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Searching for up to 100 curated homologs for WP_012383230.1 NCBI__GCF_000019845.1:WP_012383230.1 (201 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

LEUD_RHIJ3 / Q1MA52 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    75% identity, 100% coverage of query (323 bits)

O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    60% identity, 100% coverage of query (247 bits)

leuD / BAC65258.1 3-isopropylmalate dehydratase small subunit from Burkholderia multivorans (see paper)
    57% identity, 100% coverage of query (242 bits)

AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
    60% identity, 100% coverage of query (242 bits)

leuD / Q8F4E5 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see paper)
    54% identity, 100% coverage of query (227 bits)

hbzJ / Q0QFQ6 maleate hydratase small subunit (EC 4.2.1.31) from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ6 maleate hydratase (subunit 1/2) (EC 4.2.1.31) from Pseudomonas alcaligenes (see paper)
    52% identity, 100% coverage of query (223 bits)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    56% identity, 100% coverage of query (221 bits)

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    53% identity, 96% coverage of query (211 bits)

LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
    52% identity, 96% coverage of query (207 bits)

leu1 / CAB99455.1 3-isopropylmalate dehydratase, partial from Yarrowia lipolytica (see paper)
    60% identity, 87% coverage of query (201 bits)

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    49% identity, 97% coverage of query (180 bits)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis (see paper)
    45% identity, 95% coverage of query (161 bits)

P9WK95 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    45% identity, 95% coverage of query (161 bits)

AMT8_ALTAL / C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    35% identity, 77% coverage of query (68.9 bits)

HtyD / K0E2G4 2-(4-hydroxybenzyl)-malate isomerase from Aspergillus rugulosus (see paper)
HTYD_ASPRU / K0E2G4 Aconitase htyD; L-homotyrosine biosynthetic cluster protein D; EC 4.2.1.- from Aspergillus rugulosus (Emericella rugulosa) (see paper)
    37% identity, 72% coverage of query (64.7 bits)

IPMI2 / Q9ZW84 isopropylmalate isomerase, small subunit (EC 4.2.1.170) from Arabidopsis thaliana (see paper)
LEUD1_ARATH / Q9ZW84 3-isopropylmalate dehydratase small subunit 2; 2-(omega-methylthio)alkylmalate dehydratase small subunit 2; AtLEUD1; Isopropylmalate isomerase 2; Isopropylmalate isomerase small subunit 2; IPMI SSU2; Methylthioalkylmalate isomerase small subunit; MAM-IS; EC 4.2.1.33; EC 4.2.1.170 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9ZW84 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
    34% identity, 72% coverage of query (64.3 bits)

lysU / Q9ZND9 homoaconitase small subunit (EC 4.2.1.36) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
HACB_THET2 / Q9ZND9 Homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.36 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
    31% identity, 77% coverage of query (62.8 bits)

lysF / GI|1628374 homoaconitase, mitochondrial; EC 4.2.1.36 from Emericella nidulans (see paper)
    32% identity, 72% coverage of query (56.6 bits)

LYS4_EMENI / Q92412 Homoaconitase, mitochondrial; Homoaconitate hydratase; EC 4.2.1.36 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
Q92412 homoaconitate hydratase (EC 4.2.1.36) from Aspergillus nidulans (see paper)
    32% identity, 72% coverage of query (56.6 bits)

Build an alignment

Build an alignment for WP_012383230.1 and 19 homologs with ≥ 30% identity

Select sequences

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory