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Searching for up to 100 curated homologs for WP_012277178.1 NCBI__GCF_000019185.1:WP_012277178.1 (307 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

tesF / Q83VZ4 propanal dehydrogenase (EC 1.2.1.87) from Comamonas testosteroni (see 2 papers)
    80% identity, 94% coverage of query (479 bits)

nahO / AAX38569.1 NahO from Pseudomonas putida (see paper)
    77% identity, 95% coverage of query (473 bits)

nahO / AAA89106.1 acetaldehyde dehydrogenase (acylating) from Pseudomonas putida (see paper)
    76% identity, 95% coverage of query (468 bits)

nahO / BAE92171.1 acetaldehyde dehydrogenase NahO from Pseudomonas putida (see 2 papers)
    76% identity, 95% coverage of query (468 bits)

ACDH4_PARXL / Q79AF6 Acetaldehyde dehydrogenase 4; Acetaldehyde dehydrogenase [acetylating] 4; Propanal dehydrogenase (CoA-propanoylating); EC 1.2.1.10; EC 1.2.1.87 from Paraburkholderia xenovorans (strain LB400) (see 2 papers)
Q79AF6 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10); propanal dehydrogenase (CoA-propanoylating) (EC 1.2.1.87) from Paraburkholderia xenovorans (see 2 papers)
bphJ / CAA54035.1 acetaldehyde dehydrogenase (acylating) from Paraburkholderia xenovorans LB400 (see paper)
    75% identity, 95% coverage of query (466 bits)

hsaG / P9WQH3 propanal dehydrogenase (EC 1.2.1.87) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
ACDH_MYCTU / P9WQH3 Propanal dehydrogenase (CoA-propanoylating); Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.87; EC 1.2.1.10 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    58% identity, 95% coverage of query (346 bits)

hsaG / Q0S816 propanal dehydrogenase (EC 1.2.1.87) from Rhodococcus jostii (strain RHA1) (see paper)
    56% identity, 95% coverage of query (340 bits)

ACDH_THET8 / Q53WH9 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; Propanal dehydrogenase (CoA-propanoylating); Propanaldehyde dehydrogenase; EC 1.2.1.10; EC 1.2.1.87 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
Q53WH9 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10); propanal dehydrogenase (CoA-propanoylating) (EC 1.2.1.87) from Thermus thermophilus (see 2 papers)
    57% identity, 95% coverage of query (330 bits)

4lrtB / D1A3K7 Crystal and solution structures of the bifunctional enzyme (aldolase/aldehyde dehydrogenase) from thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and coa accommodation whithin the shared cofactor-binding site
    56% identity, 93% coverage of query (328 bits)

4lrsB Crystal and solution structures of the bifunctional enzyme (aldolase/aldehyde dehydrogenase) from thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and coa accommodation whithin the shared cofactor-binding site
    56% identity, 93% coverage of query (328 bits)

cbzQ / AAX50131.1 CbzQ from Pseudomonas putida (see paper)
    55% identity, 95% coverage of query (325 bits)

cmtH / AAB62294.1 acetaldehyde dehydrogenase from Pseudomonas putida (see 3 papers)
    57% identity, 93% coverage of query (325 bits)

ACDH_PSESP / Q9KWS1 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Pseudomonas sp. (see paper)
    55% identity, 93% coverage of query (324 bits)

carF / BAC41555.1 Acetaldehyde dehydrogenase from Pseudomonas resinovorans (see 9 papers)
    55% identity, 96% coverage of query (322 bits)

MhpF / b0351 acetaldehyde dehydrogenase (acetylating) MhpF (EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
mhpF / P77580 acetaldehyde dehydrogenase (acetylating) MhpF (EC 1.2.1.10) from Escherichia coli (strain K12) (see 11 papers)
ACDH_ECOLI / P77580 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Escherichia coli (strain K12) (see paper)
mhpF / GB|AAZ87107.1 acetaldehyde dehydrogenase; EC 1.2.1.10 from Escherichia coli K12 (see 4 papers)
    56% identity, 94% coverage of query (319 bits)

todI / Q51949 acylating aldehyde dehydrogenase (EC 1.2.1.10) from Pseudomonas putida (see paper)
todI / AAA61943.1 acylating aldehyde dehydrogenase from Pseudomonas putida (see paper)
    56% identity, 95% coverage of query (318 bits)

dmpF / Q52060 acetaldehyde dehydrogenase (acylating) (EC 1.2.1.10) from Pseudomonas sp. (strain CF600) (see paper)
ACDH_PSEUF / Q52060 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Pseudomonas sp. (strain CF600) (see 3 papers)
Q52060 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Pseudomonas sp. (see paper)
1nvmB / Q52060 Crystal structure of a bifunctional aldolase-dehydrogenase : sequestering a reactive and volatile intermediate (see paper)
dmpF / CAA43226.1 acetaldehyde dehydrogenase (acylating) from Pseudomonas sp. CF600 (see paper)
    57% identity, 95% coverage of query (316 bits)

nikA / CAB46531.1 NikA protein from Streptomyces tendae (see paper)
    36% identity, 95% coverage of query (172 bits)

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Build an alignment for WP_012277178.1 and 18 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory