Searching for up to 100 curated homologs for WP_012384393.1 NCBI__GCF_000019845.1:WP_012384393.1 (597 a.a.)
Found high-coverage hits (≥70%) to 33 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CCNA_01969 aspartyl-tRNA(Asp/Asn) synthetase (EC 6.1.1.23) from Caulobacter crescentus NA1000
60% identity, 99% coverage of query (732 bits)
PGA1_c24530 aspartyl-tRNA(Asp/Asn) synthetase (EC 6.1.1.23) from Phaeobacter inhibens BS107
58% identity, 99% coverage of query (720 bits)
Dshi_2633 aspartyl-tRNA(Asp/Asn) synthetase (EC 6.1.1.23) from Dinoroseobacter shibae DFL-12
58% identity, 99% coverage of query (711 bits)
O32038 aspartate-tRNAAsn ligase (EC 6.1.1.23) from Bacillus subtilis (see paper)
44% identity, 98% coverage of query (488 bits)
Q9KDG1 aspartate-tRNAAsn ligase (EC 6.1.1.23) from Alkalihalobacillus halodurans (see paper)
43% identity, 98% coverage of query (480 bits)
4wj3M / Q51422 Crystal structure of the asparagine transamidosome from pseudomonas aeruginosa (see paper)
44% identity, 98% coverage of query (476 bits)
SYDND_PSEAE / Q51422 Aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase; AspRS; Non-discriminating aspartyl-tRNA synthetase; ND-AspRS; EC 6.1.1.23 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
44% identity, 98% coverage of query (476 bits)
4wj4A Crystal structure of non-discriminating aspartyl-tRNA synthetase from pseudomonas aeruginosa complexed with tRNA(asn) and aspartic acid
44% identity, 98% coverage of query (476 bits)
SYDND_HELPY / P56459 Aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase; AspRS; Non-discriminating aspartyl-tRNA synthetase; ND-AspRS; EC 6.1.1.23 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
P56459 aspartate-tRNA ligase (EC 6.1.1.12) from Helicobacter pylori (see paper)
43% identity, 98% coverage of query (470 bits)
Synpcc7942_1313 aspartyl-tRNA(Asp/Asn) synthetase (EC 6.1.1.23) from Synechococcus elongatus PCC 7942
43% identity, 98% coverage of query (468 bits)
DvMF_2038 aspartyl-tRNA(Asp/Asn) synthetase (EC 6.1.1.23) from Desulfovibrio vulgaris Miyazaki F
41% identity, 98% coverage of query (452 bits)
Q6MI59 aspartate-tRNAAsn ligase (EC 6.1.1.23) from Bdellovibrio bacteriovorus (see paper)
41% identity, 98% coverage of query (451 bits)
4rmfA Biochemical and structural characterization of mycobacterial aspartyl- tRNA synthetase asps, a promising tb drug target
44% identity, 97% coverage of query (445 bits)
Tls / b1866 aspartate—tRNA ligase (EC 6.1.1.12) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
aspS / P21889 aspartate—tRNA ligase (EC 6.1.1.12; EC 6.1.1.23) from Escherichia coli (strain K12) (see 26 papers)
SYD_ECOLI / P21889 Aspartate--tRNA ligase; Aspartyl-tRNA synthetase; AspRS; EC 6.1.1.12 from Escherichia coli (strain K12) (see paper)
41% identity, 98% coverage of query (444 bits)
1c0aA / P21889 Crystal structure of the e. Coli aspartyl-tRNA synthetase : trnaasp : aspartyl-adenylate complex (see paper)
41% identity, 98% coverage of query (444 bits)
SYDND_CHLTR / O84546 Aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase; AspRS; Non-discriminating aspartyl-tRNA synthetase; ND-AspRS; EC 6.1.1.23 from Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx) (see paper)
42% identity, 99% coverage of query (441 bits)
P9WFW3 aspartate-tRNA ligase (EC 6.1.1.12) from Mycobacterium tuberculosis (see paper)
43% identity, 98% coverage of query (440 bits)
5w25A / P9WFW3 Crystal structure of aspartyl-tRNA synthetase from mycobacterium tuberculosis complexed with l-aspartic acid
43% identity, 97% coverage of query (439 bits)
4o2dA / A0QWN3 Crystal structure of aspartyl-tRNA synthetase from mycobacterium smegmatis with bound aspartic acid (see paper)
43% identity, 98% coverage of query (437 bits)
6sjcB / Q5SKD2 Structure of t. Thermophilus asprs in complex with 5'-o-(n-(l- aspartyl)-sulfamoyl)adenosine (see paper)
43% identity, 99% coverage of query (431 bits)
SYD_THETH / P36419 Aspartate--tRNA(Asp) ligase; Aspartyl-tRNA synthetase; AspRS; Discriminating aspartyl-tRNA synthetase; D-AspRS; EC 6.1.1.12 from Thermus thermophilus (see 2 papers)
SYD_THET8 / Q5SKD2 Aspartate--tRNA(Asp) ligase; Aspartyl-tRNA synthetase 1; AspRS1; Discriminating aspartyl-tRNA synthetase; D-AspRS; EC 6.1.1.12 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
P36419 aspartate-tRNA ligase (EC 6.1.1.12) from Thermus thermophilus (see 2 papers)
43% identity, 99% coverage of query (431 bits)
1g51B Aspartyl tRNA synthetase from thermus thermophilus at 2.4 a resolution
43% identity, 99% coverage of query (431 bits)
1g51A Aspartyl tRNA synthetase from thermus thermophilus at 2.4 a resolution
43% identity, 99% coverage of query (431 bits)
1efwA Crystal structure of aspartyl-tRNA synthetase from thermus thermophilus complexed to trnaasp from escherichia coli
43% identity, 99% coverage of query (431 bits)
6hhxA Structure of t. Thermophilus asprs in complex with 5'-o-(n-(l- aspartyl)-sulfamoyl)cytidine
43% identity, 98% coverage of query (420 bits)
6hhwA Structure of t. Thermophilus asprs in complex with 5'-o-(n-(l- aspartyl)-sulfamoyl)uridine
43% identity, 98% coverage of query (420 bits)
6hhvA Structure of t. Thermophilus asprs in complex with 5'-o-(n-(l- aspartyl)-sulfamoyl)n3-methyluridine
43% identity, 98% coverage of query (420 bits)
SYDM_ARATH / F4JJT9 Aspartate--tRNA ligase, chloroplastic/mitochondrial; Aspartyl-tRNA synthetase; AspRS; EC 6.1.1.12 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
39% identity, 98% coverage of query (417 bits)
aspS1 / Q9RUN7 aspartyl-tRNA synthetase subunit (EC 6.1.1.23) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see 2 papers)
SYD_DEIRA / Q9RUN7 Aspartate--tRNA(Asp) ligase; Aspartyl-tRNA synthetase 1; AspRS1; Discriminating aspartyl-tRNA synthetase; D-AspRS; EC 6.1.1.12 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
40% identity, 96% coverage of query (412 bits)
7ap4A Thermus thermophilus aspartyl-tRNA synthetase in complex with compound asps7hmdda
43% identity, 98% coverage of query (412 bits)
SYDM_HUMAN / Q6PI48 Aspartate--tRNA ligase, mitochondrial; Aspartyl-tRNA synthetase; AspRS; EC 6.1.1.12 from Homo sapiens (Human) (see 4 papers)
Q6PI48 aspartate-tRNA ligase (EC 6.1.1.12) from Homo sapiens (see 3 papers)
34% identity, 99% coverage of query (350 bits)
SYDM_SCHPO / O94242 Aspartate--tRNA ligase, mitochondrial; Aspartyl-tRNA synthetase; AspRS; EC 6.1.1.12 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 94% coverage of query (253 bits)
SYDM_YEAST / P15179 Aspartate--tRNA ligase, mitochondrial; Aspartyl-tRNA synthetase; AspRS; EC 6.1.1.12 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
30% identity, 97% coverage of query (217 bits)
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Lawrence Berkeley National Laboratory