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Searching for up to 100 curated homologs for WP_012282103.1 NCBI__GCF_000019165.1:WP_012282103.1 (409 a.a.)

Found high-coverage hits (≥70%) to 87 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DAPAT_DESHD / Q18T09 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Desulfitobacterium hafniense (strain DSM 10664 / DCB-2) (see paper)
Q18T09 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Desulfitobacterium hafniense (see paper)
    80% identity, 100% coverage of query (694 bits)

DAPAT_ACET2 / A3DK17 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum) (see paper)
    72% identity, 99% coverage of query (629 bits)

DAPAT_METTH / O26158 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) (see 2 papers)
O26158 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Methanothermobacter thermautotrophicus (see paper)
    68% identity, 99% coverage of query (588 bits)

Q74GT3 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Geobacter sulfurreducens (see paper)
    65% identity, 100% coverage of query (569 bits)

Q2NFU1 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Methanosphaera stadtmanae (see paper)
    65% identity, 98% coverage of query (566 bits)

DAPAT_BACFN / Q5LC03 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / LMG 10263 / NCTC 9343 / Onslow / VPI 2553 / EN-2) (see paper)
Q5LC03 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Bacteroides fragilis (see paper)
    64% identity, 100% coverage of query (561 bits)

Q3MAL4 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Trichormus variabilis (see paper)
    62% identity, 100% coverage of query (541 bits)

DAPAT_LEPIC / Q72NJ3 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) (see paper)
Q72NJ3 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Leptospira interrogans (see 2 papers)
    61% identity, 100% coverage of query (541 bits)

DAPAT_SYNY3 / Q55828 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
Q55828 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Synechocystis sp. (see paper)
    60% identity, 100% coverage of query (530 bits)

A0A6P3CW87 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Verrucomicrobium spinosum (see 2 papers)
    58% identity, 99% coverage of query (506 bits)

DAPAT_PARUW / Q6MDE0 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Protochlamydia amoebophila (strain UWE25) (see paper)
Q6MDE0 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Candidatus Protochlamydia amoebophila (see paper)
    43% identity, 100% coverage of query (343 bits)

A8IW39 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Chlamydomonas reinhardtii (see 2 papers)
    46% identity, 98% coverage of query (333 bits)

3qguA / A8IW39 L,l-diaminopimelate aminotransferase from chlamydomonas reinhardtii (see paper)
    46% identity, 98% coverage of query (331 bits)

ALD1 / Q9ZQI7 lysine aminotransferase from Arabidopsis thaliana (see 4 papers)
ALD1_ARATH / Q9ZQI7 Aminotransferase ALD1, chloroplastic; AGD2-like defense response protein 1; EC 2.6.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q9ZQI7 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Arabidopsis thaliana (see paper)
    41% identity, 98% coverage of query (324 bits)

4fl0B / Q9ZQI7 Crystal structure of ald1 from arabidopsis thaliana (see paper)
    41% identity, 98% coverage of query (323 bits)

A0A1E7FWR0 L-methionine transaminase (EC 2.6.1.88) from Fragilariopsis cylindrus CCMP1102 (see 2 papers)
    46% identity, 99% coverage of query (318 bits)

DAP / Q93ZN9 L,L-diaminopimelate aminotransferase (EC 2.6.1.83) from Arabidopsis thaliana (see paper)
DAPAT_ARATH / Q93ZN9 LL-diaminopimelate aminotransferase, chloroplastic; AtDAP-AT; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; Protein ABERRANT GROWTH AND DEATH 2; EC 2.6.1.83 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q93ZN9 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Arabidopsis thaliana (see 4 papers)
    45% identity, 98% coverage of query (311 bits)

3ei5A Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with plp-glu: an external aldimine mimic
    45% identity, 98% coverage of query (311 bits)

2z1zA Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with l-malate ion
    45% identity, 98% coverage of query (311 bits)

3ei6A Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with plp-dap: an external aldimine mimic
    45% identity, 98% coverage of query (311 bits)

3ei9A / Q93ZN9 Crystal structure of k270n variant of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with l-glu: external aldimine form (see paper)
    45% identity, 98% coverage of query (310 bits)

3ei8A Crystal structure of k270n variant of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with ll-dap: external aldimine form
    45% identity, 98% coverage of query (309 bits)

DAPAT_CHLTR / O84395 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx) (see 2 papers)
O84395 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Chlamydia trachomatis (see 2 papers)
    39% identity, 98% coverage of query (294 bits)

O66630 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Aquifex aeolicus (see paper)
    31% identity, 98% coverage of query (165 bits)

DAPAT_SYNFM / A0LEA5 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) (see paper)
A0LEA5 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Syntrophobacter fumaroxidans (see paper)
    31% identity, 99% coverage of query (162 bits)

Q3MDN5 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Trichormus variabilis (see paper)
    30% identity, 97% coverage of query (150 bits)

Build an alignment

Build an alignment for WP_012282103.1 and 26 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

DAPAT_GLOVI / Q7NDX4 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) (see paper)
Q7NDX4 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Gloeobacter violaceus (see paper)
    29% identity, 96% coverage of query (140 bits)

Q8TQ40 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Methanosarcina acetivorans (see paper)
    29% identity, 96% coverage of query (132 bits)

bacF / P39643 3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate aminotransferase (EC 2.6.1.57) from Bacillus subtilis (strain 168) (see 2 papers)
BACF_BACSU / P39643 Transaminase BacF; Transaminase A; EC 2.6.1.- from Bacillus subtilis (strain 168) (see 3 papers)
    29% identity, 95% coverage of query (131 bits)

6l1lB / P39643 Apo-bacf structure from bacillus subtillis (see paper)
    29% identity, 95% coverage of query (131 bits)

6l1oB Product bound bacf structure from bacillus subtillis
    29% identity, 95% coverage of query (131 bits)

6l1nA Substrate bound bacf structure from bacillus subtillis
    29% identity, 95% coverage of query (130 bits)

Q8YTF2 aspartate transaminase (EC 2.6.1.1) from Nostoc sp. (see paper)
    28% identity, 97% coverage of query (127 bits)

DAPAT_MOOTA / Q2RK33 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Moorella thermoacetica (strain ATCC 39073 / JCM 9320) (see paper)
Q2RK33 LL-diaminopimelate aminotransferase (EC 2.6.1.83) from Moorella thermoacetica (see paper)
    30% identity, 96% coverage of query (121 bits)

2x5dD / Q9HV83 Crystal structure of a probable aminotransferase from pseudomonas aeruginosa (see paper)
    26% identity, 91% coverage of query (121 bits)

YfdZ / b2379 glutamate—pyruvate aminotransferase AlaC (EC 2.6.1.2) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
alaC / P77434 glutamate—pyruvate aminotransferase AlaC (EC 2.6.1.2) from Escherichia coli (strain K12) (see 4 papers)
ALAC_ECOLI / P77434 Glutamate-pyruvate aminotransferase AlaC; EC 2.6.1.2 from Escherichia coli (strain K12) (see 3 papers)
    28% identity, 91% coverage of query (115 bits)

mtnE / O31665 L-glutamine:4-(methylsulfanyl)-2-oxobutanoate aminotransferase (EC 2.6.1.117; EC 2.6.1.88) from Bacillus subtilis (strain 168) (see 3 papers)
MTNE_BACSU / O31665 L-glutamine--4-(methylsulfanyl)-2-oxobutanoate aminotransferase; GTK; Glutamine transaminase MtnE; EC 2.6.1.117 from Bacillus subtilis (strain 168) (see 3 papers)
O31665 L-glutamine-4-(methylsulfanyl)-2-oxobutanoate aminotransferase (EC 2.6.1.117) from Bacillus subtilis (see 2 papers)
    29% identity, 99% coverage of query (113 bits)

D2Z0I0 alanine-glyoxylate transaminase (EC 2.6.1.44) from Hydrogenobacter thermophilus (see paper)
    26% identity, 97% coverage of query (109 bits)

ARAT2_THELN / H3ZPU1 Aromatic-amino-acid aminotransferase 2; ARAT-II; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
    27% identity, 90% coverage of query (103 bits)

dapL / Q58786 L,L-diaminopimelate aminotransferase (EC 2.6.1.83) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
DAPAT_METJA / Q58786 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    29% identity, 85% coverage of query (102 bits)

1gd9A / O59096 Crystall structure of pyrococcus protein-a1 (see paper)
    27% identity, 91% coverage of query (101 bits)

O59096 aromatic-amino-acid transaminase (EC 2.6.1.57) from Pyrococcus horikoshii (see paper)
    27% identity, 91% coverage of query (101 bits)

1gdeA Crystal structure of pyrococcus protein a-1 e-form
    27% identity, 91% coverage of query (101 bits)

Q82IK5 succinyldiaminopimelate transaminase (EC 2.6.1.17); glutamate-prephenate aminotransferase (EC 2.6.1.79) from Streptomyces avermitilis (see paper)
    27% identity, 92% coverage of query (87.8 bits)

patA / P16524 N-acetyl-L,L-diaminopimelate aminotransferase from Bacillus subtilis (strain 168) (see 3 papers)
DAPX_BACSU / P16524 Probable N-acetyl-LL-diaminopimelate aminotransferase; Putative aminotransferase A; EC 2.6.1.- from Bacillus subtilis (strain 168) (see paper)
    25% identity, 91% coverage of query (85.1 bits)

2o1bA / Q2FV61 Structure of aminotransferase from staphylococcus aureus
    25% identity, 87% coverage of query (79.0 bits)

Q8YUK5 aspartate transaminase (EC 2.6.1.1) from Nostoc sp. (see paper)
    24% identity, 91% coverage of query (78.2 bits)

A0A6F8T0V6 aspartate transaminase (EC 2.6.1.1) from Geobacillus sp. MAS1 (see paper)
    24% identity, 92% coverage of query (72.4 bits)

A0A1D6I5Q5 L-glutamine-4-(methylsulfanyl)-2-oxobutanoate aminotransferase (EC 2.6.1.117) from Zea mays (see paper)
    30% identity, 88% coverage of query (71.6 bits)

mfnC / Q58097 2-furaldehyde phosphate aminotransferase (EC 2.6.1.108) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
MFNC_METJA / Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108) from Methanocaldococcus jannaschii (see paper)
    22% identity, 79% coverage of query (71.2 bits)

1v2eA / Q75WK2 Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
    25% identity, 90% coverage of query (70.1 bits)

BAD06364.1 aminotransferase from Thermus thermophilus (see paper)
    25% identity, 90% coverage of query (70.1 bits)

1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate
    25% identity, 90% coverage of query (70.1 bits)

Q9RAT0 aromatic-amino-acid transaminase (EC 2.6.1.57) from Lactococcus lactis (see paper)
    24% identity, 75% coverage of query (68.9 bits)

oxyQ / L8EVF8 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 2 papers)
OXYQ_STRRM / Q3S8P9 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ; PLP-dependent aminotransferase OxyQ; Reductive transaminase oxyQ; EC 2.6.1.- from Streptomyces rimosus (see paper)
    24% identity, 84% coverage of query (68.6 bits)

swb1 / D2KTX0 (2S,3R)-4-(2-aminophenyl)-2-amino-3-hydroxy-4-oxobutanoate aminotransferase from Streptomyces sp. SNA15896 (see paper)
    27% identity, 84% coverage of query (67.0 bits)

OsIDI4 / FAA00314.1 aminotransferase from Oryza sativa Japonica Group (see paper)
    29% identity, 88% coverage of query (65.1 bits)

101251438 / A0A3Q7IS73 2-oxo-4-methylthiobutanoate-glutamine aminotransferase monomer (EC 2.6.1.117) from Solanum lycopersicum (see paper)
    28% identity, 88% coverage of query (65.1 bits)

1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate
    26% identity, 90% coverage of query (65.1 bits)

1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
    26% identity, 90% coverage of query (65.1 bits)

5yhvA / P96847 Crystal structure of an aminotransferase from mycobacterium tuberculosis
    24% identity, 81% coverage of query (64.3 bits)

AVTA_MYCTU / P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    24% identity, 81% coverage of query (64.3 bits)

1o4sB / Q9X0Y2 Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
    25% identity, 91% coverage of query (64.3 bits)

AAT_THEMA / Q9X0Y2 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    25% identity, 91% coverage of query (64.3 bits)

AAPAT_THET8 / Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 5 papers)
Q56232 aspartate-prephenate aminotransferase (EC 2.6.1.78) from Thermus thermophilus (see paper)
aspC / RF|YP_143312.1 aspartate transaminase; EC 2.6.1.1 from Thermus thermophilus HB8 (see 2 papers)
    26% identity, 90% coverage of query (64.3 bits)

aspC / GB|CAA63799.1 aspartate transaminase; EC 2.6.1.1 from Geobacillus stearothermophilus (see paper)
    24% identity, 95% coverage of query (64.3 bits)

5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
    24% identity, 81% coverage of query (64.3 bits)

1bkgA Aspartate aminotransferase from thermus thermophilus with maleate
    26% identity, 90% coverage of query (64.3 bits)

1bjwA Aspartate aminotransferase from thermus thermophilus
    26% identity, 90% coverage of query (64.3 bits)

3jtxB Crystal structure of aminotransferase (np_283882.1) from neisseria meningitidis z2491 at 1.91 a resolution
    24% identity, 90% coverage of query (63.5 bits)

1j32A / Q8RR70 Aspartate aminotransferase from phormidium lapideum
aspC / BAB86290.1 aspartate aminotransferase from Phormidium lapideum (see paper)
    26% identity, 87% coverage of query (62.8 bits)

Q8NRE6 succinyldiaminopimelate transaminase (EC 2.6.1.17) from Corynebacterium glutamicum (see paper)
    24% identity, 90% coverage of query (62.4 bits)

1b5oA / Q56232 Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
    25% identity, 90% coverage of query (62.4 bits)

A2IA41 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) from Picea glauca (see paper)
    21% identity, 94% coverage of query (62.0 bits)

Y1178_MYCTU / O50434 Probable aminotransferase Rv1178; EC 2.6.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    24% identity, 73% coverage of query (61.6 bits)

CBL_BACSU / Q08432 Cystathionine beta-lyase PatB; CBL; Beta-cystathionase PatB; Cysteine lyase PatB; Cysteine-S-conjugate beta-lyase PatB; EC 4.4.1.13 from Bacillus subtilis (strain 168) (see paper)
6qp3A / Q08432 Crystal structure of the plp-bound c-s lyase from bacillus subtilis (strain 168) (see paper)
    23% identity, 70% coverage of query (57.0 bits)

3l8aB / Q8DST5 Crystal structure of metc from streptococcus mutans
    21% identity, 96% coverage of query (55.8 bits)

8wkjA / A0A130QXX8 The crystal structure of aspartate aminotransferases lpg0070 from legionella pneumophila (see paper)
    23% identity, 76% coverage of query (55.1 bits)

ISS1 / Q9C969 aromatic aminotransferase ISS1 (EC 2.6.1.27) from Arabidopsis thaliana (see paper)
ISS1_ARATH / Q9C969 Aromatic aminotransferase ISS1; Methionine aminotransferase ISS1; Phenylalanine aminotransferase ISS1; Protein INDOLE SEVERE SENSITIVE 1; Protein REVERSAL OF SAV3 PHENOTYPE 1; Tryptophan aminotransferase ISS1; Tyrosine aminotransferase ISS1; EC 2.6.1.27; EC 2.6.1.5; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C969 aromatic-amino-acid transaminase (EC 2.6.1.57) from Arabidopsis thaliana (see paper)
    24% identity, 94% coverage of query (51.6 bits)

4dq6A / Q183G9 Crystal structure of plp-bound putative aminotransferase from clostridium difficile 630
    20% identity, 96% coverage of query (51.2 bits)

5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v
    23% identity, 91% coverage of query (48.9 bits)

5wmhA Arabidopsis thaliana prephenate aminotransferase
    23% identity, 91% coverage of query (48.9 bits)

3b1eA Crystal structure of betac-s lyase from streptococcus anginosus in complex with l-serine: alpha-aminoacrylate form
    18% identity, 94% coverage of query (48.9 bits)

3b1dA Crystal structure of betac-s lyase from streptococcus anginosus in complex with l-serine: external aldimine form
    18% identity, 94% coverage of query (48.9 bits)

3b1cA / A6BMJ3 Crystal structure of betac-s lyase from streptococcus anginosus: internal aldimine form (see paper)
    18% identity, 94% coverage of query (48.9 bits)

5wmlA / Q9SIE1 Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
    22% identity, 91% coverage of query (46.6 bits)

1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
    23% identity, 77% coverage of query (44.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory