Searching for up to 100 curated homologs for WP_011989352.1 NCBI__GCF_000016505.1:WP_011989352.1 (344 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4grsA / Q8U0A9,Q9WYH8 Crystal structure of a chimeric dah7ps (see paper)
    53% identity, 96% coverage of query (355 bits)

Q9WYH8 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Thermotoga maritima (see paper)
3pg9A / Q9WYH8 Thermotoga maritima dah7p synthase in complex with inhibitor (see paper)
    52% identity, 97% coverage of query (351 bits)

1rzmA Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahps) from thermotoga maritima complexed with cd2+, pep and e4p
    52% identity, 97% coverage of query (351 bits)

1zcoB Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    56% identity, 74% coverage of query (296 bits)

1zcoA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    56% identity, 74% coverage of query (296 bits)

4c1kA Crystal structure of pyrococcus furiosus 3-deoxy-d-arabino- heptulosonate 7-phosphate synthase
    55% identity, 74% coverage of query (295 bits)

5j6fA / L8A208 Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
    55% identity, 74% coverage of query (290 bits)

3nvtA / Q8Y6T2 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
    55% identity, 74% coverage of query (284 bits)

3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate
    55% identity, 74% coverage of query (284 bits)

ccmA / BAA05463.1 32.4kD protein from Synechocystis sp. PCC 6803 (see paper)
    49% identity, 85% coverage of query (280 bits)

P39912 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54); chorismate mutase (EC 5.4.99.5) from Bacillus subtilis (see paper)
    53% identity, 76% coverage of query (279 bits)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168)
    53% identity, 76% coverage of query (279 bits)

1vs1D / Q9YEJ7 Crystal structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase) from aeropyrum pernix in complex with mn2+ and pep
    56% identity, 72% coverage of query (244 bits)

Q9YEJ7 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Aeropyrum pernix (see paper)
    56% identity, 72% coverage of query (244 bits)

CA265_RS11635 chorismate mutase (EC 5.4.99.5); 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54) from Pedobacter sp. GW460-11-11-14-LB5
    30% identity, 71% coverage of query (120 bits)

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Build an alignment for WP_011989352.1 and 15 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Echvi_0120 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase / chorismate mutase (EC 2.5.1.54; EC 5.4.99.5) from Echinicola vietnamensis KMM 6221, DSM 17526
    28% identity, 71% coverage of query (119 bits)

Q9ZE84 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Rickettsia prowazekii (see paper)
    28% identity, 72% coverage of query (95.5 bits)

Q9ZN55 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Helicobacter pylori (see paper)
    28% identity, 72% coverage of query (83.2 bits)

Q9JZ55 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Neisseria meningitidis serogroup B (see paper)
    26% identity, 73% coverage of query (81.6 bits)

P45251 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Haemophilus influenzae (see paper)
    25% identity, 74% coverage of query (81.3 bits)

Q9ZFK4 3-deoxy-8-phosphooctulonate synthase (EC 2.5.1.55) from Pseudomonas aeruginosa (see paper)
    24% identity, 72% coverage of query (76.6 bits)

3fyoD / Q9JZ55 Crystal structure of the triple mutant (n23c/d247e/p249a) of 3-deoxy- d-manno-octulosonate 8-phosphate synthase (kdo8ps) from neisseria meningitidis (see paper)
    24% identity, 73% coverage of query (70.9 bits)

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