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Searching for up to 100 curated homologs for WP_012116019.1 NCBI__GCF_000017645.1:WP_012116019.1 (273 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.17.2 / O85765 SsuC, component of Aromatic sulfonate porter from Pseudomonas putida (see paper)
    39% identity, 93% coverage of query (160 bits)

TauC / b0367 taurine ABC transporter membrane subunit (EC 7.6.2.7) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
TauC / Q47539 taurine ABC transporter membrane subunit (EC 7.6.2.7) from Escherichia coli (strain K12) (see 2 papers)
TAUC_ECOLI / Q47539 Taurine transport system permease protein TauC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.17.1 / Q47539 TauC aka SSIC aka B0367, component of Taurine (2-aminoethane sulfonate) porter from Escherichia coli (see 4 papers)
    34% identity, 98% coverage of query (158 bits)

SsuC / b0934 aliphatic sulfonate ABC transporter membrane subunit (EC 7.6.2.14) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SsuC / P75851 aliphatic sulfonate ABC transporter membrane subunit (EC 7.6.2.14) from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.17.10 / P75851 Putative aliphatic sulfonates transport permease protein SsuC, component of Aliphatic sulfonate (alkanesulfonate) import permease, SsuABC (YcbOEM) and is regluated by the transcriptional activator, Cbl from Escherichia coli (strain K12)
    36% identity, 93% coverage of query (139 bits)

CMPB_SYNE7 / Q55106 Bicarbonate transport system permease protein CmpB from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.3 / Q55106 CmpB, component of Bicarbonate porter (activated by low [CO2] mediated by CmpR; (Nishimura et al., 2008)) (see 2 papers)
    31% identity, 96% coverage of query (120 bits)

TC 3.A.1.17.4 / Q2BM70 Putative taurine uptake ABC transporter permease protein, component of The taurine uptake system, TauABC from Neptuniibacter caesariensis
    34% identity, 96% coverage of query (117 bits)

TC 3.A.1.16.4 / Q8YRV7 ABC nitrate transport permease protein, component of Nitrate uptake system, NrtABCD from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
    32% identity, 84% coverage of query (114 bits)

8wm8B / Q8YZ77 Cryo-em structure of cyanobacterial nitrate/nitrite transporter nrtbcd in complex with nitrate (see paper)
    33% identity, 87% coverage of query (113 bits)

AZOBR_RS18555 ABC transporter for nitrate, permease component from Azospirillum brasilense Sp245
    32% identity, 74% coverage of query (109 bits)

Ac3H11_2561 ABC transporter for L-Histidine, permease component 2 from Acidovorax sp. GW101-3H11
    33% identity, 94% coverage of query (100 bits)

RIBX_CHLAA / A9WGD1 Riboflavin transport system permease protein RibX from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
TC 3.A.1.17.14 / A9WGD1 Riboflavin transport system permease protein RibX, component of Riboflavin uptake porter, RibXY (RibX, 168 aas and 6 TMSs; RibY, 351 aas) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
    31% identity, 91% coverage of query (98.2 bits)

OUSW_DICD3 / E0SCY2 Glycine betaine/choline transport system permease protein OusW from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    32% identity, 71% coverage of query (82.8 bits)

Build an alignment

Build an alignment for WP_012116019.1 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

A0A077T980 ABC-type quaternary amine transporter (subunit 3/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    29% identity, 71% coverage of query (78.2 bits)

Q7DAU8 ABC-type quaternary amine transporter (EC 7.6.2.9) from Lactococcus lactis (see paper)
    27% identity, 72% coverage of query (69.7 bits)

TC 3.A.1.12.5 / Q9RQ05 BusAB aka OPUABC, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis (see 2 papers)
    26% identity, 71% coverage of query (67.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory