Searching for up to 100 curated homologs for WP_012401500.1 NCBI__GCF_000020045.1:WP_012401500.1 (398 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Ac3H11_1358 L-leucine transaminase; L-isoleucine transaminase (EC 2.6.1.42) from Acidovorax sp. GW101-3H11
54% identity, 92% coverage of query (383 bits)
O57946 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Pyrococcus horikoshii (see paper)
45% identity, 96% coverage of query (356 bits)
3aovA / O57946 Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with plp
45% identity, 96% coverage of query (356 bits)
3wx9A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, gla, 4ad, 2og, glu and kya
45% identity, 96% coverage of query (356 bits)
3av7A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, kyn as substrates and kya as products
45% identity, 96% coverage of query (356 bits)
3aowC Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with akg
45% identity, 96% coverage of query (356 bits)
ARAT1_THELN / H3ZPL1 Aromatic-amino-acid aminotransferase 1; ARAT-I; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
45% identity, 99% coverage of query (353 bits)
A0A060PQX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermococcus sp. (see paper)
45% identity, 99% coverage of query (352 bits)
AZOBR_RS06555 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Azospirillum brasilense Sp245
43% identity, 96% coverage of query (338 bits)
1wstA / Q9V2W5 Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus
43% identity, 96% coverage of query (337 bits)
lysN / Q5SL82 L-2-aminoadipate aminotransferase monomer (EC 2.6.1.39) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
46% identity, 97% coverage of query (335 bits)
LYSN_THET2 / Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
Q72LL6 2-aminoadipate transaminase (EC 2.6.1.39) from Thermus thermophilus (see paper)
2zyjA / Q72LL6 Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
46% identity, 95% coverage of query (334 bits)
3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27
46% identity, 95% coverage of query (334 bits)
2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
46% identity, 95% coverage of query (334 bits)
2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
46% identity, 95% coverage of query (321 bits)
Ac3H11_1015 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Acidovorax sp. GW101-3H11
41% identity, 96% coverage of query (305 bits)
BWI76_RS24235 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Klebsiella michiganensis M5al
39% identity, 96% coverage of query (274 bits)
1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
37% identity, 96% coverage of query (262 bits)
Aadat / Q64602 α-aminoadipate aminotransferase subunit (EC 2.6.1.39) from Rattus norvegicus (see paper)
AADAT_RAT / Q64602 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Rattus norvegicus (Rat) (see paper)
Q64602 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Rattus norvegicus (see 2 papers)
33% identity, 95% coverage of query (207 bits)
4gdyB / Q8N5Z0 Kynurenine aminotransferase ii inhibitors
32% identity, 94% coverage of query (196 bits)
AADAT / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (EC 2.6.1.7; EC 2.6.1.39) from Homo sapiens (see 5 papers)
AADAT_HUMAN / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Homo sapiens (Human) (see 4 papers)
Q8N5Z0 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Homo sapiens (see 16 papers)
32% identity, 94% coverage of query (196 bits)
2vgzA Crystal structure of human kynurenine aminotransferase ii
32% identity, 91% coverage of query (196 bits)
4ge4A Kynurenine aminotransferase ii inhibitors
32% identity, 90% coverage of query (196 bits)
4gebA Kynurenine aminotransferase ii inhibitors
32% identity, 94% coverage of query (196 bits)
4ge9A Kynurenine aminotransferase ii inhibitors
32% identity, 94% coverage of query (196 bits)
4ge7A Kynurenine aminotransferase ii inhibitors
32% identity, 94% coverage of query (196 bits)
5tf5A Crystal structure of human kat-2 in complex with a reversible inhibitor
32% identity, 94% coverage of query (196 bits)
2r2nA The crystal structure of human kynurenine aminotransferase ii in complex with kynurenine
32% identity, 94% coverage of query (196 bits)
6t8qA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
32% identity, 94% coverage of query (196 bits)
2xh1A Crystal structure of human kat ii-inhibitor complex
32% identity, 91% coverage of query (195 bits)
3ue8A Kynurenine aminotransferase ii inhibitors
32% identity, 90% coverage of query (194 bits)
AADAT_MOUSE / Q9WVM8 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Mus musculus (Mouse) (see paper)
Q9WVM8 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus (see paper)
31% identity, 90% coverage of query (189 bits)
YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
32% identity, 93% coverage of query (187 bits)
2zc0A / Q9C4M4 Crystal structure of an archaeal alanine:glyoxylate aminotransferase (see paper)
30% identity, 97% coverage of query (187 bits)
6t8pA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
31% identity, 91% coverage of query (186 bits)
Build an alignment for WP_012401500.1 and 35 homologs with ≥ 30% identity
Or download the sequences
YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
29% identity, 97% coverage of query (172 bits)
DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
29% identity, 93% coverage of query (171 bits)
8tn3A / Q643B9 Structure of s. Hygroscopicus aminotransferase mppq complexed with pyridoxamine 5'-phosphate (pmp) (see paper)
34% identity, 89% coverage of query (164 bits)
NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
23% identity, 97% coverage of query (162 bits)
DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
28% identity, 94% coverage of query (162 bits)
tdiD / A7XRY8 L-tryptophan:phenylpyruvate aminotransferase (EC 2.6.1.28) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see 3 papers)
TDID_EMENI / A7XRY8 Aminotransferase tdiD; Terrequinone biosynthesis protein D; EC 2.6.1.28 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 5 papers)
A7XRY8 tryptophan-phenylpyruvate transaminase (EC 2.6.1.28) from Aspergillus nidulans (see 2 papers)
30% identity, 97% coverage of query (160 bits)
DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
29% identity, 93% coverage of query (156 bits)
DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
28% identity, 88% coverage of query (154 bits)
DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
27% identity, 94% coverage of query (150 bits)
YdcR / b1439 fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydcR / MB|P77730 uncharacterized HTH-type transcriptional regulator ydcR from Escherichia coli K12 (see 3 papers)
27% identity, 95% coverage of query (149 bits)
YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
27% identity, 93% coverage of query (147 bits)
tdiD putative aminotransferase from Emericella nidulans (see paper)
29% identity, 97% coverage of query (147 bits)
DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
28% identity, 94% coverage of query (139 bits)
DVU0030 / VIMSS8501445 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris str. Miyazaki F
26% identity, 93% coverage of query (136 bits)
YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
29% identity, 79% coverage of query (136 bits)
S4UF58 tryptophan transaminase (EC 2.6.1.27) from Malassezia furfur (see paper)
28% identity, 94% coverage of query (135 bits)
6s8wC / Q4X0F7 Aromatic aminotransferase aroh (aro8) form aspergillus fumigatus in complex with plp (internal aldimine)
27% identity, 96% coverage of query (135 bits)
HPGT_AMYOR / O52815 (S)-3,5-dihydroxyphenylglycine transaminase; p-hydroxyphenylglycine transaminase; EC 2.6.1.103 from Amycolatopsis orientalis (Nocardia orientalis) (see 2 papers)
30% identity, 92% coverage of query (131 bits)
A0A0D1E3F3 tryptophan transaminase (EC 2.6.1.27) from Ustilago maydis (see paper)
29% identity, 96% coverage of query (130 bits)
6s8wB / Q4X0F7 Aromatic aminotransferase aroh (aro8) form aspergillus fumigatus in complex with plp (internal aldimine)
27% identity, 93% coverage of query (129 bits)
TAUR_RHOCB / D5AKX9 HTH-type transcriptional regulator TauR from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
34% identity, 75% coverage of query (126 bits)
AATR1_SCHPO / O14192 Aromatic amino acid aminotransferase C56E4.03; EC 2.6.1.57 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
26% identity, 92% coverage of query (123 bits)
6hnuB / C4YJ02 Crystal structure of the aminotransferase aro8 from c. Albicans with ligands (see paper)
24% identity, 97% coverage of query (121 bits)
A0A1D8PG20 2-aminoadipate transaminase (EC 2.6.1.39); aromatic-amino-acid transaminase (EC 2.6.1.57) from Candida albicans (see 2 papers)
23% identity, 97% coverage of query (116 bits)
AATR3_SCHPO / Q9Y7S6 Aromatic amino acid aminotransferase C569.07; EC 2.6.1.57 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
23% identity, 90% coverage of query (115 bits)
A0A1D8PPA8 aromatic-amino-acid transaminase (EC 2.6.1.57) from Candida albicans (see paper)
26% identity, 90% coverage of query (112 bits)
CH_124006 amino transferase [Aspergillus fumigatus] from Magnaporthe grisea 70-15 (see paper)
24% identity, 91% coverage of query (110 bits)
patA / P16524 N-acetyl-L,L-diaminopimelate aminotransferase from Bacillus subtilis (strain 168) (see 3 papers)
DAPX_BACSU / P16524 Probable N-acetyl-LL-diaminopimelate aminotransferase; Putative aminotransferase A; EC 2.6.1.- from Bacillus subtilis (strain 168) (see paper)
28% identity, 96% coverage of query (105 bits)
AATR2_SCHPO / O94570 Aromatic amino acid aminotransferase C1773.13; EC 2.6.1.57 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
23% identity, 92% coverage of query (103 bits)
6uxzB (S)-4-amino-5-phenoxypentanoate as a selective agonist of the transcription factor gabr
27% identity, 90% coverage of query (101 bits)
5t4kA Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation
27% identity, 90% coverage of query (100 bits)
5t4jB Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation
27% identity, 90% coverage of query (100 bits)
SWNA_ARTBC / D4AU29 Aminotransferase swnA; Swainsonine biosynthesis gene cluster protein A; EC 2.6.1.- from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see paper)
26% identity, 73% coverage of query (97.8 bits)
5x03B / P94426 Crystal structure of thE C-terminal domain of bacillus subtilis gabr reveals a closed conformation by the binding of gamma-aminobutyric acid, inducing the transcriptional activation (see paper)
27% identity, 76% coverage of query (97.4 bits)
GABR_BACSU / P94426 HTH-type transcriptional regulatory protein GabR from Bacillus subtilis (strain 168) (see 2 papers)
27% identity, 76% coverage of query (97.4 bits)
6hnvB Crystal structure of aminotransferase aro9 from c. Albicans with ligands
26% identity, 88% coverage of query (97.4 bits)
6hnvA Crystal structure of aminotransferase aro9 from c. Albicans with ligands
26% identity, 88% coverage of query (97.4 bits)
7pq9AAA PLP-dependent aminotransferase family protein
25% identity, 86% coverage of query (94.7 bits)
6hndB / A0A1D8PMC5 Crystal structure of the aromatic aminotransferase aro9 from c. Albicans (see paper)
26% identity, 88% coverage of query (94.4 bits)
7zn5B / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
25% identity, 86% coverage of query (94.4 bits)
7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
25% identity, 86% coverage of query (94.4 bits)
4je5B / P53090 Crystal structure of the aromatic aminotransferase aro8, a putative alpha-aminoadipate aminotransferase in saccharomyces cerevisiae (see paper)
23% identity, 97% coverage of query (92.0 bits)
4je5A Crystal structure of the aromatic aminotransferase aro8, a putative alpha-aminoadipate aminotransferase in saccharomyces cerevisiae
24% identity, 92% coverage of query (91.7 bits)
1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate
28% identity, 87% coverage of query (90.5 bits)
1v2eA / Q75WK2 Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
28% identity, 87% coverage of query (90.5 bits)
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
23% identity, 98% coverage of query (85.9 bits)
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate
27% identity, 77% coverage of query (80.9 bits)
1bjwA Aspartate aminotransferase from thermus thermophilus
27% identity, 77% coverage of query (80.9 bits)
AAPAT_THET8 / Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 5 papers)
Q56232 aspartate-prephenate aminotransferase (EC 2.6.1.78) from Thermus thermophilus (see paper)
aspC / RF|YP_143312.1 aspartate transaminase; EC 2.6.1.1 from Thermus thermophilus HB8 (see 2 papers)
27% identity, 77% coverage of query (80.9 bits)
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate
27% identity, 77% coverage of query (80.5 bits)
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
27% identity, 77% coverage of query (80.5 bits)
1b5oA / Q56232 Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
27% identity, 77% coverage of query (80.1 bits)
1o4sB / Q9X0Y2 Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
25% identity, 91% coverage of query (79.0 bits)
1gdeA Crystal structure of pyrococcus protein a-1 e-form
24% identity, 97% coverage of query (70.9 bits)
1gd9A / O59096 Crystall structure of pyrococcus protein-a1 (see paper)
24% identity, 97% coverage of query (70.9 bits)
1xi9C / Q9P9M8 Alanine aminotransferase from pyrococcus furiosus pfu-1397077-001
24% identity, 91% coverage of query (70.5 bits)
8ffuA Structure of gntc, a plp-dependent enzyme catalyzing l-enduracididine biosynthesis from (s)-4-hydroxy-l-arginine, with the substrate bound (see paper)
25% identity, 78% coverage of query (67.4 bits)
3if2A / Q4FPU3 Crystal structure of putative amino-acid aminotransferase (yp_265399.1) from psychrobacter arcticum 273-4 at 2.50 a resolution
25% identity, 75% coverage of query (66.6 bits)
1j32A / Q8RR70 Aspartate aminotransferase from phormidium lapideum
aspC / BAB86290.1 aspartate aminotransferase from Phormidium lapideum (see paper)
25% identity, 91% coverage of query (65.9 bits)
Tat / P04694 tyrosine aminotransferase subunit (EC 2.6.1.1) from Rattus norvegicus (see 10 papers)
ATTY_RAT / P04694 Tyrosine aminotransferase; TAT; L-tyrosine:2-oxoglutarate aminotransferase; EC 2.6.1.5 from Rattus norvegicus (Rat) (see 2 papers)
26% identity, 81% coverage of query (65.9 bits)
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v
24% identity, 77% coverage of query (64.3 bits)
ISS1 / Q9C969 aromatic aminotransferase ISS1 (EC 2.6.1.27) from Arabidopsis thaliana (see paper)
ISS1_ARATH / Q9C969 Aromatic aminotransferase ISS1; Methionine aminotransferase ISS1; Phenylalanine aminotransferase ISS1; Protein INDOLE SEVERE SENSITIVE 1; Protein REVERSAL OF SAV3 PHENOTYPE 1; Tryptophan aminotransferase ISS1; Tyrosine aminotransferase ISS1; EC 2.6.1.27; EC 2.6.1.5; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C969 aromatic-amino-acid transaminase (EC 2.6.1.57) from Arabidopsis thaliana (see paper)
25% identity, 81% coverage of query (64.3 bits)
5wmhA Arabidopsis thaliana prephenate aminotransferase
24% identity, 77% coverage of query (64.3 bits)
3dydA / P17735 Human tyrosine aminotransferase
25% identity, 81% coverage of query (63.9 bits)
6l1oB Product bound bacf structure from bacillus subtillis
25% identity, 81% coverage of query (63.5 bits)
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