Searching for up to 100 curated homologs for WP_012385833.1 NCBI__GCF_000019845.1:WP_012385833.1 (154 a.a.)
Found high-coverage hits (≥70%) to 17 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PtsN / b3204 phosphotransferase system enzyme IIA(Ntr) from Escherichia coli K-12 substr. MG1655 (see 22 papers)
ptsN / AAB60165.1 Enzyme IIANtr from Escherichia coli (see 3 papers)
38% identity, 95% coverage of query (102 bits)
PTFA_HALVD / D4GYE4 PTS system fructose-specific EIIA component; EIIA-Fru; Fructose-specific phosphotransferase enzyme IIA component from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
TC 4.A.2.1.15 / D4GYE4 Sugar phosphotransferase system IIA component, component of Fructose-specific PTS, PtfABC from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see paper)
40% identity, 80% coverage of query (80.5 bits)
TC 4.A.2.1.20 / Q3K0G6 Chromosomal fructose Enzyme IIABC (Fru1) of 654 aas; in an operon with fructose-1-P kinase from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
32% identity, 88% coverage of query (77.0 bits)
TC 4.A.2.1.14 / D2RXA7 Putative PTS IIA-like nitrogen-regulatory protein PtsN, component of Fructose Enzyme II complex (IIAFru - IIBFru - IICFru) (based on homology) from Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (see paper)
37% identity, 95% coverage of query (77.0 bits)
TC 4.A.2.1.26 / Q5V5X4 Sugar hosphotransferase system IIA component, component of Fructose-specific Enzyme I-HPr-Enzyme IIABC complex, all encoded within a single operon with genes in the order: ptsC (IIC), ptsA (IIA), ptsH (HPr), ptsI (Enzyme I) and ptsB (IIB) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
33% identity, 94% coverage of query (76.3 bits)
Build an alignment for WP_012385833.1 and 5 homologs with ≥ 30% identity
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TC 4.A.2.1.7 / Q1LZ59 The fructose inducible fructose/xylitol porter, FruI from Streptococcus mutans UA159 (see paper)
29% identity, 99% coverage of query (74.3 bits)
TC 4.A.2.1.4 / P71012 The fructose porter, FruA (fructose-1-P forming IIABC) (Delobbe et al. 1975) FruA is 39% identical to 4.A.2.1.1). fructose can be metabolized to Fru-1-P via this system as well as Fru-6-P by another PTS system from Bacillus subtilis (see paper)
27% identity, 97% coverage of query (69.3 bits)
TC 4.A.2.1.16 / Q9RMF5 Fructose-specific Enzyme IIABC from Spiroplasma citri
31% identity, 73% coverage of query (65.5 bits)
PTN3B_BACSU / O31645 PTS system mannose-specific EIIBCA component; EIIBCA-Man; EII-Man; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see 2 papers)
O31645 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Bacillus subtilis (see paper)
TC 4.A.2.1.6 / O31645 The mannose porter (ManP) (37% identical to 4.A.2.1.1). It is encoded in an operon with 3 genes: from Bacillus subtilis (see 5 papers)
30% identity, 95% coverage of query (63.2 bits)
FryA / b2383 putative PTS multiphosphoryl transfer protein FryA from Escherichia coli K-12 substr. MG1655 (see 4 papers)
fryA / RF|NP_416884 multiphosphoryl transfer protein 1 from Escherichia coli K12 (see paper)
31% identity, 94% coverage of query (61.6 bits)
TC 4.A.2.1.9 / Q1R4S9 Putative phosphotransferase system (PTS), fructose-specific, component of The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence from Escherichia coli (strain UTI89 / UPEC) (see paper)
30% identity, 86% coverage of query (60.5 bits)
MngA 2-O-α-mannosyl-D-glycerate specific PTS enzyme II (EC 2.7.1.195) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
MngA / P54745 2-O-α-mannosyl-D-glycerate specific PTS enzyme II (EC 2.7.1.195) from Escherichia coli (strain K12) (see 5 papers)
MNGA_ECOLI / P54745 PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC component; 2-O-alpha-mannosyl-D-glycerate-specific phosphotransferase enzyme MngA; Protein-Npi-phosphohistidine--2-O-alpha-mannosyl-D-glycerate phosphotransferase; EC 2.7.1.195 from Escherichia coli (strain K12) (see 2 papers)
P54745 protein-Npi-phosphohistidine-2-O-alpha-mannosyl-D-glycerate phosphotransferase (EC 2.7.1.195) from Escherichia coli (see paper)
TC 4.A.2.1.3 / P54745 The 2-O-α-mannosyl D-glycerate porter (2-O-α-mannosyl D-glycerate-6-P forming), MngA (HrsA) from Escherichia coli (see 5 papers)
33% identity, 77% coverage of query (60.5 bits)
LicR / VIMSS279545 LicR regulator of Beta-glucosides utilization, effector HPr, phosphocarrier protein; LicB, lichenan-specific enzyme IIB PTS component (activator) from Oceanobacillus iheyensis HTE831
25% identity, 95% coverage of query (56.2 bits)
LicR / VIMSS821935 LicR regulator of Beta-glucosides utilization, effector HPr, phosphocarrier protein; LicB, lichenan-specific enzyme IIB PTS component (activator) from Bacillus clausii KSM-K16
23% identity, 86% coverage of query (48.5 bits)
P46321 Probable licABCH operon regulator; EC 2.7.1.- from Bacillus subtilis (strain 168)
28% identity, 75% coverage of query (48.1 bits)
TC 4.A.2.1.12 / Q9KKQ7 The mannitol/glucitol transporter, MtlA (IICBAMtl) from Vibrio cholerae (see paper)
26% identity, 90% coverage of query (46.6 bits)
LicR / VIMSS3457956 LicR regulator of Beta-glucosides utilization, effector HPr, phosphocarrier protein; LicB, lichenan-specific enzyme IIB PTS component (activator) from Bacillus amyloliquefaciens FZB42
27% identity, 86% coverage of query (46.6 bits)
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Lawrence Berkeley National Laboratory