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Searching for up to 100 curated homologs for WP_012400680.1 NCBI__GCF_000020045.1:WP_012400680.1 (396 a.a.)

Found high-coverage hits (≥70%) to 10 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

fabX / O25465 decanoate oxidase (EC 1.3.3.6; EC 5.3.3.14) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
    33% identity, 94% coverage of query (168 bits)

7e1qA / A0A0B2E3F3 Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori (see paper)
    33% identity, 94% coverage of query (168 bits)

7e1sC Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with octanoyl-acp
    33% identity, 94% coverage of query (168 bits)

7e1sA Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with octanoyl-acp
    33% identity, 94% coverage of query (168 bits)

7e1rA Crystal structure of dehydrogenase/isomerase fabx from helicobacter pylori in complex with holo-acp
    33% identity, 94% coverage of query (168 bits)

Build an alignment

Build an alignment for WP_012400680.1 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

fabK / D4YGY7 enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.9) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    26% identity, 91% coverage of query (76.6 bits)

7l00C / A0A031WIF2 Crystal structure of c. Difficile enoyl-acyl carrier protein reductase (fabk) in complex with an inhibitor
    24% identity, 92% coverage of query (71.2 bits)

5gvhA / Q9WZQ7 Structure of fabk from thermotoga maritima (see paper)
    25% identity, 91% coverage of query (62.0 bits)

2z6iB / Q9FBC5 Crystal structure of s. Pneumoniae enoyl-acyl carrier protein reductase (fabk) (see paper)
    27% identity, 72% coverage of query (60.5 bits)

fabK / Q9FBC5 enoyl-[acyl-carrier-protein] reductase (NADH) monomer (EC 1.3.1.9) from Streptococcus pneumoniae (see 8 papers)
fabK / AAF98273.1 trans-2-enoyl-ACP reductase II from Streptococcus pneumoniae (see paper)
    27% identity, 72% coverage of query (60.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory