Searching for up to 100 curated homologs for WP_012042286.1 NCBI__GCF_000015165.1:WP_012042286.1 (213 a.a.)
Found high-coverage hits (≥70%) to 13 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lgnG / BAM68210.1 2-keto-3-deoxy-6-phosphogalactonate aldolase lgnG from Paracoccus laeviglucosivorans (see 2 papers)
52% identity, 98% coverage of query (215 bits)
DGOA_RHIME / Q92RN8 Probable 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
57% identity, 98% coverage of query (215 bits)
YidU / b4477 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55; EC 4.1.2.21) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dgoA / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55) from Escherichia coli (strain K12) (see 5 papers)
DGOA_ECOLI / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Escherichia coli (strain K12) (see 3 papers)
Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.21) from Escherichia coli (see paper)
dgoA / RF|YP_026238 2-dehydro-3-deoxy-6-phosphogalactonate aldolase from Escherichia coli K12 (see 2 papers)
46% identity, 97% coverage of query (167 bits)
2v82A / Q6BF16 Kdpgal complexed to kdpgal (see paper)
46% identity, 96% coverage of query (167 bits)
TM0066 / Q9WXS1 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16; EC 4.1.2.55) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
36% identity, 90% coverage of query (115 bits)
1wa3D / Q9WXS1 Mechanism of the class i kdpg aldolase (see paper)
36% identity, 90% coverage of query (115 bits)
D4GV57 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Haloferax volcanii (see paper)
33% identity, 74% coverage of query (87.0 bits)
ALKH_BACSU / P50846 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Bacillus subtilis (strain 168) (see paper)
32% identity, 80% coverage of query (79.3 bits)
CA265_RS19860 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Pedobacter sp. GW460-11-11-14-LB5
33% identity, 74% coverage of query (68.9 bits)
Build an alignment for WP_012042286.1 and 9 homologs with ≥ 30% identity
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3vcrA / D2YW47 Crystal structure of a putative kdpg (2-keto-3-deoxy-6- phosphogluconate) aldolase from oleispira antarctica (see paper)
27% identity, 80% coverage of query (63.9 bits)
kdgA / P38448 2-dehydro-3-deoxy-D-gluconate-6-phosphate aldolase (EC 4.1.2.55) from Dickeya dadantii (strain 3937) (see 2 papers)
32% identity, 71% coverage of query (58.5 bits)
ALKD_PSEA6 / Q15X88 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phospho-D-gluconate aldolase; KDPG aldolase; EC 4.1.2.14 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
27% identity, 74% coverage of query (55.8 bits)
P00885 2-dehydro-3-deoxy-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase; EC 4.1.2.14 from Pseudomonas putida (Arthrobacter siderocapsulatus)
29% identity, 76% coverage of query (53.5 bits)
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Lawrence Berkeley National Laboratory