.4 bits)

TSB1 / P14671 tryptophan synthase, beta subunit (EC 4.2.1.122) from Arabidopsis thaliana (see 3 papers)
P14671 tryptophan synthase (EC 4.2.1.20) from Arabidopsis thaliana (see paper)
    25% identity, 77% coverage of query (47.8 bits)

TSB1 / AAA33490.1 tryptophan synthase beta-subunit, partial from Zea mays (see paper)
    25% identity, 77% coverage of query (46.6 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory