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Searching for up to 100 curated homologs for WP_012171581.1 NCBI__GCF_000010525.1:WP_012171581.1 (459 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DUG1_SCHPO / Q9P6I2 Cys-Gly metallodipeptidase dug1; GSH degradosomal complex subunit DUG1; EC 3.4.13.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
    31% identity, 99% coverage of query (232 bits)

Build an alignment

Build an alignment for WP_012171581.1 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

CNDP2_HUMAN / Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human) (see 5 papers)
Q96KP4 cytosol nonspecific dipeptidase (EC 3.4.13.18) from Homo sapiens (see 2 papers)
    29% identity, 98% coverage of query (211 bits)

4mmoA / Q97V97 The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
    33% identity, 95% coverage of query (209 bits)

CNDP2_RAT / Q6Q0N1 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Threonyl dipeptidase; EC 3.4.13.18 from Rattus norvegicus (Rat) (see 2 papers)
    28% identity, 98% coverage of query (208 bits)

2zofA / Q9D1A2 Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
    28% identity, 98% coverage of query (207 bits)

CNDP2_MOUSE / Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 3 papers)
    28% identity, 98% coverage of query (207 bits)

2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin
    28% identity, 98% coverage of query (207 bits)

Q9RSV5 nucleoside deoxyribosyltransferase (EC 2.4.2.6) from Lactobacillus leichmannii (see paper)
    34% identity, 97% coverage of query (192 bits)

Q8MT58 cytosol nonspecific dipeptidase (EC 3.4.13.18) from Drosophila melanogaster (see paper)
    29% identity, 96% coverage of query (192 bits)

Q3LHN4 Xaa-methyl-His dipeptidase (EC 3.4.13.5) from Oreochromis niloticus (see 2 papers)
    27% identity, 98% coverage of query (185 bits)

4g1pA / P43616 Structural and mechanistic basis of substrate recognition by novel di- peptidase dug1p from saccharomyces cerevisiae
    27% identity, 98% coverage of query (185 bits)

CNDP1 / Q96KN2 Beta-Ala-His dipeptidase (EC 3.4.13.20) from Homo sapiens (see 2 papers)
CNDP1_HUMAN / Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
Q96KN2 beta-Ala-His dipeptidase (EC 3.4.13.20) from Homo sapiens (see 5 papers)
    27% identity, 98% coverage of query (185 bits)

DUG1 / P43616 Cys-Gly metallodipeptidase (EC 3.4.13.18) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
DUG1_YEAST / P43616 Cys-Gly metallodipeptidase DUG1; Deficient in utilization of glutathione protein 1; GSH degradosomal complex subunit DUG1; EC 3.4.13.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    27% identity, 98% coverage of query (185 bits)

A4F1S8 Xaa-methyl-His dipeptidase (EC 3.4.13.5) from Anguilla japonica (see paper)
    28% identity, 98% coverage of query (181 bits)

3dljA / Q96KN2 Crystal structure of human carnosine dipeptidase 1
    27% identity, 98% coverage of query (180 bits)

CNDP1_RAT / Q66HG3 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; EC 3.4.13.20 from Rattus norvegicus (Rat) (see paper)
    26% identity, 97% coverage of query (178 bits)

CNDP1_MOUSE / Q8BUG2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; EC 3.4.13.20 from Mus musculus (Mouse) (see 3 papers)
Q8BUG2 beta-Ala-His dipeptidase (EC 3.4.13.20) from Mus musculus (see paper)
    27% identity, 97% coverage of query (176 bits)

tpdA / B2KZE7 cysteinylglycine-(S) conjugate dipeptidase (EC 3.4.13.23) from Corynebacterium striatum (see 3 papers)
TPDA_CORST / B2KZE7 Cysteinylglycine-S-conjugate dipeptidase; Thiol precursor dipeptidase; EC 3.4.13.23 from Corynebacterium striatum (see paper)
B2KZE7 cysteinylglycine-S-conjugate dipeptidase (EC 3.4.13.23) from Corynebacterium striatum (see paper)
    30% identity, 85% coverage of query (129 bits)

DUG2 / P38149 Deficient in Utilization of Glutathione from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
DUG2_YEAST / P38149 Probable di- and tripeptidase DUG2; Deficient in utilization of glutathione protein 2; GSH degradosomal complex subunit DUG2; EC 3.4.-.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    22% identity, 86% coverage of query (115 bits)

3pfeA / Q5ZXC3 Crystal structure of a m20a metallo peptidase (dape, lpg0809) from legionella pneumophila subsp. Pneumophila str. Philadelphia 1 at 1.50 a resolution
    27% identity, 96% coverage of query (105 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory