Searching for up to 100 curated homologs for WP_012277825.1 NCBI__GCF_000019185.1:WP_012277825.1 (294 a.a.)
Found high-coverage hits (≥70%) to 65 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5h3hB Esterase (eaest) from exiguobacterium antarcticum (see paper)
24% identity, 96% coverage of query (76.6 bits)
EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
23% identity, 95% coverage of query (76.3 bits)
cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
24% identity, 96% coverage of query (75.1 bits)
ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
25% identity, 97% coverage of query (73.9 bits)
3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
25% identity, 97% coverage of query (73.9 bits)
8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
25% identity, 97% coverage of query (73.2 bits)
3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
25% identity, 97% coverage of query (73.2 bits)
3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
25% identity, 97% coverage of query (72.4 bits)
2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
24% identity, 97% coverage of query (70.9 bits)
P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
24% identity, 97% coverage of query (69.7 bits)
Q3HWU8 carboxylesterase (EC 3.1.1.1) from Pseudomonas putida (see paper)
24% identity, 97% coverage of query (68.6 bits)
G3KFX4 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas sp. (see paper)
24% identity, 97% coverage of query (68.6 bits)
1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
23% identity, 97% coverage of query (68.6 bits)
1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
23% identity, 97% coverage of query (68.6 bits)
1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
23% identity, 97% coverage of query (68.6 bits)
1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
23% identity, 97% coverage of query (68.6 bits)
1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
23% identity, 97% coverage of query (68.6 bits)
1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
23% identity, 97% coverage of query (68.6 bits)
todF / P23133 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (EC 3.7.1.25) from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see paper)
TODF_PSEP1 / P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; HOHH; EC 3.7.1.25 from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / JCM 31910 / BCRC 17059 / LMG 24140 / F1) (see 2 papers)
23% identity, 94% coverage of query (66.2 bits)
cmpF / CAB06612.1 2-hydroxymuconic semialdehyde hydrolase from Sphingomonas sp (see 2 papers)
23% identity, 99% coverage of query (66.2 bits)
E3SVS0 amidase (EC 3.5.1.4) from Microbacterium hydrocarbonoxydans (see paper)
24% identity, 95% coverage of query (65.9 bits)
carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
23% identity, 97% coverage of query (65.1 bits)
Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
23% identity, 99% coverage of query (63.2 bits)
nahN / BAE92169.1 2-hydroxymuconic semialdehyde hydrolase NahN from Pseudomonas putida (see 2 papers)
24% identity, 97% coverage of query (62.8 bits)
1hl7A / Q8GJP7 Gamma lactamase from an aureobacterium species in complex with 3a,4,7, 7a-tetrahydro-benzo [1,3] dioxol-2-one (see paper)
22% identity, 94% coverage of query (62.0 bits)
PFMAB_PESFW / W3XA95 Proline iminopeptidase PfmaB; PIP; Conidial pigment biosynthesis cluster protein B; EC 3.4.11.5 from Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) (see 2 papers)
24% identity, 96% coverage of query (61.2 bits)
pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
25% identity, 74% coverage of query (60.5 bits)
5jz9A / P9WNH5 Crystal structure of hsad bound to 3,5-dichloro-4- hydroxybenzenesulphonic acid (see paper)
22% identity, 94% coverage of query (59.3 bits)
7zm4A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc31
22% identity, 94% coverage of query (59.3 bits)
7zm3A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc17
22% identity, 94% coverage of query (59.3 bits)
7zm2A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc8b
22% identity, 94% coverage of query (59.3 bits)
7zm1A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc7b
22% identity, 94% coverage of query (59.3 bits)
5jzsB Hsad bound to 3,5-dichloro-4-hydroxybenzoic acid
22% identity, 94% coverage of query (59.3 bits)
5jzbA Crystal structure of hsad bound to 3,5-dichlorobenzene sulphonamide
22% identity, 94% coverage of query (59.3 bits)
hsaD / P9WNH5 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase monomer (EC 3.7.1.17) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
HSAD_MYCTU / P9WNH5 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase; EC 3.7.1.17; EC 3.7.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNH5 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Mycobacterium tuberculosis (see paper)
22% identity, 94% coverage of query (58.9 bits)
thcF / AAC45285.1 chloroperoxidase from Rhodococcus erythropolis (see 2 papers)
23% identity, 97% coverage of query (58.5 bits)
xylF / P23106 2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas putida (see paper)
XYLF_PSEPU / P23106 2-hydroxymuconate semialdehyde hydrolase; HMSH; 2-hydroxymuconic semialdehyde hydrolase; EC 3.7.1.9 from Pseudomonas putida (Arthrobacter siderocapsulatus)
24% identity, 97% coverage of query (58.5 bits)
2wugA Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopda
22% identity, 94% coverage of query (58.2 bits)
2wufB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with 4,9dsha
22% identity, 94% coverage of query (58.2 bits)
2wueB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopoda
22% identity, 94% coverage of query (58.2 bits)
DCH_ACICA / Q83WC8 Bifunctional esterase/perhydrolase DCH; 3,4-dihydrocoumarin hydrolase; DCH; Metal-free haloperoxidase; EC 3.1.1.35 from Acinetobacter calcoaceticus (see 3 papers)
Q83WC8 dihydrocoumarin hydrolase (EC 3.1.1.35) from Acinetobacter calcoaceticus (see paper)
23% identity, 97% coverage of query (57.8 bits)
bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
20% identity, 95% coverage of query (57.8 bits)
estRB8 / CAE54381.1 carboxylesterase, partial from Oleispira antarctica (see paper)
estRB8 / CAE54384.1 carboxylesterase from Oleispira antarctica (see paper)
27% identity, 84% coverage of query (57.0 bits)
Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
25% identity, 74% coverage of query (57.0 bits)
6i8wB / Q9KJG6 Crystal structure of a membrane phospholipase a, a novel bacterial virulence factor (see paper)
22% identity, 94% coverage of query (56.6 bits)
Q9KJG6 triacylglycerol lipase (EC 3.1.1.3) from Pseudomonas aeruginosa (see paper)
22% identity, 94% coverage of query (56.6 bits)
bpdF / AAB17100.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus sp. M5 (see paper)
22% identity, 94% coverage of query (56.6 bits)
CPOA1_KITAU / P33912 Non-heme chloroperoxidase CPO-A1; CPO-A1; BPO1; Bromide peroxidase; Non-haem bromoperoxidase BPO-A1; EC 1.11.1.- from Kitasatospora aureofaciens (Streptomyces aureofaciens) (see paper)
PDB|1A8Q non-heme bromoperoxidase; EC 1.11.1.- from Streptomyces aureofaciens (see 3 papers)
bpoA1 / AAC43253.1 bromoperoxidase BPO-A1 from Kitasatospora aureofaciens (see 2 papers)
26% identity, 90% coverage of query (55.8 bits)
bphD / Q75WN8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.8) from Rhodococcus jostii (strain RHA1) (see 2 papers)
etbD / BAA18939.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus sp (see 2 papers)
21% identity, 92% coverage of query (55.5 bits)
4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
22% identity, 97% coverage of query (53.5 bits)
4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
22% identity, 97% coverage of query (53.5 bits)
4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
22% identity, 97% coverage of query (53.5 bits)
hbpD / O06648 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional] (EC 3.7.1.8) from Pseudomonas nitroreducens (see 2 papers)
20% identity, 95% coverage of query (51.6 bits)
P29715 bromide peroxidase (EC 1.11.1.18) from Kitasatospora aureofaciens (see 2 papers)
bpoA2 / GI|150457 non-heme bromoperoxidase BPO-A2; EC 1.11.1.- from Streptomyces aureofaciens (see 4 papers)
21% identity, 94% coverage of query (51.6 bits)
cpoT / GB|AAB86626.1 non-heme chloroperoxidase from Streptomyces aureofaciens (see paper)
21% identity, 94% coverage of query (51.2 bits)
MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
21% identity, 94% coverage of query (51.2 bits)
BPHL_HUMAN / Q86WA6 Valacyclovir hydrolase; VACVase; Valacyclovirase; Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA; EC 3.1.-.- from Homo sapiens (Human) (see 2 papers)
21% identity, 97% coverage of query (50.4 bits)
2ocgA / Q86WA6 Crystal structure of human valacyclovir hydrolase (see paper)
21% identity, 97% coverage of query (50.4 bits)
2ociA Crystal structure of valacyclovir hydrolase complexed with a product analogue
21% identity, 97% coverage of query (50.4 bits)
8agnAAA Alpha/beta epoxide hydrolase
23% identity, 95% coverage of query (48.5 bits)
8agmAAA Alpha/beta epoxide hydrolase
23% identity, 95% coverage of query (48.5 bits)
5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
23% identity, 96% coverage of query (48.5 bits)
8agsAAA / A0A1U9WZ52 8agsAAA
23% identity, 96% coverage of query (48.1 bits)
ABHDB_HUMAN / Q8NFV4 sn-1-specific diacylglycerol lipase ABHD11; Alpha/beta hydrolase domain-containing protein 11; Abhydrolase domain-containing protein 11; Williams-Beuren syndrome chromosomal region 21 protein; EC 3.1.1.116 from Homo sapiens (Human) (see 3 papers)
23% identity, 91% coverage of query (48.1 bits)
8agpAAA Alpha/beta epoxide hydrolase
23% identity, 95% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory