Searching for up to 100 curated homologs for WP_012333673.1 NCBI__GCF_000019365.1:WP_012333673.1 (554 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PS417_08865 large component of pyruvate transporter (actP-like) from Pseudomonas simiae WCS417
    61% identity, 98% coverage of query (649 bits)

Pf1N1B4_3673 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N1B4
    61% identity, 98% coverage of query (649 bits)

YjcG / b4067 acetate/glycolate:cation symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
actP / P32705 acetate/glycolate:cation symporter from Escherichia coli (strain K12) (see 5 papers)
ACTP_ECOLI / P32705 Cation/acetate symporter ActP; Acetate permease; Acetate transporter ActP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.21.7.2 / P32705 Acetate/glyoxylate permease, ActP from Escherichia coli (see 6 papers)
    63% identity, 95% coverage of query (640 bits)

Pf6N2E2_5849 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N2E2
    61% identity, 98% coverage of query (639 bits)

TC 2.A.21.7.1 / O50471 Phenylacetate permease, Ppa from Pseudomonas putida (see paper)
    64% identity, 92% coverage of query (619 bits)

AZOBR_RS02940 large component of pyruvate transporter (actP-like) from Azospirillum brasilense Sp245
    59% identity, 95% coverage of query (615 bits)

TC 2.A.21.7.5 / D5APM1 Acetate permease ActP-2/ActP2/ActP3 from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
    55% identity, 97% coverage of query (565 bits)

TC 2.A.21.7.4 / D5AU53 Acetate uptake permease, ActP1; also takes up tellurite from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
    57% identity, 94% coverage of query (545 bits)

MCTC_CORGL / Q8NS49 Monocarboxylic acid transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
TC 2.A.21.7.3 / Q8NS49 Pyruvate/acetate/propionate: H+ symporter, MctC (DhlC; cg0953) from Corynebacterium glutamicum (see paper)
    44% identity, 89% coverage of query (344 bits)

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Build an alignment for WP_012333673.1 and 9 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Psest_3078 L-proline:Na+ symporter from Pseudomonas stutzeri RCH2
    26% identity, 82% coverage of query (104 bits)

PUTP_BACSU / P94392 High-affinity proline transporter PutP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.21.2.4 / J7JIE8 The high affinity nutritional proline uptake porter, PutP from Bacillus subtilis QB928
    26% identity, 75% coverage of query (102 bits)

TC 2.A.21.2.3 / Q9I5F5 L-proline uptake porter, PutP from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    27% identity, 75% coverage of query (100 bits)

OPUE_BACSU / O06493 Osmoregulated proline transporter OpuE; Osmoprotectant uptake; Proline uptake system from Bacillus subtilis (strain 168) (see 2 papers)
TC 2.A.21.2.5 / M1TZ79 Proline uptake porter, OpuE (YerK) from Bacillus subtilis subsp. subtilis 6051-HGW
opuE / AAB72182.1 OpuE from Bacillus subtilis (see paper)
    25% identity, 75% coverage of query (95.5 bits)

PutC / b1015 proline:Na⁺ symporter from Escherichia coli K-12 substr. MG1655 (see 7 papers)
putP / P07117 proline:Na⁺ symporter from Escherichia coli (strain K12) (see 12 papers)
PUTP_ECOLI / P07117 Sodium/proline symporter; Proline carrier; Proline permease; Propionate transporter from Escherichia coli (strain K12) (see 9 papers)
TC 2.A.21.2.1 / P07117 Proline:Na+ symporter, PutP from Escherichia coli (see 12 papers)
    27% identity, 76% coverage of query (91.7 bits)

PUTP_STAA8 / Q2FWY7 Sodium/proline symporter; Proline permease from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
TC 2.A.21.2.2 / Q7A4Q7 Sodium/proline symporter (Proline permease) from Staphylococcus aureus (strain N315) (see paper)
    24% identity, 85% coverage of query (88.6 bits)

putP / AAA79365.1 proline permease homolog from Staphylococcus aureus (see paper)
    24% identity, 84% coverage of query (87.4 bits)

PUTP_SALTY / P10502 Sodium/proline symporter; Proline permease from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    26% identity, 75% coverage of query (84.7 bits)

TC 2.A.21.2.6 / O24896 High affinity proline-specific Na+:proline symporter, PutP (Rivera-Ordaz et al. 2013).  Proline is a preferred source of energy for this microaerophilic bacterium.  PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid from Helicobacter pylori (strain ATCC 700392 / 26695)
    21% identity, 75% coverage of query (75.5 bits)

SC5A6_HUMAN / Q9Y289 Sodium-dependent multivitamin transporter; Na(+)-dependent multivitamin transporter; hSMVT; Solute carrier family 5 member 6 from Homo sapiens (Human) (see 13 papers)
TC 2.A.21.5.7 / Q9Y289 Sodium-dependent multivitamin transporter (Na+-dependent multivitamin transporter) (Solute carrier family 5 member 6) from Homo sapiens (see 5 papers)
    22% identity, 85% coverage of query (44.7 bits)

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