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Searching for up to 100 curated homologs for WP_012102436.1 NCBI__GCF_000016505.1:WP_012102436.1 (318 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
    43% identity, 98% coverage of query (258 bits)

GAE4 / O22141 subunit of UDP-GlcA 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
GAE4_ARATH / O22141 UDP-glucuronate 4-epimerase 4; UDP-glucuronic acid epimerase 4; AtUGlcAE1; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O22141 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 4 papers)
    41% identity, 97% coverage of query (243 bits)

5u4qA 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
    39% identity, 98% coverage of query (242 bits)

LPSL_RHIME / O54067 Probable UDP-glucuronate 4-epimerase; UDP-glucuronic acid epimerase; EC 5.1.3.6 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    35% identity, 97% coverage of query (241 bits)

UGA4E_RHIR8 / B9J8R3 UDP-glucuronate 4-epimerase; UGA4E; ArUGAE; EC 5.1.3.6 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter)
    37% identity, 97% coverage of query (241 bits)

GAE2_ARATH / Q9LPC1 UDP-glucuronate 4-epimerase 2; UDP-glucuronic acid epimerase 2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LPC1 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
    39% identity, 99% coverage of query (240 bits)

GAE3_ARATH / O81312 UDP-glucuronate 4-epimerase 3; UDP-glucuronic acid epimerase 3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O81312 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see paper)
    40% identity, 97% coverage of query (239 bits)

gla / P96481 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Streptococcus pneumoniae (see 2 papers)
    39% identity, 98% coverage of query (237 bits)

Q6K9M5 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Oryza sativa (see paper)
    41% identity, 97% coverage of query (231 bits)

GAE1_ARATH / Q9M0B6 UDP-glucuronate 4-epimerase 1; UDP-glucuronic acid epimerase 1; AtUGlcAE3; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9M0B6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
    40% identity, 97% coverage of query (230 bits)

Q304Y2 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Zea mays (see paper)
    40% identity, 97% coverage of query (228 bits)

GAE6_ARATH / Q9LIS3 UDP-glucuronate 4-epimerase 6; UDP-glucuronic acid epimerase 6; AtUGlcAE2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LIS3 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
    38% identity, 97% coverage of query (227 bits)

5u4qB 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
    38% identity, 98% coverage of query (224 bits)

6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
    41% identity, 97% coverage of query (223 bits)

6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
    41% identity, 97% coverage of query (223 bits)

6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
    41% identity, 97% coverage of query (223 bits)

GAE5_ARATH / Q9STI6 UDP-glucuronate 4-epimerase 5; UDP-glucuronic acid epimerase 5; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9STI6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 2 papers)
    39% identity, 97% coverage of query (221 bits)

6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
    41% identity, 97% coverage of query (221 bits)

A0A1J0KK43 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Albuca bracteata (see paper)
    38% identity, 98% coverage of query (214 bits)

Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
    35% identity, 97% coverage of query (177 bits)

Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
    32% identity, 98% coverage of query (161 bits)

1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
    32% identity, 98% coverage of query (161 bits)

wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
    32% identity, 98% coverage of query (159 bits)

tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
    31% identity, 98% coverage of query (159 bits)

6kvcA Moee5 in complex with udp-glucose and NAD
    31% identity, 97% coverage of query (156 bits)

6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
    31% identity, 97% coverage of query (154 bits)

GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    34% identity, 97% coverage of query (152 bits)

gdh / Q54116 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Saccharopolyspora erythraea (see 2 papers)
    30% identity, 98% coverage of query (151 bits)

6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
    30% identity, 98% coverage of query (149 bits)

6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
    30% identity, 98% coverage of query (149 bits)

Build an alignment

Build an alignment for WP_012102436.1 and 30 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

galE / P55180 UDP-glucose 4-epimerase (EC 5.1.3.7; EC 5.1.3.2) from Bacillus subtilis (strain 168) (see 5 papers)
galE / CAA67713.1 UDP-glucose 4-epimerase from Bacillus subtilis (see paper)
    28% identity, 98% coverage of query (148 bits)

A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
    31% identity, 96% coverage of query (148 bits)

UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
    29% identity, 99% coverage of query (147 bits)

UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
    29% identity, 99% coverage of query (147 bits)

2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
    29% identity, 99% coverage of query (147 bits)

3vpsA / E5KJ94 Structure of a novel NAD dependent-ndp-hexosamine 5,6-dehydratase, tuna, involved in tunicamycin biosynthesis
    30% identity, 97% coverage of query (146 bits)

tunA / E5KJ94 UDP-N-acetyl-α-D-glucosamine 5,6-dehydratase from Streptomyces chartreusis (see paper)
    30% identity, 97% coverage of query (146 bits)

RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    31% identity, 98% coverage of query (145 bits)

8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
    30% identity, 97% coverage of query (145 bits)

Q8LNZ3 UDP-glucose 4-epimerase (EC 5.1.3.2) from Oryza sativa Japonica Group (see paper)
    27% identity, 98% coverage of query (144 bits)

ravE / D1H0J1 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces ravidus (see 2 papers)
    31% identity, 97% coverage of query (144 bits)

1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
    29% identity, 97% coverage of query (144 bits)

1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
    29% identity, 97% coverage of query (144 bits)

1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
    29% identity, 97% coverage of query (144 bits)

UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
    28% identity, 100% coverage of query (143 bits)

6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
    31% identity, 99% coverage of query (142 bits)

A0A0H2UQY4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Streptococcus pneumoniae (see paper)
    29% identity, 97% coverage of query (142 bits)

uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
    30% identity, 99% coverage of query (142 bits)

GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
    29% identity, 97% coverage of query (142 bits)

2udpA Udp-galactose 4-epimerase complexed with udp-phenol
    29% identity, 97% coverage of query (142 bits)

1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
    29% identity, 97% coverage of query (142 bits)

gdh / Q93EK0 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Saccharopolyspora spinosa (see 2 papers)
    30% identity, 98% coverage of query (141 bits)

6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
    29% identity, 96% coverage of query (141 bits)

TGDS_HUMAN / O95455 dTDP-D-glucose 4,6-dehydratase; EC 4.2.1.46 from Homo sapiens (Human) (see paper)
    31% identity, 98% coverage of query (141 bits)

7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
    32% identity, 97% coverage of query (141 bits)

galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
    32% identity, 97% coverage of query (141 bits)

7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
    32% identity, 97% coverage of query (141 bits)

6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
    29% identity, 96% coverage of query (141 bits)

7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
    32% identity, 97% coverage of query (141 bits)

3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
    33% identity, 99% coverage of query (140 bits)

8wovB / Q9T0A7 Crystal structure of arabidopsis thaliana udp-glucose 4-epimerase 2 (atuge2) complexed with udp, g233a mutant (see paper)
    27% identity, 97% coverage of query (140 bits)

UGE2_ARATH / Q9T0A7 UDP-glucose 4-epimerase 2; AtUGE2; UDP-galactose 4-epimerase 2; EC 5.1.3.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9T0A7 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 2 papers)
    27% identity, 97% coverage of query (140 bits)

1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
    29% identity, 97% coverage of query (140 bits)

3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
    33% identity, 99% coverage of query (140 bits)

3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
    33% identity, 99% coverage of query (140 bits)

wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
    33% identity, 99% coverage of query (139 bits)

RHM3 / Q9LH76 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM3 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM3_ARATH / Q9LH76 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3; Probable rhamnose biosynthetic enzyme 3; AtRHM3; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 98% coverage of query (139 bits)

gnu / Q4KXC7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli (see paper)
    31% identity, 97% coverage of query (139 bits)

Q5D9E1 UDP-glucose 4-epimerase (EC 5.1.3.2) from Schistosoma japonicum (see paper)
    30% identity, 97% coverage of query (139 bits)

Q58IJ6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Hordeum vulgare (see paper)
    27% identity, 98% coverage of query (139 bits)

1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
    29% identity, 97% coverage of query (139 bits)

7xpoA / C0HI30 Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glc (see paper)
    27% identity, 98% coverage of query (138 bits)

GALE_DROME / Q9W0P5 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Drosophila melanogaster (Fruit fly) (see 2 papers)
Q9W0P5 UDP-glucose 4-epimerase (EC 5.1.3.2) from Drosophila melanogaster (see paper)
    29% identity, 97% coverage of query (138 bits)

7xpqA Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glcnac
    27% identity, 98% coverage of query (138 bits)

UGE1_PEA / B0M3E8 Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 1; UDP-D-xylose 4-epimerase; UDP-L-arabinose 4-epimerase; UDP-galactose 4-epimerase 1; UDP-glucose 4-epimerase 1; PsUGE1; EC 5.1.3.2; EC 5.1.3.5 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
B0M3E8 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-arabinose 4-epimerase (EC 5.1.3.5) from Pisum sativum (see paper)
    28% identity, 97% coverage of query (137 bits)

GALE_BIFL2 / E8MF10 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) (see paper)
lnpD / GB|BAF73927.1 UDP-glucose 4-epimerase; EC 5.1.3.2 from Bifidobacterium longum subsp. longum JCM 1217 (see paper)
    29% identity, 98% coverage of query (137 bits)

8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
    30% identity, 97% coverage of query (137 bits)

8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
    30% identity, 97% coverage of query (137 bits)

1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
    28% identity, 97% coverage of query (137 bits)

RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
    30% identity, 98% coverage of query (136 bits)

1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
    28% identity, 97% coverage of query (136 bits)

3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
    30% identity, 96% coverage of query (136 bits)

6k0iA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glc
    29% identity, 97% coverage of query (135 bits)

6k0hA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glcnac
    29% identity, 97% coverage of query (135 bits)

6k0gA / E8MF10 Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp (see paper)
    29% identity, 97% coverage of query (135 bits)

1hzjA Human udp-galactose 4-epimerase: accommodation of udp-n- acetylglucosamine within the active site
    27% identity, 97% coverage of query (130 bits)

1i3lA Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase
    27% identity, 97% coverage of query (129 bits)

1i3kA / Q14376 Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase (see paper)
    27% identity, 97% coverage of query (129 bits)

GALE / Q14376 UDP-galactose 4-epimerase (EC 5.1.3.2; EC 5.1.3.7) from Homo sapiens (see 6 papers)
GALE_HUMAN / Q14376 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Homo sapiens (Human) (see 12 papers)
Q14376 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Homo sapiens (see 4 papers)
    27% identity, 97% coverage of query (129 bits)

1ek6A Structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
    27% identity, 97% coverage of query (129 bits)

2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
    30% identity, 97% coverage of query (129 bits)

4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
    26% identity, 99% coverage of query (127 bits)

8du1A / A0A077ELH2 Crystal structure of NAD bound dtdp-glucose 4,6-dehydratase from elizabethkingia anophelis
    28% identity, 99% coverage of query (127 bits)

6vloA / Q5UR12 X-ray structure of the r141 sugar 4,6-dehydratase from acanthamoeba polyphaga minivirus (see paper)
    33% identity, 83% coverage of query (125 bits)

2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
    29% identity, 97% coverage of query (125 bits)

4lk3C Crystal structure of human udp-xylose synthase r236a substitution
    26% identity, 99% coverage of query (124 bits)

GALE_CAEEL / Q564Q1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Caenorhabditis elegans (see paper)
    26% identity, 97% coverage of query (124 bits)

6bi4B 2.9 angstrom resolution crystal structure of dtdp-glucose 4,6- dehydratase (rfbb) from bacillus anthracis str. Ames in complex with NAD.
    26% identity, 97% coverage of query (123 bits)

6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
    31% identity, 97% coverage of query (122 bits)

6bi4C / A0A6L7HMN5 2.9 angstrom resolution crystal structure of dtdp-glucose 4,6- dehydratase (rfbb) from bacillus anthracis str. Ames in complex with NAD. (see paper)
    27% identity, 97% coverage of query (122 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory